Strain echocardiography is related to fibrosis and ventricular arrhythmias in hypertrophic cardiomyopathy

European Heart Journal Cardiovascular Imaging

Volumn 17, Issue 6, 2016, Pages 613-621

  Haland, Trine F ^a,b,c   Almaas, Vibeke M ^a,b,c   Hasselberg, Nina E ^a,b,c   Saberniak, Jørg ^a,b,c   Leren, Ida S ^a,b,c   Hopp, Einar ^a,b,c   Edvardsen, Thor ^a,b,c   Haugaa, Kristina H ^a,b,c  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c UNIVERSITY OF OSLO   (Norway)

Author keywords

Hypertrophic Cardiomyopathy; Strain Echocardiography And Cardiac Magnetic Resonance; Ventricular Arrhythmia

Indexed keywords

GADOLINIUM PENTETATE MEGLUMINE;

ADULT; ARTICLE; CARDIOVASCULAR MAGNETIC RESONANCE; CARDIOVASCULAR PARAMETERS; CONTRAST ENHANCEMENT; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; FEMALE; GLOBAL LONGITUDINAL STRAIN; HEART ARREST; HEART EJECTION FRACTION; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE FIBROSIS; HEART VENTRICLE ARRHYTHMIA; HEART VENTRICLE TACHYCARDIA; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; MAJOR CLINICAL STUDY; MALE; MECHANICAL DISPERSION; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE SCANNER; PRIORITY JOURNAL; REAL TIME ULTRASOUND SCANNER; SPECKLE TRACKING ECHOCARDIOGRAPHY; STRAIN ECHOCARDIOGRAPHY; AGED; AMBULATORY ELECTROCARDIOGRAPHY; CARDIAC MUSCLE; CARDIOMYOPATHY, HYPERTROPHIC; CINE MAGNETIC RESONANCE IMAGING; COMORBIDITY; COMPARATIVE STUDY; COMPUTER ASSISTED DIAGNOSIS; DIAGNOSTIC IMAGING; DOPPLER ULTRASONOGRAPHY; FIBROSIS; KAPLAN MEIER METHOD; MULTIVARIATE ANALYSIS; PATHOLOGY; PATHOPHYSIOLOGY; PROGNOSIS; RECEIVER OPERATING CHARACTERISTIC; REFERENCE VALUE; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; SURVIVAL ANALYSIS; TACHYCARDIA, VENTRICULAR;

ADULT; AGED; CARDIOMYOPATHY, HYPERTROPHIC; COMORBIDITY; CROSS-SECTIONAL STUDIES; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY, AMBULATORY; FEMALE; FIBROSIS; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; KAPLAN-MEIER ESTIMATE; MAGNETIC RESONANCE IMAGING, CINE; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; MYOCARDIUM; PROGNOSIS; REFERENCE VALUES; RISK ASSESSMENT; ROC CURVE; SEVERITY OF ILLNESS INDEX; SURVIVAL ANALYSIS; TACHYCARDIA, VENTRICULAR; ULTRASONOGRAPHY, DOPPLER;

EID: 84979030647     PISSN: 20472404     EISSN: 20472412     Source Type: Journal    
DOI: 10.1093/ehjci/jew005     Document Type: Article

References (27)

1. Maron BJ. Contemporary insights and strategies for risk stratification and prevention of sudden death in hypertrophic cardiomyopathy. Circulation 2010;121: 445-56.
2. Elliott PM, Anastasakis A, Borger MA, Borggrefe M, Cecchi F, Charron P et al. 2014 ESC guidelines on diagnosis and management of hypertrophic cardiomyopathy: The task force for the diagnosis and management of hypertrophic cardiomyopathy of the European Society of Cardiology (ESC). Eur Heart J 2014;35:2733-79.
3. Members WC, Gersh BJ, Maron BJ, Bonow RO, Dearani JA, Fifer MA et al. 2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation 2011;124: e783-31.
4. Chan RH, Maron BJ, Olivotto I, Pencina MJ, Assenza GE, Haas T et al. Prognostic value of quantitative contrast-enhanced cardiovascular magnetic resonance for the evaluation of sudden death risk in patients with hypertrophic cardiomyopathy. Circulation 2014;130:484-95.
5. Rubinshtein R, Glockner JF, Ommen SR, Araoz PA, Ackerman MJ, Sorajja P et al. Characteristics and clinical significance of late gadolinium enhancement by contrast-enhanced magnetic resonance imaging in patients with hypertrophic cardiomyopathy. Circ Heart Fail 2010;3:51-8.
6. Cardim N, Galderisi M, Edvardsen T, Plein S, Popescu BA, DAndrea A et al. Role of multimodality cardiac imaging in the management of patients with hypertrophic cardiomyopathy: An expert consensus of the european association of cardiovascular imaging endorsed by the saudi heart association. Eur Heart J Cardiovasc Imaging 2015;16:280.
7. Saumarez RC, Camm AJ, Panagos A, Gill JS, Stewart JT, de Belder MA et al. Ventricular fibrillation in hypertrophic cardiomyopathy is associated with increased fractionation of paced right ventricular electrograms. Circulation 1992;86:467-74.
8. Edvardsen T. Quantitative assessment of intrinsic regional myocardial deformation by doppler strain rate echocardiography in humans: validation against threedimensional tagged magnetic resonance imaging. Circulation 2002;106:50-6.
9. Haugaa KH, Smedsrud MK, Steen T, Kongsgaard E, Loennechen JP, Skjaerpe T et al. Mechanical dispersion assessed by myocardial strain in patients after myocardial infarction for risk prediction of ventricular arrhythmia. JACC Cardiovasc Imaging 2010; 3:247-56.
10. Sarvari SI, Haugaa KH, Anfinsen OG, Leren TP, Smiseth OA, Kongsgaard E et al. Right ventricular mechanical dispersion is related to malignant arrhythmias: A study of patients with arrhythmogenic right ventricular cardiomyopathy and subclinical right ventricular dysfunction. Eur Heart J 2011;32:1089-96.
11. Haugaa KH, Hasselberg NE, Edvardsen T. Mechanical dispersion by strain echocardiography: A predictor of ventricular arrhythmias in subjects with lamin a/c mutations. JACC Cardiovasc Imaging 2015;8:104-6.
12. Pedersen CT, Kay GN, Kalman J, Borggrefe M, Della-Bella P, Dickfeld T et al. EHRA/HRS/APHRS expert consensus on ventricular arrhythmias. Europace 2014;16: 1257-83.
13. Afonso LC, Bernal J, Bax JJ, Abraham TP. Echocardiography in hypertrophic cardiomyopathy: The role of conventional and emerging technologies. JACC Cardiovasc Imaging 2008;1:787-800.
14. Nagueh SF, Appleton CP, Gillebert TC, Marino PN, Oh JK, Smiseth OA et al. Recommendations for the evaluation of left ventricular diastolic function by echocardiography. J Am Soc Echocardiogr 2009;22:107-33.
15. Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L et al. Recommendations for cardiac chamber quantification by echocardiography in adults: An update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr 2015;28:1-39. e14.
16. Cerqueira MD. Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart: A statement for healthcare professionals from the cardiac imaging committee of the council on clinical cardiology of the American Heart Association. Circulation 2002;105:539-42.
17. Haugaa KH, Amlie JP, Berge KE, Leren TP, Smiseth OA, Edvardsen T. Transmural differences in myocardial contraction in long-qt syndrome: mechanical consequences of ion channel dysfunction. Circulation 2010;122:1355-63.
18. Haugaa KH, Edvardsen T, Leren TP, Gran JM, Smiseth OA, Amlie JP. Left ventricular mechanical dispersion by tissue doppler imaging: A novel approach for identifying high-risk individuals with long qt syndrome. Eur Heart J 2009;30:330-7.
19. Heiberg E, Sjogren J, Ugander M, Carlsson M, Engblom H, Arheden H. Design and validation of segment-freely available software for cardiovascular image analysis. BMC Med Imaging 2010;10:1.
20. Almaas VM, Haugaa KH, Strom EH, Scott H, Smith HJ, Dahl CP et al. Noninvasive assessment of myocardial fibrosis in patients with obstructive hypertrophic cardiomyopathy. Heart 2014;100:631-8.
21. Almaas VM, Haugaa KH, Strom EH, Scott H, Dahl CP, Leren TP et al. Increased amount of interstitial fibrosis predicts ventricular arrhythmias, and is associated with reduced myocardial septal function in patients with obstructive hypertrophic cardiomyopathy. Europace 2013;15:1319-27.
22. Fluechter S, Kuschyk J, Wolpert C, Doesch C, Veltmann C, Haghi D et al. Extent of late gadolinium enhancement detected by cardiovascular magnetic resonance correlates with the inducibility of ventricular tachyarrhythmia in hypertrophic cardiomyopathy. J Cardiovasc Magn Reson 2010;12:30.
23. OHanlon R, Grasso A, Roughton M, Moon JC, Clark S, Wage R et al. Prognostic significance of myocardial fibrosis in hypertrophic cardiomyopathy. J Am Coll Cardiol 2010;56:867-74.
24. Maron MS, Appelbaum E, Harrigan CJ, Buros J, Gibson CM, Hanna C et al. Clinical profile and significance of delayed enhancement in hypertrophic cardiomyopathy. Circ Heart Fail 2008;1:184-91.
25. Ellims AH, Iles LM, Ling LH, Hare JL, Kaye DM, Taylor AJ. Diffuse myocardial fibrosis in hypertrophic cardiomyopathy can be identified by cardiovascular magnetic resonance, and is associated with left ventricular diastolic dysfunction. J Cardiovasc Magn Reson 2012;14:76.
26. Afonso L, Kondur A, Simegn M, Niraj A, Hari P, Kaur R et al. Two-dimensional strain profiles in patients with physiological and pathological hypertrophy and preserved left ventricular systolic function: A comparative analyses. BMJ Open 2012;2:e001390.
27. Monserrat L, Elliott PM, Gimeno JR, Sharma S, Penas-Lado M, McKenna WJ. Non-sustained ventricular tachycardia in hypertrophic cardiomyopathy: An independent marker of sudden death risk in young patients. J Am Coll Cardiol 2003;42: 873-9.