Right ventricular mechanical dispersion is related to malignant arrhythmias: A study of patients with arrhythmogenic right ventricular cardiomyopathy and subclinical right ventricular dysfunction

European Heart Journal

Volumn 32, Issue 9, 2011, Pages 1089-1096

  Sarvari, Sebastian I ^a,b   Haugaa, Kristina H ^a,b   Anfinsen, Ole Gunnar ^a   Leren, Trond P ^a   Smiseth, Otto A ^a,b   Kongsgaard, Erik ^a   Amlie, Jan P ^a,b   Edvardsen, Thor ^a,b  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

ARVC; Dispersion; Echocardiography; Myocardial contraction; Ventricular arrhythmia

Indexed keywords

ADULT; ARTICLE; CARDIOMYOPATHY; CONTROLLED STUDY; ELECTROCARDIOGRAPHY; FEMALE; HEART ARRHYTHMIA; HEART CONTRACTION; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE FUNCTION; HEART RIGHT VENTRICLE FAILURE; HEART RIGHT VENTRICLE FUNCTION; HUMAN; MAJOR CLINICAL STUDY; MALE; MECHANICS; MUTATION; PRIORITY JOURNAL; CASE CONTROL STUDY; GENETICS; HEART RIGHT VENTRICLE DYSPLASIA; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; HETEROZYGOTE; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGICAL STRESS; PHYSIOLOGY;

ADULT; ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA; CASE-CONTROL STUDIES; ELECTROCARDIOGRAPHY, AMBULATORY; FEMALE; HETEROZYGOTE; HUMANS; MALE; MIDDLE AGED; MUTATION; MYOCARDIAL CONTRACTION; STRESS, PHYSIOLOGICAL; TACHYCARDIA, VENTRICULAR; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR DYSFUNCTION, RIGHT; VENTRICULAR FIBRILLATION; YOUNG ADULT;

EID: 79958186248     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/ehr069     Document Type: Article

References (27)

1. Thiene G, Nava A, Corrado D, Rossi L, Pennelli N. Right ventricular cardiomyopathy and sudden death in young people. N Engl J Med 1988;318:129-133. (Pubitemid 18035134)
2. Sen-Chowdhry S, Morgan RD, Chambers JC, McKenna WJ. Arrhythmogenic cardiomyopathy: etiology, diagnosis, and treatment. Annu Rev Med 2010;61:233-253.
3. Manyari DE, Klein GJ, Gulamhusein S, Boughner D, Guiraudon GM, Wyse G, Mitchell LB, Kostuk WJ. Arrhythmogenic right ventricular dysplasia: a generalized cardiomyopathy? Circulation 1983;68:251-257. (Pubitemid 13028900)
4. Sen-Chowdhry S, Syrris P, Ward D, Asimaki A, Sevdalis E, McKenna WJ. Clinical and genetic characterization of families with arrhythmogenic right ventricular dysplasia/ cardiomyopathy provides novel insights into patterns of disease expression. Circulation 2007;115:1710-1720. (Pubitemid 46648607)
5. Vatta M, Marcus F, Towbin JA. Arrhythmogenic right ventricular cardiomyopathy: a 'final common pathway' that defines clinical phenotype. Eur Heart J 2007;28: 529-530. (Pubitemid 47355516)
6. Jain A, Shehata ML, Stuber M, Berkowitz SJ, Calkins H, Lima JA, Bluemke DA, Tandri H. Prevalence of left ventricular regional dysfunction in arrhythmogenic right ventricular dysplasia: a tagged MRI study. Circ Cardiovasc Imaging 2010;3: 290-297.
7. Xu T, Yang Z, Vatta M, Rampazzo A, Beffagna G, Pillichou K, Scherer SE, Saffitz J, Kravitz J, Zareba W, Danieli GA, Lorenzon A, Nava A, Bauce B, Thiene G, Basso C, Calkins H, Gear K, Marcus F, Towbin JA. Compound and digenic heterozygosity contributes to arrhythmogenic right ventricular cardiomyopathy. J Am Coll Cardiol 2010;55:587-597.
8. Dalal D, James C, Devanagondi R, Tichnell C, Tucker A, Prakasa K, Spevak PJ, Bluemke DA, Abraham T, Russell SD, Calkins H, Judge DP. Penetrance of mutations in plakophilin-2 among families with arrhythmogenic right ventricular dysplasia/cardiomyopathy. J Am Coll Cardiol 2006;48:1416-1424. (Pubitemid 44436806)
9. Saffitz JE. Dependence of electrical coupling on mechanical coupling in cardiac myocytes: insights gained from cardiomyopathies caused by defects in cell-cell connections. Ann N Y Acad Sci 2005;1047:336-344. (Pubitemid 41123852)
10. Saffitz JE. Arrhythmogenic cardiomyopathy and abnormalities of cell-to-cell coupling. Heart Rhythm 2009;6(Suppl. 8):S62-S65.
11. Marcus FI, McKenna WJ, Sherrill D, Basso C, Bauce B, Bluemke DA, Calkins H, Corrado D, Cox MG, Daubert JP, Fontaine G, Gear K, Hauer R, Nava A, Picard MH, Protonotarios N, Saffitz JE, Sanborn DM, Steinberg JS, Tandri H, Thiene G, Towbin JA, Tsatsopoulou A, Wichter T, Zareba W. Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia: proposed modification of the Task Force Criteria. Eur Heart J 2010;31:806-814.
12. Vartdal T, Brunvand H, Pettersen E, Smith HJ, Lyseggen E, Helle-Valle T, Skulstad H, Ihlen H, Edvardsen T. Early prediction of infarct size by strain Doppler echocardiography after coronary reperfusion. J Am Coll Cardiol 2007; 49:1715-1721. (Pubitemid 46589919)
13. Stanton T, Leano R, Marwick TH. Prediction of all-cause mortality from global longitudinal speckle strain: comparison with ejection fraction and wall motion scoring. Circ Cardiovasc Imaging 2009;2:356-364.
14. Teske AJ, Cox MG, De Boeck BW, Doevendans PA, Hauer RN, Cramer MJ. Echocardiographic tissue deformation imaging quantifies abnormal regional right ventricular function in arrhythmogenic right ventricular dysplasia/ cardiomyopathy. J Am Soc Echocardiogr 2009;22:920-927.
15. Amlie JP. Dispersion of repolarization. A basic electrophysiological mechanism behind malignant arrhythmias. Eur Heart J 1997;18:1200-1202. (Pubitemid 27332135)
16. Turrini P, Corrado D, Basso C, Nava A, Bauce B, Thiene G. Dispersion of ventricular depolarization-repolarization: a noninvasive marker for risk stratification in arrhythmogenic right ventricular cardiomyopathy. Circulation 2001;103: 3075-3080. (Pubitemid 32587854)
17. Haugaa KH, Edvardsen T, Leren TP, Gran JM, Smiseth OA, Amlie JP. Left ventricular mechanical dispersion by tissue Doppler imaging: a novel approach for identifying high-risk individuals with long QT syndrome. Eur Heart J 2009;30: 330-337.
18. Haugaa KH, Smedsrud MK, Steen T, Kongsgaard E, Loennechen JP, Skjaerpe T, Voigt J-U, Willems R, Smith G, Smiseth OA, Amlie JP, Edvardsen T. Mechanical dispersion assessed by myocardial strain in patients after myocardial infarction for risk prediction of ventricular arrhythmia. JACC Cardiovasc Imaging 2010;3: 247-256.
19. McKenna WJ, Thiene G, Nava A, Fontaliran F, Blomstrom-Lundqvist C, Fontaine G, Camerini F. Diagnosis of arrhythmogenic right ventricular dysplasia/ cardiomyopathy. Task Force of the Working Group Myocardial and Pericardial Disease of the European Society of Cardiology and of the Scientific Council on Cardiomyopathies of the International Society and Federation of Cardiology. Br Heart J 1994;71:215-218.
20. Sen-Chowdhry S, Syrris P, Prasad SK, Hughes SE, Merrifield R, Ward D, Pennell DJ, McKenna WJ. Left-dominant arrhythmogenic cardiomyopathy: an under-recognized clinical entity. J Am Coll Cardiol 2008;52:2175-2187.
21. Webb JG, Kerr CR, Huckell VF, Mizgala HF, Ricci DR. Left ventricular abnormalities in arrhythmogenic right ventricular dysplasia. Am J Cardiol 1986; 58:568-570. (Pubitemid 16052701)
22. Kjaergaard J, Svendsen JH, Sogaard P, Chen X, Bay NH, Kober L, Kjaer A, Hassager C. Advanced quantitative echocardiography in arrhythmogenic right ventricular cardiomyopathy. J Am Soc Echocardiogr 2007;20:27-35. (Pubitemid 46055294)
23. Tandri H, Calkins H, Nasir K, Bomma C, Castillo E, Rutberg J, Tichnell C, Lima JA, Bluemke DA. Magnetic resonance imaging findings in patients meeting task force criteria for arrhythmogenic right ventricular dysplasia. J Cardiovasc Electrophysiol 2003;14:476-482. (Pubitemid 36583907)
24. Sen-Chowdhry S, Prasad SK, Syrris P, Wage R, Ward D, Merrifield R, Smith GC, Firmin DN, Pennell DJ, McKenna WJ. Cardiovascular magnetic resonance in arrhythmogenic right ventricular cardiomyopathy revisited: comparison with task force criteria and genotype. J Am Coll Cardiol 2006;48:2132-2140. (Pubitemid 44738443)
25. Asimaki A, Tandri H, Huang H, Halushka MK, Gautam S, Basso C, Thiene G, Tsatsopoulou A, Protonotarios N, McKenna WJ, Calkins H, Saffitz JE. A new diagnostic test for arrhythmogenic right ventricular cardiomyopathy. N Engl J Med 2009;360:1075-1084.
26. Sen-Chowdhry S, Syrris P, McKenna WJ. Role of genetic analysis in the management of patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy. J Am Coll Cardiol 2007;50:1813-1821. (Pubitemid 350007965)
27. Dalal D, Nasir K, Bomma C, Prakasa K, Tandri H, Piccini J, Roguin A, Tichnell C, James C, Russell SD, Judge DP, Abraham T, Spevak PJ, Bluemke DA, Calkins H. Arrhythmogenic right ventricular dysplasia: a United States experience. Circulation 2005;112:3823-3832. (Pubitemid 43739479)