Fermentation of mixed substrates by Clostridium pasteurianum and its physiological, metabolic and proteomic characterizations

Microbial Cell Factories

Volumn 15, Issue 1, 2016, Pages

  Sabra, Wael ^a   Wang, Wei ^a   Surandram, Sruthi ^a   Groeger, Christin ^a   Zeng, An Ping ^a  

^a HAMBURG UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

1,3 propanediol; Butanol; Mixed substrate fermentation; Oxaloacetate; Pyruvate decarboxylation

Indexed keywords

BIOTIN; BIOTIN SYNTHASE; ENOLASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE (NADP); GLYCEROL; OXALOACETIC ACID; PYRUVATE CARBOXYLASE; PYRUVATE PHOSPHATE DIKINASE; 1,3-PROPANEDIOL; BACTERIAL PROTEIN; BUTANOL; GLUCOSE; PROPANEDIOL DERIVATIVE;

AMINO ACID SEQUENCE; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIUM CULTURE; CARBOXYLATION; CELL METABOLISM; CLOSTRIDIUM PASTEURIANUM; CONTROLLED STUDY; DECARBOXYLATION; ENZYME SYNTHESIS; FERMENTATION; GLYCOLYSIS; GROWTH RATE; METABOLIC ENGINEERING; METABOLOMICS; NONHUMAN; OXIDATIVE STRESS; PROCESS OPTIMIZATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEOMICS; CHEMISTRY; CLOSTRIDIUM; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM;

1-BUTANOL; BACTERIAL PROTEINS; CLOSTRIDIUM; FERMENTATION; GLUCOSE; PROPYLENE GLYCOLS; PROTEOMICS;

EID: 84979000373     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/s12934-016-0497-4     Document Type: Article

References (32)

1. Haus S, Jabbari S, Millat T, Janssen H, Fischer RJ, Bahl H, King JR, Wolkenhauer O. A systems biology approach to investigate the effect of pH-induced gene regulation on solvent production by Clostridium acetobutylicum in continuous culture. BMC Syst Biol. 2011;5:10.
2. Sillers R, Chow A, Tracy B, Papoutsakis ET. Metabolic engineering of the non-sporulating, non-solventogenic Clostridium acetobutylicum strain M5 to produce butanol without acetone demonstrate the robustness of the acid-formation pathways and the importance of the electron balance. Metab Eng. 2008;10:321-32.
3. Lehmann D, Radomski N, Lutke-Eversloh T. New insights into the butyric acid metabolism of Clostridium acetobutylicum. Appl Microbiol Biotechnol. 2012;96:1325-39.
4. Yadav S, Rawat G, Tripathi P, Saxena RK. Dual substrate strategy to enhance butanol production using high cell inoculum and its efficient recovery by pervaporation. Bioresour Technol. 2014;152:377-83.
5. Gonzalez-Penas H, Lu-Chau TA, Moreira MT, Lema JM. Solvent screening methodology for in situ ABE extractive fermentation. Appl Microbiol Biotechnol. 2014;98:5915-24.
6. Sabra W, Groeger C, Zeng AP. Microbial cell factories for diol production. Adv Biochem Eng Biotechnol. 2016;155:165-97.
7. Lee J, Jang YS, Choi SJ, Im JA, Song H, Cho JH, Seung DY, Papoutsakis ET, Bennett GN, Lee SY. Metabolic Engineering of Clostridium acetobutylicum ATCC 824 for Isopropanol-Butanol-Ethanol Fermentation. Appl Environ Microbiol. 2012;78:1416-23.
8. Zeng AP, Sabra W. Microbial production of diols as platform chemicals: recent progresses. Curr Opin Biotechnol. 2011;22:749-57.
9. Hüsemann MHW, Papoutsakis ET. SoIventogenesis in Clostridium Acetobutylicum fermentations related to carboxylic acid and proton concentrations. Biotechnol Bioeng. 1988;23:843-52.
10. Sabra W, Groeger C, Sharma PN, Zeng AP. Improved n-butanol production by a non-acetone producing Clostridium pasteurianum DSMZ 525 in mixed substrate fermentation. Appl Microbiol Biotechnol. 2014;98:4267-76.
11. Kao W-C, Lin D-S, Cheng C-L, Chen B-Y, Lin C-Y, Chang J-S. Enhancing butanol production with Clostridium pasteurianum CH4 using sequential glucose-glycerol addition and simultaneous dual-substrate cultivation strategies. Bioresour Technol. 2013;135:324-30.
12. Abbad-Andaloussi S, Amine J, Gerard P, Petitdemange H. Effect of glucose on glycerol metabolism by Clostridium butyricum DSM 5431. J Appl Microbiol. 1998;84:515-22.
13. Groeger C, Sabra W, Zeng A-P: Introduction to bioconversion and downstream processing: principles and process examples. In: Michele Aresta Adfd. de gruyter (editor). Biorefineries-an introduction. 1st ed. 2015;81-108.
14. Kolek J, Patakova P, Melzoch K, Sigler K, Rezanka T. Changes in Membrane Plasmalogens of Clostridium pasteurianum during butanol fermentation as determined by lipidomic analysis. PLoS One. 2015;10:e0122058.
15. Rappert S, Song L, Sabra W, Wang W, Zeng AP. Draft genome sequence of type strain Clostridium pasteurianum DSM 525 (ATCC 6013), a promising producer of chemicals and fuels. Genome Announc. 2013;1:e00232.
16. Benziman M, Eizen N. Pyruvate-phosphate dikinase and the control of gluconeogenesis in Acetobacter xylinum. J Biol Chem. 1971;246:57-61.
17. Reeves RE. A new enzyme with the glycolytic function of pyruvate kinase. J Biol Chem. 1968;243:3202-4.
18. Tjaden B, Plagens A, Dorr C, Siebers B, Hensel R. Phosphoenolpyruvate synthetase and pyruvate, phosphate dikinase of Thermoproteus tenax: key pieces in the puzzle of archaeal carbohydrate metabolism. Mol Microbiol. 2006;60:287-98.
19. Vercruysse M, Fauvart M, Beullens S, Braeken K, Cloots L, Engelen K, Marchal K, Michiels J. A comparative transcriptome analysis of Rhizobium etli bacteroids: specific gene expression during symbiotic nongrowth. Mol Plant Microbe Interact. 2011;24:1553-61.
20. Eichenberger P, Jensen ST, Conlon EM, van Ooij C, Silvaggi J, Gonzalez-Pastor JE, Fujita M, Ben-Yehuda S, Stragier P, Liu JS, et al. The sigmaE regulon and the identification of additional sporulation genes in Bacillus subtilis. J Mol Biol. 2003;327:945-72.
21. Fayet O, Ziegelhoffer T, Georgopoulos C. The groES and groEL heat shock gene products of Escherichia coli are essential for bacterial growth at all temperatures. J Bacteriol. 1989;171:1379-85.
22. Harvey RJ. Fraction of ribosomes synthesizing protein as a function of specific growth rate. J Bacteriol. 1973;114:287-93.
23. Schar J, Stoll R, Schauer K, Loeffler DI, Eylert E, Joseph B, Eisenreich W, Fuchs TM, Goebel W. Pyruvate carboxylase plays a crucial role in carbon metabolism of extra- and intracellularly replicating Listeria monocytogenes. J Bacteriol. 2010;192:1774-84.
24. Buckel W, Thauer RK. Energy conservation via electron bifurcating ferredoxin reduction and proton/Na(+) translocating ferredoxin oxidation. Biochim Biophys Acta. 2013;1827:94-113.
25. Tremblay PL, Zhang T, Dar SA, Leang C, Lovley DR. The Rnf complex of Clostridium ljungdahlii is a proton-translocating ferredoxin:NAD+ oxidoreductase essential for autotrophic growth. MBio. 2012;4:e00406-12.
26. Schneider DA, Gourse RL. Relationship between growth rate and ATP concentration in Escherichia coli: a bioassay for available cellular ATP. J Biol Chem. 2004;279:8262-8.
27. Vasconcelos I, Girbal L, Soucaille P. Regulation of carbon and electron flow in Clostridium acetobutylicum grown in chemostat culture at neutral pH on mixtures of glucose and glycerol. J Bacteriol. 1994;176:1443-50.
28. Venkataramanan KP, Kurniawan Y, Boatman JJ, Haynes CH, Taconi KA, Martin L, Bothun GD, Scholz C. Homeoviscous response of Clostridium pasteurianum to butanol toxicity during glycerol fermentation. J Biotechnol. 2014;179:8-14.
29. Biebl H. Fermentation of glycerol by Clostridium pasteurianum-batch and continuous culture studies. J Ind Microbiol Biotechnol. 2001;27:18-26.
30. Jensen TO, Kvist T, Mikkelsen MJ, Westermann P. Production of 1,3-PDO and butanol by a mutant strain of Clostridium pasteurianum with increased tolerance towards crude glycerol. AMB Express. 2012;2:44.
31. Bommareddy RR, Sabra W, Maheshwari G, Zeng AP. Metabolic network analysis and experimental study of lipid production in Rhodosporidium toruloides grown on single and mixed substrates. Microb Cell Fact. 2015;14:36.
32. Li J, Wang W, Wang Y, Zeng AP. Two-dimensional gel-based proteomic of the caries causative bacterium Streptococcus mutans UA159 and insight into the inhibitory effect of carolacton. Proteomics. 2013;13:3470-7.