BAX-BAK1-independent LC3B lipidation by BH3 mimetics is unrelated to BH3 mimetic activity and has only minimal effects on autophagic flux

Autophagy

Volumn 12, Issue 7, 2016, Pages 1083-1093

  Reljic, Boris ^a,b   Conos, Stephanie ^a,b   Lee, Erinna F ^a,b,c,d   Garnier, Jean Marc ^a,b   Dong, Li ^a,b   Lessene, Guillaume ^a,b   Fairlie, W Douglas ^a,b,c,d   Vaux, David L ^a,b   Lindqvist, Lisa M ^a,b  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c OLIVIA NEWTON JOHN CANCER RESEARCH INSTITUTE   (Australia)

^d LA TROBE UNIVERSITY   (Australia)

Author keywords

ABT 199; ABT 263; ABT 737; autophagy; BCL2; BECN1

Indexed keywords

BH3 PROTEIN; PEPTIDES AND PROTEINS; PROTEIN BAK1; PROTEIN BAX; PROTEIN LC3B; PROTEIN MAP1LC3B; UNCLASSIFIED DRUG; ABT-737; ANILINE DERIVATIVE; BAK1 PROTEIN, MOUSE; BAX PROTEIN, MOUSE; BIPHENYL DERIVATIVE; FUSED HETEROCYCLIC RINGS; MAP1LC3 PROTEIN, MOUSE; MICROTUBULE ASSOCIATED PROTEIN; NAVITOCLAX; NITROPHENOL; PIPERAZINE DERIVATIVE; PROTEIN BAK; PROTEIN BCL 2; SULFONAMIDE; VENETOCLAX;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOPHAGY; CHEMICAL REACTION; ENANTIOMER; LIPIDATION; MOUSE; NONHUMAN; ANIMAL; CELL CULTURE; DRUG EFFECTS; METABOLISM;

ANILINE COMPOUNDS; ANIMALS; APOPTOSIS; AUTOPHAGY; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; BIPHENYL COMPOUNDS; BRIDGED BICYCLO COMPOUNDS, HETEROCYCLIC; CELLS, CULTURED; MICE; MICROTUBULE-ASSOCIATED PROTEINS; NITROPHENOLS; PIPERAZINES; PROTO-ONCOGENE PROTEINS C-BCL-2; SULFONAMIDES;

EID: 84978967689     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.1080/15548627.2016.1179406     Document Type: Article

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