miR-30e blocks autophagy and acts synergistically with proanthocyanidin for inhibition of AVEN and BIRC6 to increase apoptosis in glioblastoma stem cells and glioblastoma SNB19 cells

PLoS ONE

Volumn 11, Issue 7, 2016, Pages

  Chakrabarti, Mrinmay ^a   Klionsky, Daniel J ^b   Ray, Swapan K ^a  

^a UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BECLIN 1; CALPAIN; CASPASE 3; CASPASE 8; CASPASE 9; ENZYME INHIBITOR; FODRIN; MESSENGER RNA; MICRORNA; MICRORNA 30E; PROANTHOCYANIDIN; PROTEIN AVEN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BIRC6; SODIUM SULFITE; UNCLASSIFIED DRUG; ACRIDINE ORANGE; ANTINEOPLASTIC AGENT; APOPTOSIS REGULATORY PROTEIN; AVEN PROTEIN, HUMAN; BIRC6 PROTEIN, HUMAN; INHIBITOR OF APOPTOSIS PROTEIN; MEMBRANE PROTEIN; MIRN30B MICRORNA, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SULFITE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CANCER STEM CELL; CELL VIABILITY; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG POTENTIATION; ENZYME ACTIVATION; GENETIC DATABASE; GENETIC TRANSFECTION; GLIOBLASTOMA CELL LINE; GLIOBLASTOMA STEM CELL; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; MONOTHERAPY; MTT ASSAY; PHARMACOGENETICS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SNB19 CELL LINE; UPREGULATION; BRAIN TUMOR; CHEMISTRY; GENE EXPRESSION PROFILING; GENETICS; GLIOBLASTOMA; HYPOXIA; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ACRIDINE ORANGE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BECLIN-1; BRAIN NEOPLASMS; CELL LINE, TUMOR; GENE EXPRESSION PROFILING; GLIOBLASTOMA; HUMANS; HYPOXIA; INHIBITOR OF APOPTOSIS PROTEINS; MEMBRANE PROTEINS; MICRORNAS; NEOPLASTIC STEM CELLS; PROANTHOCYANIDINS; SIGNAL TRANSDUCTION; SULFITES; TRANSFECTION;

EID: 84978766378     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0158537     Document Type: Article

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