Selective motor neuron resistance and recovery in a new inducible mouse model of TDP-43 proteinopathy

Journal of Neuroscience

Volumn 36, Issue 29, 2016, Pages 7707-7717

  Spiller, Krista J ^a   Cheung, Claudia J ^a   Restrepo, Clark R ^a   Kwong, Linda K ^a   Stieber, Anna M ^a   Trojanowski, John Q ^a   Lee, Virginia M Y ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Amyotrophic lateral sclerosis; Motor neuron; Reinnervation; RNLS mice; Selective vulnerability; TDP 43

Indexed keywords

ALCOHOL; CALCIUM CHLORIDE; CHOLERA TOXIN B SUBUNIT; EPOXY RESIN; FORMALDEHYDE; GELATINASE B; GLUTARALDEHYDE; MYOSIN HEAVY CHAIN; PARAFORMALDEHYDE; TOLONIUM CHLORIDE; TRANSACTIVATOR PROTEIN; URANYL ACETATE; CHOLERA TOXIN; DNA BINDING PROTEIN; NEUROFILAMENT PROTEIN; NEUROFILAMENT PROTEIN H; TDP-43 PROTEIN, HUMAN; VESICULAR ACETYLCHOLINE TRANSPORTER;

ADULT; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CONTROLLED STUDY; ELECTROPHYSIOLOGICAL ASSAY; FEMALE; GASTROCNEMIUS MUSCLE; HYPOGLOSSAL NUCLEUS; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; MOTONEURON; MOUSE; MUSCLE CONTRACTION; MUSCLE DENERVATION; NERVE CELL MEMBRANE CONDUCTANCE; NONHUMAN; PATHOLOGY; PRIORITY JOURNAL; REINNERVATION; SCIATIC NERVE; TDP 43 PROTEINOPATHY; TRANSGENE; ANIMAL; BRAIN STEM; CONVALESCENCE; ELECTRON MICROSCOPY; ELECTROSTIMULATION; GENE EXPRESSION REGULATION; GENETICS; HUMAN; INNERVATION; METABOLISM; MUTATION; PATHOPHYSIOLOGY; PHYSIOLOGY; SKELETAL MUSCLE; SPINAL CORD; TRANSGENIC MOUSE; ULTRASTRUCTURE;

ANIMALS; BRAIN STEM; CELL DEATH; CHOLERA TOXIN; DNA-BINDING PROTEINS; ELECTRIC STIMULATION; GENE EXPRESSION REGULATION; HUMANS; MATRIX METALLOPROTEINASE 9; MICE; MICE, TRANSGENIC; MICROSCOPY, ELECTRON; MOTOR NEURONS; MUSCLE, SKELETAL; MUTATION; NEUROFILAMENT PROTEINS; RECOVERY OF FUNCTION; SPINAL CORD; TDP-43 PROTEINOPATHIES; VESICULAR ACETYLCHOLINE TRANSPORT PROTEINS;

EID: 84978760325     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1457-16.2016     Document Type: Article

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