메뉴 건너뛰기




Volumn 25, Issue 3, 2016, Pages 332-338

From bench to bedside: Clinical implications of KRAS status in patients with colorectal liver metastasis

Author keywords

Colorectal liver metastasis; KRAS

Indexed keywords

K RAS PROTEIN; KRAS PROTEIN, HUMAN; PROTEIN P21;

EID: 84978758602     PISSN: 09607404     EISSN: 18793320     Source Type: Journal    
DOI: 10.1016/j.suronc.2016.07.002     Document Type: Review
Times cited : (22)

References (41)
  • 2
    • 84939251514 scopus 로고    scopus 로고
    • Meta-analysis of KRAS mutations and survival after resection of colorectal liver metastases
    • [2] Brudvik, K.W., Kopetz, S.E., Li, L., Conrad, C., Aloia, T.A., Vauthey, J.N., Meta-analysis of KRAS mutations and survival after resection of colorectal liver metastases. Br. J. Surg. 102:10 (2015), 1175–1183.
    • (2015) Br. J. Surg. , vol.102 , Issue.10 , pp. 1175-1183
    • Brudvik, K.W.1    Kopetz, S.E.2    Li, L.3    Conrad, C.4    Aloia, T.A.5    Vauthey, J.N.6
  • 3
    • 0034684620 scopus 로고    scopus 로고
    • Signal transduction and the Ets family of transcription factors
    • [3] Yordy, J.S., Muise-Helmericks, R.C., Signal transduction and the Ets family of transcription factors. Oncogene 19:55 (2000), 6503–6513.
    • (2000) Oncogene , vol.19 , Issue.55 , pp. 6503-6513
    • Yordy, J.S.1    Muise-Helmericks, R.C.2
  • 4
    • 0020315258 scopus 로고
    • Human genome contains four genes homologous to transforming genes of Harvey and Kirsten murine sarcoma viruses
    • [4] Chang, E.H., Gonda, M.A., Ellis, R.W., Scolnick, E.M., Lowy, D.R., Human genome contains four genes homologous to transforming genes of Harvey and Kirsten murine sarcoma viruses. Proc. Natl. Acad. Sci. U. S. A. 79:16 (1982), 4848–4852.
    • (1982) Proc. Natl. Acad. Sci. U. S. A. , vol.79 , Issue.16 , pp. 4848-4852
    • Chang, E.H.1    Gonda, M.A.2    Ellis, R.W.3    Scolnick, E.M.4    Lowy, D.R.5
  • 6
    • 84921270388 scopus 로고    scopus 로고
    • Targeting RAS-ERK signalling in cancer: promises and challenges, Nature reviews
    • [6] Samatar, A.A., Poulikakos, P.I., Targeting RAS-ERK signalling in cancer: promises and challenges, Nature reviews. Drug Discov. 13:12 (2014), 928–942.
    • (2014) Drug Discov. , vol.13 , Issue.12 , pp. 928-942
    • Samatar, A.A.1    Poulikakos, P.I.2
  • 7
    • 0020627846 scopus 로고
    • Hypomethylation of ras oncogenes in primary human cancers
    • [7] Feinberg, A.P., Vogelstein, B., Hypomethylation of ras oncogenes in primary human cancers. Biochem. Biophys. Res. Commun. 111:1 (1983), 47–54.
    • (1983) Biochem. Biophys. Res. Commun. , vol.111 , Issue.1 , pp. 47-54
    • Feinberg, A.P.1    Vogelstein, B.2
  • 9
    • 0026658820 scopus 로고
    • K-ras point mutations in human colorectal carcinomas: relation to aneuploidy and metastasis
    • [9] Suchy, B., Zietz, C., Rabes, H.M., K-ras point mutations in human colorectal carcinomas: relation to aneuploidy and metastasis. Int. J. Cancer 52:1 (1992), 30–33.
    • (1992) Int. J. Cancer , vol.52 , Issue.1 , pp. 30-33
    • Suchy, B.1    Zietz, C.2    Rabes, H.M.3
  • 12
    • 84884493477 scopus 로고    scopus 로고
    • RAS mutation status predicts survival and patterns of recurrence in patients undergoing hepatectomy for colorectal liver metastases
    • discussion 626–7
    • [12] Vauthey, J.N., Zimmitti, G., Kopetz, S.E., Shindoh, J., Chen, S.S., Andreou, A., Curley, S.A., Aloia, T.A., Maru, D.M., RAS mutation status predicts survival and patterns of recurrence in patients undergoing hepatectomy for colorectal liver metastases. Ann. Surg. 258:4 (2013), 619–626 discussion 626–7.
    • (2013) Ann. Surg. , vol.258 , Issue.4 , pp. 619-626
    • Vauthey, J.N.1    Zimmitti, G.2    Kopetz, S.E.3    Shindoh, J.4    Chen, S.S.5    Andreou, A.6    Curley, S.A.7    Aloia, T.A.8    Maru, D.M.9
  • 13
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • [13] Fearon, E.R., Vogelstein, B., A genetic model for colorectal tumorigenesis. Cell 61:5 (1990), 759–767.
    • (1990) Cell , vol.61 , Issue.5 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 14
    • 0028133436 scopus 로고
    • Prognostic factors of colorectal cancer: K-ras mutation, overexpression of the p53 protein, and cell proliferative activity
    • [14] Tanaka, M., Omura, K., Watanabe, Y., Oda, Y., Nakanishi, I., Prognostic factors of colorectal cancer: K-ras mutation, overexpression of the p53 protein, and cell proliferative activity. J. Surg. Oncol. 57:1 (1994), 57–64.
    • (1994) J. Surg. Oncol. , vol.57 , Issue.1 , pp. 57-64
    • Tanaka, M.1    Omura, K.2    Watanabe, Y.3    Oda, Y.4    Nakanishi, I.5
  • 15
    • 84867750349 scopus 로고    scopus 로고
    • KRAS mutation testing in metastatic colorectal cancer
    • [15] Tan, C., Du, X., KRAS mutation testing in metastatic colorectal cancer. World J. Gastroenterol 18:37 (2012), 5171–5180.
    • (2012) World J. Gastroenterol , vol.18 , Issue.37 , pp. 5171-5180
    • Tan, C.1    Du, X.2
  • 16
    • 84995790077 scopus 로고    scopus 로고
    • Impact of somatic mutations on patterns of metastasis in colorectal cancer
    • [16] Lipsyc, M., Yaeger, R., Impact of somatic mutations on patterns of metastasis in colorectal cancer. J. Gastrointest. Oncol. 6:6 (2015), 645–649.
    • (2015) J. Gastrointest. Oncol. , vol.6 , Issue.6 , pp. 645-649
    • Lipsyc, M.1    Yaeger, R.2
  • 17
    • 84938153807 scopus 로고    scopus 로고
    • KRAS status as an independent prognostic factor for survival after Yttrium-90 radioembolization therapy for unresectable colorectal Cancer liver metastases
    • [17] Lahti, S.J., Xing, M., Zhang, D., Lee, J.J., Magnetta, M.J., Kim, H.S., KRAS status as an independent prognostic factor for survival after Yttrium-90 radioembolization therapy for unresectable colorectal Cancer liver metastases. J. Vasc. Interven. Radiol. JVIR 26:8 (2015), 1102–1111.
    • (2015) J. Vasc. Interven. Radiol. JVIR , vol.26 , Issue.8 , pp. 1102-1111
    • Lahti, S.J.1    Xing, M.2    Zhang, D.3    Lee, J.J.4    Magnetta, M.J.5    Kim, H.S.6
  • 19
    • 73349114941 scopus 로고    scopus 로고
    • KRAS and BRAF mutations in advanced colorectal cancer are associated with poor prognosis but do not preclude benefit from oxaliplatin or irinotecan: results from the MRC FOCUS trial
    • [19] Richman, S.D., Seymour, M.T., Chambers, P., Elliott, F., Daly, C.L., Meade, A.M., Taylor, G., Barrett, J.H., Quirke, P., KRAS and BRAF mutations in advanced colorectal cancer are associated with poor prognosis but do not preclude benefit from oxaliplatin or irinotecan: results from the MRC FOCUS trial. J. Clin. Oncol. 27:35 (2009), 5931–5937.
    • (2009) J. Clin. Oncol. , vol.27 , Issue.35 , pp. 5931-5937
    • Richman, S.D.1    Seymour, M.T.2    Chambers, P.3    Elliott, F.4    Daly, C.L.5    Meade, A.M.6    Taylor, G.7    Barrett, J.H.8    Quirke, P.9
  • 20
    • 77149163487 scopus 로고    scopus 로고
    • KRAS mutation correlates with accelerated metastatic progression in patients with colorectal liver metastases
    • [20] Nash, G.M., Gimbel, M., Shia, J., Nathanson, D.R., Ndubuisi, M.I., Zeng, Z.S., Kemeny, N., Paty, P.B., KRAS mutation correlates with accelerated metastatic progression in patients with colorectal liver metastases. Ann. Surg. Oncol. 17:2 (2010), 572–578.
    • (2010) Ann. Surg. Oncol. , vol.17 , Issue.2 , pp. 572-578
    • Nash, G.M.1    Gimbel, M.2    Shia, J.3    Nathanson, D.R.4    Ndubuisi, M.I.5    Zeng, Z.S.6    Kemeny, N.7    Paty, P.B.8
  • 26
    • 84947127636 scopus 로고    scopus 로고
    • Effect of KRAS mutation on long-term outcomes of patients undergoing hepatic resection for colorectal liver metastases
    • [26] Margonis, G.A., Spolverato, G., Kim, Y., Karagkounis, G., Choti, M.A., Pawlik, T.M., Effect of KRAS mutation on long-term outcomes of patients undergoing hepatic resection for colorectal liver metastases. Ann. Surg. Oncol. 22:13 (2015), 4158–4165.
    • (2015) Ann. Surg. Oncol. , vol.22 , Issue.13 , pp. 4158-4165
    • Margonis, G.A.1    Spolverato, G.2    Kim, Y.3    Karagkounis, G.4    Choti, M.A.5    Pawlik, T.M.6
  • 29
    • 0033052966 scopus 로고    scopus 로고
    • Structural differences between valine-12 and aspartate-12 Ras proteins may modify carcinoma aggression
    • [29] Al-Mulla, F., Milner-White, E.J., Going, J.J., Birnie, G.D., Structural differences between valine-12 and aspartate-12 Ras proteins may modify carcinoma aggression. J. Pathaol. 187:4 (1999), 433–438.
    • (1999) J. Pathaol. , vol.187 , Issue.4 , pp. 433-438
    • Al-Mulla, F.1    Milner-White, E.J.2    Going, J.J.3    Birnie, G.D.4
  • 30
    • 0029132785 scopus 로고
    • Intrinsic and GTPase-activating protein-stimulated Ras GTPase assays
    • [30] Bollag, G., McCormick, F., Intrinsic and GTPase-activating protein-stimulated Ras GTPase assays. Methods Enzym. 255 (1995), 161–170.
    • (1995) Methods Enzym. , vol.255 , pp. 161-170
    • Bollag, G.1    McCormick, F.2
  • 31
    • 0034548712 scopus 로고    scopus 로고
    • K-ras codon 12 mutation induces higher level of resistance to apoptosis and predisposition to anchorage-independent growth than codon 13 mutation or proto-oncogene overexpression
    • [31] Guerrero, S., Casanova, I., Farre, L., Mazo, A., Capella, G., Mangues, R., K-ras codon 12 mutation induces higher level of resistance to apoptosis and predisposition to anchorage-independent growth than codon 13 mutation or proto-oncogene overexpression. Cancer Res. 60:23 (2000), 6750–6756.
    • (2000) Cancer Res. , vol.60 , Issue.23 , pp. 6750-6756
    • Guerrero, S.1    Casanova, I.2    Farre, L.3    Mazo, A.4    Capella, G.5    Mangues, R.6
  • 32
    • 0021126650 scopus 로고
    • Biological properties of human c-Ha-ras1 genes mutated at codon 12
    • [32] Seeburg, P.H., Colby, W.W., Capon, D.J., Goeddel, D.V., Levinson, A.D., Biological properties of human c-Ha-ras1 genes mutated at codon 12. Nature 312:5989 (1984), 71–75.
    • (1984) Nature , vol.312 , Issue.5989 , pp. 71-75
    • Seeburg, P.H.1    Colby, W.W.2    Capon, D.J.3    Goeddel, D.V.4    Levinson, A.D.5
  • 36
    • 84954531356 scopus 로고    scopus 로고
    • KRAS mutation status predicts site-specific recurrence and survival after resection of colorectal liver metastases irrespective of location of the primary lesion
    • [36] Shindoh, J., Nishioka, Y., Yoshioka, R., Sugawara, T., Sakamoto, Y., Hasegawa, K., Hashimoto, M., Kokudo, N., KRAS mutation status predicts site-specific recurrence and survival after resection of colorectal liver metastases irrespective of location of the primary lesion. Ann. Surg. Oncol., 2016.
    • (2016) Ann. Surg. Oncol.
    • Shindoh, J.1    Nishioka, Y.2    Yoshioka, R.3    Sugawara, T.4    Sakamoto, Y.5    Hasegawa, K.6    Hashimoto, M.7    Kokudo, N.8
  • 38
    • 84878634489 scopus 로고    scopus 로고
    • Prognostic significance of C-reactive protein polymorphism and KRAS/BRAF in synchronous liver metastasis from colorectal cancer
    • e65117
    • [38] Huang, C.J., Teng, H.W., Chien, C.C., Lin, J.K., Yang, S.H., Prognostic significance of C-reactive protein polymorphism and KRAS/BRAF in synchronous liver metastasis from colorectal cancer. PloS One, 8(6), 2014 e65117.
    • (2014) PloS One , vol.8 , Issue.6
    • Huang, C.J.1    Teng, H.W.2    Chien, C.C.3    Lin, J.K.4    Yang, S.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.