-
1
-
-
33845933757
-
Involvement of PI3K/PKG/ERK1/2 signaling pathways in cortical neurons to trigger protection by cotreatment of acetyl-L-carnitine and alpha-lipoic acid against HNE-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease
-
Abdul, H.M., Butterfield, D.A., Involvement of PI3K/PKG/ERK1/2 signaling pathways in cortical neurons to trigger protection by cotreatment of acetyl-L-carnitine and alpha-lipoic acid against HNE-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease. Free Radical Biol Med 42 (2007), 371–384.
-
(2007)
Free Radical Biol Med
, vol.42
, pp. 371-384
-
-
Abdul, H.M.1
Butterfield, D.A.2
-
3
-
-
0021024932
-
Carnitine–metabolism and functions
-
Bremer, J., Carnitine–metabolism and functions. Physiol Rev 63 (1983), 1420–1480.
-
(1983)
Physiol Rev
, vol.63
, pp. 1420-1480
-
-
Bremer, J.1
-
4
-
-
0035369623
-
Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway
-
Brunet, A., Datta, S.R., Greenberg, M.E., Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway. Curr Opin Neurobiol 11 (2001), 297–305.
-
(2001)
Curr Opin Neurobiol
, vol.11
, pp. 297-305
-
-
Brunet, A.1
Datta, S.R.2
Greenberg, M.E.3
-
5
-
-
0024371249
-
Uptake of acetyl-L-carnitine in the brain
-
Burlina, A.P., Sershen, H., Debler, E.A., Lajtha, A., Uptake of acetyl-L-carnitine in the brain. Neurochem Res 14 (1989), 489–493.
-
(1989)
Neurochem Res
, vol.14
, pp. 489-493
-
-
Burlina, A.P.1
Sershen, H.2
Debler, E.A.3
Lajtha, A.4
-
6
-
-
63049089317
-
Neuroprotective effects of acetyl-L-carnitine on neuropathic pain and apoptosis: a role for the nicotinic receptor
-
Di Cesare Mannelli, L., Ghelardini, C., Calvani, M., Nicolai, R., Mosconi, L., Toscano, A., Pacini, A., Bartolini, A., Neuroprotective effects of acetyl-L-carnitine on neuropathic pain and apoptosis: a role for the nicotinic receptor. J Neurosci Res 87 (2009), 200–207.
-
(2009)
J Neurosci Res
, vol.87
, pp. 200-207
-
-
Di Cesare Mannelli, L.1
Ghelardini, C.2
Calvani, M.3
Nicolai, R.4
Mosconi, L.5
Toscano, A.6
Pacini, A.7
Bartolini, A.8
-
7
-
-
73749085197
-
The neuropathy-protective agent acetyl-L-carnitine activates protein kinase C-gamma and MAPKs in a rat model of neuropathic pain
-
Di Cesare Mannelli, L., Ghelardini, C., Toscano, A., Pacini, A., Bartolini, A., The neuropathy-protective agent acetyl-L-carnitine activates protein kinase C-gamma and MAPKs in a rat model of neuropathic pain. Neuroscience 165 (2010), 1345–1352.
-
(2010)
Neuroscience
, vol.165
, pp. 1345-1352
-
-
Di Cesare Mannelli, L.1
Ghelardini, C.2
Toscano, A.3
Pacini, A.4
Bartolini, A.5
-
8
-
-
0346333096
-
Mechanisms of neuronal death and neuroprotection
-
Fiskum, G., Mechanisms of neuronal death and neuroprotection. J Neurosurg Anesthesiol 16 (2004), 108–110.
-
(2004)
J Neurosurg Anesthesiol
, vol.16
, pp. 108-110
-
-
Fiskum, G.1
-
9
-
-
0028814185
-
Effects of acetyl-L-carnitine treatment and stress exposure on the nerve growth factor receptor (p75NGFR) mRNA level in the central nervous system of aged rats
-
Foreman, P.J., Perez-Polo, J.R., Angelucci, L., Ramacci, M.T., Taglialatela, G., Effects of acetyl-L-carnitine treatment and stress exposure on the nerve growth factor receptor (p75NGFR) mRNA level in the central nervous system of aged rats. Prog Neuropsychopharmacol Biol Psychiatry 19 (1995), 117–133.
-
(1995)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.19
, pp. 117-133
-
-
Foreman, P.J.1
Perez-Polo, J.R.2
Angelucci, L.3
Ramacci, M.T.4
Taglialatela, G.5
-
10
-
-
80555125111
-
The cell biology of synaptic plasticity
-
Ho, V.M., Lee, J.A., Martin, K.C., The cell biology of synaptic plasticity. Science 334 (2011), 623–628.
-
(2011)
Science
, vol.334
, pp. 623-628
-
-
Ho, V.M.1
Lee, J.A.2
Martin, K.C.3
-
11
-
-
33745215607
-
Signalling mechanisms mediated by the phosphoinositide 3-kinase/Akt cascade in synaptic plasticity and memory in the rat
-
Horwood, J.M., Dufour, F., Laroche, S., Davis, S., Signalling mechanisms mediated by the phosphoinositide 3-kinase/Akt cascade in synaptic plasticity and memory in the rat. Eur J Neurosci 23 (2006), 3375–3384.
-
(2006)
Eur J Neurosci
, vol.23
, pp. 3375-3384
-
-
Horwood, J.M.1
Dufour, F.2
Laroche, S.3
Davis, S.4
-
12
-
-
71749085455
-
Acylcarnitines: role in brain
-
Jones, L.L., McDonald, D.A., Borum, P.R., Acylcarnitines: role in brain. Prog Lipid Res 49 (2010), 61–75.
-
(2010)
Prog Lipid Res
, vol.49
, pp. 61-75
-
-
Jones, L.L.1
McDonald, D.A.2
Borum, P.R.3
-
13
-
-
0020051129
-
Delayed neuronal death in the gerbil hippocampus following ischemia
-
Kirino, T., Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res 239 (1982), 57–69.
-
(1982)
Brain Res
, vol.239
, pp. 57-69
-
-
Kirino, T.1
-
14
-
-
84899049667
-
Acetyl-L-carnitine normalizes the impaired long-term potentiation and spine density in a rat model of global ischemia
-
Kocsis, K., Knapp, L., Gellert, L., Olah, G., Kis, Z., Takakuwa, H., Iwamori, N., Ono, E., Toldi, J., Farkas, T., Acetyl-L-carnitine normalizes the impaired long-term potentiation and spine density in a rat model of global ischemia. Neuroscience 269 (2014), 265–272.
-
(2014)
Neuroscience
, vol.269
, pp. 265-272
-
-
Kocsis, K.1
Knapp, L.2
Gellert, L.3
Olah, G.4
Kis, Z.5
Takakuwa, H.6
Iwamori, N.7
Ono, E.8
Toldi, J.9
Farkas, T.10
-
15
-
-
84930213160
-
Acetyl-L-carnitine and oxaloacetate in post-treatment against LTP impairment in a rat ischemia model. An in vitro electrophysiological study
-
Kocsis, K., Knapp, L., Meszaros, J., Kis, Z., Farkas, T., Vecsei, L., Toldi, J., Acetyl-L-carnitine and oxaloacetate in post-treatment against LTP impairment in a rat ischemia model. An in vitro electrophysiological study. J Neural Transm 122 (2015), 867–872.
-
(2015)
J Neural Transm
, vol.122
, pp. 867-872
-
-
Kocsis, K.1
Knapp, L.2
Meszaros, J.3
Kis, Z.4
Farkas, T.5
Vecsei, L.6
Toldi, J.7
-
16
-
-
84858077778
-
Carnitine derivatives: clinical usefulness
-
Malaguarnera, M., Carnitine derivatives: clinical usefulness. Curr Opin Gastroenterol 28 (2012), 166–176.
-
(2012)
Curr Opin Gastroenterol
, vol.28
, pp. 166-176
-
-
Malaguarnera, M.1
-
17
-
-
84925485588
-
Purine receptors are required for DHA-mediated neuroprotection against oxygen and glucose deprivation in hippocampal slices
-
Molz, S., Olescowicz, G., Kraus, J.R., Ludka, F.K., Tasca, C.I., Purine receptors are required for DHA-mediated neuroprotection against oxygen and glucose deprivation in hippocampal slices. Purinergic Signalling 11 (2015), 117–126.
-
(2015)
Purinergic Signalling
, vol.11
, pp. 117-126
-
-
Molz, S.1
Olescowicz, G.2
Kraus, J.R.3
Ludka, F.K.4
Tasca, C.I.5
-
18
-
-
40149087718
-
Neuroprotective effect of hydrogen peroxide on an in vitro model of brain ischaemia
-
Nistico, R., Piccirilli, S., Cucchiaroni, M.L., Armogida, M., Guatteo, E., Giampa, C., Fusco, F.R., Bernardi, G., Nistico, G., Mercuri, N.B., Neuroprotective effect of hydrogen peroxide on an in vitro model of brain ischaemia. Br J Pharmacol 153 (2008), 1022–1029.
-
(2008)
Br J Pharmacol
, vol.153
, pp. 1022-1029
-
-
Nistico, R.1
Piccirilli, S.2
Cucchiaroni, M.L.3
Armogida, M.4
Guatteo, E.5
Giampa, C.6
Fusco, F.R.7
Bernardi, G.8
Nistico, G.9
Mercuri, N.B.10
-
19
-
-
0033653231
-
Acetyl-L-carnitine physical-chemical, metabolic, and therapeutic properties: relevance for its mode of action in Alzheimer's disease and geriatric depression
-
Pettegrew, J.W., Levine, J., McClure, R.J., Acetyl-L-carnitine physical-chemical, metabolic, and therapeutic properties: relevance for its mode of action in Alzheimer's disease and geriatric depression. Mol Psychiatry 5 (2000), 616–632.
-
(2000)
Mol Psychiatry
, vol.5
, pp. 616-632
-
-
Pettegrew, J.W.1
Levine, J.2
McClure, R.J.3
-
20
-
-
33646899542
-
Acetyl-L-carnitine protects striatal neurons against in vitro ischemia: the role of endogenous acetylcholine
-
Picconi, B., Barone, I., Pisani, A., Nicolai, R., Benatti, P., Bernardi, G., Calvani, M., Calabresi, P., Acetyl-L-carnitine protects striatal neurons against in vitro ischemia: the role of endogenous acetylcholine. Neuropharmacology 50 (2006), 917–923.
-
(2006)
Neuropharmacology
, vol.50
, pp. 917-923
-
-
Picconi, B.1
Barone, I.2
Pisani, A.3
Nicolai, R.4
Benatti, P.5
Bernardi, G.6
Calvani, M.7
Calabresi, P.8
-
21
-
-
0020067965
-
Temporal profile of neuronal damage in a model of transient forebrain ischemia
-
Pulsinelli, W.A., Brierley, J.B., Plum, F., Temporal profile of neuronal damage in a model of transient forebrain ischemia. Ann Neurol 11 (1982), 491–498.
-
(1982)
Ann Neurol
, vol.11
, pp. 491-498
-
-
Pulsinelli, W.A.1
Brierley, J.B.2
Plum, F.3
-
22
-
-
0032723242
-
In vivo fatty acid incorporation into brain phospholipids in relation to signal transduction and membrane remodeling
-
Rapoport, S.I., In vivo fatty acid incorporation into brain phospholipids in relation to signal transduction and membrane remodeling. Neurochem Res 24 (1999), 1403–1415.
-
(1999)
Neurochem Res
, vol.24
, pp. 1403-1415
-
-
Rapoport, S.I.1
-
23
-
-
84878231468
-
Targeted drug delivery to treat pain and cerebral hypoxia
-
Ronaldson, P.T., Davis, T.P., Targeted drug delivery to treat pain and cerebral hypoxia. Pharmacol Rev 65 (2013), 291–314.
-
(2013)
Pharmacol Rev
, vol.65
, pp. 291-314
-
-
Ronaldson, P.T.1
Davis, T.P.2
-
24
-
-
84892392870
-
PI3K/Akt signal pathway involved in the cognitive impairment caused by chronic cerebral hypoperfusion in rats
-
Shu, Y., Zhang, H., Kang, T., Zhang, J.J., Yang, Y., Liu, H., Zhang, L., PI3K/Akt signal pathway involved in the cognitive impairment caused by chronic cerebral hypoperfusion in rats. PLoS One, 8, 2013, e81901.
-
(2013)
PLoS One
, vol.8
, pp. e81901
-
-
Shu, Y.1
Zhang, H.2
Kang, T.3
Zhang, J.J.4
Yang, Y.5
Liu, H.6
Zhang, L.7
-
25
-
-
0020423164
-
The distribution and role of carnitine in the mammalian brain
-
Shug, A.L., Schmidt, M.J., Golden, G.T., Fariello, R.G., The distribution and role of carnitine in the mammalian brain. Life Sci 31 (1982), 2869–2874.
-
(1982)
Life Sci
, vol.31
, pp. 2869-2874
-
-
Shug, A.L.1
Schmidt, M.J.2
Golden, G.T.3
Fariello, R.G.4
-
26
-
-
84863842930
-
Hypoxic–ischemic injury in the developing brain: the role of reactive oxygen species originating in mitochondria
-
Ten, V.S., Starkov, A., Hypoxic–ischemic injury in the developing brain: the role of reactive oxygen species originating in mitochondria. Neurol Res Int, 2012, 2012, 542976.
-
(2012)
Neurol Res Int
, vol.2012
, pp. 542976
-
-
Ten, V.S.1
Starkov, A.2
-
27
-
-
84907996983
-
Drug delivery to the ischemic brain
-
Thompson, B.J., Ronaldson, P.T., Drug delivery to the ischemic brain. Adv Pharmacol 71 (2014), 165–202.
-
(2014)
Adv Pharmacol
, vol.71
, pp. 165-202
-
-
Thompson, B.J.1
Ronaldson, P.T.2
-
28
-
-
84955216091
-
In vivo longitudinal proton magnetic resonance spectroscopy on neonatal hypoxic–ischemic rat brain injury: neuroprotective effects of acetyl-L-carnitine
-
Xu, S., Waddell, J., Zhu, W., Shi, D., Marshall, A.D., McKenna, M.C., Gullapalli, R.P., In vivo longitudinal proton magnetic resonance spectroscopy on neonatal hypoxic–ischemic rat brain injury: neuroprotective effects of acetyl-L-carnitine. Magn Reson Med 74 (2015), 1530–1542.
-
(2015)
Magn Reson Med
, vol.74
, pp. 1530-1542
-
-
Xu, S.1
Waddell, J.2
Zhu, W.3
Shi, D.4
Marshall, A.D.5
McKenna, M.C.6
Gullapalli, R.P.7
-
29
-
-
29744452133
-
Mechanisms of ischemic neuroprotection by acetyl-L-carnitine
-
Zanelli, S.A., Solenski, N.J., Rosenthal, R.E., Fiskum, G., Mechanisms of ischemic neuroprotection by acetyl-L-carnitine. Ann NY Acad Sci 1053 (2005), 153–161.
-
(2005)
Ann NY Acad Sci
, vol.1053
, pp. 153-161
-
-
Zanelli, S.A.1
Solenski, N.J.2
Rosenthal, R.E.3
Fiskum, G.4
-
30
-
-
83755186606
-
Acetyl-L-carnitine attenuates homocysteine-induced Alzheimer-like histopathological and behavioral abnormalities
-
Zhou, P., Chen, Z., Zhao, N., Liu, D., Guo, Z.Y., Tan, L., Hu, J., Wang, Q., Wang, J.Z., Zhu, L.Q., Acetyl-L-carnitine attenuates homocysteine-induced Alzheimer-like histopathological and behavioral abnormalities. Rejuvenation Res 14 (2011), 669–679.
-
(2011)
Rejuvenation Res
, vol.14
, pp. 669-679
-
-
Zhou, P.1
Chen, Z.2
Zhao, N.3
Liu, D.4
Guo, Z.Y.5
Tan, L.6
Hu, J.7
Wang, Q.8
Wang, J.Z.9
Zhu, L.Q.10
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