Phenylpyruvic acid-2-O-β-D-glucoside attenuates high glucose-induced apoptosis in H9c2 cardiomyocytes

Planta Medica

Volumn 82, Issue 17, 2016, Pages 1468-1474

  Dludla, Phiwayinkosi Vusi ^a,b   Muller, Christo John Frederick ^a   Joubert, Elizabeth ^c,d   Louw, Johan ^a   Gabuza, Kwazi Bethuel ^a   Huisamen, Barbara ^a,b   Essop, M Faadiel ^d   Johnson, Rabia ^a  

^a SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

^b UNIVERSITY OF STELLENBOSCH   (South Africa)

^c ARC INFRUITEC NIETVOORBIJ   (South Africa)

^d STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

Fatty acid uptake and oxidation; Hyperglycemia; Myocardial apoptosis; Phenylpyruvic acid 2 O D glucoside

Indexed keywords

CASPASE 3; CASPASE 7; GLUCOSE; GLUTATHIONE; METFORMIN; PHENYLPYRUVIC ACID; PHENYLPYRUVIC ACID 2 O BETA DEXTRO GLUCOSIDE; PLANT EXTRACT; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; 2-(GLUCOPYRANOSYLOXY)-3-PHENYLPROPENOIC ACID; ADENOSINE TRIPHOSPHATE; BAX PROTEIN, RAT; GLUCOSIDE; PHENYLPROPIONIC ACID DERIVATIVE;

ANIMAL CELL; APOPTOSIS; ARTICLE; ASPALATHUS; CARDIAC MUSCLE CELL; CELL PROTECTION; CONTROLLED STUDY; DRUG POTENTIATION; EMBRYO; FATTY ACID OXIDATION; FATTY ACID TRANSPORT; GLUCOTOXICITY; H9C2 CELL LINE; HYPERGLYCEMIA; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; TUNEL ASSAY; WESTERN BLOTTING; ANIMAL; CELL LINE; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; PATHOLOGY;

ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOSE; GLUCOSIDES; MEMBRANE POTENTIAL, MITOCHONDRIAL; METFORMIN; MYOCYTES, CARDIAC; PHENYLPROPIONATES; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; REACTIVE OXYGEN SPECIES;

EID: 84978529130     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0042-110856     Document Type: Article

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