Aspalathin and nothofagin from rooibos (Aspalathus linearis) inhibit endothelial protein C receptor shedding in vitro and in vivo

Fitoterapia

Volumn 100, Issue , 2015, Pages 179-186

  Kwak, Soyoung ^a   Han, Min Su ^b   Bae, Jong Sup ^a  

^a Kyungpook National University   (South Korea)

^b Daegu Fatima Hospital   (South Korea)

Author keywords

Aspalathin; EPCR shedding; Nothofagin; Vascular inflammation

Indexed keywords

ANTIINFLAMMATORY AGENT; ASPALATHIN; ENDOTHELIAL PROTEIN C RECEPTOR; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NOTHOFAGIN; PHORBOL 13 ACETATE 12 MYRISTATE; PLANT MEDICINAL PRODUCT; PROTEIN C; PROTHROMBIN; STRESS ACTIVATED PROTEIN KINASE; THROMBIN; THROMBOMODULIN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; UNCLASSIFIED DRUG; ACTIVATED PROTEIN C RECEPTOR; ADAM PROTEIN; BLOOD CLOTTING FACTOR; CELL SURFACE RECEPTOR; CHALCONE DERIVATIVE; TUMOR NECROSIS FACTOR-ALPHA CONVERTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; ASPALATHUS; ASPALATHUS LINEARIS; CELL SURFACE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SEPSIS; SURVIVAL; UMBILICAL VEIN ENDOTHELIAL CELL; ANIMAL; C57BL MOUSE; DRUG EFFECTS; METABOLISM; PHOSPHORYLATION;

ASPALATHUS LINEARIS; MUS;

ADAM PROTEINS; ANIMALS; ASPALATHUS; BLOOD COAGULATION FACTORS; CHALCONES; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTERLEUKIN-1BETA; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MICE, INBRED C57BL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RECEPTORS, CELL SURFACE; TETRADECANOYLPHORBOL ACETATE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84920475662     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2014.12.002     Document Type: Article

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