Mitochondrial DNA variants as genetic risk factors for Parkinson disease

European Journal of Neurology

Volumn 23, Issue 8, 2016, Pages 1289-1300

  Liou, C W ^a   Chuang, J H ^a   Chen, J B ^a   Tiao, M M ^a   Wang, P W ^a   Huang, S T ^a   Huang, T L ^a   Lee, W C ^a   Weng, S W ^a   Huang, P H ^a   Chen, S D ^a   Chen, R S ^b   Lu, C S ^b   Lin, T K ^a  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

cybrid; mitochondrial DNA; mitochondrial haplogroup; Parkinson disease; rotenone

Indexed keywords

GENOMIC DNA; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE; ROTENONE;

AGED; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL VIABILITY; CONFIDENCE INTERVAL; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIATION; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MITOCHONDRIAL HAPLOGROUP; MITOCHONDRIAL MEMBRANE POTENTIAL; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; NEXT GENERATION SEQUENCING; PARKINSON DISEASE; PRIORITY JOURNAL; RISK ASSESSMENT; SIMULATION;

EID: 84978511576     PISSN: 13515101     EISSN: 14681331     Source Type: Journal    
DOI: 10.1111/ene.13020     Document Type: Article

References (28)

1. Subramaniam SR, Chesselet MF. Mitochondrial dysfunction and oxidative stress in Parkinson's disease. Prog Neurobiol 2013; 106 – 107: 17–32.
2. Swerdlow RH, Parks JK, Miller SW, et al. Origin and functional consequences of the complex I defect in Parkinson's disease. Ann Neurol 1996; 40: 663–671.
3. Gu M, Cooper JM, Taanman JW, et al. Mitochondrial DNA transmission of the mitochondrial defect in Parkinson's disease. Ann Neurol 1998; 44: 177–186.
4. Suissa S, Wang Z, Poole J, et al. Ancient mtDNA genetic variants modulate mtDNA transcription and replication. PLoS Genet 2005; 5: e1000474.
5. Hudson G, Nalls M, Evans JR, et al. Two-stage association study and meta-analysis of mitochondrial DNA variants in Parkinson disease. Neurology 2013; 80: 2042–2048.
6. van der Walt JM, Nicodemus KK, Martin ER, et al. Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease. Am J Hum Genet 2003; 72: 804–811.
7. Chen CM, Kuan CC, Lee-Chen GJ, et al. Mitochondrial DNA polymorphisms and the risk of Parkinson's disease in Taiwan. J Neural Transm 2007; 114: 1017–1021.
8. Takasaki S. Mitochondrial haplogroups associated with Japanese centenarians, Alzheimer's patients, Parkinson's patients, type 2 diabetic patients and healthy non-obese young males. J Genet Genomics 2009; 36: 425–434.
9. Chen YF, Chen WJ, Lin XZ, et al. Mitochondrial DNA haplogroups and the risk of sporadic Parkinson's disease in Han Chinese. Chin Med J (Engl) 2015; 128: 1748–1754.
10. Taylor RW, Turnbull DM. Mitochondrial DNA mutations in human disease. Nat Rev Genet 2005; 6: 389–402.
11. Liou CW, Chen JB, Tiao MM, et al. Mitochondrial DNA coding and control region variants as genetic risk factors for type 2 diabetes. Diabetes 2012; 61: 2642–2651.
12. Itoh Y, Mizuki N, Shimada T, et al. High-throughput DNA typing of HLA-A, -B, -C, and -DRB1 loci by a PCR-SSOP-Luminex method in the Japanese population. Immunogenetics 2005; 57: 717–729.
13. Tanaka M, Cabrera VM, Gonzalez AM, et al. Mitochondrial genome variation in eastern Asia and the peopling of Japan. Genome Res 2004; 14: 1832–1850.
14. Yao YG, Kong QP, Bandelt HJ, et al. Phylogeographic differentiation of mitochondrial DNA in Han Chinese. Am J Hum Genet 2002; 70: 635–651.
15. Andrews RM, Kubacka I, Chinnery PF, et al. Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA. Nat Genet 1999; 23: 147.
16. Lin TK, Lin HY, Chen SD, et al. The creation of cybrids harboring mitochondrial haplogroups in the Taiwanese population of ethnic Chinese background: an extensive in vitro tool for the study of mitochondrial genomic variations. Oxid Med Cell Longev 2012; 2012: 824275.
17. Betarbet R, Sherer TB, MacKenzie G, et al. Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat Neurosci 2000; 3: 1301–1306.
18. Schapira AH, Cooper JM, Dexter D, et al. Mitochondrial complex I deficiency in Parkinson's disease. Lancet 1989; 1: 1269.
19. Perier C, Bovè J, Vila M, et al. The rotenone model of Parkinson's disease. Trends Neurosci 2003; 26: 345–346.
20. Finnilä S, Lehtonen MS, Majamaa K. Phylogenetic network for European mtDNA. Am J Hum Genet 2001; 68: 1475–1484.
21. Quintana-Murci L, Chaix R, Wells RS, et al. Where west meets east: the complex mtDNA landscape of the southwest and Central Asian corridor. Am J Hum Genet 2004; 74: 827–845.
22. van Oven M, Kayser M. Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation. Hum Mutat 2009; 30: E386–E394.
23. Tatsuta T, Langer T. Quality control of mitochondria: protection against neurodegeneration and ageing. EMBO J 2008; 27: 306–314.
24. Xiong N, Xiong J, Jia M, et al. The role of autophagy in Parkinson's disease: rotenone-based modeling. Behav Brain Funct 2013; 9: 13.
25. Kazuno A, Munskata K, Nagai T, et al. Identification of mitochondrial DNA polymorphisms that alter mitochondrial matrix pH and intracellular calcium dynamics. PLoS Genet 2006; 2: e128.
26. Niemi AK, Moilanen JS, Tanaka M, et al. A combination of three common inherited mitochondrial DNA polymorphisms promotes longevity in Finnish and Japanese subjects. Eur J Hum Genet 2005; 13: 166–170.
27. Canter JA, Kallianpur AR, Parl FF, et al. Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women. Cancer Res 2005; 65: 8028–8033.
28. McMahon FJ, Chen YS, Patel S, et al. Mitochondrial DNA sequence diversity in bipolar affective disorder. Am J Psychiatry 2000; 157: 1058–1064.