Suppression of autophagy impedes glioblastoma development and induces senescence

Autophagy

Volumn 12, Issue 9, 2016, Pages 1431-1439

  Gammoh, Noor ^a   Fraser, Jane ^a   Puente, Cindy ^b   Syred, Heather M ^a   Kang, Helen ^b   Ozawa, Tatsuya ^c   Lam, Du ^d   Acosta, Juan Carlos ^a   Finch, Andrew J ^a   Holland, Eric ^c   Jiang, Xuejun ^b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c USA   (United States)

^d CELGENE CORPORATION   (United States)

Author keywords

ATG7; autophagy; brain; cancer; glioblastoma; metabolism; RCAS; senescence; tumor

Indexed keywords

ATG13 ENZYME; ATG7 ENZYME; PROTEIN KINASE; PROTEIN KINASE ULK1; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; ATG13 PROTEIN, MOUSE; ATG7 PROTEIN, MOUSE; AUTOPHAGY RELATED PROTEIN 7; KRAS2 PROTEIN, MOUSE; PROTEIN P21; SERINE THREONINE PROTEIN KINASE ULK1; SMALL INTERFERING RNA; ULK1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CARCINOGENESIS; CELL AGING; CELL GROWTH; CONTROLLED STUDY; GLIA CELL; GLIOBLASTOMA; IN VITRO STUDY; MOUSE; NEWBORN; NONHUMAN; SIGNAL TRANSDUCTION; ANIMAL; BRAIN TUMOR; CELL TRANSFORMATION; CHICKEN; FIBROBLAST; GENETICS; GLIA; HYPOXIA; METABOLISM; PATHOLOGY; RNA INTERFERENCE; TUMOR CELL LINE;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; AUTOPHAGY-RELATED PROTEIN 7; AUTOPHAGY-RELATED PROTEIN-1 HOMOLOG; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; CELLULAR SENESCENCE; CHICKENS; FIBROBLASTS; GLIOBLASTOMA; HYPOXIA; MICE; NEUROGLIA; PROTO-ONCOGENE PROTEINS P21(RAS); RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84978488733     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.1080/15548627.2016.1190053     Document Type: Article

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