Comparison of biosensor platforms in the evaluation of high affinity antibody-antigen binding kinetics

Analytical Biochemistry

Volumn 508, Issue , 2016, Pages 78-96

  Yang, Danlin ^a   Singh, Ajit ^a,b   Wu, Helen ^a   Kroe Barrett, Rachel ^a  

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

^b Fu Foundation School of Engineering and Applied Science   (United States)

Author keywords

Antibody antigen interactions; Biacore; MX96; Octet; Optical biosensor; ProteOn

Indexed keywords

ANTIGEN-ANTIBODY REACTIONS; ANTIGENS; BENCHMARKING; DISSOCIATION; ECONOMIC AND SOCIAL EFFECTS; KINETICS; MONOCLONAL ANTIBODIES; RATE CONSTANTS;

ANTIBODY-ANTIGEN INTERACTIONS; BIACORE; MX96; OCTET; OPTICAL BIO-SENSORS; PROTEON;

BIOSENSORS;

MONOCLONAL ANTIBODY; PROPROTEIN CONVERTASE SUBSTILISIN KEXIN TYPE 9; SERINE PROTEINASE; UNCLASSIFIED DRUG; LIGAND; PROTEIN BINDING;

ANIMAL CELL; ANTIBODY AFFINITY; ANTIGEN BINDING; ARTICLE; ASSOCIATION RATE CONSTANT; BINDING AFFINITY; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; DEVICE COMPARISON; DISSOCIATION RATE CONSTANT; EVALUATION STUDY; FEMALE; HUMAN; HUMAN CELL; INTERNAL CONSISTENCY; MEASUREMENT ACCURACY; NONHUMAN; OPTICAL BIOSENSOR; PRIORITY JOURNAL; QUALITY CONTROL; RELIABILITY; REPRODUCIBILITY; COMPARATIVE STUDY; DEVICES; GENETIC PROCEDURES; KINETICS; METABOLISM; PHYSIOLOGY; STANDARDS;

ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; BIOSENSING TECHNIQUES; KINETICS; LIGANDS; PROTEIN BINDING; REPRODUCIBILITY OF RESULTS;

EID: 84978484334     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2016.06.024     Document Type: Article

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