Germline MC1R status influences somatic mutation burden in melanoma

Nature Communications

Volumn 7, Issue , 2016, Pages

  Robles Espinoza, Carla Daniela ^a,b   Roberts, Nicola D ^a   Chen, Shuyang ^c   Leacy, Finbarr P ^d,e   Alexandrov, Ludmil B ^a   Pornputtapong, Natapol ^f   Halaban, Ruth ^f   Krauthammer, Michael ^f   Cui, Rutao ^c   Timothy Bishop, D ^g   Adams, David J ^a  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b CENTRO DE FÍSICA APLICADA Y TECNOLOGÍA AVANZADA   (Mexico)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^f YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MELANOCORTIN 1 RECEPTOR;

ALLELE; GENE EXPRESSION; MUTATION; PROTEIN; RISK FACTOR;

ADULT; AGED; ALLELE; ARTICLE; CUTANEOUS MELANOMA; FEMALE; GERMLINE MUTATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MELANOCYTE; MELANOMA; MUCOSAL MELANOMA; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC MUTATION; SUN EXPOSURE; COHORT ANALYSIS; GENETIC PREDISPOSITION; GENETIC VARIATION; GENETICS; HAIR COLOR; HEAD AND NECK TUMOR; MELANOSIS; MIDDLE AGED; MUTATION; MUTATION ACCUMULATION; PATHOLOGY; SKIN PIGMENTATION; SKIN TUMOR; TUMOR INVASION;

AGED; ALLELES; COHORT STUDIES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GERM-LINE MUTATION; HAIR COLOR; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MELANOMA; MELANOSIS; MIDDLE AGED; MUTATION; MUTATION ACCUMULATION; NEOPLASM INVASIVENESS; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTOR, MELANOCORTIN, TYPE 1; SKIN NEOPLASMS; SKIN PIGMENTATION;

EID: 84978394444     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms12064     Document Type: Article

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