Peripheral Mechanosensory Neuron Dysfunction Underlies Tactile and Behavioral Deficits in Mouse Models of ASDs

Cell

Volumn 166, Issue 2, 2016, Pages 299-313

  Orefice, Lauren L ^a   Zimmerman, Amanda L ^a   Chirila, Anda M ^a   Sleboda, Steven J ^a   Head, Joshua P ^a   Ginty, David D ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR BETA3; CRE RECOMBINASE; FRAGILE X MENTAL RETARDATION PROTEIN; METHYL CPG BINDING PROTEIN 2; TRANSCRIPTION FACTOR CDX2; TRANSCRIPTION FACTOR EMX1; 4 AMINOBUTYRIC ACID A RECEPTOR; GABRB3 PROTEIN, MOUSE; MECP2 PROTEIN, MOUSE;

ADULT; AGGRESSION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY SPECIFICITY; ANXIETY; ARTICLE; AUTISM; BEHAVIOR DISORDER; COGNITION; CONTROLLED STUDY; FEMALE; GENE DELETION; GENE EXPRESSION; HETEROZYGOSITY; LETHALITY; MALE; MEMORY DISORDER; MISSENSE MUTATION; MOTOR DYSFUNCTION; MOUSE; NERVE CELL LESION; NONHUMAN; PRESYNAPTIC INHIBITION; PRIMARY AFFERENT DEPOLARIZATION; PRIORITY JOURNAL; SENSORY GATING; SENSORY NERVE CELL; SKIN SENSITIVITY; SOCIAL BEHAVIOR; SOCIAL DOMINANCE; SOCIAL INTERACTION; SPINAL CORD DORSAL HORN; STARTLE REFLEX; STOP CODON; SYNAPTIC TRANSMISSION; TACTILE DISCRIMINATION; TOUCH; ANIMAL; ANIMAL BEHAVIOR; DISEASE MODEL; GENETICS; HUMAN RELATION; METABOLISM; PATHOPHYSIOLOGY; SYNAPSE;

ANIMALS; AUTISM SPECTRUM DISORDER; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; INTERPERSONAL RELATIONS; METHYL-CPG-BINDING PROTEIN 2; MICE; RECEPTORS, GABA-A; SENSORY RECEPTOR CELLS; SPINAL CORD DORSAL HORN; SYNAPSES; TOUCH;

EID: 84978267016     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2016.05.033     Document Type: Article

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