메뉴 건너뛰기




Volumn 139, Issue 7, 2016, Pages 1608-1617

The prognostic significance of specific HOX gene expression patterns in ovarian cancer

Author keywords

HOX genes; ovarian cancer; prognosis; survival; targeted treatment

Indexed keywords

CISPLATIN; HOX PROTEIN; ONCOPROTEIN; PROTEIN PBX; UNCLASSIFIED DRUG;

EID: 84978204472     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.30204     Document Type: Article
Times cited : (55)

References (46)
  • 2
    • 0035909949 scopus 로고    scopus 로고
    • Aberrant expression of homeobox gene HOXA7 is associated with mullerian-like differentiation of epithelial ovarian tumors and the generation of a specific autologous antibody response
    • Naora H, Montz FJ, Chai CY, et al. Aberrant expression of homeobox gene HOXA7 is associated with mullerian-like differentiation of epithelial ovarian tumors and the generation of a specific autologous antibody response. Proc Natl Acad Sci USA 2001;98:15209–14.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 15209-15214
    • Naora, H.1    Montz, F.J.2    Chai, C.Y.3
  • 3
    • 18344373769 scopus 로고    scopus 로고
    • Lineage infidelity of epithelial ovarian cancers is controlled by HOX genes that specify regional identity in the reproductive tract
    • Cheng W, Liu J, Yoshida H, et al. Lineage infidelity of epithelial ovarian cancers is controlled by HOX genes that specify regional identity in the reproductive tract. Nat Med 2005;11:531–7.
    • (2005) Nat Med , vol.11 , pp. 531-537
    • Cheng, W.1    Liu, J.2    Yoshida, H.3
  • 4
    • 0030707708 scopus 로고    scopus 로고
    • A conserved Hox axis in the mouse and human female reproductive system: Late establishment and persistent adult expression of the Hoxa cluster genes
    • Taylor HS, VandenHeuvel GB, Igarashi P. A conserved Hox axis in the mouse and human female reproductive system: Late establishment and persistent adult expression of the Hoxa cluster genes. Biol Reprod 1997;57:1338–45.
    • (1997) Biol Reprod , vol.57 , pp. 1338-1345
    • Taylor, H.S.1    VandenHeuvel, G.B.2    Igarashi, P.3
  • 6
    • 0033731796 scopus 로고    scopus 로고
    • Altered HOX and WNT7A expression in human lung cancer
    • Calvo R, West J, Franklin W, et al. Altered HOX and WNT7A expression in human lung cancer. Proc Natl Acad Sci USA 2000;97:12776–81.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12776-12781
    • Calvo, R.1    West, J.2    Franklin, W.3
  • 7
    • 0141731286 scopus 로고    scopus 로고
    • Aberrant HOXC expression accompanies the malignant phenotype in human prostate
    • Miller GJ, Miller HL, van Bokhoven A, et al. Aberrant HOXC expression accompanies the malignant phenotype in human prostate. Cancer Res 2003;63:5879–88.
    • (2003) Cancer Res , vol.63 , pp. 5879-5888
    • Miller, G.J.1    Miller, H.L.2    van Bokhoven, A.3
  • 8
    • 0034702232 scopus 로고    scopus 로고
    • Compromised HOXA5 function can limit p53 expression in human breast tumours
    • Raman V, Martensen SA, Reisman D, et al. Compromised HOXA5 function can limit p53 expression in human breast tumours. Nature 2000;405:974–8.
    • (2000) Nature , vol.405 , pp. 974-978
    • Raman, V.1    Martensen, S.A.2    Reisman, D.3
  • 9
    • 0031587766 scopus 로고    scopus 로고
    • Human colorectal carcinogenesis is associated with deregulation of homeobox gene expression
    • Vider BZ, Zimber A, Hirsch D, et al. Human colorectal carcinogenesis is associated with deregulation of homeobox gene expression. Biochem Biophys Res Commun 1997;232:742–8.
    • (1997) Biochem Biophys Res Commun , vol.232 , pp. 742-748
    • Vider, B.Z.1    Zimber, A.2    Hirsch, D.3
  • 10
    • 79959838081 scopus 로고    scopus 로고
    • Integrated genomic analyses of ovarian carcinoma
    • Tcga Cgarn.Integrated genomic analyses of ovarian carcinoma. Nature 2011;474:609–15.
    • (2011) Nature , vol.474 , pp. 609-615
  • 11
    • 34250835880 scopus 로고    scopus 로고
    • Antagonism of HOX/PBX dimer formation blocks the in vivo proliferation of melanoma
    • Morgan R, Pirard PM, Shears L, et al. Antagonism of HOX/PBX dimer formation blocks the in vivo proliferation of melanoma. Cancer Res 2007;67:5806–13.
    • (2007) Cancer Res , vol.67 , pp. 5806-5813
    • Morgan, R.1    Pirard, P.M.2    Shears, L.3
  • 12
    • 59649099697 scopus 로고    scopus 로고
    • HOX transcription factors are potential therapeutic targets in non-small-cell lung cancer (targeting HOX genes in lung cancer)
    • Plowright L, Harrington KJ, Pandha HS, et al. HOX transcription factors are potential therapeutic targets in non-small-cell lung cancer (targeting HOX genes in lung cancer). Br J Cancer 2009;100:470–5.
    • (2009) Br J Cancer , vol.100 , pp. 470-475
    • Plowright, L.1    Harrington, K.J.2    Pandha, H.S.3
  • 13
    • 77951151837 scopus 로고    scopus 로고
    • Targeting HOX and PBX transcription factors in ovarian cancer
    • Morgan R, Plowright L, Harrington K, et al. Targeting HOX and PBX transcription factors in ovarian cancer. BMC Cancer 2010;10:89.
    • (2010) BMC Cancer , vol.10 , pp. 89
    • Morgan, R.1    Plowright, L.2    Harrington, K.3
  • 14
    • 53449098713 scopus 로고    scopus 로고
    • Disrupting the Interaction Between HOX and PBX Causes Necrotic and Apoptotic Cell Death in the Renal Cancer Lines CaKi-2 and 769-P
    • Shears L, Plowright L, Harrington K, et al. Disrupting the Interaction Between HOX and PBX Causes Necrotic and Apoptotic Cell Death in the Renal Cancer Lines CaKi-2 and 769-P. J Urol 2008;180:2196–201.
    • (2008) J Urol , vol.180 , pp. 2196-2201
    • Shears, L.1    Plowright, L.2    Harrington, K.3
  • 16
    • 84880291315 scopus 로고    scopus 로고
    • Evaluating cell lines as tumour models by comparison of genomic profiles
    • Domcke S, Sinha R, Levine DA, et al. Evaluating cell lines as tumour models by comparison of genomic profiles. Nat Commun 2013;4.
    • (2013) Nat Commun , vol.4
    • Domcke, S.1    Sinha, R.2    Levine, D.A.3
  • 17
    • 79959895071 scopus 로고    scopus 로고
    • HDAC4-Regulated STAT1 Activation Mediates Platinum Resistance in Ovarian Cancer
    • Stronach EA, Alfraidi A, Rama N, et al. HDAC4-Regulated STAT1 Activation Mediates Platinum Resistance in Ovarian Cancer. Cancer Res 2011;71:4412–22.
    • (2011) Cancer Res , vol.71 , pp. 4412-4422
    • Stronach, E.A.1    Alfraidi, A.2    Rama, N.3
  • 19
    • 33748794547 scopus 로고    scopus 로고
    • Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
    • Chou T-C. Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. Pharmacol Rev 2006;58:621–81.
    • (2006) Pharmacol Rev , vol.58 , pp. 621-681
    • Chou, T.-C.1
  • 21
    • 0023816378 scopus 로고
    • Characterization and Properties of Nine Human Ovarian Adenocarcinoma Cell Lines
    • Langdon SP, Lawrie SS, Hay FG, et al. Characterization and Properties of Nine Human Ovarian Adenocarcinoma Cell Lines. Cancer Res 1988;48:6166–72.
    • (1988) Cancer Res , vol.48 , pp. 6166-6172
    • Langdon, S.P.1    Lawrie, S.S.2    Hay, F.G.3
  • 22
    • 36048982511 scopus 로고    scopus 로고
    • MEIS and PBX homeobox proteins in ovarian cancer
    • Crijns APG, de Graeff P, Geerts D, et al. MEIS and PBX homeobox proteins in ovarian cancer. Eur J Cancer 2007;43:2495–505.
    • (2007) Eur J Cancer , vol.43 , pp. 2495-2505
    • Crijns, A.P.G.1    de Graeff, P.2    Geerts, D.3
  • 24
    • 38449107286 scopus 로고    scopus 로고
    • HOXA7 in epithelial ovarian cancer: Interrelationships between differentiation and clinical features
    • Ota T, Gilks CB, Longacre T, et al. HOXA7 in epithelial ovarian cancer: Interrelationships between differentiation and clinical features. Reprod Sci 2007;14:605–14.
    • (2007) Reprod Sci , vol.14 , pp. 605-614
    • Ota, T.1    Gilks, C.B.2    Longacre, T.3
  • 25
    • 33744727226 scopus 로고    scopus 로고
    • Suppression of invasive characteristics by antisense introduction of overexpressed HOX genes in ovarian cancer cells
    • Yamashita T, Tazawa S, Yawei Z, et al. Suppression of invasive characteristics by antisense introduction of overexpressed HOX genes in ovarian cancer cells. Int J Oncol 2006;28:931–8.
    • (2006) Int J Oncol , vol.28 , pp. 931-938
    • Yamashita, T.1    Tazawa, S.2    Yawei, Z.3
  • 26
    • 0035957399 scopus 로고    scopus 로고
    • A serologically identified tumor antigen encoded by a homeobox gene promotes growth of ovarian epithelial cells
    • Naora H, Yang Y, Montz FJ, et al. A serologically identified tumor antigen encoded by a homeobox gene promotes growth of ovarian epithelial cells. Proc Natl Acad Sci U S A 2001;98:4060–5.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 4060-4065
    • Naora, H.1    Yang, Y.2    Montz, F.J.3
  • 27
    • 33847713655 scopus 로고    scopus 로고
    • A role for the HOXB7 homeodomain protein in DNA repair
    • Rubin E, Wu XY, Zhu T, et al. A role for the HOXB7 homeodomain protein in DNA repair. Cancer Res 2007;67:1527–35.
    • (2007) Cancer Res , vol.67 , pp. 1527-1535
    • Rubin, E.1    Wu, X.Y.2    Zhu, T.3
  • 28
  • 29
    • 77953428228 scopus 로고    scopus 로고
    • Expression pattern of the class I homeobox genes in ovarian carcinoma
    • Hong JH, Lee JK, Park JJ, et al. Expression pattern of the class I homeobox genes in ovarian carcinoma. J Gynecol Oncol 2010;21:29–37.
    • (2010) J Gynecol Oncol , vol.21 , pp. 29-37
    • Hong, J.H.1    Lee, J.K.2    Park, J.J.3
  • 30
    • 0033794086 scopus 로고    scopus 로고
    • Immunocytochemical detection of the homeobox B3, B4, and C6 gene products in breast carcinomas
    • Bodey B, Siegel SE, Kaiser HE. Immunocytochemical detection of the homeobox B3, B4, and C6 gene products in breast carcinomas. Anticancer Res 2000;20:3281–6.
    • (2000) Anticancer Res , vol.20 , pp. 3281-3286
    • Bodey, B.1    Siegel, S.E.2    Kaiser, H.E.3
  • 31
    • 41849142699 scopus 로고    scopus 로고
    • High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector
    • Zhang XB, Beard BC, Trobridge GD, et al. High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector. J Clin Invest 2008;118:1502–10.
    • (2008) J Clin Invest , vol.118 , pp. 1502-1510
    • Zhang, X.B.1    Beard, B.C.2    Trobridge, G.D.3
  • 32
    • 0033860901 scopus 로고    scopus 로고
    • Immunocytochemical detection of homeobox B3, B4, and C6 gene product expression in lung carcinomas
    • Bodey B, Groger AM, Siegel SE, et al. Immunocytochemical detection of homeobox B3, B4, and C6 gene product expression in lung carcinomas. Anticancer Res 2000;20:2711–6.
    • (2000) Anticancer Res , vol.20 , pp. 2711-2716
    • Bodey, B.1    Groger, A.M.2    Siegel, S.E.3
  • 33
    • 79959838081 scopus 로고    scopus 로고
    • Integrated genomic analyses of ovarian carcinoma
    • Bell D, Berchuck A, Birrer M, et al. Integrated genomic analyses of ovarian carcinoma. Nature 2011;474:609–15.
    • (2011) Nature , vol.474 , pp. 609-615
    • Bell, D.1    Berchuck, A.2    Birrer, M.3
  • 34
    • 21344455343 scopus 로고    scopus 로고
    • Early developmental arrest of mammalian limbs lacking HoxA/HoxD gene function
    • Kmita M, Tarchini B, Zakany J, et al. Early developmental arrest of mammalian limbs lacking HoxA/HoxD gene function. Nature 2005;435:1113–6.
    • (2005) Nature , vol.435 , pp. 1113-1116
    • Kmita, M.1    Tarchini, B.2    Zakany, J.3
  • 35
    • 67449116605 scopus 로고    scopus 로고
    • HOXA13 promotes cancer cell growth and predicts poor survival of patients with esophageal squamous cell carcinoma
    • Gu Z-D, Shen L-Y, Wang H, et al. HOXA13 promotes cancer cell growth and predicts poor survival of patients with esophageal squamous cell carcinoma. Cancer Res 2009;69:4969–73.
    • (2009) Cancer Res , vol.69 , pp. 4969-4973
    • Gu, Z.-D.1    Shen, L.-Y.2    Wang, H.3
  • 36
    • 84876151759 scopus 로고    scopus 로고
    • Identification and validation that up-expression of HOXA13 is a novel independent prognostic marker of a worse outcome in gastric cancer based on immunohistochemistry
    • Han Y, Tu W-w, Wen Y-g, et al. Identification and validation that up-expression of HOXA13 is a novel independent prognostic marker of a worse outcome in gastric cancer based on immunohistochemistry. Med Oncol 2013;30:1–9.
    • (2013) Med Oncol , vol.30 , pp. 1-9
    • Han, Y.1    Tu, W.-W.2    Wen, Y.-G.3
  • 37
    • 80053337032 scopus 로고    scopus 로고
    • The HOX gene network in hepatocellular carcinoma
    • Cillo C, Schiavo G, Cantile M, et al. The HOX gene network in hepatocellular carcinoma. Int J Cancer 2011;129:2577–87.
    • (2011) Int J Cancer , vol.129 , pp. 2577-2587
    • Cillo, C.1    Schiavo, G.2    Cantile, M.3
  • 38
    • 0037430144 scopus 로고    scopus 로고
    • Serologic analysis of ovarian tumor antigens reveals a bias toward antigens encoded on 17q
    • Stone B, Schummer M, Paley PJ, et al. Serologic analysis of ovarian tumor antigens reveals a bias toward antigens encoded on 17q. Int J Cancer 2003;104:73–84.
    • (2003) Int J Cancer , vol.104 , pp. 73-84
    • Stone, B.1    Schummer, M.2    Paley, P.J.3
  • 39
    • 59449090734 scopus 로고    scopus 로고
    • The homeotic protein HOXC13 is a member of human DNA replication complexes
    • Comelli L, Marchetti L, Arosio D, et al. The homeotic protein HOXC13 is a member of human DNA replication complexes. Cell Cycle 2009;8:454–9.
    • (2009) Cell Cycle , vol.8 , pp. 454-459
    • Comelli, L.1    Marchetti, L.2    Arosio, D.3
  • 40
    • 84860812472 scopus 로고    scopus 로고
    • Increased HOX C13 expression in metastatic melanoma progression
    • Cantile M, Scognamiglio G, Anniciello A, et al. Increased HOX C13 expression in metastatic melanoma progression. J Transl Med 2012;10.
    • (2012) J Transl Med , vol.10
    • Cantile, M.1    Scognamiglio, G.2    Anniciello, A.3
  • 41
    • 0037224779 scopus 로고    scopus 로고
    • Fusion of the NUP98 gene and the homeobox gene HOXC13 in acute myeloid leukemia with t(11;12)(p15;q13)
    • Panagopoulos I, Isaksson M, Billstrom R, et al. Fusion of the NUP98 gene and the homeobox gene HOXC13 in acute myeloid leukemia with t(11;12)(p15;q13). Genes Chromosomes Cancer 2003;36:107.
    • (2003) Genes Chromosomes Cancer , vol.36 , pp. 107
    • Panagopoulos, I.1    Isaksson, M.2    Billstrom, R.3
  • 42
    • 0029656012 scopus 로고    scopus 로고
    • Up-Regulation of HOXC6, HOXD1, and HOXD8 Homeobox Gene Expression in Human Neuroblastoma Cells following Chemical Induction of Differentiation
    • Manohar CF, Salwen HR, Furtado MR, et al. Up-Regulation of HOXC6, HOXD1, and HOXD8 Homeobox Gene Expression in Human Neuroblastoma Cells following Chemical Induction of Differentiation. Tumor Biol 1996;17:34–47.
    • (1996) Tumor Biol , vol.17 , pp. 34-47
    • Manohar, C.F.1    Salwen, H.R.2    Furtado, M.R.3
  • 43
    • 23844473412 scopus 로고    scopus 로고
    • Aberrant expression of HOX genes in human invasive breast carcinoma
    • Makiyama K, Hamada JI, Takada M, et al. Aberrant expression of HOX genes in human invasive breast carcinoma. Oncol Rep 2005;13:673–9.
    • (2005) Oncol Rep , vol.13 , pp. 673-679
    • Makiyama, K.1    Hamada, J.I.2    Takada, M.3
  • 44
    • 33745070819 scopus 로고    scopus 로고
    • A subgroup of HOX Abd-B gene is differentially expressed in cervical cancer
    • Lopez R, Garrido E, Vazquez G, et al. A subgroup of HOX Abd-B gene is differentially expressed in cervical cancer. Int J Gynecol Cancer 2006;16:1289–96.
    • (2006) Int J Gynecol Cancer , vol.16 , pp. 1289-1296
    • Lopez, R.1    Garrido, E.2    Vazquez, G.3
  • 45
    • 14044266897 scopus 로고    scopus 로고
    • Altered expressions of HOX genes in human cutaneous malignant melanoma
    • Maeda K, Hamada J-I, Takahashi Y, et al. Altered expressions of HOX genes in human cutaneous malignant melanoma. Int J Cancer 2005;114:436–41.
    • (2005) Int J Cancer , vol.114 , pp. 436-441
    • Maeda, K.1    Hamada, J.-I.2    Takahashi, Y.3
  • 46
    • 68549135040 scopus 로고    scopus 로고
    • HOX D13 expression across 79 tumor tissue types
    • Cantile M, Franco R, Tschan A, et al. HOX D13 expression across 79 tumor tissue types. Int J Cancer 2009;125:1532–41.
    • (2009) Int J Cancer , vol.125 , pp. 1532-1541
    • Cantile, M.1    Franco, R.2    Tschan, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.