-
1
-
-
84896690513
-
Prevalence of childhood and adult obesity in the United States, 2011-2012
-
Ogden CL, Carroll MD, Kit BK, Flegal KM. Prevalence of childhood and adult obesity in the United States, 2011-2012. JAMA. 2014;311(8):806-14.
-
(2014)
JAMA
, vol.311
, Issue.8
, pp. 806-814
-
-
Ogden, C.L.1
Carroll, M.D.2
Kit, B.K.3
Flegal, K.M.4
-
2
-
-
2942657650
-
Medical consequences of obesity
-
Bray GA. Medical consequences of obesity. J Clin Endocrinol Metab. 2004;89(6):2583-9.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, Issue.6
, pp. 2583-2589
-
-
Bray, G.A.1
-
3
-
-
80052245888
-
Health and economic burden of the projected obesity trends in the USA and the UK
-
Wang YC, McPherson K, Marsh T, Gortmaker SL, Brown M. Health and economic burden of the projected obesity trends in the USA and the UK. Lancet. 2011;378(9793):815-25.
-
(2011)
Lancet
, vol.378
, Issue.9793
, pp. 815-825
-
-
Wang, Y.C.1
McPherson, K.2
Marsh, T.3
Gortmaker, S.L.4
Brown, M.5
-
4
-
-
0031908527
-
Multifactorial causation of obesity: implications for prevention
-
Grundy SM. Multifactorial causation of obesity: implications for prevention. Am J Clin Nutr. 1998;67(3):563S-72.
-
(1998)
Am J Clin Nutr
, vol.67
, Issue.3
, pp. 563S-572S
-
-
Grundy, S.M.1
-
5
-
-
0030843960
-
Genetic and environmental factors in relative body weight and human adiposity
-
Maes HH, Neale MC, Eaves LJ. Genetic and environmental factors in relative body weight and human adiposity. Behav Genet. 1997;27(4):325-51.
-
(1997)
Behav Genet
, vol.27
, Issue.4
, pp. 325-351
-
-
Maes, H.H.1
Neale, M.C.2
Eaves, L.J.3
-
6
-
-
84878502589
-
Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits
-
Zaitlen N, Kraft P, Patterson N, Pasaniuc B, Bhatia G, Pollack S, Price AL. Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits. PLoS Genet. 2013;9(5):e1003520.
-
(2013)
PLoS Genet
, vol.9
, Issue.5
-
-
Zaitlen, N.1
Kraft, P.2
Patterson, N.3
Pasaniuc, B.4
Bhatia, G.5
Pollack, S.6
Price, A.L.7
-
7
-
-
84862909349
-
Five years of GWAS discovery
-
Visscher PM, Brown MA, McCarthy MI, Yang J. Five years of GWAS discovery. Am J Hum Genet. 2012;90(1):7-24.
-
(2012)
Am J Hum Genet
, vol.90
, Issue.1
, pp. 7-24
-
-
Visscher, P.M.1
Brown, M.A.2
McCarthy, M.I.3
Yang, J.4
-
8
-
-
84923171580
-
Genetic studies of body mass index yield new insights for obesity biology
-
Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S, Buchkovich ML, Yang J. Genetic studies of body mass index yield new insights for obesity biology. Nature. 2015;518(7538):197-206.
-
(2015)
Nature
, vol.518
, Issue.7538
, pp. 197-206
-
-
Locke, A.E.1
Kahali, B.2
Berndt, S.I.3
Justice, A.E.4
Pers, T.H.5
Day, F.R.6
Powell, C.7
Vedantam, S.8
Buchkovich, M.L.9
Yang, J.10
-
9
-
-
58849088843
-
Missing heritability and GWAS utility
-
Bogardus C. Missing heritability and GWAS utility. Obesity. 2009;17(2):209-10.
-
(2009)
Obesity
, vol.17
, Issue.2
, pp. 209-210
-
-
Bogardus, C.1
-
10
-
-
84875669545
-
The genetics of human obesity
-
Xia Q, Grant SF. The genetics of human obesity. Ann N Y Acad Sci. 2013;1281(1):178-90.
-
(2013)
Ann N Y Acad Sci
, vol.1281
, Issue.1
, pp. 178-190
-
-
Xia, Q.1
Grant, S.F.2
-
11
-
-
34547227547
-
The obesity epidemic in the United States-gender, age, socioeconomic, racial/ethnic, and geographic characteristics: a systematic review and meta-regression analysis
-
Wang Y, Beydoun MA. The obesity epidemic in the United States-gender, age, socioeconomic, racial/ethnic, and geographic characteristics: a systematic review and meta-regression analysis. Epidemiol Rev. 2007;29(1):6-28.
-
(2007)
Epidemiol Rev
, vol.29
, Issue.1
, pp. 6-28
-
-
Wang, Y.1
Beydoun, M.A.2
-
12
-
-
85028126569
-
Genetic risk factors for BMI and obesity in an ethnically diverse population: results from the population architecture using genomics and epidemiology (PAGE) study
-
Fesinmeyer MD, North KE, Ritchie MD, Lim U, Franceschini N, Wilkens LR, Gross MD, Bůžková P, Glenn K, Quibrera PM. Genetic risk factors for BMI and obesity in an ethnically diverse population: results from the population architecture using genomics and epidemiology (PAGE) study. Obesity. 2013;21(4):835-46.
-
(2013)
Obesity
, vol.21
, Issue.4
, pp. 835-846
-
-
Fesinmeyer, M.D.1
North, K.E.2
Ritchie, M.D.3
Lim, U.4
Franceschini, N.5
Wilkens, L.R.6
Gross, M.D.7
Bůžková, P.8
Glenn, K.9
Quibrera, P.M.10
-
13
-
-
18444369013
-
The structure of haplotype blocks in the human genome
-
Gabriel SB, Schaffner SF, Nguyen H, Moore JM, Roy J, Blumenstiel B, Higgins J, DeFelice M, Lochner A, Faggart M. The structure of haplotype blocks in the human genome. Science. 2002;296(5576):2225-9.
-
(2002)
Science
, vol.296
, Issue.5576
, pp. 2225-2229
-
-
Gabriel, S.B.1
Schaffner, S.F.2
Nguyen, H.3
Moore, J.M.4
Roy, J.5
Blumenstiel, B.6
Higgins, J.7
DeFelice, M.8
Lochner, A.9
Faggart, M.10
-
14
-
-
0034016043
-
Profound obesity associated with a balanced translocation that disrupts the SIM1 gene
-
Holder JL, Butte NF, Zinn AR. Profound obesity associated with a balanced translocation that disrupts the SIM1 gene. Hum Mol Genet. 2000;9(1):101-8.
-
(2000)
Hum Mol Genet
, vol.9
, Issue.1
, pp. 101-108
-
-
Holder, J.L.1
Butte, N.F.2
Zinn, A.R.3
-
15
-
-
49449101079
-
The ADRB3 Trp64Arg variant and BMI: a meta-analysis of 44 833 individuals
-
Kurokawa N, Young EH, Oka Y, Satoh H, Wareham NJ, Sandhu M, Loos RJ. The ADRB3 Trp64Arg variant and BMI: a meta-analysis of 44 833 individuals. Int J Obes. 2008;32(8):1240-9.
-
(2008)
Int J Obes
, vol.32
, Issue.8
, pp. 1240-1249
-
-
Kurokawa, N.1
Young, E.H.2
Oka, Y.3
Satoh, H.4
Wareham, N.J.5
Sandhu, M.6
Loos, R.J.7
-
16
-
-
77956331627
-
Integrating common and rare genetic variation in diverse human populations
-
Consortium IH. Integrating common and rare genetic variation in diverse human populations. Nature. 2010;467(7311):52-8.
-
(2010)
Nature
, vol.467
, Issue.7311
, pp. 52-58
-
-
-
17
-
-
32544451924
-
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
-
Grant SF, Thorleifsson G, Reynisdottir I, Benediktsson R, Manolescu A, Sainz J, Helgason A, Stefansson H, Emilsson V, Helgadottir A. Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet. 2006;38(3):320-3.
-
(2006)
Nat Genet
, vol.38
, Issue.3
, pp. 320-323
-
-
Grant, S.F.1
Thorleifsson, G.2
Reynisdottir, I.3
Benediktsson, R.4
Manolescu, A.5
Sainz, J.6
Helgason, A.7
Stefansson, H.8
Emilsson, V.9
Helgadottir, A.10
-
18
-
-
34447340935
-
TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis
-
Cauchi S, El Achhab Y, Choquet H, Dina C, Krempler F, Weitgasser R, Nejjari C, Patsch W, Chikri M, Meyre D. TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis. J Mol Med. 2007;85(7):777-82.
-
(2007)
J Mol Med
, vol.85
, Issue.7
, pp. 777-782
-
-
Cauchi, S.1
Achhab, Y.2
Choquet, H.3
Dina, C.4
Krempler, F.5
Weitgasser, R.6
Nejjari, C.7
Patsch, W.8
Chikri, M.9
Meyre, D.10
-
19
-
-
84870502629
-
Bayesian refinement of association signals for 14 loci in 3 common diseases
-
Maller JB, McVean G, Byrnes J, Vukcevic D, Palin K, Su Z, Howson JM, Auton A, Myers S, Morris A. Bayesian refinement of association signals for 14 loci in 3 common diseases. Nat Genet. 2012;44(12):1294-301.
-
(2012)
Nat Genet
, vol.44
, Issue.12
, pp. 1294-1301
-
-
Maller, J.B.1
McVean, G.2
Byrnes, J.3
Vukcevic, D.4
Palin, K.5
Su, Z.6
Howson, J.M.7
Auton, A.8
Myers, S.9
Morris, A.10
-
20
-
-
34948819195
-
Variants of the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in an African-American population enriched for nephropathy
-
Sale MM, Smith SG, Mychaleckyj JC, Keene KL, Langefeld CD, Leak TS, Hicks PJ, Bowden DW, Rich SS, Freedman BI. Variants of the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in an African-American population enriched for nephropathy. Diabetes. 2007;56(10):2638-42.
-
(2007)
Diabetes
, vol.56
, Issue.10
, pp. 2638-2642
-
-
Sale, M.M.1
Smith, S.G.2
Mychaleckyj, J.C.3
Keene, K.L.4
Langefeld, C.D.5
Leak, T.S.6
Hicks, P.J.7
Bowden, D.W.8
Rich, S.S.9
Freedman, B.I.10
-
21
-
-
34247571415
-
Association of TCF7L2 polymorphisms with type 2 diabetes in Mexico City
-
Parra E, Cameron E, Simmonds L, Valladares A, McKeigue P, Shriver M, Wacher N, Kumate J, Kittles R, Cruz M. Association of TCF7L2 polymorphisms with type 2 diabetes in Mexico City. Clin Genet. 2007;71(4):359-66.
-
(2007)
Clin Genet
, vol.71
, Issue.4
, pp. 359-366
-
-
Parra, E.1
Cameron, E.2
Simmonds, L.3
Valladares, A.4
McKeigue, P.5
Shriver, M.6
Wacher, N.7
Kumate, J.8
Kittles, R.9
Cruz, M.10
-
22
-
-
84908509212
-
Redundant enhancers and causal variants in the TCF7L2 gene
-
Ruiz-Narváez EA. Redundant enhancers and causal variants in the TCF7L2 gene. Eur J Hum Genet. 2014;22:1243-6.
-
(2014)
Eur J Hum Genet
, vol.22
, pp. 1243-1246
-
-
Ruiz-Narváez, E.A.1
-
23
-
-
33845534950
-
TCF7L2 Variation Predicts Hyperglycemia Incidence in a French General Population The Data From an Epidemiological Study on the Insulin Resistance Syndrome (DESIR) Study
-
Cauchi S, Meyre D, Choquet H, Dina C, Born C, Marre M, Balkau B, Froguel P. TCF7L2 Variation Predicts Hyperglycemia Incidence in a French General Population The Data From an Epidemiological Study on the Insulin Resistance Syndrome (DESIR) Study. Diabetes. 2006;55(11):3189-92.
-
(2006)
Diabetes
, vol.55
, Issue.11
, pp. 3189-3192
-
-
Cauchi, S.1
Meyre, D.2
Choquet, H.3
Dina, C.4
Born, C.5
Marre, M.6
Balkau, B.7
Froguel, P.8
-
24
-
-
61449237995
-
TCF7L2 variants are associated with increased proinsulin/insulin ratios but not obesity traits in the Framingham Heart Study
-
Stolerman E, Manning A, McAteer J, Fox C, Dupuis J, Meigs J, Florez J. TCF7L2 variants are associated with increased proinsulin/insulin ratios but not obesity traits in the Framingham Heart Study. Diabetologia. 2009;52(4):614-20.
-
(2009)
Diabetologia
, vol.52
, Issue.4
, pp. 614-620
-
-
Stolerman, E.1
Manning, A.2
McAteer, J.3
Fox, C.4
Dupuis, J.5
Meigs, J.6
Florez, J.7
-
25
-
-
33750889376
-
Transcription Factor TCF7L2 Genetic Study in the French Population Expression in Human β-Cells and Adipose Tissue and Strong Association With Type 2 Diabetes
-
Cauchi S, Meyre D, Dina C, Choquet H, Samson C, Gallina S, Balkau B, Charpentier G, Pattou F, Stetsyuk V. Transcription Factor TCF7L2 Genetic Study in the French Population Expression in Human β-Cells and Adipose Tissue and Strong Association With Type 2 Diabetes. Diabetes. 2006;55(10):2903-8.
-
(2006)
Diabetes
, vol.55
, Issue.10
, pp. 2903-2908
-
-
Cauchi, S.1
Meyre, D.2
Dina, C.3
Choquet, H.4
Samson, C.5
Gallina, S.6
Balkau, B.7
Charpentier, G.8
Pattou, F.9
Stetsyuk, V.10
-
26
-
-
84920617544
-
The brown fat-enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuation of hepatic lipogenesis
-
Wang GX, Zhao XY, Meng ZX, Kern M, Dietrich A, Chen Z, Cozacov Z, Zhou D, Okunade AL, Su X, et al. The brown fat-enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuation of hepatic lipogenesis. Nat Med. 2014;20(12):1436-43.
-
(2014)
Nat Med
, vol.20
, Issue.12
, pp. 1436-1443
-
-
Wang, G.X.1
Zhao, X.Y.2
Meng, Z.X.3
Kern, M.4
Dietrich, A.5
Chen, Z.6
Cozacov, Z.7
Zhou, D.8
Okunade, A.L.9
Su, X.10
-
27
-
-
0036827577
-
ErbB signaling regulates lineage determination of developing pancreatic islet cells in embryonic organ culture
-
Huotari MA, Miettinen PJ, Palgi J, Koivisto T, Ustinov J, Harari D, Yarden Y, Otonkoski T. ErbB signaling regulates lineage determination of developing pancreatic islet cells in embryonic organ culture. Endocrinology. 2002;143(11):4437-46.
-
(2002)
Endocrinology
, vol.143
, Issue.11
, pp. 4437-4446
-
-
Huotari, M.A.1
Miettinen, P.J.2
Palgi, J.3
Koivisto, T.4
Ustinov, J.5
Harari, D.6
Yarden, Y.7
Otonkoski, T.8
-
28
-
-
0034038355
-
Expression of ErbB receptors during pancreatic islet development and regrowth
-
Kritzik MR, Krahl T, Good A, Gu D, Lai C, Fox H, Sarvetnick N. Expression of ErbB receptors during pancreatic islet development and regrowth. J Endocrinol. 2000;165(1):67-77.
-
(2000)
J Endocrinol
, vol.165
, Issue.1
, pp. 67-77
-
-
Kritzik, M.R.1
Krahl, T.2
Good, A.3
Gu, D.4
Lai, C.5
Fox, H.6
Sarvetnick, N.7
-
29
-
-
33845534764
-
Downregulation of EGF receptor signaling in pancreatic islets causes diabetes due to impaired postnatal beta-cell growth
-
Miettinen PJ, Ustinov J, Ormio P, Gao R, Palgi J, Hakonen E, Juntti-Berggren L, Berggren PO, Otonkoski T. Downregulation of EGF receptor signaling in pancreatic islets causes diabetes due to impaired postnatal beta-cell growth. Diabetes. 2006;55(12):3299-308.
-
(2006)
Diabetes
, vol.55
, Issue.12
, pp. 3299-3308
-
-
Miettinen, P.J.1
Ustinov, J.2
Ormio, P.3
Gao, R.4
Palgi, J.5
Hakonen, E.6
Juntti-Berggren, L.7
Berggren, P.O.8
Otonkoski, T.9
-
30
-
-
79960700796
-
Next generation genome-wide association tool: design and coverage of a high-throughput European-optimized SNP array
-
Hoffmann TJ, Kvale MN, Hesselson SE, Zhan Y, Aquino C, Cao Y, Cawley S, Chung E, Connell S, Eshragh J. Next generation genome-wide association tool: design and coverage of a high-throughput European-optimized SNP array. Genomics. 2011;98(2):79-89.
-
(2011)
Genomics
, vol.98
, Issue.2
, pp. 79-89
-
-
Hoffmann, T.J.1
Kvale, M.N.2
Hesselson, S.E.3
Zhan, Y.4
Aquino, C.5
Cao, Y.6
Cawley, S.7
Chung, E.8
Connell, S.9
Eshragh, J.10
-
31
-
-
0036840537
-
Multi-ethnic study of atherosclerosis: objectives and design
-
Bild DE, Bluemke DA, Burke GL, Detrano R, Roux AVD, Folsom AR, Greenland P, JacobsJr DR, Kronmal R, Liu K. Multi-ethnic study of atherosclerosis: objectives and design. Am J Epidemiol. 2002;156(9):871-81.
-
(2002)
Am J Epidemiol
, vol.156
, Issue.9
, pp. 871-881
-
-
Bild, D.E.1
Bluemke, D.A.2
Burke, G.L.3
Detrano, R.4
Roux, A.V.D.5
Folsom, A.R.6
Greenland, P.7
JacobsJr, D.R.8
Kronmal, R.9
Liu, K.10
-
32
-
-
33746512512
-
Principal components analysis corrects for stratification in genome-wide association studies
-
Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet. 2006;38(8):904-9.
-
(2006)
Nat Genet
, vol.38
, Issue.8
, pp. 904-909
-
-
Price, A.L.1
Patterson, N.J.2
Plenge, R.M.3
Weinblatt, M.E.4
Shadick, N.A.5
Reich, D.6
-
33
-
-
34548292504
-
PLINK: a tool set for whole-genome association and population-based linkage analyses
-
Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, Bender D, Maller J, Sklar P, De Bakker PI, Daly MJ. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet. 2007;81(3):559-75.
-
(2007)
Am J Hum Genet
, vol.81
, Issue.3
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
Thomas, L.4
Ferreira, M.A.5
Bender, D.6
Maller, J.7
Sklar, P.8
Bakker, P.I.9
Daly, M.J.10
-
34
-
-
84883147479
-
Genome-wide association study of pre-eclampsia detects novel maternal single nucleotide polymorphisms and copy-number variants in subsets of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study cohort
-
Zhao L, Bracken MB, DeWan AT. Genome-wide association study of pre-eclampsia detects novel maternal single nucleotide polymorphisms and copy-number variants in subsets of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study cohort. Ann Hum Genet. 2013;77(4):277-87.
-
(2013)
Ann Hum Genet
, vol.77
, Issue.4
, pp. 277-287
-
-
Zhao, L.1
Bracken, M.B.2
DeWan, A.T.3
-
35
-
-
0037098199
-
Quantifying heterogeneity in a meta-analysis
-
Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21(11):1539-58.
-
(2002)
Stat Med
, vol.21
, Issue.11
, pp. 1539-1558
-
-
Higgins, J.P.1
Thompson, S.G.2
-
36
-
-
0041876133
-
Measuring inconsistency in meta-analyses
-
Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327(7414):557.
-
(2003)
BMJ
, vol.327
, Issue.7414
, pp. 557
-
-
Higgins, J.P.1
Thompson, S.G.2
Deeks, J.J.3
Altman, D.G.4
-
37
-
-
6844255857
-
Design of the Women's Health Initiative Clinical Trial and Observational Study-examples from the Women's Health Initiative
-
WHI-Study-Group. Design of the Women's Health Initiative Clinical Trial and Observational Study-examples from the Women's Health Initiative. Control Clin Trials. 1998;19(1):61-109.
-
(1998)
Control Clin Trials
, vol.19
, Issue.1
, pp. 61-109
-
-
|