Meganuclease-Mediated COL7A1 Gene Correction for Recessive Dystrophic Epidermolysis Bullosa

Journal of Investigative Dermatology

Volumn 136, Issue 4, 2016, Pages 872-875

  Izmiryan, Araksya ^a,b   Danos, Olivier ^c   Hovnanian, Alain ^a,b,d  

^a IMAGINE INSTITUTE   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c BIOGEN   (United States)

^d HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN 7 A1; COLLAGEN TYPE 7; LENTIVIRUS VECTOR; MEGANUCLEASE; NUCLEASE; UNCLASSIFIED DRUG; COL7A1 PROTEIN, HUMAN; DEOXYRIBONUCLEASE;

ARTICLE; DENSITOMETRY; DNA CLEAVAGE; EPIDERMOLYSIS BULLOSA DYSTROPHICA; EXON; FIBROBLAST; GENE EXPRESSION; GENE MUTATION; HUMAN; IMMUNOHISTOCHEMISTRY; INDUCED PLURIPOTENT STEM CELL; INTRON; KERATINOCYTE; PRIORITY JOURNAL; PROMOTER REGION; RECESSIVE DYSTROPHIC EPIDERMOLYSIS BULLOSA; WESTERN BLOTTING; DNA REPAIR; DOMINANT GENE; DOUBLE STRANDED DNA BREAK; FLUORESCENCE MICROSCOPY; GENE VECTOR; GENETICS; HEK293 CELL LINE; LENTIVIRINAE; METABOLISM; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE; RECESSIVE GENE; SEQUENCE HOMOLOGY;

BASE SEQUENCE; COLLAGEN TYPE VII; DEOXYRIBONUCLEASES; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; EPIDERMOLYSIS BULLOSA DYSTROPHICA; EXONS; FIBROBLASTS; GENES, DOMINANT; GENES, RECESSIVE; GENETIC VECTORS; HEK293 CELLS; HUMANS; INTRONS; KERATINOCYTES; LENTIVIRUS; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; MUTATION; SEQUENCE HOMOLOGY, NUCLEIC ACID;

EID: 84978043332     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1016/j.jid.2015.11.028     Document Type: Article

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