Sonothrombolysis with BR38 microbubbles improves microvascular patency in a rat model of stroke

PLoS ONE

Volumn 11, Issue 4, 2016, Pages

  Schleicher, Nadine ^a,b   Tomkins, Amelia J ^a,c   Kampschulte, Marian ^a   Hyvelin, Jean Marc ^d   Botteron, Catherine ^d   Juenemann, Martin ^a   Yeniguen, Mesut ^a   Krombach, Gabriele A ^a   Kaps, Manfred ^a   Spratt, Neil J ^c,e   Gerriets, Tibo ^a,e   Nedelmann, Max ^f,g  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b KERCKHOFF HEART CENTER   (Germany)

^c UNIVERSITY OF NEWCASTLE   (Australia)

^d Bracco Suisse SA   (Switzerland)

^e Hunter New England Local Health District ^*  (Germany)

^f SANA KLINIKUM OFFENBACH   (Germany)

^g UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALTEPLASE; BR 38; DIAGNOSTIC AGENT; SONOVUE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD CLOT LYSIS; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; HEMISPHERE; MALE; MICRO-COMPUTED TOMOGRAPHY; MICROBUBBLE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; RANDOMIZED CONTROLLED TRIAL; RAT; RAT MODEL; SONOTHROMBOLYSIS; TREATMENT DURATION; ULTRASOUND; VASCULAR PATENCY; WISTAR RAT; ANIMAL; DIAGNOSTIC IMAGING; DISEASE MODEL; ECHOGRAPHY; FIBRINOLYTIC THERAPY; NANOTECHNOLOGY; PROCEDURES; STROKE; THERAPEUTIC USE;

ANIMALS; DISEASE MODELS, ANIMAL; MALE; MICROBUBBLES; NANOTECHNOLOGY; RATS; RATS, WISTAR; STROKE; THROMBOLYTIC THERAPY; ULTRASONIC WAVES; ULTRASONOGRAPHY; X-RAY MICROTOMOGRAPHY;

EID: 84977615217     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0152898     Document Type: Article

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