Acute rat lung injury: Feasibility of assessment with micro-CT

Radiology

Volumn 233, Issue 1, 2004, Pages 165-171

  Langheinrich, Alexander Claus ^a   Leithäuser, Boris ^b   Greschus, Susanne ^a   Von Gerlach, Susanne ^a   Breithecker, Andreas ^a   Matthias, Fritz Reinhard ^a   Rau, Wigbert Stephan ^a   Bohle, Rainer Maria ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Animals; Computed tomography (CT), contrast enhancement; Computed tomography (CT), technology; Computed tomography (CT), tissue characterization; Experimental study Lung, CT

Indexed keywords

BARIUM SULFATE; CONTRAST MEDIUM; ENDOTOXIN; GELATIN; THYMOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DIAGNOSTIC VALUE; ELECTRON MICROSCOPY; EXTRAVASATION; HISTOPATHOLOGY; LUNG INJURY; NONHUMAN; PRIORITY JOURNAL; RAT; STATISTICAL ANALYSIS;

ANIMALS; BARIUM SULFATE; CAPILLARIES; CONTRAST MEDIA; ENDOTOXINS; FEASIBILITY STUDIES; GELATIN; IMAGE PROCESSING, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; LUNG; LUNG DISEASES; MALE; MICRORADIOGRAPHY; MICROSCOPY, ELECTRON; PULMONARY ALVEOLI; PULMONARY EDEMA; RATS; RATS, SPRAGUE-DAWLEY; THYMOL; TISSUE EMBEDDING; TOMOGRAPHY, X-RAY COMPUTED;

EID: 4644243975     PISSN: 00338419     EISSN: None     Source Type: Journal    
DOI: 10.1148/radiol.2331031340     Document Type: Article

References (44)

1. Rau WS, Hauenstein K, Mittermayer C, Volk P. A simple and rapid method for postmortem radiographic investigation of lung fine structure. Pathol Res Pract 1980; 170:426-432.
2. Rau WS, Mittermayer C. Volume controlled fixation of the lung by formalin vapor. ROFO Fortschr Geb Rontgenstr Nuklearmed 1980; 133:233-239. [German]
3. Mittermayer C, Wybitul K, Rau WS, Ostendorf P, Riede UN. Standardized fixation of human lung for radiology and morphometry: description of a "two chamber"-system with formaldehyde vapor inflation. Pathol Res Pract 1978; 162: 115-130.
4. Nettum JA. Combined vascular-bronchoalveolar casting using formalin-fixed canine lungs and a low viscosity silicone rubber. Anat Rec 1995; 243:479-482.
5. Bai C, Fukuda N, Song Y, Ma T, Matthay MA, Verkman AS. Lung fluid transport in aquaporin-1 and aquaporin-4 knockout mice. J Clin Invest 1999; 103:555-561.
6. Uhlig S, Brasch F, Wollin L, Fehrenbach H, Richter J, Wendel A. Functional and fine structural changes in isolated rat lungs challenged with endotoxin ex vivo and in vitro. Am J Pathol 1995; 146:1235-1247.
7. Mazzone RW, Durand CM, West JB. Electron microscopy of lung rapidly frozen under controlled physiological conditions. J Appl Physiol 1978; 45:325-333.
8. Feldkamp LA, Goldstein SA, Parfitt AM, Jension G, Kleerekoper M. The direct examination of three-dimensional bone architecture in vitro by computed tomography. J Bone Miner Res 1989; 4:3-11.
9. Jorgensen SM, Demirkaya O, Ritman EL. Three-dimensional imaging of vasculature and parenchyma in intact rodent organs with x-ray micro-CT. Am J Physiol 1998; 275(3 pt 2):H1103-H1114.
10. Lerman A, Ritman EL. Evaluation of microvascular anatomy by micro-CT. Herz 1999; 24:531-533.
11. Garcia-Sanz A, Rodriguez-Barbero A, Bentley MD, Riltman EL, Romero JC. Three-dimensional microcomputed tomography of renal vasculature in rats. Hypertension 1998; 31:440-444.
12. Ortiz MC, Garcia-Sanz A, Bentley MD, et al. Microcomputed tomography of kidneys following chronic bile duct ligation. Kidney Int 2000; 58:1632-1640.
13. Kwon HM, Sangiorgi G, Ritman EL, et al. Enhanced coronary vasa vasorum neovascularization in experimental hypercholesterolemia. J Clin Invest 1998; 101: 1551-1556.
14. Wan SY, Kiraly AP, Ritman EL, Higgins WE. Extraction of the hepatic vasculature in rats using 3-D micro-CT images. IEEE Trans Med Imaging 2000; 19:964-971.
15. Rodriguez-Porcel M, Lerman A, Ritman EL, Wilson S, Best PJ, Lerman LO. Altered myocardial microvasculature 3D architecture in experimental hypercholesterolemia. Circulation 2000; 102:2028-2030.
16. Pistoia W, van Rietbergen B, Laib A, Ruegsegger P. High-resolution three dimensional-pQCT images can be an adequate basis for in-vivo microFE analysis of bone. J Biomech Eng 2001; 123:176-183.
17. Langheinrich AC, Wienhard W, Vormann S, Hau B, Bohle RM, Zygmunt M. Analysis of the fetal placental villous tree by x-ray micro-computed tomography. Placenta 2004; 25:95-100.
18. Müller R, Van Campenhout H, Van Damme B. Morphometric analysis of human bone biopsies: a quantitative structural comparison of histological sections and micro-computed tomography. Bone 1998; 23:59-66.
19. Rojahn A. Origin and development of the animal welfare law. Dtsch Tierarztl Wochenschr 1993; 100:43-47.
20. Leithauser B, Schumacher J, Lendemanns S, Tillmanns H, Matthias FR. Antithrombin attenuates microvascular leakage and leukocyte-endothelial interaction in response to endotoxin. Semin Thromb Hemost 2002; 28(suppl 1):87-94.
21. Flannery BP, Deckman WG, Roberge WG, D'Amico KL. Three dimensional x-ray microtomography. Science 1987; 273:1439-1444.
22. Dover SD, Elliott JC, Boakes R, Bowen DK. Three dimensional x-ray microscopy with accurate registration of tomographic sections. J Microsc 1989; 153(pt 2):187-191.
23. Hoddad WS, McNulty I, Trebes JE, Anderson EH, Lernque RA, Yang L. Ultrahigh resolution x-ray tomography. Science 1994; 2:1213-1215.
24. Rathee S, Fallone BG, Robinson D. Modulation transfer function of digitally reconstructed radiographs using helical computed tomography. Med Phys 2002; 29:86-89.
25. Feldkamp LA. Practical cone-beam algorithm. J Opt Soc Am 1984; 1:612-619.
26. Spurr AR. A low-viscosity epoxy resin embedding medium for electron microscopy. J Ultrastruct Res 1969; 26:31-41.
27. Rabinovitch M, Gamble W, Nadas AS, Miettinen OS, Reid L. Rat pulmonary circulation after chronic hypoxia: hemodynamics and structural features. Am J Physiol 1979; 236:H818-H827.
28. Riley DJ, Thakker-Varia S, Poiani GJ, Tozzi CA. Vascular remodeling. In: The lung: scientific foundations. Philadelphia, Pa: Lippincott-Raven, 1997; 1589-1597.
29. Voelkel NF, Tudor RM. Hypoxia-induced pulmonary vascular remodelling: a model for what human disease? J Clin Invest 2000; 106:733-738.
30. Jacob HJ. Functional genomics and rat models. Genome Res 1999; 9:1013-1016.
31. Sato K, Webb S, Tucker A, et al. Factors influencing the idiopathic development of pulmonary hypertension in the fawn hooded rat. Am Rev Respir Dis 1992; 145: 793-797.
32. Karau KL, Johnson RH, Molthen RC, et al. Microfocal x-ray CT imaging and pulmonary arterial distensibility in excised rat lungs. Am J Physiol Heart Circ Physiol 2001; 281:H1447-H1457.
33. Karau KL, Molthen RC, Dhyani A, et al. Pulmonary arterial morphometry from microfocal x-ray computed tomography. Am J Physiol Heart Circ Physiol 2001; 281:H2747-H2756.
34. Beckmann N, Tigani B, Ekatodramis D, Borer R, Mazzoni L, Fozard JR. Pulmonary edema induced by allergen challenge in the rat: noninvasive assessment by magnetic resonance imaging. Magn Reson Med 2001; 45:88-95.
35. Scillia P, Kafi SA, Melot C, Keyzer C, Naeije R, Gevenois PA. Oleic acid-induced lung injury: thin-section CT evaluation in dogs. Radiology 2001; 219:724-731.
36. Shibata S, Ohdan H, Noriyuki T, Yoshioka S, Asahara T, Dohi K. Novel assessment of acute lung injury by in vivo near-infrared spectroscopy. Am J Respir Crit Care Med 1999; 160:317-323.
37. Hack CE, Zeerleder S. The endothelium in sepsis: source of and a target for inflammation. Crit Care Med 2001; 29(7 suppl): S21-S27.
38. McCuskey RS, Urbaschek R, Urbaschek B. The microcirculation during endotoxemia. Cardiovasc Res 1996; 32:752-763.
39. Lehr HA, Bittinger F, Kirkpatrick CJ. Microcirculatory dysfunction in sepsis: a pathogenetic basis for therapy? J Pathol 2000; 190:373-386.
40. Hulstrom D, Svensjo E. Intravital and electron microscopic study of bradykinin-induced vascular permeability changes using FITC-dextran as a tracer. J Pathol 1979; 129:125-133.
41. Kabir K, Gelinas JP, Chen M, et al. Characterization of a murine model of endotoxin-induced acute lung injury. Shock 2002; 17:300-303.
42. Fehrenbach A, Fehrenbach H, Wittwer T, Ochs M, Wahlers T, Richter J. Evaluation of pulmonary edema: stereological versus gravimetrical analysis. Eur Surg Res 2001; 33:270-278.
43. Holguin F, Moss I, Brown LA, Guidot DM. Chronic ethanol ingestion impairs alveolar type II cell glutathione homeostasis and function and predisposes to endotox-in-mediated acute edematous lung injury in rats. J Clin Invest 1998; 101:761-768.
44. Raven C. Numerical removal ring artefacts in microtomography. Rev Sci Instrum 1998; 69:2978-2980.