The tumor-associated glycosyltransferase ST6Gal-I regulates stem cell transcription factors and confers a cancer stem cell phenotype

Cancer Research

Volumn 76, Issue 13, 2016, Pages 3978-3988

  Schultz, Matthew J ^a   Holdbrooks, Andrew T ^a   Chakraborty, Asmi ^a   Grizzle, William E ^b   Landen, Charles N ^c   Buchsbaum, Donald J ^d   Conner, Michael G ^e   Arend, Rebecca C ^e   Yoon, Karina J ^f   Klug, Christopher A ^g   Bullard, Daniel C ^h   Kesterson, Robert A ^h   Oliver, Patsy G ^d   O'Connor, Amber K ^a   Yoder, Bradley K ^a   Bellis, Susan L ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b University of Alabama at Birmingham   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

^d The University of Alabama at Birmingham   (United States)

^e UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^f University of Alabama at Birmingham   (United States)

^g University of Alabama at Birmingham   (United States)

^h UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDE ALPHA2 6 SIALYLTRANSFERASE 1; GEMCITABINE; GLYCOSYLTRANSFERASE; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; LEUKOCYTE ANTIGEN; SIALYLTRANSFERASE; SNAI1 PROTEIN, HUMAN; SOX9 PROTEIN, HUMAN; ST6GAL1 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SNAIL; TUMOR MARKER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASCITES; CANCER CELL; CANCER STEM CELL; CANCER SURVIVAL; CARCINOGENESIS; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DRUG RESISTANCE; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCOMPETENT CELL; METASTASIS; MOUSE; NONHUMAN; OVARY CARCINOMA; PANCREAS CANCER; PANCREAS CARCINOMA; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIALYLATION; SOLID TUMOR; STEM CELL CULTURE; TRANSGENIC MOUSE; TUMOR SPHEROID; TUMOR XENOGRAFT; UPREGULATION; ANIMAL; APOPTOSIS; C57BL MOUSE; CANCER STAGING; CASE CONTROL STUDY; CELL PROLIFERATION; COHORT ANALYSIS; COMPARATIVE STUDY; DRUG SCREENING; GENETICS; GLYCOSYLATION; LYMPH NODE METASTASIS; METABOLISM; NONOBESE DIABETIC MOUSE; OVARIAN NEOPLASMS; PANCREATIC NEOPLASMS; PATHOLOGY; PROGNOSIS; SCID MOUSE; SURVIVAL RATE; TUMOR CELL CULTURE;

ANIMALS; ANTIGENS, CD; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; BIOMARKERS, TUMOR; CASE-CONTROL STUDIES; CELL PROLIFERATION; COHORT STUDIES; FEMALE; GLYCOSYLATION; HUMANS; LYMPHATIC METASTASIS; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; MICE, SCID; MICE, TRANSGENIC; NEOPLASM STAGING; NEOPLASTIC STEM CELLS; OVARIAN NEOPLASMS; PANCREATIC NEOPLASMS; PHENOTYPE; PROGNOSIS; SIALYLTRANSFERASES; SNAIL FAMILY TRANSCRIPTION FACTORS; SOX9 TRANSCRIPTION FACTOR; SURVIVAL RATE; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84977578357     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-15-2834     Document Type: Article

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