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Volumn 76, Issue 13, 2016, Pages 3666-3670

OncomiR or tumor suppressor? The duplicity of MicroRNAs in cancer

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; MICRORNA; MICRORNA 122; MICRORNA 125B; MICRORNA 155; MICRORNA 214; MIRAVIRSEN; ONCOGENIC MICRORNA; PROTEIN BCL 2; UNCLASSIFIED DRUG;

EID: 84977553065     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-16-0359     Document Type: Review
Times cited : (615)

References (33)
  • 1
    • 77956339881 scopus 로고    scopus 로고
    • Oncomi R addiction in an in vivo model of micro RNA-21-induced pre-B-cell lymphoma
    • Medina PP, Nolde M, Slack FJ. Oncomi R addiction in an in vivo model of micro RNA-21-induced pre-B-cell lymphoma. Nature 2010;467:86-90.
    • (2010) Nature , vol.467 , pp. 86-90
    • Medina, P.P.1    Nolde, M.2    Slack, F.J.3
  • 3
    • 84872155023 scopus 로고    scopus 로고
    • Diverse functions of MIR-125 family in different cell contexts
    • Sun YM, Lin KY, Chen YQ. Diverse functions of miR-125 family in different cell contexts. J Hematol Oncol 2013;6:6.
    • (2013) J Hematol Oncol , vol.6 , pp. 6
    • Sun, Y.M.1    Lin, K.Y.2    Chen, Y.Q.3
  • 4
    • 84866870458 scopus 로고    scopus 로고
    • The downregulation of MIR-125b in chronic lymphocytic leukemias leads tometabolic adaptation of cells to a transformed state
    • Tili E, Michaille JJ, Luo Z, Volinia S, Rassenti LZ, Kipps TJ, et al. The downregulation of miR-125b in chronic lymphocytic leukemias leads tometabolic adaptation of cells to a transformed state. Blood 2012;120:2631-8.
    • (2012) Blood , vol.120 , pp. 2631-2638
    • Tili, E.1    Michaille, J.J.2    Luo, Z.3    Volinia, S.4    Rassenti, L.Z.5    Kipps, T.J.6
  • 5
    • 84863116430 scopus 로고    scopus 로고
    • Substantial susceptibility of chronic lymphocytic leukemia to BCL2 inhibition: Results of a phase I study of navitoclax in patients with relapsed or refractory disease
    • Roberts AW, Seymour JF, Brown JR, Wierda WG, Kipps TJ, Khaw SL, et al. Substantial susceptibility of chronic lymphocytic leukemia to BCL2 inhibition: results of a phase I study of navitoclax in patients with relapsed or refractory disease. J Clin Oncol 2012;30:488-96.
    • (2012) J Clin Oncol , vol.30 , pp. 488-496
    • Roberts, A.W.1    Seymour, J.F.2    Brown, J.R.3    Wierda, W.G.4    Kipps, T.J.5    Khaw, S.L.6
  • 7
    • 84924424616 scopus 로고    scopus 로고
    • Micro RNA silencing for cancer therapy targeted to the tumour microenvironment
    • Cheng CJ, Bahal R, Babar IA, Pincus Z, Barrera F, Liu C, et al. Micro RNA silencing for cancer therapy targeted to the tumour microenvironment. Nature 2015;518:107-10.
    • (2015) Nature , vol.518 , pp. 107-110
    • Cheng, C.J.1    Bahal, R.2    Babar, I.A.3    Pincus, Z.4    Barrera, F.5    Liu, C.6
  • 8
    • 84893745114 scopus 로고    scopus 로고
    • Upregulation of miRNA-155 promotes tumour angiogenesis by targeting VHL and is associated with poor prognosis and triple-negative breast cancer
    • Kong W, He L, Richards EJ, Challa S, Xu CX, Permuth-Wey J, et al. Upregulation of miRNA-155 promotes tumour angiogenesis by targeting VHL and is associated with poor prognosis and triple-negative breast cancer. Oncogene 2014;33:679-89.
    • (2014) Oncogene , vol.33 , pp. 679-689
    • Kong, W.1    He, L.2    Richards, E.J.3    Challa, S.4    Xu, C.X.5    Permuth-Wey, J.6
  • 10
    • 84860732927 scopus 로고    scopus 로고
    • Micro RNA-155 is downregulated in gastric cancer cells and involved in cell metastasis
    • Li CL, Nie H, Wang M, Su LP, Li JF, Yu YY, et al. micro RNA-155 is downregulated in gastric cancer cells and involved in cell metastasis. Oncol Rep 2012;27:1960-6.
    • (2012) Oncol Rep , vol.27 , pp. 1960-1966
    • Li, C.L.1    Nie, H.2    Wang, M.3    Su, L.P.4    Li, J.F.5    Yu, Y.Y.6
  • 11
    • 84876465381 scopus 로고    scopus 로고
    • Micro RNA-155 is a novel suppressor of ovarian cancer-initiating cells that targets CLDN1
    • Qin W, Ren Q, Liu T, Huang Y, Wang J. Micro RNA-155 is a novel suppressor of ovarian cancer-initiating cells that targets CLDN1. FEBS Lett 2013;587: 1434-9.
    • (2013) FEBS Lett , vol.587 , pp. 1434-1439
    • Qin, W.1    Ren, Q.2    Liu, T.3    Huang, Y.4    Wang, J.5
  • 12
    • 84899896641 scopus 로고    scopus 로고
    • Micro RNA-155 as an inducer of apoptosis and cell differentiation in acute myeloid leukaemia
    • Palma CA, Al Sheikha D, Lim TK, Bryant A, Vu TT, Jayaswal V, et al. Micro RNA-155 as an inducer of apoptosis and cell differentiation in Acute Myeloid Leukaemia. Mol Cancer 2014;13:79.
    • (2014) Mol Cancer , vol.13 , pp. 79
    • Palma, C.A.1    Al Sheikha, D.2    Lim, T.K.3    Bryant, A.4    Vu, T.T.5    Jayaswal, V.6
  • 13
    • 54249117763 scopus 로고    scopus 로고
    • A SNP in a let- 7 micro RNA complementary site in the KRAS 3′ untranslated region increases non-small cell lung cancer risk
    • Chin LJ, Ratner E, Leng S, Zhai R, Nallur S, Babar I, et al. A SNP in a let- 7 micro RNA complementary site in the KRAS 3′ untranslated region increases non-small cell lung cancer risk. Cancer Res 2008;68:8535-40.
    • (2008) Cancer Res , vol.68 , pp. 8535-8540
    • Chin, L.J.1    Ratner, E.2    Leng, S.3    Zhai, R.4    Nallur, S.5    Babar, I.6
  • 14
    • 70349741005 scopus 로고    scopus 로고
    • A risk variant in an MIR-125b binding site in BMPR1B is associated with breast cancer pathogenesis
    • Saetrom P, Biesinger J, Li SM, Smith D, Thomas LF, Majzoub K, et al. A risk variant in an miR-125b binding site in BMPR1B is associated with breast cancer pathogenesis. Cancer Res 2009;69:7459-65.
    • (2009) Cancer Res , vol.69 , pp. 7459-7465
    • Saetrom, P.1    Biesinger, J.2    Li, S.M.3    Smith, D.4    Thomas, L.F.5    Majzoub, K.6
  • 15
    • 78650046221 scopus 로고    scopus 로고
    • Complete characterization of the micro RNA ome in a patient with acute myeloid leukemia
    • Ramsingh G, Koboldt DC, Trissal M, Chiappinelli KB, Wylie T, Koul S, et al. Complete characterization of the micro RNA ome in a patient with acute myeloid leukemia. Blood 2010;116:5316-26.
    • (2010) Blood , vol.116 , pp. 5316-5326
    • Ramsingh, G.1    Koboldt, D.C.2    Trissal, M.3    Chiappinelli, K.B.4    Wylie, T.5    Koul, S.6
  • 16
    • 84882805962 scopus 로고    scopus 로고
    • MIR-155-deficient bone marrow promotes tumor metastasis
    • Yu F, Jia X, Du F, Wang J, Wang Y, Ai W, et al. miR-155-deficient bone marrow promotes tumor metastasis. Mol Cancer Res 2013;11:923-36.
    • (2013) Mol Cancer Res , vol.11 , pp. 923-936
    • Yu, F.1    Jia, X.2    Du, F.3    Wang, J.4    Wang, Y.5    Ai, W.6
  • 17
    • 84884478648 scopus 로고    scopus 로고
    • A role for MIR-155 in enabling tumor-infiltrating innate immune cells to mount effective antitumor responses in mice
    • Zonari E, Pucci F, Saini M, Mazzieri R, Politi LS, Gentner B, et al. A role for miR-155 in enabling tumor-infiltrating innate immune cells to mount effective antitumor responses in mice. Blood 2013;122:243-52.
    • (2013) Blood , vol.122 , pp. 243-252
    • Zonari, E.1    Pucci, F.2    Saini, M.3    Mazzieri, R.4    Politi, L.S.5    Gentner, B.6
  • 18
    • 84859386994 scopus 로고    scopus 로고
    • Reprogramming tumor-associated dendritic cells in vivo using miRNA mimetics triggers protective immunity against ovarian cancer
    • Cubillos-Ruiz JR, Baird JR, Tesone AJ, Rutkowski MR, Scarlett UK, Camposeco-Jacobs AL, et al. Reprogramming tumor-associated dendritic cells in vivo using miRNA mimetics triggers protective immunity against ovarian cancer. Cancer Res 2012;72:1683-93.
    • (2012) Cancer Res , vol.72 , pp. 1683-1693
    • Cubillos-Ruiz, J.R.1    Baird, J.R.2    Tesone, A.J.3    Rutkowski, M.R.4    Scarlett, U.K.5    Camposeco-Jacobs, A.L.6
  • 19
    • 84900441668 scopus 로고    scopus 로고
    • MIR-30 as a tumor suppressor connects EGF/Src signal to ERG and EMT
    • Kao CJ, Martiniez A, Shi XB, Yang J, Evans CP, Dobi A, et al. miR-30 as a tumor suppressor connects EGF/Src signal to ERG and EMT. Oncogene 2014;33:2495-503.
    • (2014) Oncogene , vol.33 , pp. 2495-2503
    • Kao, C.J.1    Martiniez, A.2    Shi, X.B.3    Yang, J.4    Evans, C.P.5    Dobi, A.6
  • 20
    • 84875113959 scopus 로고    scopus 로고
    • MIR-30d induces apoptosis and is regulated by the Akt/FOXO pathway in renal cell carcinoma
    • Wu C, Jin B, Chen L, Zhuo D, Zhang Z, Gong K, et al. MiR-30d induces apoptosis and is regulated by the Akt/FOXO pathway in renal cell carcinoma. Cell Signal 2013;25:1212-21.
    • (2013) Cell Signal , vol.25 , pp. 1212-1221
    • Wu, C.1    Jin, B.2    Chen, L.3    Zhuo, D.4    Zhang, Z.5    Gong, K.6
  • 22
    • 84871528926 scopus 로고    scopus 로고
    • Micro RNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer
    • Mitra AK, Zillhardt M, Hua Y, Tiwari P, Murmann AE, Peter ME, et al. Micro RNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer. Cancer Discov 2012;2:1100-8.
    • (2012) Cancer Discov , vol.2 , pp. 1100-1108
    • Mitra, A.K.1    Zillhardt, M.2    Hua, Y.3    Tiwari, P.4    Murmann, A.E.5    Peter, M.E.6
  • 23
    • 84867417506 scopus 로고    scopus 로고
    • Micro RNA MIR- 214 regulates ovarian cancer cell stemness by targeting p53/Nanog
    • Xu CX, Xu M, Tan L, Yang H, Permuth-Wey J, Kruk PA, et al. Micro RNA miR- 214 regulates ovarian cancer cell stemness by targeting p53/Nanog. J Biol Chem 2012;287:34970-8.
    • (2012) J Biol Chem , vol.287 , pp. 34970-34978
    • Xu, C.X.1    Xu, M.2    Tan, L.3    Yang, H.4    Permuth-Wey, J.5    Kruk, P.A.6
  • 24
    • 84926151514 scopus 로고    scopus 로고
    • Tumor-secreted MIR-214 induces regulatory T cells: A major link between immune evasion and tumor growth
    • Yin Y, Cai X, Chen X, Liang H, Zhang Y, Li J, et al. Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth. Cell Res 2014;24:1164-80.
    • (2014) Cell Res , vol.24 , pp. 1164-1180
    • Yin, Y.1    Cai, X.2    Chen, X.3    Liang, H.4    Zhang, Y.5    Li, J.6
  • 25
    • 79961168650 scopus 로고    scopus 로고
    • MIR-155 promotes macroscopic tumor formation yet inhibits tumor dissemination from mammary fat pads to the lung by preventing EMT
    • Xiang X, Zhuang X, Ju S, Zhang S, Jiang H, Mu J, et al. miR-155 promotes macroscopic tumor formation yet inhibits tumor dissemination from mammary fat pads to the lung by preventing EMT. Oncogene 2011;30: 3440-53.
    • (2011) Oncogene , vol.30 , pp. 3440-3453
    • Xiang, X.1    Zhuang, X.2    Ju, S.3    Zhang, S.4    Jiang, H.5    Mu, J.6
  • 26
    • 66149114383 scopus 로고    scopus 로고
    • Micro RNA-122, a tumor suppressor micro RNA that regulates intrahepatic metastasis of hepatocellular carcinoma
    • Tsai WC, Hsu PW, Lai TC, Chau GY, Lin CW, Chen CM, et al. Micro RNA-122, a tumor suppressor micro RNA that regulates intrahepatic metastasis of hepatocellular carcinoma. Hepatology 2009;49: 1571-82.
    • (2009) Hepatology , vol.49 , pp. 1571-1582
    • Tsai, W.C.1    Hsu, P.W.2    Lai, T.C.3    Chau, G.Y.4    Lin, C.W.5    Chen, C.M.6
  • 29
    • 84896912382 scopus 로고    scopus 로고
    • Protective role of MIR-155 in breast cancer through RAD51 targeting impairs homologous recombination after irradiation
    • Gasparini P, Lovat F, Fassan M, Casadei L, Cascione L, Jacob NK, et al. Protective role of miR-155 in breast cancer through RAD51 targeting impairs homologous recombination after irradiation. Proc Natl Acad Sci U S A 2014;111:4536-41.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 4536-4541
    • Gasparini, P.1    Lovat, F.2    Fassan, M.3    Casadei, L.4    Cascione, L.5    Jacob, N.K.6
  • 32
    • 78449268612 scopus 로고    scopus 로고
    • EGFR promotes lung tumorigenesis by activatingmiR-7 through a Ras/ERK/Myc pathway that targets the Ets2 transcriptional repressor ERF
    • Chou YT, Lin HH, Lien YC, Wang YH, Hong CF, Kao YR, et al. EGFR promotes lung tumorigenesis by activatingmiR-7 through a Ras/ERK/Myc pathway that targets the Ets2 transcriptional repressor ERF. Cancer Res 2010;70:8822-31.
    • (2010) Cancer Res , vol.70 , pp. 8822-8831
    • Chou, Y.T.1    Lin, H.H.2    Lien, Y.C.3    Wang, Y.H.4    Hong, C.F.5    Kao, Y.R.6
  • 33
    • 77956995581 scopus 로고    scopus 로고
    • Alterations of micro RNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin
    • Pogribny IP, Filkowski JN, Tryndyak VP, Golubov A, Shpyleva SI, Kovalchuk O. Alterations of micro RNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin. Int J Cancer 2010;127:1785-94.
    • (2010) Int J Cancer , vol.127 , pp. 1785-1794
    • Pogribny, I.P.1    Filkowski, J.N.2    Tryndyak, V.P.3    Golubov, A.4    Shpyleva, S.I.5    Kovalchuk, O.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.