-
1
-
-
84904439264
-
Challenges for children and adolescents with cancer in Europe: the SIOP-Europe agenda
-
Vassal G, Fitzgerald E, Schrappe M, Arnold F, Kowalczyk J, Walker D, et al. Challenges for children and adolescents with cancer in Europe: the SIOP-Europe agenda. Pediatr Blood Cancer 2014;61:1551-1557.
-
(2014)
Pediatr Blood Cancer
, vol.61
, pp. 1551-1557
-
-
Vassal, G.1
Fitzgerald, E.2
Schrappe, M.3
Arnold, F.4
Kowalczyk, J.5
Walker, D.6
-
2
-
-
0037096813
-
Hepatocellular carcinoma in children and adolescents: results from the Pediatric Oncology Group and the Children's Cancer Group intergroup study
-
Katzenstein HM, Krailo MD, Malogolowkin MH, Ortega JA, Liu-Mares W, Douglass EC, et al. Hepatocellular carcinoma in children and adolescents: results from the Pediatric Oncology Group and the Children's Cancer Group intergroup study. J Clin Oncol 2002;20:2789-2797.
-
(2002)
J Clin Oncol
, vol.20
, pp. 2789-2797
-
-
Katzenstein, H.M.1
Krailo, M.D.2
Malogolowkin, M.H.3
Ortega, J.A.4
Liu-Mares, W.5
Douglass, E.C.6
-
3
-
-
0037096891
-
Liver Tumors Study Group of the International Society of Pediatric Oncology. Hepatocellular carcinoma in children: results of the first prospective study of the International Society of Pediatric Oncology group
-
Czauderna P, Mackinlay G, Perilongo G, Brown J, Shafford E, Aronson D, et al. Liver Tumors Study Group of the International Society of Pediatric Oncology. Hepatocellular carcinoma in children: results of the first prospective study of the International Society of Pediatric Oncology group. J Clin Oncol 2002;20:2798-2804.
-
(2002)
J Clin Oncol
, vol.20
, pp. 2798-2804
-
-
Czauderna, P.1
Mackinlay, G.2
Perilongo, G.3
Brown, J.4
Shafford, E.5
Aronson, D.6
-
4
-
-
0036836485
-
Adult type vs. childhood hepatocellular carcinoma—are they the same or different lesions? Biology, natural history, prognosis, and treatment
-
Czauderna P. Adult type vs. childhood hepatocellular carcinoma—are they the same or different lesions? Biology, natural history, prognosis, and treatment. Med Pediatr Oncol 2002;39:519-523.
-
(2002)
Med Pediatr Oncol
, vol.39
, pp. 519-523
-
-
Czauderna, P.1
-
5
-
-
0036836487
-
Transitional liver cell tumors (TLCT) in older children and adolescents: a novel group of aggressive hepatic tumors expressing beta-catenin
-
Prokurat A, Kluge P, Kościesza A, Perek D, Kappeler A, Zimmermann A. Transitional liver cell tumors (TLCT) in older children and adolescents: a novel group of aggressive hepatic tumors expressing beta-catenin. Med Pediatr Oncol 2002;39:510-518.
-
(2002)
Med Pediatr Oncol
, vol.39
, pp. 510-518
-
-
Prokurat, A.1
Kluge, P.2
Kościesza, A.3
Perek, D.4
Kappeler, A.5
Zimmermann, A.6
-
6
-
-
22144477149
-
The emerging family of hepatoblastoma tumors: from ontogenesis to oncogenesis
-
Zimmermann A. The emerging family of hepatoblastoma tumors: from ontogenesis to oncogenesis. Eur J Cancer 2005;41:1503-1514.
-
(2005)
Eur J Cancer
, vol.41
, pp. 1503-1514
-
-
Zimmermann, A.1
-
8
-
-
20444466479
-
Elevated expression of wnt antagonists is a common event in hepatoblastomas
-
Koch A, Waha A, Hartmann W, Hrychyk A, Schuller U, Wharton KA, et al. Elevated expression of wnt antagonists is a common event in hepatoblastomas. Clin Cancer Res 2005;11:4295-4304.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4295-4304
-
-
Koch, A.1
Waha, A.2
Hartmann, W.3
Hrychyk, A.4
Schuller, U.5
Wharton, K.A.6
-
9
-
-
0037130449
-
Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas
-
Taniguchi K, Roberts LR, Aderca IN, Dong X, Qian C, Murphy LM, et al. Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas. Oncogene 2002;21:4863-4871.
-
(2002)
Oncogene
, vol.21
, pp. 4863-4871
-
-
Taniguchi, K.1
Roberts, L.R.2
Aderca, I.N.3
Dong, X.4
Qian, C.5
Murphy, L.M.6
-
10
-
-
0034719407
-
Activation of beta-catenin in epithelial and mesenchymal hepatoblastomas
-
Wei Y, Fabre M, Branchereau S, Gauthier F, Perilongo G, Buendia MA. Activation of beta-catenin in epithelial and mesenchymal hepatoblastomas. Oncogene 2000;19:498-504.
-
(2000)
Oncogene
, vol.19
, pp. 498-504
-
-
Wei, Y.1
Fabre, M.2
Branchereau, S.3
Gauthier, F.4
Perilongo, G.5
Buendia, M.A.6
-
11
-
-
23944461569
-
The spectrum of APC mutations in children with hepatoblastoma from familial adenomatous polyposis kindreds
-
Hirschman BA, Pollock BH, Tomlinson GE. The spectrum of APC mutations in children with hepatoblastoma from familial adenomatous polyposis kindreds. J Pediatr 2005;147:263-266.
-
(2005)
J Pediatr
, vol.147
, pp. 263-266
-
-
Hirschman, B.A.1
Pollock, B.H.2
Tomlinson, G.E.3
-
12
-
-
0038517691
-
Hepatoblastoma associated with Beckwith-Wiedemann syndrome and hemihypertrophy
-
Hamada Y, Takada K, Fukunaga S, Hioki K. Hepatoblastoma associated with Beckwith-Wiedemann syndrome and hemihypertrophy. Pediatr Surg Int 2003;19:112-114.
-
(2003)
Pediatr Surg Int
, vol.19
, pp. 112-114
-
-
Hamada, Y.1
Takada, K.2
Fukunaga, S.3
Hioki, K.4
-
13
-
-
70350333890
-
Cisplatin versus cisplatin plus doxorubicin for standard-risk hepatoblastoma
-
Perilongo G, Maibach R, Shafford E, Brugieres L, Brock P, Morland B, et al. Cisplatin versus cisplatin plus doxorubicin for standard-risk hepatoblastoma. N Engl J Med 2009;361:1662-1670.
-
(2009)
N Engl J Med
, vol.361
, pp. 1662-1670
-
-
Perilongo, G.1
Maibach, R.2
Shafford, E.3
Brugieres, L.4
Brock, P.5
Morland, B.6
-
14
-
-
84862011232
-
Prognostic stratification for children with hepatoblastoma: the SIOPEL experience
-
Maibach R, Roebuck D, Brugieres L, Capra M, Brock P, Dall'Igna P, et al. Prognostic stratification for children with hepatoblastoma: the SIOPEL experience. Eur J Cancer 2012;48:1543-1549.
-
(2012)
Eur J Cancer
, vol.48
, pp. 1543-1549
-
-
Maibach, R.1
Roebuck, D.2
Brugieres, L.3
Capra, M.4
Brock, P.5
Dall'Igna, P.6
-
15
-
-
77956405067
-
Successful treatment of childhood high-risk hepatoblastoma with dose-intensive multiagent chemotherapy and surgery: final results of the SIOPEL-3HR study
-
Zsíros J, Maibach R, Shafford E, Brugieres L, Brock P, Czauderna P, et al. Successful treatment of childhood high-risk hepatoblastoma with dose-intensive multiagent chemotherapy and surgery: final results of the SIOPEL-3HR study. J Clin Oncol 2010;28:2584-2590.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2584-2590
-
-
Zsíros, J.1
Maibach, R.2
Shafford, E.3
Brugieres, L.4
Brock, P.5
Czauderna, P.6
-
16
-
-
84880844862
-
International Childhood Liver Tumours Strategy Group (SIOPEL). Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4): a prospective, single-arm, feasibility study
-
Zsiros J, Brugieres L, Brock P, Roebuck D, Maibach R, Zimmermann A, et al. International Childhood Liver Tumours Strategy Group (SIOPEL). Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4): a prospective, single-arm, feasibility study. Lancet Oncol 2013;14:834-842.
-
(2013)
Lancet Oncol
, vol.14
, pp. 834-842
-
-
Zsiros, J.1
Brugieres, L.2
Brock, P.3
Roebuck, D.4
Maibach, R.5
Zimmermann, A.6
-
17
-
-
84922267671
-
Exome sequencing of hepatoblastoma reveals novel mutations and cancer genes in the Wnt pathway and ubiquitin ligase complex
-
Jia D, Dong R, Jing Y, Xu D, Wang Q, Chen L, et al. Exome sequencing of hepatoblastoma reveals novel mutations and cancer genes in the Wnt pathway and ubiquitin ligase complex. Hepatology 2014;60:1686-1696.
-
(2014)
Hepatology
, vol.60
, pp. 1686-1696
-
-
Jia, D.1
Dong, R.2
Jing, Y.3
Xu, D.4
Wang, Q.5
Chen, L.6
-
18
-
-
84922233037
-
The genomic landscape of hepatoblastoma and their progenies with HCC-like features
-
Eichenmüller M, Trippel F, Kreuder M, Beck A, Schwarzmayr T, Häberle B, et al. The genomic landscape of hepatoblastoma and their progenies with HCC-like features. J Hepatol 2014;61:1312-1320.
-
(2014)
J Hepatol
, vol.61
, pp. 1312-1320
-
-
Eichenmüller, M.1
Trippel, F.2
Kreuder, M.3
Beck, A.4
Schwarzmayr, T.5
Häberle, B.6
-
19
-
-
84938530111
-
Individual exome analysis in diagnosis and management of pediatric liver failure of indeterminate aetiology
-
Vilarinho S, Choi M, Jain D, Malhotra A, Kulkarni S, Pashankar D, et al. Individual exome analysis in diagnosis and management of pediatric liver failure of indeterminate aetiology. J Hepatol 2014;61:1056-1063.
-
(2014)
J Hepatol
, vol.61
, pp. 1056-1063
-
-
Vilarinho, S.1
Choi, M.2
Jain, D.3
Malhotra, A.4
Kulkarni, S.5
Pashankar, D.6
-
20
-
-
84896732099
-
Detection of a recurrent DNAJB1-PRKACA chimeric transcript in fibrolamellar hepatocellular carcinoma
-
Honeyman JN, Simon EP, Robine N, Chiaroni-Clarke R, Darcy DG, Lim II, et al. Detection of a recurrent DNAJB1-PRKACA chimeric transcript in fibrolamellar hepatocellular carcinoma. Science 2014;343:1010-1014.
-
(2014)
Science
, vol.343
, pp. 1010-1014
-
-
Honeyman, J.N.1
Simon, E.P.2
Robine, N.3
Chiaroni-Clarke, R.4
Darcy, D.G.5
Lim, I.I.6
-
21
-
-
84864746573
-
A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers
-
Lee RS, Stewart C, Carter SL, Ambrogio L, Cibulskis K, Sougnez C, et al. A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers. J Clin Invest 2012;122:2983-2988.
-
(2012)
J Clin Invest
, vol.122
, pp. 2983-2988
-
-
Lee, R.S.1
Stewart, C.2
Carter, S.L.3
Ambrogio, L.4
Cibulskis, K.5
Sougnez, C.6
-
22
-
-
84905993912
-
β-catenin activation in a novel liver progenitor cell type is sufficient to cause hepatocellular carcinoma and hepatoblastoma
-
Mokkapati S, Niopek K, Huang L, Cunniff KJ, Ruteshouser EC, deCaestecker M, et al. β-catenin activation in a novel liver progenitor cell type is sufficient to cause hepatocellular carcinoma and hepatoblastoma. Cancer Res 2014;74:4515-4525.
-
(2014)
Cancer Res
, vol.74
, pp. 4515-4525
-
-
Mokkapati, S.1
Niopek, K.2
Huang, L.3
Cunniff, K.J.4
Ruteshouser, E.C.5
deCaestecker, M.6
-
23
-
-
84939654756
-
Nrf2, but not β-catenin, mutation represents an early event in rat hepatocarcinogenesis
-
Zavattari P, Perra A, Menegon S, Kowalik MA, Petrelli A, Angioni MM, et al. Nrf2, but not β-catenin, mutation represents an early event in rat hepatocarcinogenesis. Hepatology 2015;62:851-862.
-
(2015)
Hepatology
, vol.62
, pp. 851-862
-
-
Zavattari, P.1
Perra, A.2
Menegon, S.3
Kowalik, M.A.4
Petrelli, A.5
Angioni, M.M.6
-
25
-
-
84946209341
-
High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response
-
Gao H, Korn JM, Ferretti S, Monahan JE, Wang Y, Singh M, et al. High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response. Nat Med 2015;21:1318-1325.
-
(2015)
Nat Med
, vol.21
, pp. 1318-1325
-
-
Gao, H.1
Korn, J.M.2
Ferretti, S.3
Monahan, J.E.4
Wang, Y.5
Singh, M.6
-
26
-
-
0019975565
-
Establishment of an experimental model of human hepatoblastoma
-
Hata Y, Uchino J, Sato K, Sasaki F, Une Y, Naito H, et al. Establishment of an experimental model of human hepatoblastoma. Cancer 1982;50:97-101.
-
(1982)
Cancer
, vol.50
, pp. 97-101
-
-
Hata, Y.1
Uchino, J.2
Sato, K.3
Sasaki, F.4
Une, Y.5
Naito, H.6
-
27
-
-
0028971932
-
Proliferation and differentiation of a human hepatoblastoma transplanted in the Nude mouse
-
Desdouets C, Fabre M, Gauthier F, Bréchot C, Sobczak-Thépot J. Proliferation and differentiation of a human hepatoblastoma transplanted in the Nude mouse. J Hepatol 1995;23:569-577.
-
(1995)
J Hepatol
, vol.23
, pp. 569-577
-
-
Desdouets, C.1
Fabre, M.2
Gauthier, F.3
Bréchot, C.4
Sobczak-Thépot, J.5
-
28
-
-
0029788250
-
Successful transplantation of human hepatoblastoma into immunodeficient mice
-
Fuchs J, Schmidt D, Pietsch T, Miller K, von Schweinitz D. Successful transplantation of human hepatoblastoma into immunodeficient mice. J Pediatr Surg 1996;31:1241-1246.
-
(1996)
J Pediatr Surg
, vol.31
, pp. 1241-1246
-
-
Fuchs, J.1
Schmidt, D.2
Pietsch, T.3
Miller, K.4
von Schweinitz, D.5
-
29
-
-
57049182539
-
Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer
-
Cairo S, Armengol C, De Reyniès A, Wei Y, Thomas E, Renard CA, et al. Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer. Cancer Cell 2008; 14:471-484.
-
(2008)
Cancer Cell
, vol.14
, pp. 471-484
-
-
Cairo, S.1
Armengol, C.2
De Reyniès, A.3
Wei, Y.4
Thomas, E.5
Renard, C.A.6
-
30
-
-
84965039431
-
-
Vienna, Austria, R Foundation for Statistical Computing
-
R Development Core Team. R: A Language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical Computing; 2012. ISBN 3-900051-07-0.
-
(2012)
R: A Language and Environment for Statistical Computing
-
-
-
32
-
-
84863904225
-
Antitumor activity of targeted and cytotoxic agents in murine subcutaneous tumor models correlates with clinical response
-
Wong H, Choo EF, Alicke B, Ding X, La H, McNamara E, et al. Antitumor activity of targeted and cytotoxic agents in murine subcutaneous tumor models correlates with clinical response. Clin Cancer Res 2012;18:3846-3855.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 3846-3855
-
-
Wong, H.1
Choo, E.F.2
Alicke, B.3
Ding, X.4
La, H.5
McNamara, E.6
-
33
-
-
84988281968
-
-
Accessed on June 1, 2016
-
National Cancer Institute PPTP program. Testing and analysis methods, http://ctep.cancer.gov/content/docs/PPPTP_TESTING_AND_ANALYSIS_METHODS.pdf. Accessed on: June 1, 2016.
-
Testing and analysis methods
-
-
-
34
-
-
84937634186
-
Clinical utility of patient-derived xenografts to determine biomarkers of prognosis and map resistance pathways in EGFR-mutant lung adenocarcinoma
-
Stewart EL, Mascaux C, Pham NA, Sakashita S, Sykes J, Kim L, et al. Clinical utility of patient-derived xenografts to determine biomarkers of prognosis and map resistance pathways in EGFR-mutant lung adenocarcinoma. J Clin Oncol 2015;33:2472-2480.
-
(2015)
J Clin Oncol
, vol.33
, pp. 2472-2480
-
-
Stewart, E.L.1
Mascaux, C.2
Pham, N.A.3
Sakashita, S.4
Sykes, J.5
Kim, L.6
-
36
-
-
0033900096
-
Characterization of genomic alterations in hepatoblastomas. A role for gains on chromosomes 8q and 20 as predictors of poor outcome
-
Weber RG, Pietsch T, von Schweinitz D, Lichter P. Characterization of genomic alterations in hepatoblastomas. A role for gains on chromosomes 8q and 20 as predictors of poor outcome. Am J Pathol 2000;157:571-578.
-
(2000)
Am J Pathol
, vol.157
, pp. 571-578
-
-
Weber, R.G.1
Pietsch, T.2
von Schweinitz, D.3
Lichter, P.4
-
38
-
-
77950424592
-
Hepatocyte growth factor protects hepatoblastoma cells from chemotherapy-induced apoptosis by AKT activation
-
Grotegut S, Kappler R, Tarimoradi S, Lehembre F, Christofori G, Von Schweinitz D. Hepatocyte growth factor protects hepatoblastoma cells from chemotherapy-induced apoptosis by AKT activation. Int J Oncol 2010;36:1261-1267.
-
(2010)
Int J Oncol
, vol.36
, pp. 1261-1267
-
-
Grotegut, S.1
Kappler, R.2
Tarimoradi, S.3
Lehembre, F.4
Christofori, G.5
Von Schweinitz, D.6
-
39
-
-
58949088343
-
Phase I study of paclitaxel with standard dose ifosfamide in children with refractory solid tumors: a Pediatric Oncology Group study (POG 9376)
-
Geller JI, Wall D, Perentesis J, Blaney SM, Bernstein M; Pediatric Oncology Group study 9376. Phase I study of paclitaxel with standard dose ifosfamide in children with refractory solid tumors: a Pediatric Oncology Group study (POG 9376). Pediatr Blood Cancer 2009;52:346-350.
-
(2009)
Pediatr Blood Cancer
, vol.52
, pp. 346-350
-
-
Geller, J.I.1
Wall, D.2
Perentesis, J.3
Blaney, S.M.4
Bernstein, M.5
-
40
-
-
84861638965
-
A high throughput screen identifies Nefopam as targeting cell proliferation in β-catenin driven neoplastic and reactive fibroproliferative disorders
-
Poon R, Hong H, Wei X, Pan J, Alman BA. A high throughput screen identifies Nefopam as targeting cell proliferation in β-catenin driven neoplastic and reactive fibroproliferative disorders. PLoS One 2012;7:e37940.
-
(2012)
PLoS One
, vol.7
-
-
Poon, R.1
Hong, H.2
Wei, X.3
Pan, J.4
Alman, B.A.5
-
41
-
-
84869491003
-
Efficacy of irinotecan single drug treatment in children with refractory or recurrent hepatoblastoma: a phase II trial of the childhood liver tumour strategy group (SIOPEL)
-
Zsíros J, Brugières L, Brock P, Roebuck D, Maibach R, Child M, et al. Efficacy of irinotecan single drug treatment in children with refractory or recurrent hepatoblastoma: a phase II trial of the childhood liver tumour strategy group (SIOPEL). Eur J Cancer 2012;48:3456-3464.
-
(2012)
Eur J Cancer
, vol.48
, pp. 3456-3464
-
-
Zsíros, J.1
Brugières, L.2
Brock, P.3
Roebuck, D.4
Maibach, R.5
Child, M.6
-
42
-
-
34247390662
-
Irinotecan plus temozolomide for relapsed or refractory neuroblastoma
-
Kushner BH, Kramer K, Modak S, Cheung NK. Irinotecan plus temozolomide for relapsed or refractory neuroblastoma. J Clin Oncol 2006;24:5271-5276.
-
(2006)
J Clin Oncol
, vol.24
, pp. 5271-5276
-
-
Kushner, B.H.1
Kramer, K.2
Modak, S.3
Cheung, N.K.4
-
43
-
-
71049179078
-
Irinotecan and temozolomide for Ewing sarcoma: the Memorial Sloan-Kettering experience
-
Casey DA, Wexler LH, Merchant MS, Chou AJ, Merola PR, Price AP, et al. Irinotecan and temozolomide for Ewing sarcoma: the Memorial Sloan-Kettering experience. Pediatr Blood Cancer 2009;53:1029-1034.
-
(2009)
Pediatr Blood Cancer
, vol.53
, pp. 1029-1034
-
-
Casey, D.A.1
Wexler, L.H.2
Merchant, M.S.3
Chou, A.J.4
Merola, P.R.5
Price, A.P.6
-
44
-
-
0033039308
-
Direct translation of a protracted irinotecan schedule from a xenograft model to a phase I trial in children
-
Furman WL, Stewart CF, Poquette CA, Pratt CB, Santana VM, Zamboni WC, et al. Direct translation of a protracted irinotecan schedule from a xenograft model to a phase I trial in children. J Clin Oncol 1999;17:1815-1824.
-
(1999)
J Clin Oncol
, vol.17
, pp. 1815-1824
-
-
Furman, W.L.1
Stewart, C.F.2
Poquette, C.A.3
Pratt, C.B.4
Santana, V.M.5
Zamboni, W.C.6
-
45
-
-
0034892379
-
Clinical pharmacokinetics and metabolism of irinotecan (CPT-11)
-
Mathijssen RHJ, van Alphen RJ, Verweij J, Loos WJ, Nooter K, Stoter G, Sparreboom A. Clinical pharmacokinetics and metabolism of irinotecan (CPT-11). Clin Cancer Res 2001;7:2182-2194.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 2182-2194
-
-
Mathijssen, R.H.J.1
van Alphen, R.J.2
Verweij, J.3
Loos, W.J.4
Nooter, K.5
Stoter, G.6
Sparreboom, A.7
-
46
-
-
84928537682
-
Examining the utility of patient-derived xenograft mouse models
-
Aparicio S, Hidalgo M, Kung AL. Examining the utility of patient-derived xenograft mouse models. Nat Rev Cancer 2015;15:311-316.
-
(2015)
Nat Rev Cancer
, vol.15
, pp. 311-316
-
-
Aparicio, S.1
Hidalgo, M.2
Kung, A.L.3
|