Immobilization of the N-terminal helix stabilizes prefusion paramyxovirus fusion proteins

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 27, 2016, Pages E3844-E3851

  Albert, S Song ^a   Taylor, A Poor ^a   Luciano, A Abriata ^b,c   Theodore, S Jardetzky ^d   Matteo, Dal Peraro ^b,c   Lamb, Robert A ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b EPFL   (Switzerland)

^c SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^d STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN; POLYCLONAL ANTIBODY; VIRUS PROTEIN; VIRUS FUSION PROTEIN;

ARTICLE; CELL SURFACE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; HYDROGEN BOND; HYDROPHOBICITY; LUCIFERASE ASSAY; MOLECULAR DYNAMICS; NEWCASTLE DISEASE VIRUS; NONHUMAN; PARAINFLUENZA VIRUS 5; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN IMMOBILIZATION; PROTEIN REFOLDING; PROTEIN STABILITY; AMINO ACID SUBSTITUTION; ANIMAL; CHLOROCEBUS AETHIOPS; CONFORMATION; METABOLISM; MUTATION; VERO CELL LINE;

AMINO ACID SUBSTITUTION; ANIMALS; CERCOPITHECUS AETHIOPS; MOLECULAR CONFORMATION; MUTATION; PARAINFLUENZA VIRUS 5; PROTEIN STABILITY; VERO CELLS; VIRAL FUSION PROTEINS;

EID: 84977264504     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1608349113     Document Type: Article

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