Membrane fusion machines of paramyxoviruses: Capture of intermediates of fusion

EMBO Journal

Volumn 20, Issue 15, 2001, Pages 4024-4034

  Russell, Charles J ^a   Jardetzky, Theodore S ^a   Lamb, Robert A ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Membrane fusion; Paramyxovirus; Peptide inhibition; Viral entry; Viral fusion glycoprotein

Indexed keywords

HN PROTEIN; PEPTIDE DERIVATIVE; VIRUS FUSION PROTEIN;

ANIMAL CELL; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVATION; MEMBRANE FUSION; NONHUMAN; PARAMYXOVIRUS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN EXPRESSION; RECEPTOR BINDING; TEMPERATURE DEPENDENCE; THERMAL ANALYSIS;

ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; GENE EXPRESSION; HN PROTEIN; HUMANS; MEMBRANE FUSION; RESPIROVIRUS; TEMPERATURE; VERO CELLS; VIRAL FUSION PROTEINS;

EID: 0035421959     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.15.4024     Document Type: Article

References (46)

1. Structural basis for paramyxovirus-mediated membrane fusion
2. Membrane-induced step in the activation of Sendai virus fusion protein
3. Electron microscopy of the human respiratory syncytial virus fusion protein and complexes that it forms with monoclonal antibodies
4. Influenza hemagglutinin is spring-loaded by a metastable native conformation
5. HIV entry and its inhibition
6. Core structure of gp41 from the HIV envelope glycoprotein
7. Evidence that a prominent cavity in the coiled coil of HIV type 1 gp41 is an attractive drug target
8. 2+ and drives membrane fusion
9. An early stage of membrane fusion mediated by the low Ph conformation of influenza hemagglutinin depends upon membrane lipids
10. The pathway of membrane fusion catalyzed by influenza hemagglutinin: Restriction of lipids, hemifusion and lipidic fusion pore formation
11. Crystal structure of the multifunctional paramyxovirus hemagglutinin-neuraminidase
12. Receptor-triggered membrane association of a model retroviral glycoprotein
13. Membrane fusion promoted by increasing surface densities of the paramyxovirus F and HN proteins: Comparison of fusion reactions mediated by simian virus 5 F, human parainfluenza virus type 3 F and influenza virus HA
14. Paramyxovirus fusion (F) protein: A conformational change on cleavage activation
15. Capture of an early fusion-active conformation of HIV-1 gp41
16. Virus-cell and cell-cell fusion
17. Activation of a retroviral membrane fusion protein: Soluble receptor-induced liposome binding of the ALSV envelope glycoprotein
18. Biological activity of paramyxovirus fusion proteins: Factors influencing formation of syncytia
19. Role of a single amino acid at the amino terminus of the simian virus 5 F2 subunit in syncytium formation
20. An amino acid in the heptad repeat 1 domain is important for the haemagglutinin-neuraminidase-independent fusing activity of simian virus 5 fusion protein
21. Membrane fusion and exocytosis
22. A core trimer of the paramyxovirus fusion protein: Parallels to influenza virus hemagglutinin and HIV-1 gp41
23. Paramyxovirus fusion: A hypothesis for changes
24. Paramyxoviridae: The viruses and their replication
25. Evidence that the transition of HIV-1 gp41 into a six-helix bundle, not the bundle configuration, induces membrane fusion
26. Dissociation of gp120 from HIV-1 virions induced by soluble CD4
27. Membrane penetration of Sendai virus glycoproteins during the early stage of fusion with liposomes as determined by hydrophobic affinity labeling
28. Rapid and efficient fusion of phospholipid vesicles by the α-helical core of a SNARE complex in the absence of an N-terminal regulatory domain
29. Fusion protein of the paramyxovirus simian virus 5: Nucleotide sequence of MRNA predicts a highly hydrophobic glycoprotein
30. Expression at the cell surface of biologically active fusion and hemagglutinin-neuraminidase proteins of the paramyxovirus simian virus 5 from cloned CDNA
31. Analysis of the relationship between cleavability of a paramyxovirus fusion protein and length of the connecting peptide
32. Fusion protein of the paramyxovirus SV5: Destabilizing and stabilizing mutants of fusion activation
33. The synaptic SNARE complex is a parallel four-stranded helical bundle
34. Isolation and characterization of monoclonal antibodies to simian virus 5 and their use in revealing antigenic differences between human, canine and simian isolates
35. Conformational changes in the hemagglutinin of influenza virus which accompany heat-induced fusion of virus with liposomes
36. The attachment function of the Newcastle disease virus hemagglutinin-neuraminidase protein can be separated from fusion promotion by mutation
37. A single amino acid change in the Newcastle disease virus fusion protein alters the requirement for HN protein in fusion
38. Coiled coils in both intracellular vesicle and viral membrane fusion
39. Receptor binding and membrane fusion in virus entry: The influenza hemagglutinin
40. Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution
41. Lipid interactions of the hemagglutinin HA2 NH2-terminal segment during influenza virus-induced membrane fusion
42. Atomic structure of the ectodomain from HIV-1 gp41
43. Temperature dependence of fusion by Sendai virus
44. Interaction of peptides with sequences from the Newcastle disease virus fusion protein heptad repeat regions
45. Structural characterization of the human respiratory syncytial virus fusion protein core
46. Proper spacing between heptad repeat B and the transmembrane domain boundary of the paramyxovirus SV5 F protein is critical for biological activity