메뉴 건너뛰기




Volumn 6, Issue , 2016, Pages

Conditional ablation of TGF-β signaling inhibits tumor progression and invasion in an induced mouse bladder cancer model

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN SERINE THREONINE KINASE; TGF-BETA TYPE I RECEPTOR; TGFB1 PROTEIN, MOUSE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84977103924     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep29479     Document Type: Article
Times cited : (48)

References (40)
  • 1
    • 84924271853 scopus 로고    scopus 로고
    • Global cancer statistics, 2012
    • Torre, L. A. et al. Global cancer statistics, 2012. CA Cancer J Clin 65, 87-108, doi: 10.3322/caac.21262 (2015).
    • (2015) CA Cancer J Clin , vol.65 , pp. 87-108
    • Torre, L.A.1
  • 2
    • 84960796740 scopus 로고    scopus 로고
    • Cancer statistics in China, 2015
    • Chen, W. et al. Cancer statistics in China, 2015. CA Cancer J Clin 66, 115-132, doi: 10.3322/caac.21338 (2016).
    • (2016) CA Cancer J Clin , vol.66 , pp. 115-132
    • Chen, W.1
  • 3
    • 84883813935 scopus 로고    scopus 로고
    • EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder: Update 2013
    • Babjuk, M. et al. EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder: update 2013. Eur Urol 64, 639-653, doi: 10.1016/j.eururo.2013.06.003 (2013).
    • (2013) Eur Urol , vol.64 , pp. 639-653
    • Babjuk, M.1
  • 4
    • 67650401369 scopus 로고    scopus 로고
    • Bladder cancer
    • Kaufman, D. S., Shipley, W. U., Feldman, A. S. Bladder cancer. Lancet 374, 239-249, doi: 10.1016/S0140-6736(09)60491-8 (2009).
    • (2009) Lancet , vol.374 , pp. 239-249
    • Kaufman, D.S.1    Shipley, W.U.2    Feldman, A.S.3
  • 6
    • 33846635592 scopus 로고    scopus 로고
    • Muscle-invasive urothelial carcinoma of the bladder
    • Malkowicz, S. B. et al. Muscle-invasive urothelial carcinoma of the bladder. Urology 69, 3-16, doi: 10.1016/j.urology.2006.10.040 (2007).
    • (2007) Urology , vol.69 , pp. 3-16
    • Malkowicz, S.B.1
  • 7
    • 84925545335 scopus 로고    scopus 로고
    • Molecular biology of bladder cancer: New insights into pathogenesis and clinical diversity. Nature reviews
    • Knowles, M. A., Hurst, C. D. Molecular biology of bladder cancer: new insights into pathogenesis and clinical diversity. Nature reviews. Cancer 15, 25-41, doi: 10.1038/nrc3817 (2015).
    • (2015) Cancer , vol.15 , pp. 25-41
    • Knowles, M.A.1    Hurst, C.D.2
  • 9
    • 70450187617 scopus 로고    scopus 로고
    • The regulation of TGFbeta signal transduction
    • Moustakas, A., Heldin, C. H. The regulation of TGFbeta signal transduction. Development 136, 3699-3714, doi: 10.1242/dev.030338 (2009).
    • (2009) Development , vol.136 , pp. 3699-3714
    • Moustakas, A.1    Heldin, C.H.2
  • 10
    • 84857232423 scopus 로고    scopus 로고
    • A portrait of Transforming Growth Factor beta superfamily signalling: Background matters
    • Horbelt, D., Denkis, A., Knaus, P. A portrait of Transforming Growth Factor beta superfamily signalling: Background matters. Int J Biochem Cell Biol 44, 469-474, doi: 10.1016/j.biocel.2011.12.013 (2012).
    • (2012) Int J Biochem Cell Biol , vol.44 , pp. 469-474
    • Horbelt, D.1    Denkis, A.2    Knaus, P.3
  • 11
    • 34247359909 scopus 로고    scopus 로고
    • EMT or apoptosis: A decision for TGF-beta
    • Song, J. EMT or apoptosis: a decision for TGF-beta. Cell Res 17, 289-290, doi: 10.1038/cr.2007.25 (2007).
    • (2007) Cell Res , vol.17 , pp. 289-290
    • Song, J.1
  • 12
    • 0034785348 scopus 로고    scopus 로고
    • TGF-beta signaling in tumor suppression and cancer progression
    • Derynck, R., Akhurst, R. J., Balmain, A. TGF-beta signaling in tumor suppression and cancer progression. Nat Genet 29, 117-129, doi: 10.1038/ng1001-117 (2001).
    • (2001) Nat Genet , vol.29 , pp. 117-129
    • Derynck, R.1    Akhurst, R.J.2    Balmain, A.3
  • 13
    • 84871249546 scopus 로고    scopus 로고
    • Genetic variations in the transforming growth factor beta pathway as predictors of bladder cancer risk
    • Wei, H. et al. Genetic variations in the transforming growth factor beta pathway as predictors of bladder cancer risk. PLoS One 7, e51758, doi: 10.1371/journal.pone.0051758 (2012).
    • (2012) PLoS One , vol.7 , pp. e51758
    • Wei, H.1
  • 14
    • 84896505509 scopus 로고    scopus 로고
    • TGF-beta-induced upregulation of malat1 promotes bladder cancer metastasis by associating with suz12
    • Fan, Y. et al. TGF-beta-induced upregulation of malat1 promotes bladder cancer metastasis by associating with suz12. Clinical cancer research: an official journal of the American Association for Cancer Research 20, 1531-1541, doi: 10.1158/1078-0432.CCR-13-1455 (2014).
    • (2014) Clinical Cancer Research: An Official Journal of the American Association for Cancer Research , vol.20 , pp. 1531-1541
    • Fan, Y.1
  • 15
    • 48249133328 scopus 로고    scopus 로고
    • Molecular credentialing of rodent bladder carcinogenesis models
    • Williams, P. D., Lee, J. K., Theodorescu, D. Molecular credentialing of rodent bladder carcinogenesis models. Neoplasia 10, 838-846 (2008).
    • (2008) Neoplasia , vol.10 , pp. 838-846
    • Williams, P.D.1    Lee, J.K.2    Theodorescu, D.3
  • 16
    • 0015444717 scopus 로고
    • Specific induction of bladder cancer in mice by butyl-(4-hydroxybutyl)-nitrosamine and the effects of hormonal modifications on the sex difference in response
    • Bertram, J. S., Craig, A. W. Specific induction of bladder cancer in mice by butyl-(4-hydroxybutyl)-nitrosamine and the effects of hormonal modifications on the sex difference in response. Eur J Cancer 8, 587-594 (1972).
    • (1972) Eur J Cancer , vol.8 , pp. 587-594
    • Bertram, J.S.1    Craig, A.W.2
  • 17
    • 84919771029 scopus 로고    scopus 로고
    • Bladder cancers arise from distinct urothelial sub-populations
    • 981-985
    • Van Batavia, J. et al. Bladder cancers arise from distinct urothelial sub-populations. Nat Cell Biol 16, 982-991, 981-985, doi: 10.1038/ncb3038 (2014).
    • (2014) Nat Cell Biol , vol.16 , pp. 982-991
    • Van Batavia, J.1
  • 18
    • 58649097517 scopus 로고    scopus 로고
    • Role of Ras signaling in the induction of snail by transforming growth factor-beta
    • Horiguchi, K. et al. Role of Ras signaling in the induction of snail by transforming growth factor-beta. The Journal of biological chemistry 284, 245-253, doi: 10.1074/jbc.M804777200 (2009).
    • (2009) The Journal of Biological Chemistry , vol.284 , pp. 245-253
    • Horiguchi, K.1
  • 19
    • 84922388823 scopus 로고    scopus 로고
    • Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance
    • Kurtova, A. V. et al. Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance. Nature 517, 209-213, doi: 10.1038/nature14034 (2015).
    • (2015) Nature , vol.517 , pp. 209-213
    • Kurtova, A.V.1
  • 20
    • 35348847256 scopus 로고    scopus 로고
    • Transforming growth factor-beta signaling in cancer invasion and metastasis. International journal of cancer
    • Leivonen, S. K., Kahari, V. M. Transforming growth factor-beta signaling in cancer invasion and metastasis. International journal of cancer. Journal international du cancer 121, 2119-2124, doi: 10.1002/ijc.23113 (2007).
    • (2007) Journal International du Cancer , vol.121 , pp. 2119-2124
    • Leivonen, S.K.1    Kahari, V.M.2
  • 21
    • 80051471864 scopus 로고    scopus 로고
    • The specificities of small molecule inhibitors of the TGFss and BMP pathways
    • Vogt, J., Traynor, R., Sapkota, G. P. The specificities of small molecule inhibitors of the TGFss and BMP pathways. Cell Signal 23, 1831-1842, doi: 10.1016/j.cellsig.2011.06.019 (2011).
    • (2011) Cell Signal , vol.23 , pp. 1831-1842
    • Vogt, J.1    Traynor, R.2    Sapkota, G.P.3
  • 22
    • 84863388324 scopus 로고    scopus 로고
    • Dermal beta-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation
    • Chen, D., Jarrell, A., Guo, C., Lang, R., Atit, R. Dermal beta-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation. Development 139, 1522-1533, doi: 10.1242/dev.076463 (2012).
    • (2012) Development , vol.139 , pp. 1522-1533
    • Chen, D.1    Jarrell, A.2    Guo, C.3    Lang, R.4    Atit, R.5
  • 23
    • 84995754137 scopus 로고    scopus 로고
    • Promoter Methylated Tumor Suppressor Genes in Glioma
    • Cheng, Y., Tu, Y., Liang, P. Promoter Methylated Tumor Suppressor Genes in Glioma. Cancer Translational Medicine 1, 8, doi: 10.4103/2395-3977.163803 (2015).
    • (2015) Cancer Translational Medicine , vol.1 , pp. 8
    • Cheng, Y.1    Tu, Y.2    Liang, P.3
  • 24
    • 84995758776 scopus 로고    scopus 로고
    • Galanin is a novel epigenetic silenced functional tumor suppressor in renal cell carcinoma
    • Sun, S., Xu, A., Yang, G., Cheng, Y. Galanin is a novel epigenetic silenced functional tumor suppressor in renal cell carcinoma. Cancer Translational Medicine 1, 5, doi: 10.4103/2395-3977.172861 (2015).
    • (2015) Cancer Translational Medicine , vol.1 , pp. 5
    • Sun, S.1    Xu, A.2    Yang, G.3    Cheng, Y.4
  • 25
    • 84995762566 scopus 로고    scopus 로고
    • Histone H2A and H2B Deubiquitinase in developmental disease and cancer
    • Chen, D., Dai, C., Jiang, Y. Histone H2A and H2B Deubiquitinase in Developmental Disease and Cancer. Cancer Translational Medicine 1, 6, doi: 10.4103/2395-3977.168578 (2015).
    • (2015) Cancer Translational Medicine , vol.1 , pp. 6
    • Chen, D.1    Dai, C.2    Jiang, Y.3
  • 26
    • 70449519162 scopus 로고    scopus 로고
    • Histone deacetylase 4 promotes TGF-beta1-induced synovium-derived stem cell chondrogenesis but inhibits chondrogenically differentiated stem cell hypertrophy
    • Pei, M., Chen, D., Li, J., Wei, L. Histone deacetylase 4 promotes TGF-beta1-induced synovium-derived stem cell chondrogenesis but inhibits chondrogenically differentiated stem cell hypertrophy. Differentiation 78, 260-268, doi: 10.1016/j.diff.2009.08.001 (2009).
    • (2009) Differentiation , vol.78 , pp. 260-268
    • Pei, M.1    Chen, D.2    Li, J.3    Wei, L.4
  • 27
    • 6944225349 scopus 로고    scopus 로고
    • Altered gene expression profile in mouse bladder cancers induced by hydroxybutyl(butyl)nitrosamine
    • Yao, R. et al. Altered gene expression profile in mouse bladder cancers induced by hydroxybutyl(butyl)nitrosamine. Neoplasia 6, 569-577, doi: 10.1593/neo.04223 (2004).
    • (2004) Neoplasia , vol.6 , pp. 569-577
    • Yao, R.1
  • 28
    • 43449101852 scopus 로고    scopus 로고
    • Molecular profiling of bladder cancer: Involvement of the TGF-beta pathway in bladder cancer progression
    • Hung, T. T., Wang, H., Kingsley, E. A., Risbridger, G. P., Russell, P. J. Molecular profiling of bladder cancer: involvement of the TGF-beta pathway in bladder cancer progression. Cancer Lett 265, 27-38, doi: 10.1016/j.canlet.2008.02.034 (2008).
    • (2008) Cancer Lett , vol.265 , pp. 27-38
    • Hung, T.T.1    Wang, H.2    Kingsley, E.A.3    Risbridger, G.P.4    Russell, P.J.5
  • 29
    • 77956190553 scopus 로고    scopus 로고
    • Inhibition of TGF-beta receptor i by siRNA suppresses the motility and invasiveness of T24 bladder cancer cells via modulation of integrins and matrix metalloproteinase
    • Li, Y. et al. Inhibition of TGF-beta receptor I by siRNA suppresses the motility and invasiveness of T24 bladder cancer cells via modulation of integrins and matrix metalloproteinase. International urology and nephrology 42, 315-323, doi: 10.1007/s11255-009-9620-3 (2010).
    • (2010) International Urology and Nephrology , vol.42 , pp. 315-323
    • Li, Y.1
  • 30
    • 84922668738 scopus 로고    scopus 로고
    • Targeting the TGFbeta pathway for cancer therapy
    • Neuzillet, C. et al. Targeting the TGFbeta pathway for cancer therapy. Pharmacology & therapeutics 147, 22-31, doi: 10.1016/j. pharmthera.2014.11.001 (2015).
    • (2015) Pharmacology & Therapeutics , vol.147 , pp. 22-31
    • Neuzillet, C.1
  • 32
    • 0038485575 scopus 로고    scopus 로고
    • TGF-beta1 suppresses apoptosis via differential regulation of MAP kinases and ceramide production
    • Chen, H. H., Zhao, S., Song, J. G. TGF-beta1 suppresses apoptosis via differential regulation of MAP kinases and ceramide production. Cell death and differentiation 10, 516-527, doi: 10.1038/sj.cdd.4401171 (2003).
    • (2003) Cell Death and Differentiation , vol.10 , pp. 516-527
    • Chen, H.H.1    Zhao, S.2    Song, J.G.3
  • 33
    • 85012127345 scopus 로고    scopus 로고
    • Ubiquitin specific peptidase 21 regulates interleukin-8 expression, stem-cell like property of human renal cell carcinoma
    • Peng, L., Hu, Y., Chen, D., Jiao, S., Sun, S. Ubiquitin specific peptidase 21 regulates interleukin-8 expression, stem-cell like property of human renal cell carcinoma. Oncotarget 7, 10, doi: 10.18632/oncotarget.9751 (2016).
    • (2016) Oncotarget , vol.7 , pp. 10
    • Peng, L.1    Hu, Y.2    Chen, D.3    Jiao, S.4    Sun, S.5
  • 34
    • 84923329516 scopus 로고    scopus 로고
    • TGF-beta promotes heterogeneity and drug resistance in squamous cell carcinoma
    • Oshimori, N., Oristian, D., Fuchs, E. TGF-beta promotes heterogeneity and drug resistance in squamous cell carcinoma. Cell 160, 963-976, doi: 10.1016/j.cell.2015.01.043 (2015).
    • (2015) Cell , vol.160 , pp. 963-976
    • Oshimori, N.1    Oristian, D.2    Fuchs, E.3
  • 35
    • 85050578557 scopus 로고    scopus 로고
    • Chinese medicines for prevention and treatment of human hepatocellular carcinoma: Current progress on pharmacological actions and mechanisms
    • Wang, X. et al. Chinese medicines for prevention and treatment of human hepatocellular carcinoma: current progress on pharmacological actions and mechanisms. J Integr Med 13, 142-164, doi: 10.1016/S2095-4964(15)60171-6 (2015).
    • (2015) J Integr Med , vol.13 , pp. 142-164
    • Wang, X.1
  • 36
    • 59449090107 scopus 로고    scopus 로고
    • TGF-beta-induced epithelial to mesenchymal transition
    • Xu, J., Lamouille, S., Derynck, R. TGF-beta-induced epithelial to mesenchymal transition. Cell Res 19, 156-172, doi: 10.1038/cr.2009.5 (2009).
    • (2009) Cell Res , vol.19 , pp. 156-172
    • Xu, J.1    Lamouille, S.2    Derynck, R.3
  • 37
    • 84925228432 scopus 로고    scopus 로고
    • Effect of Saikokeishito, a Kampo medicine, on hydrogen peroxide-induced premature senescence of normal human dermal fibroblasts
    • Takata, T., Motoo, Y., Tomosugi, N. Effect of Saikokeishito, a Kampo medicine, on hydrogen peroxide-induced premature senescence of normal human dermal fibroblasts. J Integr Med 12, 495-503, doi: 10.1016/S2095-4964(14)60052-2 (2014).
    • (2014) J Integr Med , vol.12 , pp. 495-503
    • Takata, T.1    Motoo, Y.2    Tomosugi, N.3
  • 38
    • 84907996793 scopus 로고    scopus 로고
    • Hedgehog signaling restrains bladder cancer progression by eliciting stromal production of urothelial differentiation factors
    • Shin, K. et al. Hedgehog signaling restrains bladder cancer progression by eliciting stromal production of urothelial differentiation factors. Cancer cell 26, 521-533, doi: 10.1016/j.ccell.2014.09.001 (2014).
    • (2014) Cancer Cell , vol.26 , pp. 521-533
    • Shin, K.1
  • 39
    • 84929593738 scopus 로고    scopus 로고
    • The miR-193a-3p-regulated ING5 gene activates the DNA damage response pathway and inhibits multi-chemoresistance in bladder cancer
    • Li, Y. et al. The miR-193a-3p-regulated ING5 gene activates the DNA damage response pathway and inhibits multi-chemoresistance in bladder cancer. Oncotarget 6, 10195-10206 (2015).
    • (2015) Oncotarget , vol.6 , pp. 10195-10206
    • Li, Y.1
  • 40
    • 80055025466 scopus 로고    scopus 로고
    • MAFIP is a tumor suppressor in cervical cancer that inhibits activation of the nuclear factor-kappa B pathway
    • Li, Y. et al. MAFIP is a tumor suppressor in cervical cancer that inhibits activation of the nuclear factor-kappa B pathway. Cancer Sci 102, 2043-2050, doi: 10.1111/j.1349-7006.2011.02061.x (2011).
    • (2011) Cancer Sci , vol.102 , pp. 2043-2050
    • Li, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.