Inhibition of TGF-β receptor i by siRNA suppresses the motility and invasiveness of T24 bladder cancer cells via modulation of integrins and matrix metalloproteinase

International Urology and Nephrology

Volumn 42, Issue 2, 2010, Pages 315-323

  Li, Yubing ^a   Yang, Kai ^a   Mao, Qiqi ^a   Zheng, Xiangyi ^a   Kong, Debo ^a   Xie, Liping ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Bladder cancer; Invasion cell motility; RNA interference (RNAi); TGF type I receptor (TGFBRI); Transforming growth factor 1 (TGF 1)

Indexed keywords

ALPHA INTEGRIN; BETA1 INTEGRIN; BETA2 INTEGRIN; GELATINASE B; INTEGRIN; LIPOSOME; MATRIGEL; MATRIX METALLOPROTEINASE; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BLADDER CARCINOGENESIS; BLADDER CARCINOMA; CANCER CELL; CANCER GROWTH; CANCER INVASION; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME REGULATION; GENE EXPRESSION REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; LIPOSOMAL DELIVERY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS INHIBITION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

CARCINOMA, TRANSITIONAL CELL; CELL MOVEMENT; DOWN-REGULATION; HUMANS; INTEGRINS; MATRIX METALLOPROTEINASES; NEOPLASM INVASIVENESS; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; URINARY BLADDER NEOPLASMS;

EID: 77956190553     PISSN: 03011623     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11255-009-9620-3     Document Type: Article

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