Multiple chimeric antigen receptors successfully target chondroitin sulfate proteoglycan 4 in several different cancer histologies and cancer stem cells

Journal for ImmunoTherapy of Cancer

Volumn 2, Issue 1, 2014, Pages

  Beard, Rachel E ^a   Zheng, Zhili ^a   Lagisetty, Kiran H ^a   Burns, William R ^a   Tran, Eric ^a   Hewitt, Stephen M ^a   Abate Daga, Daniel ^a   Rosati, Shannon F ^a   Fine, Howard A ^b   Ferrone, Soldano ^c   Rosenberg, Steven A ^a   Morgan, Richard A ^a,d  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d BLUEBIRD BIO   (United States)

Author keywords

Cancer stem cells; Chimeric antigen receptor; CSPG4; Glioblastoma; Immunotherapy; Melanoma

Indexed keywords

CHIMERIC ANTIGEN RECEPTOR; CYTOKINE; PROTEOCHONDROITIN SULFATE; PROTEOCHONDROITIN SULFATE 4; RETROVIRUS VECTOR; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER CELL LINE; CANCER IMMUNOTHERAPY; CANCER STEM CELL; CONTROLLED STUDY; CYTOLYSIS; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GENETIC ANALYSIS; GLIOBLASTOMA CELL LINE; GLIOBLASTOMA STEM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MELANOMA CELL LINE; NEOPLASM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MICROARRAY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SIGNAL TRANSDUCTION;

EID: 84977097883     PISSN: None     EISSN: 20511426     Source Type: Journal    
DOI: 10.1186/2051-1426-2-25     Document Type: Article

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