Clinical features of TBK1 carriers compared with C9orf72, GRN and non-mutation carriers in a Belgian cohort

Brain

Volumn 139, Issue 2, 2016, Pages 452-467

  Van Mossevelde, Sara ^a,b,c,d   Van Der Zee, Julie ^a,b   Gijselinck, Ilse ^a,b   Engelborghs, Sebastiaan ^b,c   Sieben, Anne ^a,b,e   Van Langenhove, Tim ^a,b,d   De Bleecker, Jan ^e   Baets, Jonathan ^a,b,d   Vandenbulcke, Mathieu ^f,g   Van Laere, Koen ^f   Ceyssens, Sarah ^a,d   Van Den Broeck, Marleen ^a,b   Peeters, Karin ^a,b   Mattheijssens, Maria ^a,b   Cras, Patrick ^b,d   Vandenberghe, Rik ^f,g   De Jonghe, Peter ^a,b,d   Martin, Jean Jacques ^b   De Deyn, Peter P ^b,c   Cruts, Marc ^a,b   Van Broeckhoven, Christine ^a,b   Nuytten, Dirk ^h   Smets, Katrien ^d   Robberecht, Wim ^g   Van Damme, Philip ^g   Santens, Patrick ^e   Dermaut, Bart ^e   Deryck, Olivier ⁱ   Bergmans, Bruno ⁱ   Delbeck, Jean ^j   Versijpt, Jan ^k   Michotte, Alex ^k   Willems, Christiana ^l   Ivanoiu, Adrian ^m   Salmon, Eric ⁿ   more..

^a UNIVERSITY OF ANTWERP   (Belgium)

^b UNIVERSITY OF ANTWERP   (Belgium)

^c Memory Clinic   (Belgium)

^d ANTWERP UNIVERSITY HOSPITAL   (Belgium)

^e GHENT UNIVERSITY HOSPITAL   (Belgium)

^f UNIVERSITY OF LEUVEN   (Belgium)

^g UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^h Hospital Network Antwerp   (Belgium)

ⁱ General Hospital St Jan   (Belgium)

^j General Hospital Sint Maria   (Germany)

^k UNIVERSITY HOSPITAL BRUSSELS   (Belgium)

^l JESSA HOSPITAL   (Belgium)

^m CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

ⁿ UNIVERSITY OF LIÈGE   (Belgium)

more..

Author keywords

amyotrophic lateral sclerosis; C9orf72; frontotemporal lobar degeneration; genotype phenotype correlations; TBK1

Indexed keywords

FLUORODEOXYGLUCOSE F 18; C9ORF72 PROTEIN, HUMAN; GRN PROTEIN, HUMAN; PROTEIN; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE; TBK1 PROTEIN, HUMAN;

ADULT; AGED; AMNESIA; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BEHAVIOR DISORDER; BELGIAN; BRAIN PERFUSION; C9ORF72 GENE; CLINICAL ARTICLE; CLINICAL FEATURE; COGNITIVE DEFECT; CONTROLLED STUDY; DEMENTIA; DISEASE DURATION; EXTRAPYRAMIDAL SYMPTOM; FEMALE; FRONTOTEMPORAL DEMENTIA; GENE; GENE EXPRESSION; GENE MUTATION; GENOTYPE PHENOTYPE CORRELATION; GRN GENE; HETEROZYGOTE; HUMAN; HUMAN TISSUE; LANGUAGE DISABILITY; LOSS OF FUNCTION MUTATION; MALE; MOTOR NEURON DISEASE; NEUROIMAGING; NEUROPATHOLOGY; ONSET AGE; PHENOTYPE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TANK BINDING KINASE 1 GENE; BELGIUM; COHORT ANALYSIS; COMPARATIVE STUDY; GENETICS; MIDDLE AGED; MUTATION; PEDIGREE;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; BELGIUM; COHORT STUDIES; FEMALE; FRONTOTEMPORAL DEMENTIA; HETEROZYGOTE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MIDDLE AGED; MUTATION; PEDIGREE; PROTEIN-SERINE-THREONINE KINASES; PROTEINS;

EID: 84976905423     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awv358     Document Type: Article

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