Loss of TBK1 is a frequent cause of frontotemporal dementia in a Belgian cohort

Neurology

Volumn 85, Issue 24, 2015, Pages 2116-2125

  Gijselinck, Ilse ^a,b   Van Mossevelde, Sara ^a,b   Van Der Zee, Julie ^a,b   Sieben, Anne ^a,b,c   Philtjens, Stéphanie ^a,b   Heeman, Bavo ^a,b   Engelborghs, Sebastiaan ^b,d   Vandenbulcke, Mathieu ^e,g   De Baets, Greet ^a   Bäumer, Veerle ^a,b   Cuijt, Ivy ^a,b   Van Den Broeck, Marleen ^a,b   Peeters, Karin ^a,b   Mattheijssens, Maria ^a,b   Rousseau, Frederic ^a   Vandenberghe, Rik ^f,g   De Jonghe, Peter ^a,b,h   Cras, Patrick ^b,h   De Deyn, Peter P ^b,d,i   Martin, Jean Jacques ^b   Cruts, Marc ^a,b   Van Broeckhoven, Christine ^a,b   more..

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b UNIVERSITY OF ANTWERP   (Belgium)

^c GHENT UNIVERSITY HOSPITAL   (Belgium)

^d Hospital Network Antwerp Middelheim and Hoge Beuken   (Belgium)

^e Brain and Emotion Laboratory   (Netherlands)

^f UNIVERSITY OF LEUVEN   (Belgium)

^g UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^h ANTWERP UNIVERSITY HOSPITAL   (Belgium)

ⁱ UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BELGIAN; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; FRAMESHIFT MUTATION; FRONTOTEMPORAL DEMENTIA; GENE; GENE LOSS; GENE SEQUENCE; GENOTYPE PHENOTYPE CORRELATION; HUMAN; IMMUNOHISTOCHEMISTRY; LOSS OF FUNCTION MUTATION; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MISSENSE MUTATION; MUTATIONAL ANALYSIS; NEUROPATHOLOGY; NONSENSE MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TBK1 GENE; BELGIUM; DEFICIENCY; GENETICS; MUTATION; PEDIGREE; VERY ELDERLY;

PROTEIN SERINE THREONINE KINASE; TBK1 PROTEIN, HUMAN;

ADULT; AGED; AGED, 80 AND OVER; BELGIUM; COHORT STUDIES; FEMALE; FRONTOTEMPORAL DEMENTIA; HUMANS; MALE; MIDDLE AGED; MUTATION; PEDIGREE; PROTEIN-SERINE-THREONINE KINASES;

EID: 84951320438     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0000000000002220     Document Type: Article

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