-
1
-
-
33748192942
-
The Myc oncoprotein as a therapeutic target for human cancer
-
Vita M, Henriksson M. The Myc oncoprotein as a therapeutic target for human cancer. Semin Cancer Biol 2006;16:318-30.
-
(2006)
Semin Cancer Biol
, vol.16
, pp. 318-330
-
-
Vita, M.1
Henriksson, M.2
-
2
-
-
84887147170
-
MYC activation is a hallmark of cancer initiation and maintenance
-
Gabay M, Li Y, Felsher DW. MYC activation is a hallmark of cancer initiation and maintenance. Cold Spring Harb Perspect Med 2014;4:pii:a014241.
-
(2014)
Cold Spring Harb Perspect Med
, vol.4
-
-
Gabay, M.1
Li, Y.2
Felsher, D.W.3
-
3
-
-
84867021989
-
Transcriptional amplification in tumor cells with elevated c-Myc
-
Lin CY, Loven J, Rahl PB, Paranal RM, Burge CB, Bradner JE, et al. Transcriptional amplification in tumor cells with elevated c-Myc. Cell 2012;151:56-67.
-
(2012)
Cell
, vol.151
, pp. 56-67
-
-
Lin, C.Y.1
Loven, J.2
Rahl, P.B.3
Paranal, R.M.4
Burge, C.B.5
Bradner, J.E.6
-
4
-
-
84867010006
-
c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells
-
Nie Z, Hu G, Wei G, Cui K, Yamane A, Resch W, et al. c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells. Cell 2012;151:68-79.
-
(2012)
Cell
, vol.151
, pp. 68-79
-
-
Nie, Z.1
Hu, G.2
Wei, G.3
Cui, K.4
Yamane, A.5
Resch, W.6
-
5
-
-
84904785973
-
Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis
-
Sabo A, Kress TR, Pelizzola M, de Pretis S, Gorski MM, Tesi A, et al. Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis. Nature 2014;511:488-92.
-
(2014)
Nature
, vol.511
, pp. 488-492
-
-
Sabo, A.1
Kress, T.R.2
Pelizzola, M.3
De Pretis, S.4
Gorski, M.M.5
Tesi, A.6
-
6
-
-
84904823447
-
Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles
-
Walz S, Lorenzin F, Morton J, Wiese KE, von Eyss B, Herold S, et al. Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles. Nature 2014;511:483-7.
-
(2014)
Nature
, vol.511
, pp. 483-487
-
-
Walz, S.1
Lorenzin, F.2
Morton, J.3
Wiese, K.E.4
Von Eyss, B.5
Herold, S.6
-
7
-
-
84964695696
-
Sequence specificity incompletely defines the genome-wide occupancy of Myc
-
Guo J, Li T, Schipper J, Nilson KA, Fordjour FK, Cooper JJ, et al. Sequence specificity incompletely defines the genome-wide occupancy of Myc. Genome Biol 2014;15:482.
-
(2014)
Genome Biol
, vol.15
, pp. 482
-
-
Guo, J.1
Li, T.2
Schipper, J.3
Nilson, K.A.4
Fordjour, F.K.5
Cooper, J.J.6
-
8
-
-
84942370919
-
MYC: Connecting selective transcriptional control to global RNA production
-
Kress TR, Sabo A, Amati B. MYC: connecting selective transcriptional control to global RNA production. Nat Rev Cancer 2015;15:593-607.
-
(2015)
Nat Rev Cancer
, vol.15
, pp. 593-607
-
-
Kress, T.R.1
Sabo, A.2
Amati, B.3
-
9
-
-
59649128301
-
A positive role for Myc in TGFbeta-induced Snail transcription and epithelial-to-mesenchymal transition
-
Smith AP, Verrecchia A, Faga G, Doni M, Perna D, Martinato F, et al. A positive role for Myc in TGFbeta-induced Snail transcription and epithelial-to-mesenchymal transition. Oncogene 2009;28:422-30.
-
(2009)
Oncogene
, vol.28
, pp. 422-430
-
-
Smith, A.P.1
Verrecchia, A.2
Faga, G.3
Doni, M.4
Perna, D.5
Martinato, F.6
-
11
-
-
0027533679
-
Oncogenic activity of the c-Myc protein requires dimerization with Max
-
Amati B, Brooks MW, Levy N, Littlewood TD, Evan GI, Land H. Oncogenic activity of the c-Myc protein requires dimerization with Max. Cell 1993;72:233-45.
-
(1993)
Cell
, vol.72
, pp. 233-245
-
-
Amati, B.1
Brooks, M.W.2
Levy, N.3
Littlewood, T.D.4
Evan, G.I.5
Land, H.6
-
12
-
-
0025166030
-
An amino-terminal c-myc domain required for neoplastic transformation activates transcription
-
Kato GJ, Barrett J, Villa-Garcia M, Dang CV. An amino-terminal c-myc domain required for neoplastic transformation activates transcription. Mol Cell Biol 1990;10:5914-20.
-
(1990)
Mol Cell Biol
, vol.10
, pp. 5914-5920
-
-
Kato, G.J.1
Barrett, J.2
Villa-Garcia, M.3
Dang, C.V.4
-
13
-
-
84936857771
-
Myc and its interactors take shape
-
Tu WB, Helander S, Pilstal R, Hickman KA, Lourenco C, Jurisica I, et al. Myc and its interactors take shape. Biochim Biophys Acta 2015;1849:469-83.
-
(2015)
Biochim Biophys Acta
, vol.1849
, pp. 469-483
-
-
Tu, W.B.1
Helander, S.2
Pilstal, R.3
Hickman, K.A.4
Lourenco, C.5
Jurisica, I.6
-
14
-
-
3543028648
-
Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins
-
Bouchard C, Marquardt J, Bras A, Medema RH, Eilers M. Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins. EMBO J 2004;23:2830-40.
-
(2004)
EMBO J
, vol.23
, pp. 2830-2840
-
-
Bouchard, C.1
Marquardt, J.2
Bras, A.3
Medema, R.H.4
Eilers, M.5
-
15
-
-
77951920690
-
c-Myc regulates transcriptional pause release
-
Rahl PB, Lin CY, Seila AC, Flynn RA, McCuine S, Burge CB, et al. c-Myc regulates transcriptional pause release. Cell 2010;141:432-45.
-
(2010)
Cell
, vol.141
, pp. 432-445
-
-
Rahl, P.B.1
Lin, C.Y.2
Seila, A.C.3
Flynn, R.A.4
McCuine, S.5
Burge, C.B.6
-
17
-
-
0029912395
-
A link between c-Myc-mediated transcriptional repression and neoplastic transformation
-
Lee LA, Dolde C, Barrett J, Wu CS, Dang CV. A link between c-Myc-mediated transcriptional repression and neoplastic transformation. J Clin Invest 1996;97:1687-95.
-
(1996)
J Clin Invest
, vol.97
, pp. 1687-1695
-
-
Lee, L.A.1
Dolde, C.2
Barrett, J.3
Wu, C.S.4
Dang, C.V.5
-
18
-
-
84931566688
-
Repression of SRF target genes is critical for Myc-dependent apoptosis of epithelial cells
-
Wiese KE, Haikala HM, von Eyss B, Wolf E, Esnault C, Rosenwald A, et al. Repression of SRF target genes is critical for Myc-dependent apoptosis of epithelial cells. EMBO J 2015;34:1554-71.
-
(2015)
EMBO J
, vol.34
, pp. 1554-1571
-
-
Wiese, K.E.1
Haikala, H.M.2
Von Eyss, B.3
Wolf, E.4
Esnault, C.5
Rosenwald, A.6
-
19
-
-
77953917870
-
The interaction between Myc and Miz1 is required to antagonize TGFbeta-dependent autocrine signaling during lymphoma formation and maintenance
-
van Riggelen J, Muller J, Otto T, Beuger V, Yetil A, Choi PS, et al. The interaction between Myc and Miz1 is required to antagonize TGFbeta-dependent autocrine signaling during lymphoma formation and maintenance. Genes Dev 2010;24:1281-94.
-
(2010)
Genes Dev
, vol.24
, pp. 1281-1294
-
-
Van Riggelen, J.1
Muller, J.2
Otto, T.3
Beuger, V.4
Yetil, A.5
Choi, P.S.6
-
20
-
-
84958787563
-
The interaction of Myc with Miz1 defines medulloblastoma subgroup identity
-
Vo BT, Wolf E, Kawauchi D, Gebhardt A, Rehg JE, Finkelstein D, et al. The interaction of Myc with Miz1 defines medulloblastoma subgroup identity. Cancer Cell 2016;29:5-16.
-
(2016)
Cancer Cell
, vol.29
, pp. 5-16
-
-
Vo, B.T.1
Wolf, E.2
Kawauchi, D.3
Gebhardt, A.4
Rehg, J.E.5
Finkelstein, D.6
-
21
-
-
84943257841
-
MYC, metabolism, and Cancer
-
Stine ZE, Walton ZE, Altman BJ, Hsieh AL, Dang CV. MYC, metabolism, and Cancer. Cancer Discov 2015;5:1024-39.
-
(2015)
Cancer Discov
, vol.5
, pp. 1024-1039
-
-
Stine, Z.E.1
Walton, Z.E.2
Altman, B.J.3
Hsieh, A.L.4
Dang, C.V.5
-
22
-
-
20044394527
-
Developmental context determines latency of MYC-induced tumorigenesis
-
Beer S, Zetterberg A, Ihrie RA, McTaggart RA, Yang Q, Bradon N, et al. Developmental context determines latency of MYC-induced tumorigenesis. PLoS Biol 2004;2:e332.
-
(2004)
PLoS Biol
, vol.2
, pp. e332
-
-
Beer, S.1
Zetterberg, A.2
Ihrie, R.A.3
McTaggart, R.A.4
Yang, Q.5
Bradon, N.6
-
23
-
-
7744220635
-
MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer
-
Shachaf CM, Kopelman AM, Arvanitis C, Karlsson A, Beer S, Mandl S, et al. MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer. Nature 2004;431:1112-7.
-
(2004)
Nature
, vol.431
, pp. 1112-1117
-
-
Shachaf, C.M.1
Kopelman, A.M.2
Arvanitis, C.3
Karlsson, A.4
Beer, S.5
Mandl, S.6
-
24
-
-
84958787563
-
The interaction of Myc with Miz1 defines medulloblastoma subgroup identity
-
Vo BT, Wolf E, Kawauchi D, Gebhardt A, Rehg JE, Finkelstein D, et al. The interaction of Myc with Miz1 defines medulloblastoma subgroup identity. Cancer Cell 2016;29:5-16.
-
(2016)
Cancer Cell
, vol.29
, pp. 5-16
-
-
Vo, B.T.1
Wolf, E.2
Kawauchi, D.3
Gebhardt, A.4
Rehg, J.E.5
Finkelstein, D.6
-
25
-
-
84860389417
-
Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts
-
Perna D, Faga G, Verrecchia A, Gorski MM, Barozzi I, Narang V, et al. Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts. Oncogene 2012;31:1695-709.
-
(2012)
Oncogene
, vol.31
, pp. 1695-1709
-
-
Perna, D.1
Faga, G.2
Verrecchia, A.3
Gorski, M.M.4
Barozzi, I.5
Narang, V.6
-
26
-
-
0035856918
-
c-Myc regulates mammalian body size by controlling cell number but not cell size
-
Trumpp A, Refaeli Y, Oskarsson T, Gasser S, Murphy M, Martin GR, et al. c-Myc regulates mammalian body size by controlling cell number but not cell size. Nature 2001;414:768-73.
-
(2001)
Nature
, vol.414
, pp. 768-773
-
-
Trumpp, A.1
Refaeli, Y.2
Oskarsson, T.3
Gasser, S.4
Murphy, M.5
Martin, G.R.6
-
27
-
-
57049182539
-
Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer
-
Cairo S, Armengol C, De Reynies A, Wei Y, Thomas E, Renard CA, et al. Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer. Cancer Cell 2008;14:471-84.
-
(2008)
Cancer Cell
, vol.14
, pp. 471-484
-
-
Cairo, S.1
Armengol, C.2
De Reynies, A.3
Wei, Y.4
Thomas, E.5
Renard, C.A.6
-
28
-
-
33746441453
-
Generation and analysis of genetically defined liver carcinomas derived from bipotential liver progenitors
-
Zender L, Xue W, Cordon-Cardo C, Hannon GJ, Lucito R, Powers S, et al. Generation and analysis of genetically defined liver carcinomas derived from bipotential liver progenitors. Cold Spring Harb Symp Quant Biol 2005;70:251-61.
-
(2005)
Cold Spring Harb Symp Quant Biol
, vol.70
, pp. 251-261
-
-
Zender, L.1
Xue, W.2
Cordon-Cardo, C.3
Hannon, G.J.4
Lucito, R.5
Powers, S.6
-
29
-
-
18644371442
-
Negative regulation of the mammalian UV response by Myc through association with Miz-1
-
Herold S, Wanzel M, Beuger V, Frohme C, Beul D, Hillukkala T, et al. Negative regulation of the mammalian UV response by Myc through association with Miz-1. Mol Cell 2002;10:509-21.
-
(2002)
Mol Cell
, vol.10
, pp. 509-521
-
-
Herold, S.1
Wanzel, M.2
Beuger, V.3
Frohme, C.4
Beul, D.5
Hillukkala, T.6
-
30
-
-
79952828836
-
Transcriptional repression: The dark side of myc
-
Herkert B, Eilers M. Transcriptional repression: the dark side of myc. Genes Cancer 2010;1:580-6.
-
(2010)
Genes Cancer
, vol.1
, pp. 580-586
-
-
Herkert, B.1
Eilers, M.2
-
31
-
-
29944444852
-
Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1
-
Gebhardt A, Frye M, Herold S, Benitah SA, Braun K, Samans B, et al. Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1. J Cell Biol 2006;172:139-49.
-
(2006)
J Cell Biol
, vol.172
, pp. 139-149
-
-
Gebhardt, A.1
Frye, M.2
Herold, S.3
Benitah, S.A.4
Braun, K.5
Samans, B.6
-
32
-
-
56649107917
-
Analysis of Myc-induced histone modifications on target chromatin
-
Martinato F, Cesaroni M, Amati B, Guccione E. Analysis of Myc-induced histone modifications on target chromatin. PLoS One 2008;3:e3650.
-
(2008)
PLoS One
, vol.3
-
-
Martinato, F.1
Cesaroni, M.2
Amati, B.3
Guccione, E.4
-
33
-
-
36549013619
-
RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo
-
Zeitlinger J, Stark A, Kellis M, Hong JW, Nechaev S, Adelman K, et al. RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo. Nat Genet 2007;39:1512-6.
-
(2007)
Nat Genet
, vol.39
, pp. 1512-1516
-
-
Zeitlinger, J.1
Stark, A.2
Kellis, M.3
Hong, J.W.4
Nechaev, S.5
Adelman, K.6
-
34
-
-
84923780299
-
Getting up to speed with transcription elongation by RNA polymerase II
-
Jonkers I, Lis JT. Getting up to speed with transcription elongation by RNA polymerase II. Nat Rev Mol Cell Biol 2015;16:167-77.
-
(2015)
Nat Rev Mol Cell Biol
, vol.16
, pp. 167-177
-
-
Jonkers, I.1
Lis, J.T.2
-
35
-
-
79960006190
-
13C-pyruvate imaging reveals alterations in glycolysis that precede c-Myc-induced tumor formation and regression
-
Hu S, Balakrishnan A, Bok RA, Anderton B, Larson PE, Nelson SJ, et al. 13C-pyruvate imaging reveals alterations in glycolysis that precede c-Myc-induced tumor formation and regression. Cell Metab 2011;14:131-42.
-
(2011)
Cell Metab
, vol.14
, pp. 131-142
-
-
Hu, S.1
Balakrishnan, A.2
Bok, R.A.3
Anderton, B.4
Larson, P.E.5
Nelson, S.J.6
-
36
-
-
84960842480
-
MYC regulates the antitumor immune response through CD47 and PD-L1
-
Mar 10. [Epub ahead of print]
-
Casey SC, Tong L, Li Y, Do R, Walz S, Fitzgerald KN, et al. MYC regulates the antitumor immune response through CD47 and PD-L1. Science. 2016 Mar 10. [Epub ahead of print].
-
(2016)
Science
-
-
Casey, S.C.1
Tong, L.2
Li, Y.3
Do, R.4
Walz, S.5
Fitzgerald, K.N.6
|