Myc and mRNA capping

Biochimica et Biophysica Acta - Gene Regulatory Mechanisms

Volumn 1849, Issue 5, 2015, Pages 501-505

  Dunn, Sianadh ^a   Cowling, Victoria H ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

7 methylguanosine; C Myc; Capping; MRNA; Transcription

Indexed keywords

7-METHYLGUANOSINE; GUANOSINE; MESSENGER RNA; MYC PROTEIN; RNA POLYMERASE II;

ANALOGS AND DERIVATIVES; BIOSYNTHESIS; CELL PROLIFERATION; GENE EXPRESSION REGULATION; GENETICS; HUMAN; NEOPLASM; PATHOLOGY; PROTEIN SYNTHESIS;

CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GUANOSINE; HUMANS; NEOPLASMS; PROTEIN BIOSYNTHESIS; PROTO-ONCOGENE PROTEINS C-MYC; RNA POLYMERASE II; RNA, MESSENGER;

EID: 84897355779     PISSN: 18749399     EISSN: 18764320     Source Type: Journal    
DOI: 10.1016/j.bbagrm.2014.03.007     Document Type: Review

References (63)

1. Meyer N., Penn L.Z. Reflecting on 25years with MYC. Nat. Rev. Cancer 2008, 8(12):976-990.
2. Eilers M., Eisenman R.N. Myc's broad reach. Genes Dev. 2008, 22(20):2755-2766.
3. Dang C.V. MYC on the path to cancer. Cell 2012, 149(1):22-35.
4. Hann S.R., Abrams H.D., Rohrschneider L.R., Eisenman R.N. Proteins encoded by v-myc and c-myc oncogenes: identification and localization in acute leukemia virus transformants and bursal lymphoma cell lines. Cell 1983, 34(3):789-798.
5. Cowling V.H., Cole M.D. Mechanism of transcriptional activation by the Myc oncoproteins. Semin. Cancer Biol. 2006, 16(4):242-252.
6. Blackwood E.M., Eisenman R.N. Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc. Science 1991, 251(4998):1211-1217.
7. Amati B., Brooks M.W., Levy N., Littlewood T.D., Evan G.I., Land H. Oncogenic activity of the c-Myc protein requires dimerization with Max. Cell 1993, 72(2):233-245.
8. Patel J.H., Loboda A.P., Showe M.K., Showe L.C., McMahon S.B. Analysis of genomic targets reveals complex functions of MYC. Nat. Rev. Cancer 2004, 4(7):562-568.
9. Eberhardy S.R., Farnham P.J. c-Myc mediates activation of the cad promoter via a post-RNA polymerase II recruitment mechanism. J. Biol. Chem. 2001, 276(51):48562-48571.
10. Eberhardy S.R., Farnham P.J. Myc recruits P-TEFb to mediate the final step in the transcriptional activation of the cad promoter. J. Biol. Chem. 2002, 277(42):40156-40162.
11. Moore M.J., Proudfoot N.J. Pre-mRNA processing reaches back to transcription and ahead to translation. Cell 2009, 136(4):688-700.
12. Chapman R.D., Heidemann M., Hintermair C., Eick D. Molecular evolution of the RNA polymerase II CTD. Trends Genet. 2008, 24(6):289-296.
13. Knoepfler P.S., Zhang X.Y., Cheng P.F., Gafken P.R., McMahon S.B., Eisenman R.N. Myc influences global chromatin structure. EMBO J. 2006, 25(12):2723-2734.
14. Cowling V.H., Cole M.D. The Myc transactivation domain promotes global phosphorylation of the RNA polymerase II carboxy-terminal domain independently of direct DNA binding. Mol. Cell. Biol. 2007, 27(6):2059-2073.
15. Lin C.Y., Loven J., Rahl P.B., Paranal R.M., Burge C.B., Bradner J.E., Lee T.I., Young R.A. Transcriptional amplification in tumor cells with elevated c-Myc. Cell 2012, 151(1):56-67.
16. Nie Z., Hu G., Wei G., Cui K., Yamane A., Resch W., Wang R., Green D.R., Tessarollo L., Casellas R., Zhao K., Levens D. c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells. Cell 2012, 151(1):68-79.
17. Gomez-Roman N., Grandori C., Eisenman R.N., White R.J. Direct activation of RNA polymerase III transcription by c-Myc. Nature 2003, 421(6920):290-294.
18. Grandori C., Gomez-Roman N., Felton-Edkins Z.A., Ngouenet C., Galloway D.A., Eisenman R.N., White R.J. c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I. Nat. Cell Biol. 2005, 7(3):311-318.
19. Grewal S.S., Li L., Orian A., Eisenman R.N., Edgar B.A. Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development. Nat. Cell Biol. 2005, 7(3):295-302.
20. Arabi A., Wu S., Ridderstrale K., Bierhoff H., Shiue C., Fatyol K., Fahlen S., Hydbring P., Soderberg O., Grummt I., Larsson L.G., Wright A.P. c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription. Nat. Cell Biol. 2005, 7(3):303-310.
21. Shatkin A.J. Capping of eucaryotic mRNAs. Cell 1976, 9(4 PT 2):645-653.
22. Furuichi Y., Shatkin A.J. Viral and cellular mRNA capping: past and prospects. Adv. Virus Res. 2000, 55:135-184.
23. Cowling V.H. Regulation of mRNA cap methylation. Biochem. J. 2009, 425(2):295-302.
24. Gonatopoulos-Pournatzis T., Cowling V.H. The cap binding complex. The Biochemical journal 2013, 457(Part 2).
25. Topisirovic I., Svitkin Y.V., Sonenberg N., Shatkin A.J. Cap and cap-binding proteins in the control of gene expression. Wiley Interdiscip. Rev. RNA 2011, 2(2):277-298.
26. Shuman S. What messenger RNA capping tells us about eukaryotic evolution. Nat. Rev. Mol. Cell Biol. 2002, 3(8):619-625.
27. Yue Z., Maldonado E., Pillutla R., Cho H., Reinberg D., Shatkin A.J. Mammalian capping enzyme complements mutant Saccharomyces cerevisiae lacking mRNA guanylyltransferase and selectively binds the elongating form of RNA polymerase II. Proc. Natl. Acad. Sci. U. S. A. 1997, 94(24):12898-12903.
28. Yamada-Okabe T., Doi R., Shimmi O., Arisawa M., Yamada-Okabe H. Isolation and characterization of a human cDNA for mRNA 5'-capping enzyme. Nucleic Acids Res. 1998, 26(7):1700-1706.
29. Pillutla R.C., Shimamoto A., Furuichi Y., Shatkin A.J. Human mRNA capping enzyme (RNGTT) and cap methyltransferase (RNMT) map to 6q16 and 18p11.22-p11.23, respectively. Genomics 1998, 54(2):351-353.
30. Tsukamoto T., Shibagaki Y., Niikura Y., Mizumoto K. Cloning and characterization of three human cDNAs encoding mRNA (guanine-7-)-methyltransferase, an mRNA cap methylase. Biochem. Biophys. Res. Commun. 1998, 251(1):27-34.
31. Gonatopoulos-Pournatzis T., Dunn S., Bounds R., Cowling V.H. RAM/Fam103a1 Is Required for mRNA cap methylation. Mol. Cell 2011, 44(4):585-596.
32. Gonatopoulos-Pournatzis T., Cowling V.H. RAM function is dependent on Kapbeta2-mediated nuclear entry. Biochem. J. 2014, 457(3):473-484.
33. Werner M., Purta E., Kaminska K.H., Cymerman I.A., Campbell D.A., Mittra B., Zamudio J.R., Sturm N.R., Jaworski J., Bujnicki J.M. 2'-O-ribose methylation of cap2 in human: function and evolution in a horizontally mobile family. Nucleic Acids Res. 2011, 39(11):4756-4768.
34. Belanger F., Stepinski J., Darzynkiewicz E., Pelletier J. Characterization of hMTr1, a human Cap1 2'-O-ribose methyltransferase. J. Biol. Chem. 2010, 285(43):33037-33044.
35. Li Y., Kiledjian M. Regulation of mRNA decapping. Wiley Interdiscip. Rev. RNA 2010, 1(2):253-265.
36. Liu H., Kiledjian M. Decapping the message: a beginning or an end. Biochem. Soc. Trans. 2006, 34(Pt 1):35-38.
37. Arribas-Layton M., Wu D., Lykke-Andersen J., Song H. Structural and functional control of the eukaryotic mRNA decapping machinery. Biochim. Biophys. Acta 2013, 1829(6-7):580-589.
38. Furuichi Y., LaFiandra A., Shatkin A.J. 5'-terminal structure and mRNA stability. Nature 1977, 266(5599):235-239.
39. Brannan K., Kim H., Erickson B., Glover-Cutter K., Kim S., Fong N., Kiemele L., Hansen K., Davis R., Lykke-Andersen J., Bentley D.L. mRNA decapping factors and the exonuclease Xrn2 function in widespread premature termination of RNA polymerase II transcription. Mol. Cell 2012, 46(3):311-324.
40. Perales R., Bentley D. "Cotranscriptionality": the transcription elongation complex as a nexus for nuclear transactions. Mol. Cell 2009, 36(2):178-191.
41. Buratowski S. Progression through the RNA polymerase II CTD cycle. Mol. Cell 2009, 36(4):541-546.
42. Heidemann M., Hintermair C., Voss K., Eick D. Dynamic phosphorylation patterns of RNA polymerase II CTD during transcription. Biochim. Biophys. Acta 2013, 1829(1):55-62.
43. Glover-Cutter K., Kim S., Espinosa J., Bentley D.L. RNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes. Nat. Struct. Mol. Biol. 2008, 15(1):71-78.
44. Aregger M., Cowling V.H. Human cap methyltransferase (RNMT) N-terminal non-catalytic domain mediates recruitment to transcription initiation sites. Biochem. J. 2013, 455(1):67-73.
45. Ho C.K., Shuman S. Distinct roles for CTD Ser-2 and Ser-5 phosphorylation in the recruitment and allosteric activation of mammalian mRNA capping enzyme. Mol. Cell 1999, 3(3):405-411.
46. Ghosh A., Shuman S., Lima C.D. Structural insights to how mammalian capping enzyme reads the CTD code. Mol. Cell 2011, 43(2):299-310.
47. Wen Y., Shatkin A.J. Transcription elongation factor hSPT5 stimulates mRNA capping. Genes Dev. 1999, 13(14):1774-1779.
48. Lidschreiber M., Leike K., Cramer P. Cap completion and C-terminal repeat domain kinase recruitment underlie the initiation-elongation transition of RNA polymerase II. Mol. Cell. Biol. 2013, 33(19):3805-3816.
49. Viladevall L., St Amour C.V., Rosebrock A., Schneider S., Zhang C., Allen J.J., Shokat K.M., Schwer B., Leatherwood J.K., Fisher R.P. TFIIH and P-TEFb coordinate transcription with capping enzyme recruitment at specific genes in fission yeast. Mol. Cell 2009, 33(6):738-751.
50. Mandal S.S., Chu C., Wada T., Handa H., Shatkin A.J., Reinberg D. Functional interactions of RNA-capping enzyme with factors that positively and negatively regulate promoter escape by RNA polymerase II. Proc. Natl. Acad. Sci. U. S. A. 2004, 101(20):7572-7577.
51. Cole M.D., Cowling V.H. Specific regulation of mRNA cap methylation by the c-Myc and E2F1 transcription factors. Oncogene 2009, 28(9):1169-1175.
52. Fernandez-Sanchez M.E., Gonatopoulos-Pournatzis T., Preston G., Lawlor M.A., Cowling V.H. S-adenosyl homocysteine hydrolase is required for Myc-induced mRNA cap methylation, protein synthesis, and cell proliferation. Mol. Cell. Biol. 2009, 29(23):6182-6191.
53. Zeller K.I., Zhao X., Lee C.W., Chiu K.P., Yao F., Yustein J.T., Ooi H.S., Orlov Y.L., Shahab A., Yong H.C., Fu Y., Weng Z., Kuznetsov V.A., Sung W.K., Ruan Y., Dang C.V., Wei C.L. Global mapping of c-Myc binding sites and target gene networks in human B cells. Proc. Natl. Acad. Sci. U. S. A. 2006, 103(47):17834-17839.
54. Fernandez P.C., Frank S.R., Wang L., Schroeder M., Liu S., Greene J., Cocito A., Amati B. Genomic targets of the human c-Myc protein. Genes Dev. 2003, 17(9):1115-1129.
55. Brown S.J., Cole M.D., Erives A.J. Evolution of the holozoan ribosome biogenesis regulon. BMC Genomics 2008, 9:442.
56. McMahon S.B., Van Buskirk H.A., Dugan K.A., Copeland T.D., Cole M.D. The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins. Cell 1998, 94(3):363-374.
57. Chiang P.K., Gordon R.K., Tal J., Zeng G.C., Doctor B.P., Pardhasaradhi K., McCann P.P. S-adenosylmethionine and methylation. FASEB J. 1996, 10(4):471-480.
58. Fustin J.M., Doi M., Yamaguchi Y., Hida H., Nishimura S., Yoshida M., Isagawa T., Morioka M.S., Kakeya H., Manabe I., Okamura H. RNA-methylation-dependent RNA processing controls the speed of the circadian clock. Cell 2013, 155(4):793-806.
59. Jiao X., Xiang S., Oh C., Martin C.E., Tong L., Kiledjian M. Identification of a quality-control mechanism for mRNA 5'-end capping. Nature 2010, 467(7315):608-611.
60. Chang J.H., Jiao X., Chiba K., Oh C., Martin C.E., Kiledjian M., Tong L. Dxo1 is a new type of eukaryotic enzyme with both decapping and 5'-3' exoribonuclease activity. Nat. Struct. Mol. Biol. 2012, 19(10):1011-1017.
61. Jiao X., Chang J.H., Kilic T., Tong L., Kiledjian M. A mammalian pre-mRNA 5' end capping quality control mechanism and an unexpected link of capping to pre-mRNA processing. Mol. Cell 2013, 50(1):104-115.
62. Aregger M., Cowling V.H. E2F1-dependent methyl cap formation requires RNA pol II phosphorylation. Cell Cycle 2012, 11(11):2146-2148.
63. Cowling V.H. Enhanced mRNA cap methylation increases cyclin D1 expression and promotes cell transformation. Oncogene 2009, 29(6):295-302.