메뉴 건너뛰기




Volumn 7, Issue , 2016, Pages

Alterations of the human gut microbiome in multiple sclerosis

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; GLATIRAMER; HLA DRB1 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; METHANE; RNA 16S; STAT5B PROTEIN;

EID: 84976612100     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms12015     Document Type: Article
Times cited : (981)

References (71)
  • 1
    • 84866146940 scopus 로고    scopus 로고
    • Diversity, stability and resilience of the human gut microbiota
    • Lozupone, C. A., Stombaugh, J. I., Gordon, J. I., Jansson, J. K. & Knight, R. Diversity, stability and resilience of the human gut microbiota. Nature 489, 220-230 (2012).
    • (2012) Nature , vol.489 , pp. 220-230
    • Lozupone, C.A.1    Stombaugh, J.I.2    Gordon, J.I.3    Jansson, J.K.4    Knight, R.5
  • 2
    • 84898015600 scopus 로고    scopus 로고
    • The microbiome and regulation of mucosal immunity
    • McDermott, A. J. & Huffnagle, G. B. The microbiome and regulation of mucosal immunity. Immunology 142, 24-31 (2014).
    • (2014) Immunology , vol.142 , pp. 24-31
    • McDermott, A.J.1    Huffnagle, G.B.2
  • 3
    • 84898809123 scopus 로고    scopus 로고
    • The microbiome in inflammatory bowel disease: Current status and the future ahead
    • Kostic, A. D., Xavier, R. J. & Gevers, D. The microbiome in inflammatory bowel disease: current status and the future ahead. Gastroenterology 146, 1489-1499 (2014).
    • (2014) Gastroenterology , vol.146 , pp. 1489-1499
    • Kostic, A.D.1    Xavier, R.J.2    Gevers, D.3
  • 4
    • 84982157002 scopus 로고    scopus 로고
    • Alterations in intestinal microbiota correlate with susceptibility to type 1 diabetes
    • Alkanani, A. K. et al. Alterations in intestinal microbiota correlate with susceptibility to type 1 diabetes. Diabetes 64, 3510-3520 (2015).
    • (2015) Diabetes , vol.64 , pp. 3510-3520
    • Alkanani, A.K.1
  • 5
    • 84887323708 scopus 로고    scopus 로고
    • Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis
    • Scher, J. U. et al. Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis. Elife 2, e01202 (2013).
    • (2013) Elife , vol.2 , pp. e01202
    • Scher, J.U.1
  • 6
    • 81855167104 scopus 로고    scopus 로고
    • Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination
    • Berer, K. et al. Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination. Nature 479, 538-541 (2011).
    • (2011) Nature , vol.479 , pp. 538-541
    • Berer, K.1
  • 7
    • 70350343544 scopus 로고    scopus 로고
    • Induction of intestinal Th17 cells by segmented filamentous bacteria
    • Ivanov, II et al. Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell 139, 485-498 (2009).
    • (2009) Cell , vol.139 , pp. 485-498
    • Ivanov, I.I.1
  • 8
    • 79952748674 scopus 로고    scopus 로고
    • Proinflammatory T-Cell responses to gut microbiota promote experimental autoimmune encephalomyelitis
    • Lee, Y. K., Menezes, J. S., Umesaki, Y. & Mazmanian, S. K. Proinflammatory T-Cell responses to gut microbiota promote experimental autoimmune encephalomyelitis. Proc. Natl. Acad. Sci. USA 108(Suppl 1): 4615-4622 (2011).
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 4615-4622
    • Lee, Y.K.1    Menezes, J.S.2    Umesaki, Y.3    Mazmanian, S.K.4
  • 9
    • 77954738601 scopus 로고    scopus 로고
    • Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota
    • Round, J. L. & Mazmanian, S. K. Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota. Proc. Natl. Acad. Sci. USA 107, 12204-12209 (2010).
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 12204-12209
    • Round, J.L.1    Mazmanian, S.K.2
  • 10
    • 77955913743 scopus 로고    scopus 로고
    • A polysaccharide from the human commensal Bacteroides fragilis protects against CNS demyelinating disease
    • Ochoa-Reparaz, J. et al. A polysaccharide from the human commensal Bacteroides fragilis protects against CNS demyelinating disease. Mucosal Immunol. 3, 487-495 (2010).
    • (2010) Mucosal Immunol , vol.3 , pp. 487-495
    • Ochoa-Reparaz, J.1
  • 11
    • 84947447931 scopus 로고    scopus 로고
    • Dysbiosis in the gut microbiota of patients with multiple sclerosis, with a striking depletion of species belonging to clostridia XIVa and IV clusters
    • Miyake, S. et al. Dysbiosis in the gut microbiota of patients with multiple sclerosis, with a striking depletion of species belonging to clostridia XIVa and IV clusters. PLoS ONE 10, e0137429 (2015).
    • (2015) PLoS ONE , vol.10 , pp. e0137429
    • Miyake, S.1
  • 12
    • 84904048875 scopus 로고    scopus 로고
    • A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis
    • Machiels, K. et al. A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis. Gut 63, 1275-1283 (2014).
    • (2014) Gut , vol.63 , pp. 1275-1283
    • Machiels, K.1
  • 13
    • 84864431745 scopus 로고    scopus 로고
    • Aquaporin 4-specific T cells in neuromyelitis optica exhibit a Th17 bias and recognize Clostridium ABC transporter
    • Varrin-Doyer, M. et al. Aquaporin 4-specific T cells in neuromyelitis optica exhibit a Th17 bias and recognize Clostridium ABC transporter. Ann. Neurol. 72, 53-64 (2012).
    • (2012) Ann. Neurol , vol.72 , pp. 53-64
    • Varrin-Doyer, M.1
  • 14
    • 0029841961 scopus 로고    scopus 로고
    • Campylobacter jejuni infections and anti-GM1 antibodies in Guillain-Barre syndrome
    • Jacobs, B. C. et al. Campylobacter jejuni infections and anti-GM1 antibodies in Guillain-Barre syndrome. Ann. Neurol. 40, 181-187 (1996).
    • (1996) Ann. Neurol , vol.40 , pp. 181-187
    • Jacobs, B.C.1
  • 15
    • 72949107142 scopus 로고    scopus 로고
    • Introducing mothur: Open-source, platform-independent, community-supported software for describing and comparing microbial communities
    • Schloss, P. D. et al. Introducing mothur: open-source, platform-independent, community-supported software for describing and comparing microbial communities. Appl. Environ. Microbiol. 75, 7537-7541 (2009).
    • (2009) Appl. Environ. Microbiol , vol.75 , pp. 7537-7541
    • Schloss, P.D.1
  • 16
    • 77958610660 scopus 로고    scopus 로고
    • Pplacer: Linear time maximum-likelihood and Bayesian phylogenetic placement of sequences onto a fixed reference tree
    • Matsen, F. A., Kodner, R. B. & Armbrust, E. V. pplacer: linear time maximum-likelihood and Bayesian phylogenetic placement of sequences onto a fixed reference tree. BMC Bioinformatics 11, 538 (2010).
    • (2010) BMC Bioinformatics , vol.11 , pp. 538
    • Matsen, F.A.1    Kodner, R.B.2    Armbrust, E.V.3
  • 17
    • 84902660409 scopus 로고    scopus 로고
    • The intestinal archaea Methanosphaera stadtmanae and Methanobrevibacter smithii activate human dendritic cells
    • Bang, C., Weidenbach, K., Gutsmann, T., Heine, H. & Schmitz, R. A. The intestinal archaea Methanosphaera stadtmanae and Methanobrevibacter smithii activate human dendritic cells. PLoS ONE 9, e99411 (2014).
    • (2014) PLoS ONE , vol.9 , pp. e99411
    • Bang, C.1    Weidenbach, K.2    Gutsmann, T.3    Heine, H.4    Schmitz, R.A.5
  • 18
    • 84929630106 scopus 로고    scopus 로고
    • Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis
    • Cao, Y. et al. Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis. Sci. Transl. Med. 7, 287ra274 (2015).
    • (2015) Sci. Transl. Med , vol.7 , pp. 287ra274
    • Cao, Y.1
  • 19
    • 84874099546 scopus 로고    scopus 로고
    • Active relapsing-remitting multiple sclerosis, effector T Cell Res.istance to adaptive T(regs) involves IL-6-mediated signaling
    • Schneider, A. et al. In active relapsing-remitting multiple sclerosis, effector T Cell Res.istance to adaptive T(regs) involves IL-6-mediated signaling. Sci. Transl. Med. 5, 170ra115 (2013).
    • (2013) Sci. Transl. Med , vol.5 , pp. 170ra115
    • Schneider, A.1
  • 20
    • 0036615454 scopus 로고    scopus 로고
    • Inhibitors in the NFkappaB cascade comprise prime candidate genes predisposing to multiple sclerosis, especially in selected combinations
    • Miterski, B. et al. Inhibitors in the NFkappaB cascade comprise prime candidate genes predisposing to multiple sclerosis, especially in selected combinations. Genes Immun. 3, 211-219 (2002).
    • (2002) Genes Immun , vol.3 , pp. 211-219
    • Miterski, B.1
  • 21
    • 77952512771 scopus 로고    scopus 로고
    • Learning from nature: Pregnancy changes the expression of inflammation-related genes in patients with multiple sclerosis
    • Gilli, F. et al. Learning from nature: pregnancy changes the expression of inflammation-related genes in patients with multiple sclerosis. PLoS ONE 5, e8962 (2010).
    • (2010) PLoS ONE , vol.5 , pp. e8962
    • Gilli, F.1
  • 24
    • 80051662149 scopus 로고    scopus 로고
    • Immunogenic properties of archaeal species found in bioaerosols
    • Blais Lecours, P. et al. Immunogenic properties of archaeal species found in bioaerosols. PLoS ONE 6, e23326 (2011).
    • (2011) PLoS ONE , vol.6 , pp. e23326
    • Blais Lecours, P.1
  • 25
    • 0021988294 scopus 로고
    • Methane excretion in man-A study of breath, flatus, and faeces
    • McKay, L. F., Eastwood, M. A. & Brydon, W. G. Methane excretion in man-A study of breath, flatus, and faeces. Gut 26, 69-74 (1985).
    • (1985) Gut , vol.26 , pp. 69-74
    • McKay, L.F.1    Eastwood, M.A.2    Brydon, W.G.3
  • 26
    • 0037286459 scopus 로고    scopus 로고
    • Methane production during lactulose breath test is associated with gastrointestinal disease presentation
    • Pimentel, M. et al. Methane production during lactulose breath test is associated with gastrointestinal disease presentation. Dig. Dis. Sci. 48, 86-92 (2003).
    • (2003) Dig. Dis. Sci , vol.48 , pp. 86-92
    • Pimentel, M.1
  • 27
    • 84905482236 scopus 로고    scopus 로고
    • Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature
    • Haberman, Y. et al. Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature. J. Clin. Invest. 124, 3617-3633 (2014).
    • (2014) J. Clin. Invest , vol.124 , pp. 3617-3633
    • Haberman, Y.1
  • 28
    • 84904241519 scopus 로고    scopus 로고
    • The intestinal microbiome in type 1 diabetes
    • Dunne, J. L. et al. The intestinal microbiome in type 1 diabetes. Clin. Exp. Immunol. 177, 30-37 (2014).
    • (2014) Clin. Exp. Immunol , vol.177 , pp. 30-37
    • Dunne, J.L.1
  • 29
    • 45549092100 scopus 로고    scopus 로고
    • The genetics of multiple sclerosis: SNPs to pathways to pathogenesis
    • Oksenberg, J. R., Baranzini, S. E., Sawcer, S. & Hauser, S. L. The genetics of multiple sclerosis: SNPs to pathways to pathogenesis. Nat. Rev. Genet. 9, 516-526 (2008).
    • (2008) Nat. Rev. Genet , vol.9 , pp. 516-526
    • Oksenberg, J.R.1    Baranzini, S.E.2    Sawcer, S.3    Hauser, S.L.4
  • 30
    • 78049501532 scopus 로고    scopus 로고
    • Real-Time analysis of mucosal flora in patients with inflammatory bowel disease in India
    • Verma, R., Verma, A. K., Ahuja, V. & Paul, J. Real-Time analysis of mucosal flora in patients with inflammatory bowel disease in India. J. Clin. Microbiol. 48, 4279-4282 (2010).
    • (2010) J. Clin. Microbiol , vol.48 , pp. 4279-4282
    • Verma, R.1    Verma, A.K.2    Ahuja, V.3    Paul, J.4
  • 31
    • 50949120461 scopus 로고    scopus 로고
    • Distribution of Archaea in Japanese patients with periodontitis and humoral immune response to the components
    • Yamabe, K. et al. Distribution of Archaea in Japanese patients with periodontitis and humoral immune response to the components. FEMS Microbiol. Lett. 287, 69-75 (2008).
    • (2008) FEMS Microbiol. Lett , vol.287 , pp. 69-75
    • Yamabe, K.1
  • 32
    • 0035253359 scopus 로고    scopus 로고
    • The potent adjuvant activity of archaeosomes correlates to the recruitment and activation of macrophages and dendritic cells in vivo
    • Krishnan, L., Sad, S., Patel, G. B. & Sprott, G. D. The potent adjuvant activity of archaeosomes correlates to the recruitment and activation of macrophages and dendritic cells in vivo. J. Immunol. 166, 1885-1893 (2001).
    • (2001) J. Immunol , vol.166 , pp. 1885-1893
    • Krishnan, L.1    Sad, S.2    Patel, G.B.3    Sprott, G.D.4
  • 33
    • 34447296622 scopus 로고    scopus 로고
    • Genomic and metabolic adaptations of Methanobrevibacter smithii to the human gut
    • Samuel, B. S. et al. Genomic and metabolic adaptations of Methanobrevibacter smithii to the human gut. Proc. Natl. Acad. Sci. USA 104, 10643-10648 (2007).
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 10643-10648
    • Samuel, B.S.1
  • 34
    • 84955183594 scopus 로고    scopus 로고
    • Gut colonization with Methanobrevibacter smithii is associated with childhood weight development
    • Mbakwa, C. A. et al. Gut colonization with Methanobrevibacter smithii is associated with childhood weight development. Obesity (Silver Spring) 23, 2508-2516 (2015).
    • (2015) Obesity (Silver Spring , vol.23 , pp. 2508-2516
    • Mbakwa, C.A.1
  • 35
    • 84959084455 scopus 로고    scopus 로고
    • Gut microbiota composition and relapse risk in pediatric MS: A pilot study
    • Tremlett, H. et al. Gut microbiota composition and relapse risk in pediatric MS: A pilot study. J. Neurol. Sci. 363, 153-157 (2016).
    • (2016) J. Neurol. Sci , vol.363 , pp. 153-157
    • Tremlett, H.1
  • 36
    • 84930361344 scopus 로고    scopus 로고
    • Gut microbiota in multiple sclerosis: Possible influence of immunomodulators
    • Cantarel, B. L. et al. Gut microbiota in multiple sclerosis: possible influence of immunomodulators. J. Invest. Med. 63, 729-734 (2015).
    • (2015) J. Invest. Med , vol.63 , pp. 729-734
    • Cantarel, B.L.1
  • 37
    • 84919932773 scopus 로고    scopus 로고
    • Decreased bacterial diversity characterizes the altered gut microbiota in patients with psoriatic arthritis, resembling dysbiosis in inflammatory bowel disease
    • Scher, J. U. et al. Decreased bacterial diversity characterizes the altered gut microbiota in patients with psoriatic arthritis, resembling dysbiosis in inflammatory bowel disease. Arthritis Rheumatol. 67, 128-139 (2015).
    • (2015) Arthritis Rheumatol , vol.67 , pp. 128-139
    • Scher, J.U.1
  • 38
    • 5444248493 scopus 로고    scopus 로고
    • Akkermansia muciniphila gen. Nov., sp. Nov., a human intestinal mucin-degrading bacterium
    • Derrien, M., Vaughan, E. E., Plugge, C. M. & de Vos, W. M. Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium. Int. J. Syst. Evol. Microbiol. 54, 1469-1476 (2004).
    • (2004) Int. J. Syst. Evol. Microbiol , vol.54 , pp. 1469-1476
    • Derrien, M.1    Vaughan, E.E.2    Plugge, C.M.3    De Vos, W.M.4
  • 39
    • 83655210633 scopus 로고    scopus 로고
    • Modulation of mucosal immune response, tolerance, and proliferation in mice colonized by the mucin-degrader Akkermansia muciniphila
    • Derrien, M. et al. Modulation of mucosal immune response, tolerance, and proliferation in mice colonized by the mucin-degrader Akkermansia muciniphila. Front. Microbiol. 2, 166 (2011).
    • (2011) Front. Microbiol , vol.2 , pp. 166
    • Derrien, M.1
  • 40
    • 84883813272 scopus 로고    scopus 로고
    • Commensal Akkermansia muciniphila exacerbates gut inflammation in Salmonella typhimurium-infected gnotobiotic mice
    • Ganesh, B. P., Klopfleisch, R., Loh, G. & Blaut, M. Commensal Akkermansia muciniphila exacerbates gut inflammation in Salmonella typhimurium-infected gnotobiotic mice. PLoS ONE 8, e74963 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e74963
    • Ganesh, B.P.1    Klopfleisch, R.2    Loh, G.3    Blaut, M.4
  • 41
    • 84890564250 scopus 로고    scopus 로고
    • Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
    • Furusawa, Y. et al. Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells. Nature 504, 446-450 (2013).
    • (2013) Nature , vol.504 , pp. 446-450
    • Furusawa, Y.1
  • 42
    • 84893029775 scopus 로고    scopus 로고
    • Increased proportions of Bifidobacterium and the Lactobacillus group and loss of butyrate-producing bacteria in inflammatory bowel disease
    • Wang, W. et al. Increased proportions of Bifidobacterium and the Lactobacillus group and loss of butyrate-producing bacteria in inflammatory bowel disease. J. Clin. Microbiol. 52, 398-406 (2014).
    • (2014) J. Clin. Microbiol , vol.52 , pp. 398-406
    • Wang, W.1
  • 43
    • 84904741913 scopus 로고    scopus 로고
    • Aberrant gut microbiota composition at the onset of type 1 diabetes in young children
    • de Goffau, M. C. et al. Aberrant gut microbiota composition at the onset of type 1 diabetes in young children. Diabetologia 57, 1569-1577 (2014).
    • (2014) Diabetologia , vol.57 , pp. 1569-1577
    • De Goffau, M.C.1
  • 44
    • 79953748870 scopus 로고    scopus 로고
    • Dysbiosis of the faecal microbiota in patients with Crohns disease and their unaffected relatives
    • Joossens, M. et al. Dysbiosis of the faecal microbiota in patients with Crohns disease and their unaffected relatives. Gut 60, 631-637 (2011).
    • (2011) Gut , vol.60 , pp. 631-637
    • Joossens, M.1
  • 45
    • 80053618114 scopus 로고    scopus 로고
    • Linking long-Term dietary patterns with gut microbial enterotypes
    • Wu, G. D. et al. Linking long-Term dietary patterns with gut microbial enterotypes. Science 334, 105-108 (2011).
    • (2011) Science , vol.334 , pp. 105-108
    • Wu, G.D.1
  • 46
    • 84896092821 scopus 로고    scopus 로고
    • The treatment-naive microbiome in new-onset Crohns disease
    • Gevers, D. et al. The treatment-naive microbiome in new-onset Crohns disease. Cell Host Microbe 15, 382-392 (2014).
    • (2014) Cell Host Microbe , vol.15 , pp. 382-392
    • Gevers, D.1
  • 47
    • 84885156813 scopus 로고    scopus 로고
    • Fecal microbiota and metabolome of children with autism and pervasive developmental disorder not otherwise specified
    • De Angelis, M. et al. Fecal microbiota and metabolome of children with autism and pervasive developmental disorder not otherwise specified. PLoS ONE 8, e76993 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e76993
    • De Angelis, M.1
  • 48
    • 84947718371 scopus 로고    scopus 로고
    • Metagenomic cross-Talk: The regulatory interplay between immunogenomics and the microbiome
    • Levy, M., Thaiss, C. A. & Elinav, E. Metagenomic cross-Talk: The regulatory interplay between immunogenomics and the microbiome. Genome Med. 7, 120 (2015).
    • (2015) Genome Med , vol.7 , pp. 120
    • Levy, M.1    Thaiss, C.A.2    Elinav, E.3
  • 49
    • 84938612863 scopus 로고    scopus 로고
    • Associations between host gene expression, the mucosal microbiome, and clinical outcome in the pelvic pouch of patients with inflammatory bowel disease
    • Morgan, X. C. et al. Associations between host gene expression, the mucosal microbiome, and clinical outcome in the pelvic pouch of patients with inflammatory bowel disease. Genome Biol. 16, 67 (2015).
    • (2015) Genome Biol , vol.16 , pp. 67
    • Morgan, X.C.1
  • 50
    • 1442304886 scopus 로고    scopus 로고
    • Blood transcriptional signatures of multiple sclerosis: Unique gene expression of disease activity
    • Achiron, A., Gurevich, M., Friedman, N., Kaminski, N. & Mandel, M. Blood transcriptional signatures of multiple sclerosis: unique gene expression of disease activity. Ann. Neurol. 55, 410-417 (2004).
    • (2004) Ann. Neurol , vol.55 , pp. 410-417
    • Achiron, A.1    Gurevich, M.2    Friedman, N.3    Kaminski, N.4    Mandel, M.5
  • 51
    • 84927580933 scopus 로고    scopus 로고
    • STAT5 programs a distinct subset of GM-CSF-producing T helper cells that is essential for autoimmune neuroinflammation
    • Sheng, W. et al. STAT5 programs a distinct subset of GM-CSF-producing T helper cells that is essential for autoimmune neuroinflammation. Cell Res. 24, 1387-1402 (2014).
    • (2014) Cell Res , vol.24 , pp. 1387-1402
    • Sheng, W.1
  • 52
    • 84871627299 scopus 로고    scopus 로고
    • Methanobrevibacter smithii is the predominant methanogen in patients with constipation-predominant IBS and methane on breath
    • Kim, G. et al. Methanobrevibacter smithii is the predominant methanogen in patients with constipation-predominant IBS and methane on breath. Dig. Dis. Sci. 57, 3213-3218 (2012).
    • (2012) Dig. Dis. Sci , vol.57 , pp. 3213-3218
    • Kim, G.1
  • 53
    • 84877679896 scopus 로고    scopus 로고
    • May diet and dietary supplements improve the wellness of multiple sclerosis patients? A molecular approach
    • Riccio, P., Rossano, R. & Liuzzi, G. M. May diet and dietary supplements improve the wellness of multiple sclerosis patients? A molecular approach. Autoimmune Dis. 2010, 249842 (2011).
    • (2010) Autoimmune Dis , vol.2011 , pp. 249842
    • Riccio, P.1    Rossano, R.2    Liuzzi, G.M.3
  • 54
    • 78650616947 scopus 로고    scopus 로고
    • Toward defining the autoimmune microbiome for type 1 diabetes
    • Giongo, A. et al. Toward defining the autoimmune microbiome for type 1 diabetes. ISME J. 5, 82-91 (2011).
    • (2011) ISME J , vol.5 , pp. 82-91
    • Giongo, A.1
  • 55
    • 84862286169 scopus 로고    scopus 로고
    • A framework for human microbiome research
    • Human Microbiome Project C
    • Human Microbiome Project, C. A framework for human microbiome research. Nature 486, 215-221 (2012).
    • (2012) Nature , vol.486 , pp. 215-221
  • 56
    • 84862276328 scopus 로고    scopus 로고
    • Function and diversity of the healthy human microbiome
    • Human Microbiome Project C. Structure
    • Human Microbiome Project, C. Structure, function and diversity of the healthy human microbiome. Nature 486, 207-214 (2012).
    • (2012) Nature , vol.486 , pp. 207-214
  • 57
    • 84863981120 scopus 로고    scopus 로고
    • Ultra-high-Throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms
    • Caporaso, J. G. et al. Ultra-high-Throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms. ISME J. 6, 1621-1624 (2012).
    • (2012) ISME J , vol.6 , pp. 1621-1624
    • Caporaso, J.G.1
  • 58
    • 84940644968 scopus 로고
    • A mathematical theory of communication
    • Shannon, C. E. W. W. A Mathematical Theory of Communication. Bell Syst. Tech. J. 27, 379-423 (1948).
    • (1948) Bell Syst. Tech. J , vol.27 , pp. 379-423
    • Shannon, C.E.W.W.1
  • 59
    • 84950618101 scopus 로고
    • Constructing confidence sets using rank statistics
    • D. F., Bauer Constructing confidence sets using rank statistics. J. Am. Stat. Assoc. 67, 687-690 (1972).
    • (1972) J. Am. Stat. Assoc , vol.67 , pp. 687-690
    • Bauer, D.F.1
  • 60
    • 29144464937 scopus 로고    scopus 로고
    • UniFrac: A new phylogenetic method for comparing microbial communities
    • Lozupone, C. & Knight, R. UniFrac: A new phylogenetic method for comparing microbial communities. Appl. Environ. Microbiol. 71, 8228-8235 (2005).
    • (2005) Appl. Environ. Microbiol , vol.71 , pp. 8228-8235
    • Lozupone, C.1    Knight, R.2
  • 61
    • 0026681074 scopus 로고
    • Analysis of molecular variance inferred from metric distances among DNA haplotypes: Application to human mitochondrial DNA restriction data
    • Excoffier, L., Smouse, P. E. & Quattro, J. M. Analysis of molecular variance inferred from metric distances among DNA haplotypes: Application to human mitochondrial DNA restriction data. Genetics 131, 479-491 (1992).
    • (1992) Genetics , vol.131 , pp. 479-491
    • Excoffier, L.1    Smouse, P.E.2    Quattro, J.M.3
  • 62
    • 84924629414 scopus 로고    scopus 로고
    • Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
    • Love, M. I., Huber, W. & Anders, S. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol. 15, 550 (2014).
    • (2014) Genome Biol , vol.15 , pp. 550
    • Love, M.I.1    Huber, W.2    Anders, S.3
  • 63
    • 84901363655 scopus 로고    scopus 로고
    • Waste not, want not: Why rarefying microbiome data is inadmissible
    • McMurdie, P.J. & Holmes, S. Waste not, want not: why rarefying microbiome data is inadmissible. PLoS Comput. Biol. 10 (2014).
    • (2014) PLoS Comput. Biol , vol.10
    • McMurdie, P.J.1    Holmes, S.2
  • 64
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini, Y. & Hochberg, Y. Controlling the false discovery rate: A practical and powerful approach to multiple testing. J.R. Stat. Soc. B 57, 289-300 (1995).
    • (1995) J.R. Stat. Soc B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 65
    • 84891787231 scopus 로고    scopus 로고
    • Ribosomal Database Project: Data and tools for high throughput rRNA analysis
    • Cole, J. R. et al. Ribosomal Database Project: data and tools for high throughput rRNA analysis. Nucleic Acids Res. 42, D633-D642 (2014).
    • (2014) Nucleic Acids Res , vol.42 , pp. D633-D642
    • Cole, J.R.1
  • 66
    • 13244255415 scopus 로고    scopus 로고
    • MUSCLE: A multiple sequence alignment method with reduced time and space complexity
    • Edgar, R. C. MUSCLE: A multiple sequence alignment method with reduced time and space complexity. BMC Bioinformatics 5, 113 (2004).
    • (2004) BMC Bioinformatics , vol.5 , pp. 113
    • Edgar, R.C.1
  • 67
    • 67649327176 scopus 로고    scopus 로고
    • FastTree: Computing large minimum evolution trees with profiles instead of a distance matrix
    • Price, M. N., Dehal, P. S. & Arkin, A. P. FastTree: computing large minimum evolution trees with profiles instead of a distance matrix. Mol. Biol. Evol. 26, 1641-1650 (2009).
    • (2009) Mol. Biol. Evol , vol.26 , pp. 1641-1650
    • Price, M.N.1    Dehal, P.S.2    Arkin, A.P.3
  • 69
    • 84952011329 scopus 로고    scopus 로고
    • Identification of a novel mechanism of action of fingolimod (FTY720) on human effector T cell function through TCF-1 upregulation
    • Mazzola, M. A. et al. Identification of a novel mechanism of action of fingolimod (FTY720) on human effector T cell function through TCF-1 upregulation. J. Neuroinflamm. 12, 245 (2015).
    • (2015) J. Neuroinflamm , vol.12 , pp. 245
    • Mazzola, M.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.