Pro-inflammatory IL-1beta and/or TNF-alpha up-regulate matrix metalloproteases-1 and -3 mRNA in chondrocyte subpopulations potentially pathogenic in osteoarthritis: in situ hybridization studies on a single cell level

International Journal of Rheumatic Diseases

Volumn 19, Issue 6, 2016, Pages 557-566

  Kunisch, Elke ^a   Kinne, Raimund W ^a   Alsalameh, Rayya J ^b   Alsalameh, Saifeddin ^c  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

chondrocyte subpopulations; IL 1beta; in situ hybridization; MMP; TGF beta1; TIMP; TNF alpha

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 2; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE; MESSENGER RNA; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; CARTILAGE CELL; CELL CULTURE; CELL SUBPOPULATION; CONTROLLED STUDY; DOWN REGULATION; FEMALE; HUMAN; HUMAN CELL; IN SITU HYBRIDIZATION; MALE; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

EID: 84976603138     PISSN: 17561841     EISSN: 1756185X     Source Type: Journal    
DOI: 10.1111/1756-185X.12431     Document Type: Article

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