-
1
-
-
84949801835
-
The Concise Guide to PHARMACOLOGY 2015/16: G protein-coupled receptors
-
Alexander SPH, Davenport AP, Kelly E, Marrion N, Peters JA, Benson HE et al. (2015). The Concise Guide to PHARMACOLOGY 2015/16: G protein-coupled receptors. Br J Pharmacol 172: 5744–5869.
-
(2015)
Br J Pharmacol
, vol.172
, pp. 5744-5869
-
-
Alexander, S.P.H.1
Davenport, A.P.2
Kelly, E.3
Marrion, N.4
Peters, J.A.5
Benson, H.E.6
-
3
-
-
84943302818
-
Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat
-
bav063
-
Babbitt PC, Bagos PG, Bairoch A, Bateman A, Chatonnet A, Chen MJ et al. (2015). Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat. Database 2015.bav063
-
(2015)
Database
, vol.2015
-
-
Babbitt, P.C.1
Bagos, P.G.2
Bairoch, A.3
Bateman, A.4
Chatonnet, A.5
Chen, M.J.6
-
4
-
-
77957055780
-
Integrated methods for the construction of three-dimensional models and computational probing of structure–function relations in G protein-coupled receptors
-
Ballesteros JA, Weinstein H (1995). Integrated methods for the construction of three-dimensional models and computational probing of structure–function relations in G protein-coupled receptors. Methods Neurosci 25: 366–428.
-
(1995)
Methods Neurosci
, vol.25
, pp. 366-428
-
-
Ballesteros, J.A.1
Weinstein, H.2
-
5
-
-
0008600208
-
TinyGRAP database: a bioinformatics tool to mine G-protein-coupled receptor mutant data
-
Beukers MW, Kristiansen K, Ijzerman AP, Edvardsen O (1999). TinyGRAP database: a bioinformatics tool to mine G-protein-coupled receptor mutant data. Trends Pharmacol Sci 20: 475–477.
-
(1999)
Trends Pharmacol Sci
, vol.20
, pp. 475-477
-
-
Beukers, M.W.1
Kristiansen, K.2
Ijzerman, A.P.3
Edvardsen, O.4
-
6
-
-
79960176452
-
Progress in structure based drug design for G protein-coupled receptors
-
Congreve M, Langmead CJ, Mason JS, Marshall FH (2011). Progress in structure based drug design for G protein-coupled receptors. J Med Chem 54: 4283–4311.
-
(2011)
J Med Chem
, vol.54
, pp. 4283-4311
-
-
Congreve, M.1
Langmead, C.J.2
Mason, J.S.3
Marshall, F.H.4
-
7
-
-
33845868822
-
PHASE: a new engine for pharmacophore perception, 3D QSAR model development, and 3D database screening: 1. Methodology and preliminary results
-
Dixon S, Smondyrev A, Knoll E, Rao S, Shaw D, Friesner R (2006). PHASE: a new engine for pharmacophore perception, 3D QSAR model development, and 3D database screening: 1. Methodology and preliminary results. J Comput Aided Mol Des 20: 647–671.
-
(2006)
J Comput Aided Mol Des
, vol.20
, pp. 647-671
-
-
Dixon, S.1
Smondyrev, A.2
Knoll, E.3
Rao, S.4
Shaw, D.5
Friesner, R.6
-
8
-
-
0000122573
-
PHYLIP – Phylogeny Inference Package (Version 3.2)
-
Felsenstein J (1989). PHYLIP – Phylogeny Inference Package (Version 3.2). Cladistics 5: 164–166.
-
(1989)
Cladistics
, vol.5
, pp. 164-166
-
-
Felsenstein, J.1
-
9
-
-
84927740634
-
A new crystal structure fragment-based pharmacophore method for G protein-coupled receptors
-
Fidom K, Isberg V, Hauser AS, Mordalski S, Lehto T, Bojarski AJ et al. (2015). A new crystal structure fragment-based pharmacophore method for G protein-coupled receptors. Methods 71: 104–112.
-
(2015)
Methods
, vol.71
, pp. 104-112
-
-
Fidom, K.1
Isberg, V.2
Hauser, A.S.3
Mordalski, S.4
Lehto, T.5
Bojarski, A.J.6
-
10
-
-
0038024615
-
The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints
-
Fredriksson R, Lagerström MC, Lundin L-G, Schiöth HB (2003). The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. Mol Pharmacol 63: 1256–1272.
-
(2003)
Mol Pharmacol
, vol.63
, pp. 1256-1272
-
-
Fredriksson, R.1
Lagerström, M.C.2
Lundin, L.-G.3
Schiöth, H.B.4
-
11
-
-
67650753759
-
Definition of the G protein-coupled receptor transmembrane bundle binding pocket and calculation of receptor similarities for drug design
-
Gloriam DE, Foord SM, Blaney FE, Garland SL (2009). Definition of the G protein-coupled receptor transmembrane bundle binding pocket and calculation of receptor similarities for drug design. J Med Chem 52: 4429–4442.
-
(2009)
J Med Chem
, vol.52
, pp. 4429-4442
-
-
Gloriam, D.E.1
Foord, S.M.2
Blaney, F.E.3
Garland, S.L.4
-
12
-
-
0037252680
-
GPCRDB information system for G protein-coupled receptors
-
Horn F, Bettler E, Oliveira L, Campagne F, Cohen FE, Vriend G (2003). GPCRDB information system for G protein-coupled receptors. Nucleic Acids Res 31: 294–297.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 294-297
-
-
Horn, F.1
Bettler, E.2
Oliveira, L.3
Campagne, F.4
Cohen, F.E.5
Vriend, G.6
-
13
-
-
0031803634
-
GPCRDB: an information system for G protein-coupled receptors
-
Horn F, Weare J, Beukers MW, Horsch S, Bairoch A, Chen W et al. (1998). GPCRDB: an information system for G protein-coupled receptors. Nucleic Acids Res 26: 275–279.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 275-279
-
-
Horn, F.1
Weare, J.2
Beukers, M.W.3
Horsch, S.4
Bairoch, A.5
Chen, W.6
-
14
-
-
84939795137
-
Structural insights into [micro]-opioid receptor activation
-
Huang W, Manglik A, Venkatakrishnan AJ, Laeremans T, Feinberg EN, Sanborn AL et al. (2015). Structural insights into [micro]-opioid receptor activation. Nature 524: 315–321.
-
(2015)
Nature
, vol.524
, pp. 315-321
-
-
Huang, W.1
Manglik, A.2
Venkatakrishnan, A.J.3
Laeremans, T.4
Feinberg, E.N.5
Sanborn, A.L.6
-
15
-
-
84891760740
-
GPCRDB: an information system for G protein-coupled receptors
-
Isberg V, Vroling B, van der Kant R, Li K, Vriend G, Gloriam D (2014). GPCRDB: an information system for G protein-coupled receptors. Nucleic Acids Res 42: D422–D425.
-
(2014)
Nucleic Acids Res
, vol.42
, pp. D422-D425
-
-
Isberg, V.1
Vroling, B.2
van der Kant, R.3
Li, K.4
Vriend, G.5
Gloriam, D.6
-
16
-
-
84976904319
-
GPCRdb: an information system for G protein-coupled receptors
-
Isberg V, Mordalski S, Munk C, Rataj K, Harpsoe K, Hauser AS et al. (2016). GPCRdb: an information system for G protein-coupled receptors. Nucleic Acids Res 44: D356–D364.
-
(2016)
Nucleic Acids Res
, vol.44
, pp. D356-D364
-
-
Isberg, V.1
Mordalski, S.2
Munk, C.3
Rataj, K.4
Harpsoe, K.5
Hauser, A.S.6
-
17
-
-
84920166693
-
Generic GPCR residue numbers – aligning topology maps while minding the gaps
-
Isberg V, de Graaf C, Bortolato A, Cherezov V, Katritch V, Marshall FH et al. (2015). Generic GPCR residue numbers – aligning topology maps while minding the gaps. Trends Pharmacol Sci 36: 22–31.
-
(2015)
Trends Pharmacol Sci
, vol.36
, pp. 22-31
-
-
Isberg, V.1
de Graaf, C.2
Bortolato, A.3
Cherezov, V.4
Katritch, V.5
Marshall, F.H.6
-
18
-
-
48449090786
-
NCBI BLAST: a better web interface
-
Johnson M, Zaretskaya I, Raytselis Y, Merezhuk Y, McGinnis S, Madden TL (2008). NCBI BLAST: a better web interface. Nucleic Acids Res 36: W5–W9.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. W5-W9
-
-
Johnson, M.1
Zaretskaya, I.2
Raytselis, Y.3
Merezhuk, Y.4
McGinnis, S.5
Madden, T.L.6
-
19
-
-
84938359988
-
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
-
Kang Y, Zhou XE, Gao X, He Y, Liu W, Ishchenko A et al. (2015). Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser. Nature 523: 561–567.
-
(2015)
Nature
, vol.523
, pp. 561-567
-
-
Kang, Y.1
Zhou, X.E.2
Gao, X.3
He, Y.4
Liu, W.5
Ishchenko, A.6
-
21
-
-
0028338534
-
GCRDb: a G-protein-coupled receptor database
-
Kolakowski LF Jr (1994). GCRDb: a G-protein-coupled receptor database. Receptors Channels 2: 1–7.
-
(1994)
Receptors Channels
, vol.2
, pp. 1-7
-
-
Kolakowski, L.F.1
-
22
-
-
80051521545
-
Status of GPCR modeling and docking as reflected by community-wide GPCR Dock 2010 assessment
-
Kufareva I, Rueda M, Katritch V, Stevens RC, Abagyan R (2011). Status of GPCR modeling and docking as reflected by community-wide GPCR Dock 2010 assessment. Structure 19: 1108–1126.
-
(2011)
Structure
, vol.19
, pp. 1108-1126
-
-
Kufareva, I.1
Rueda, M.2
Katritch, V.3
Stevens, R.C.4
Abagyan, R.5
-
23
-
-
84905732337
-
Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment: meeting new challenges
-
Kufareva I, Katritch V, Participants of GD, Stevens RC, Abagyan R (2014). Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment: meeting new challenges. Structure 22: 1120–1139.
-
(2014)
Structure
, vol.22
, pp. 1120-1139
-
-
Kufareva, I.1
Katritch, V.2
Stevens, R.C.3
Abagyan, R.4
-
24
-
-
42149181885
-
Structural diversity of G protein-coupled receptors and significance for drug discovery
-
Lagerstrom MC, Schioth HB (2008). Structural diversity of G protein-coupled receptors and significance for drug discovery. Nat Rev Drug Discov 7: 339–357.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 339-357
-
-
Lagerstrom, M.C.1
Schioth, H.B.2
-
25
-
-
84874522517
-
Towards improved quality of GPCR models by usage of multiple templates and profile–profile comparison
-
Latek D, Pasznik P, Carlomagno T, Filipek S (2013). Towards improved quality of GPCR models by usage of multiple templates and profile–profile comparison. PLoS One 8: e56742.
-
(2013)
PLoS One
, vol.8
-
-
Latek, D.1
Pasznik, P.2
Carlomagno, T.3
Filipek, S.4
-
26
-
-
77249106566
-
Three-dimensional pharmacophore methods in drug discovery
-
Leach AR, Gillet VJ, Lewis RA, Taylor R (2009). Three-dimensional pharmacophore methods in drug discovery. J Med Chem 53: 539–558.
-
(2009)
J Med Chem
, vol.53
, pp. 539-558
-
-
Leach, A.R.1
Gillet, V.J.2
Lewis, R.A.3
Taylor, R.4
-
27
-
-
67349088738
-
Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008. Nature reviews
-
Michino M, Abola E, Brooks CL 3rd, Dixon JS, Moult J, Stevens RC (2009). Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008. Nature reviews. Drug Discov 8: 455–463.
-
(2009)
Drug Discov
, vol.8
, pp. 455-463
-
-
Michino, M.1
Abola, E.2
Brooks, C.L.3
Dixon, J.S.4
Moult, J.5
Stevens, R.C.6
-
28
-
-
1842464122
-
Genes and ligands for odorant, vomeronasal and taste receptors
-
Mombaerts P (2004). Genes and ligands for odorant, vomeronasal and taste receptors. Nat Rev Neurosci 5: 263–278.
-
(2004)
Nat Rev Neurosci
, vol.5
, pp. 263-278
-
-
Mombaerts, P.1
-
30
-
-
80052158550
-
Independent HHsearch, Needleman–Wunsch-based, and motif analyses reveal the overall hierarchy for most of the G protein-coupled receptor families
-
Nordstrom KJ, Sallman Almen M, Edstam MM, Fredriksson R, Schioth HB (2011). Independent HHsearch, Needleman–Wunsch-based, and motif analyses reveal the overall hierarchy for most of the G protein-coupled receptor families. Mol Biol Evol 28: 2471–2480.
-
(2011)
Mol Biol Evol
, vol.28
, pp. 2471-2480
-
-
Nordstrom, K.J.1
Sallman Almen, M.2
Edstam, M.M.3
Fredriksson, R.4
Schioth, H.B.5
-
31
-
-
84976573757
-
-
Science-Business eXchange
-
Parmley S (2014). GPCRs' grand plans. Science-Business eXchange 7.
-
(2014)
GPCRs' grand plans
, vol.7
-
-
Parmley, S.1
-
32
-
-
84891751622
-
The druggable genome: evaluation of drug targets in clinical trials suggests major shifts in molecular class and indication
-
Rask-Andersen M, Masuram S, Schioth HB (2014). The druggable genome: evaluation of drug targets in clinical trials suggests major shifts in molecular class and indication. Annu Rev Pharmacol Toxicol 54: 9–26.
-
(2014)
Annu Rev Pharmacol Toxicol
, vol.54
, pp. 9-26
-
-
Rask-Andersen, M.1
Masuram, S.2
Schioth, H.B.3
-
33
-
-
80051658642
-
Crystal structure of the beta2 adrenergic receptor-Gs protein complex
-
Rasmussen SG, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS et al. (2011). Crystal structure of the beta2 adrenergic receptor-Gs protein complex. Nature 477: 549–555.
-
(2011)
Nature
, vol.477
, pp. 549-555
-
-
Rasmussen, S.G.1
DeVree, B.T.2
Zou, Y.3
Kruse, A.C.4
Chung, K.Y.5
Kobilka, T.S.6
-
34
-
-
84861027751
-
Molecular modelling of G protein-coupled receptors through the web
-
Rodríguez D, Bello X, Gutiérrez-de-Terán H (2012). Molecular modelling of G protein-coupled receptors through the web. Mol Inform 31: 334–341.
-
(2012)
Mol Inform
, vol.31
, pp. 334-341
-
-
Rodríguez, D.1
Bello, X.2
Gutiérrez-de-Terán, H.3
-
35
-
-
84946045336
-
The RCSB protein data bank: views of structural biology for basic and applied research and education
-
Rose PW, Prlic A, Bi C, Bluhm WF, Christie CH, Dutta S et al. (2015). The RCSB protein data bank: views of structural biology for basic and applied research and education. Nucleic Acids Res 43: D345–D356.
-
(2015)
Nucleic Acids Res
, vol.43
, pp. D345-D356
-
-
Rose, P.W.1
Prlic, A.2
Bi, C.3
Bluhm, W.F.4
Christie, C.H.5
Dutta, S.6
-
36
-
-
80053615320
-
The significance of G protein-coupled receptor crystallography for drug discovery
-
Salon JA, Lodowski DT, Palczewski K (2011). The significance of G protein-coupled receptor crystallography for drug discovery. Pharmacol Rev 63: 901–937.
-
(2011)
Pharmacol Rev
, vol.63
, pp. 901-937
-
-
Salon, J.A.1
Lodowski, D.T.2
Palczewski, K.3
-
37
-
-
84883644943
-
GOMoDo: a GPCRs online modeling and docking webserver
-
Sandal M, Duy TP, Cona M, Zung H, Carloni P, Musiani F et al. (2013). GOMoDo: a GPCRs online modeling and docking webserver. PLoS One 8: e74092.
-
(2013)
PLoS One
, vol.8
-
-
Sandal, M.1
Duy, T.P.2
Cona, M.3
Zung, H.4
Carloni, P.5
Musiani, F.6
-
38
-
-
52949102889
-
Crystal structure of opsin in its G-protein-interacting conformation
-
Scheerer P, Park JH, Hildebrand PW, Kim YJ, Krauss N, Choe H-W et al. (2008). Crystal structure of opsin in its G-protein-interacting conformation. Nature 455: 497–502.
-
(2008)
Nature
, vol.455
, pp. 497-502
-
-
Scheerer, P.1
Park, J.H.2
Hildebrand, P.W.3
Kim, Y.J.4
Krauss, N.5
Choe, H.-W.6
-
39
-
-
84976865494
-
The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands
-
Southan C, Sharman JL, Benson HE, Faccenda E, Pawson AJ, Alexander SP et al. (2016). The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. Nucleic Acids Res 44: D1054–D1068.
-
(2016)
Nucleic Acids Res
, vol.44
, pp. D1054-D1068
-
-
Southan, C.1
Sharman, J.L.2
Benson, H.E.3
Faccenda, E.4
Pawson, A.J.5
Alexander, S.P.6
-
40
-
-
84898901491
-
Unifying family A GPCR theories of activation
-
Tehan BG, Bortolato A, Blaney FE, Weir MP, Mason JS (2014). Unifying family A GPCR theories of activation. Pharmacol Ther 143: 51–60.
-
(2014)
Pharmacol Ther
, vol.143
, pp. 51-60
-
-
Tehan, B.G.1
Bortolato, A.2
Blaney, F.E.3
Weir, M.P.4
Mason, J.S.5
-
41
-
-
84873685831
-
Molecular signatures of G-protein-coupled receptors
-
Venkatakrishnan AJ, Deupi X, Lebon G, Tate CG, Schertler GF, Babu MM (2013). Molecular signatures of G-protein-coupled receptors. Nature 494: 185–194.
-
(2013)
Nature
, vol.494
, pp. 185-194
-
-
Venkatakrishnan, A.J.1
Deupi, X.2
Lebon, G.3
Tate, C.G.4
Schertler, G.F.5
Babu, M.M.6
-
42
-
-
0035895505
-
The sequence of the human genome
-
Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG et al. (2001). The sequence of the human genome. Science 291: 1304–1351.
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
Li, P.W.4
Mural, R.J.5
Sutton, G.G.6
-
43
-
-
78651297517
-
GPCRDB: information system for G protein-coupled receptors
-
Vroling B, Sanders M, Baakman C, Borrmann A, Verhoeven S, Klomp J et al. (2011). GPCRDB: information system for G protein-coupled receptors. Nucleic Acids Res 39: 309–319.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 309-319
-
-
Vroling, B.1
Sanders, M.2
Baakman, C.3
Borrmann, A.4
Verhoeven, S.5
Klomp, J.6
-
44
-
-
79956201434
-
GPCR-SSFE: a comprehensive database of G-protein-coupled receptor template predictions and homology models
-
Worth CL, Kreuchwig A, Kleinau G, Krause G (2011). GPCR-SSFE: a comprehensive database of G-protein-coupled receptor template predictions and homology models. BMC Bioinformatics 12: 185.
-
(2011)
BMC Bioinformatics
, vol.12
, pp. 185
-
-
Worth, C.L.1
Kreuchwig, A.2
Kleinau, G.3
Krause, G.4
|