A role for nuclear actin in HDAC 1 and 2 regulation

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Serebryannyy, Leonid A ^a   Cruz, Christina M ^a   De Lanerolle, Primal ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2;

ACTIN FILAMENT; ANIMAL; CELL NUCLEUS; CHLOROCEBUS AETHIOPS; CV-1 CELL LINE; FLUORESCENCE MICROSCOPY; HELA CELL LINE; HUMAN; IMMUNOPRECIPITATION; METABOLISM;

ACTIN CYTOSKELETON; ACTINS; ANIMALS; CELL NUCLEUS; CERCOPITHECUS AETHIOPS; COS CELLS; HELA CELLS; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HUMANS; IMMUNOPRECIPITATION; MICROSCOPY, FLUORESCENCE;

EID: 84976371088     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep28460     Document Type: Article

References (53)

1. Dokmanovic, M., Clarke, C. & Marks, P. A. Histone deacetylase inhibitors: overview and perspectives. Mol Cancer Res 5, 981-9 (2007).
2. Yang, X. J. & Seto, E. HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention. Oncogene 26, 5310-8 (2007).
3. Hayakawa, T. & Nakayama, J. Physiological roles of class I HDAC complex and histone demethylase. J Biomed Biotechnol 2011, 129383 (2011).
4. de Ruijter, A. J., van Gennip, A. H., Caron, H. N., Kemp, S. & van Kuilenburg, A. B. Histone deacetylases (HDACs): characterization of the classical HDAC family. Biochem J 370, 737-49 (2003).
5. Delcuve, G. P., Khan, D. H. & Davie, J. R. Roles of histone deacetylases in epigenetic regulation: emerging paradigms from studies with inhibitors. Clin Epigenetics 4, 5 (2012).
6. Wang, Z. et al. Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes. Cell 138, 1019-31 (2009).
7. New, M., Olzscha, H. & La Thangue, N. B. HDAC inhibitor-based therapies: can we interpret the code? Mol Oncol 6, 637-56 (2012).
8. Joshi, P. et al. The functional interactome landscape of the human histone deacetylase family. Mol Syst Biol 9, 672 (2013).
9. Huang, W. et al. Coronin 2A mediates actin-dependent de-repression of inflammatory response genes. Nature 470, 414-8 (2011).
10. Andrin, C. & Hendzel, M. J. F-actin-dependent insolubility of chromatin-modifying components. J Biol Chem 279, 25017-23 (2004).
11. Waltregny, D. et al. Histone deacetylase HDAC8 associates with smooth muscle alpha-actin and is essential for smooth muscle cell contractility. FASEB J 19, 966-8 (2005).
12. Pollard, T. D. & Cooper, J. A. Actin, a central player in cell shape and movement. Science 326, 1208-12 (2009).
13. de Lanerolle, P. & Serebryannyy, L. Nuclear actin and myosins: life without filaments. Nat Cell Biol 13, 1282-8 (2011).
14. Kapoor, P., Chen, M., Winkler, D. D., Luger, K. & Shen, X. Evidence for monomeric actin function in INO80 chromatin remodeling. Nat Struct Mol Biol 20, 426-32 (2013).
15. Tosi, A. et al. Structure and subunit topology of the INO80 chromatin remodeler and its nucleosome complex. Cell 154, 1207-19 (2013).
16. Obrdlik, A. et al. The histone acetyltransferase PCAF associates with actin and hnRNP U for RNA polymerase II transcription. Mol Cell Biol 28, 6342-57 (2008).
17. Zhao, K. et al. Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling. Cell 95, 625-36 (1998).
18. Szerlong, H. et al. The HSA domain binds nuclear actin-related proteins to regulate chromatin-remodeling ATPases. Nat Struct Mol Biol 15, 469-76 (2008).
19. Qi, T. et al. G-actin Participates in RNA Polymerase II-dependent Transcription Elongation by Recruiting Positive Transcription Elongation Factor b (P-TEFb). J Biol Chem 286, 15171-81 (2011).
20. Fuchs, M. et al. The p400 complex is an essential E1A transformation target. Cell 106, 297-307 (2001).
21. Ikura, T. et al. Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis. Cell 102, 463-73 (2000).
22. Galarneau, L. et al. Multiple links between the NuA4 histone acetyltransferase complex and epigenetic control of transcription. Mol Cell 5, 927-37 (2000).
23. Kapoor, P. & Shen, X. Mechanisms of nuclear actin in chromatin-remodeling complexes. Trends Cell Biol 24, 238-46 (2014).
24. Posern, G., Sotiropoulos, A. & Treisman, R. Mutant actins demonstrate a role for unpolymerized actin in control of transcription by serum response factor. Mol Biol Cell 13, 4167-78 (2002).
25. Murao, S., Gemmell, M. A., Callaham, M. F., Anderson, N. L. & Huberman, E. Control of macrophage cell differentiation in human promyelocytic HL-60 leukemia cells by 1, 25-dihydroxyvitamin D3 and phorbol-12-myristate-13-acetate. Cancer Res 43, 4989-96 (1983).
26. Wada, T. et al. Expression levels of histone deacetylases determine the cell fate of hematopoietic progenitors. J Biol Chem 284, 30673-83 (2009).
27. Yamagoe, S. et al. Interaction of histone acetylases and deacetylases in vivo. Mol Cell Biol 23, 1025-33 (2003).
28. Xu, Y. Z., Thuraisingam, T., Morais, D. A., Rola-Pleszczynski, M. & Radzioch, D. Nuclear translocation of beta-actin is involved in transcriptional regulation during macrophage differentiation of HL-60 cells. Mol Biol Cell 21, 811-20 (2010).
29. Vaidya, A. S. et al. Design, synthesis, modeling, biological evaluation and photoaffinity labeling studies of novel series of photoreactive benzamide probes for histone deacetylase 2. Bioorg Med Chem Lett 22, 5025-30 (2012).
30. Abe, A., Saeki, K., Yasunaga, T. & Wakabayashi, T. Acetylation at the N-terminus of actin strengthens weak interaction between actin and myosin. Biochem Biophys Res Commun 268, 14-9 (2000).
31. Choudhary, C. et al. Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science 325, 834-40 (2009).
32. Wulfkuhle, J. D. et al. Domain analysis of supervillin, an F-actin bundling plasma membrane protein with functional nuclear localization signals. J Cell Sci 112 (Pt 13), 2125-36 (1999).
33. Szabo, G. Jr., Damjanovich, S., Sumegi, J. & Klein, G. Overall changes in chromatin sensitivity to DNase I during differentiation. Exp Cell Res 169, 158-68 (1987).
34. Weintraub, H. & Groudine, M. Chromosomal subunits in active genes have an altered conformation. Science 193, 848-56 (1976).
35. Miller, K. M. et al. Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous endjoining. Nat Struct Mol Biol 17, 1144-51 (2010).
36. Giannini, G., Cabri, W., Fattorusso, C. & Rodriquez, M. Histone deacetylase inhibitors in the treatment of cancer: overview and perspectives. Future Med Chem 4, 1439-60 (2012).
37. Hamada, F. & Bienz, M. The APC tumor suppressor binds to C-terminal binding protein to divert nuclear beta-catenin from TCF. Dev Cell 7, 677-85 (2004).
38. Moseley, J. B. et al. Regulated binding of adenomatous polyposis coli protein to actin. J Biol Chem 282, 12661-8 (2007).
39. Lee, M., Ji, H., Furuta, Y., Park, J. I. & McCrea, P. D. p120-catenin regulates REST and CoREST, and modulates mouse embryonic stem cell differentiation. J Cell Sci 127, 4037-51 (2014).
40. Yap, K. L. et al. NAC1 is an actin-binding protein that is essential for effective cytokinesis in cancer cells. Cancer Res 72, 4085-96 (2012).
41. Korutla, L., Degnan, R., Wang, P. & Mackler, S. A. NAC1, a cocaine-regulated POZ/BTB protein interacts with CoREST. J Neurochem 101, 611-8 (2007).
42. Ito, A. et al. The subcellular localization and activity of cortactin is regulated by acetylation and interaction with Keap1. Sci Signal 8, ra120 (2015).
43. Song, E. H. et al. Acetylation of the RhoA GEF Net1A controls its subcellular localization and activity. J Cell Sci 128, 913-22 (2015).
44. di Bari, M. G. et al. c-Abl acetylation by histone acetyltransferases regulates its nuclear-cytoplasmic localization. EMBO Rep 7, 727-33 (2006).
45. Fujita, Y. et al. Zyxin is a novel interacting partner for SIRT1. BMC Cell Biol 10, 6 (2009).
46. Kim, S. C. et al. Substrate and functional diversity of lysine acetylation revealed by a proteomics survey. Mol Cell 23, 607-18 (2006).
47. Sadoul, K., Wang, J., Diagouraga, B. & Khochbin, S. The tale of protein lysine acetylation in the cytoplasm. J Biomed Biotechnol 2011, 970382 (2011).
48. Schubert, H. L. et al. Structure of an actin-related subcomplex of the SWI/SNF chromatin remodeler. Proc Natl Acad Sci USA 110, 3345-50 (2013).
49. Rando, O. J., Zhao, K., Janmey, P. & Crabtree, G. R. Phosphatidylinositol-dependent actin filament binding by the SWI/SNF-like BAF chromatin remodeling complex. Proc Natl Acad Sci USA 99, 2824-9 (2002).
50. Miyamoto, K., Pasque, V., Jullien, J. & Gurdon, J. B. Nuclear actin polymerization is required for transcriptional reprogramming of Oct4 by oocytes. Genes Dev 25, 946-58 (2011).
51. Vartiainen, M. K., Guettler, S., Larijani, B. & Treisman, R. Nuclear actin regulates dynamic subcellular localization and activity of the SRF cofactor MAL. Science 316, 1749-52 (2007).
52. Baarlink, C., Wang, H. & Grosse, R. Nuclear actin network assembly by formins regulates the SRF coactivator MAL. Science 340, 864-7 (2013).
53. Belin, B. J., Cimini, B. A., Blackburn, E. H. & Mullins, R. D. Visualization of actin filaments and monomers in somatic cell nuclei. Mol Biol Cell 24, 982-94 (2013).