Core Fucosylation on T Cells, Required for Activation of T-Cell Receptor Signaling and Induction of Colitis in Mice, Is Increased in Patients with Inflammatory Bowel Disease

Gastroenterology

Volumn 150, Issue 7, 2016, Pages 1620-1632

  Fujii, Hironobu ^a   Shinzaki, Shinichiro ^b   Iijima, Hideki ^b   Wakamatsu, Kana ^a   Iwamoto, Chizuru ^a   Sobajima, Tomoaki ^a   Kuwahara, Ryusuke ^b   Hiyama, Satoshi ^b   Hayashi, Yoshito ^b   Takamatsu, Shinji ^a   Uozumi, Naofumi ^a   Kamada, Yoshihiro ^a,b   Tsujii, Masahiko ^b   Taniguchi, Naoyuki ^c   Takehara, Tetsuo ^b   Miyoshi, Eiji ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c RIKEN   (Japan)

Author keywords

Activation; Glycosylation; Oligosaccharide; T Cell Signaling

Indexed keywords

CD28 ANTIGEN; CD4 ANTIGEN; FLOTILLIN 1; FUCOSE; FUCOSYLTRANSFERASE; L SELECTIN; MESSENGER RNA; RAG2 PROTEIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR RELA; GLYCOPROTEIN 6-ALPHA-L-FUCOSYLTRANSFERASE;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CROHN DISEASE; CYTOKINE PRODUCTION; DISEASE COURSE; DISEASE SEVERITY; FEMALE; FLOW CYTOMETRY; FUCOSYLATION; IMMUNOFLUORESCENCE; INTESTINAL TISSUE; INTESTINE BIOPSY; INTRACELLULAR SIGNALING; LIPID RAFT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN CELL; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH2 CELL; TRINITROBENZENE SULFONIC ACID-INDUCED COLITIS; ULCERATIVE COLITIS; ADULT; ANIMAL; BIOPSY; CASE CONTROL STUDY; CHEMICALLY INDUCED; COLITIS; HUMAN; IMMUNOLOGY; INTESTINE; LYMPHOCYTE ACTIVATION; MALE; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ADOPTIVE TRANSFER; ADULT; ANIMALS; BIOPSY; CASE-CONTROL STUDIES; COLITIS; COLITIS, ULCERATIVE; CROHN DISEASE; FEMALE; FUCOSE; FUCOSYLTRANSFERASES; HUMANS; INTESTINES; LYMPHOCYTE ACTIVATION; MALE; MICE; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 84975842440     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2016.03.002     Document Type: Article

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