Vitrectomy before Intravitreal Injection of AAV2/2 Vector Promotes Efficient Transduction of Retinal Ganglion Cells in Dogs and Nonhuman Primates

Human Gene Therapy Methods

Volumn 27, Issue 3, 2016, Pages 122-134

  Tshilenge, Kizito Tshitoko ^a   Ameline, Baptiste ^a   Weber, Michel ^b   Mendes Madeira, Alexandra ^a   Nedellec, Steven ^c   Biget, Marine ^a   Provost, Nathalie ^a   Libeau, Lyse ^a   Blouin, Véronique ^a   Deschamps, Jack Yves ^d   Le Meur, Guylène ^b   Colle, Marie Anne ^d   Moullier, Philippe ^a,e   Pichard, Virginie ^a   Rolling, Fabienne ^a  

^a UNIVERSITÉ DE NANTES   (France)

^b NANTES UNIVERSITY HOSPITAL   (France)

^c Recombinant Protein Production Facility Federative Research Structure François Bonamy   (France)

^d LUNAM UNIVERSITÉ   (France)

^e UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; PARVOVIRUS VECTOR; GREEN FLUORESCENT PROTEIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEAGLE; CELL DENSITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EYE ENUCLEATION; EYE PHOTOGRAPHY; FEMALE; GENE EXPRESSION; GENETIC TRANSDUCTION; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; MACACA FASCICULARIS; MALE; NONHUMAN; OPTIC NERVE; PRIORITY JOURNAL; RAT; RETINA AMACRINE CELL; RETINA GANGLION CELL; RETINA NERVE CELL; VIRAL GENE DELIVERY SYSTEM; VITRECTOMY; ANIMAL; DEPENDOPARVOVIRUS; DOG; GENE THERAPY; GENE TRANSFER; GENE VECTOR; GENETICS; HUMAN; INTRAVITREAL DRUG ADMINISTRATION; MACACA; PATHOLOGY; RETINA; THERAPEUTIC USE; TRANSPLANTATION;

ANIMALS; DEPENDOVIRUS; DOGS; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HUMANS; INTRAVITREAL INJECTIONS; MACACA; RETINA; RETINAL GANGLION CELLS; TRANSDUCTION, GENETIC; VITRECTOMY;

EID: 84975743906     PISSN: 19466536     EISSN: 19466544     Source Type: Journal    
DOI: 10.1089/hgtb.2016.034     Document Type: Article

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