Let-7a suppresses macrophage infiltrations and malignant phenotype of Ewing sarcoma via STAT3/NF-κB positive regulatory circuit

Cancer Letters

Volumn 374, Issue 2, 2016, Pages 192-201

  Zhang, Zhongzu ^a,b   Li, Yunyun ^b   Huang, Lu ^c   Xiao, Qianren ^a   Chen, Xiang ^a   Zhong, Junlong ^a   Chen, Yiwei ^a   Yang, Dong ^a   Han, Zhimin ^a   Shu, Yong ^a   Dai, Min ^a   Cao, Kai ^a  

^a NANCHANG UNIVERSITY   (China)

^b CHONGQING MEDICAL UNIVERSITY   (China)

^c Department of Pharmacy   (China)

Author keywords

Ewing sarcoma; Let 7a; MicroRNA; Nuclear factor kappa B (NF B); Signal transducer and activator of transcription 3 (STAT3); TAMs

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MICRORNA; MICRORNA LET 7A; STAT3 PROTEIN; UNCLASSIFIED DRUG; MIRNLET7 MICRORNA, HUMAN; STAT3 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; EWING SARCOMA; FEEDBACK SYSTEM; GENE FUNCTION; GENE OVEREXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MACROPHAGE INFILTRATION; MONOCYTE; MOUSE; NONHUMAN; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TUMOR CELL; TUMOR XENOGRAFT; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; FEMALE; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; IMMUNOLOGY; MACROPHAGE; METABOLISM; NUDE MOUSE; PATHOLOGY; TUMOR CELL LINE; XENOGRAFT;

ANIMALS; CELL LINE, TUMOR; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HETEROGRAFTS; HUMANS; MACROPHAGES; MICE; MICE, NUDE; MICRORNAS; NF-KAPPA B; SARCOMA, EWING; STAT3 TRANSCRIPTION FACTOR; TRANSFECTION;

EID: 84975678616     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2016.02.027     Document Type: Article

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