-
2
-
-
3042736080
-
Studies of the isoprenoid-mediated inhibition of mevalonate synthesis applied to cancer chemotherapy and chemoprevention
-
Mo H, Elson CE. Studies of the isoprenoid-mediated inhibition of mevalonate synthesis applied to cancer chemotherapy and chemoprevention. Exp Biol Med (Maywood) 2004; 229: 567-585.
-
(2004)
Exp Biol Med (Maywood)
, vol.229
, pp. 567-585
-
-
Mo, H.1
Elson, C.E.2
-
4
-
-
0021204120
-
Evidence for post-translational incorporation of a product of mevalonic acid into Swiss 3T3 cell proteins
-
Schmidt RA, Schneider CJ, Glomset JA. Evidence for post-translational incorporation of a product of mevalonic acid into Swiss 3T3 cell proteins. J Biol Chem 1984; 259: 10175-10180.
-
(1984)
J Biol Chem
, vol.259
, pp. 10175-10180
-
-
Schmidt, R.A.1
Schneider, C.J.2
Glomset, J.A.3
-
5
-
-
0034091677
-
Inhibition of N-methyl-N-nitrosourea- and 7,12-dimethylbenz[a] anthracene-induced rat mammary tumorigenesis by dietary cholesterol is independent of Ha-Ras mutations
-
El-Sohemy A, Archer MC. Inhibition of N-methyl-N-nitrosourea- and 7,12-dimethylbenz[a] anthracene-induced rat mammary tumorigenesis by dietary cholesterol is independent of Ha-Ras mutations. Carcinogenesis 2000; 21: 827-831.
-
(2000)
Carcinogenesis
, vol.21
, pp. 827-831
-
-
El-Sohemy, A.1
Archer, M.C.2
-
6
-
-
0027451612
-
Importance of mevalonate-derived products in the control of HMG-CoA reductase activity and growth of human lung adenocarcinoma cell line A549
-
Bennis F, Favre G, Le Gaillard F, Soula G. Importance of mevalonate-derived products in the control of HMG-CoA reductase activity and growth of human lung adenocarcinoma cell line A549. Int J Cancer 1993; 55: 640-645.
-
(1993)
Int J Cancer
, vol.55
, pp. 640-645
-
-
Bennis, F.1
Favre, G.2
Le Gaillard, F.3
Soula, G.4
-
7
-
-
0025814690
-
Vivo regulation of human leukocyte 3-hydroxy-3-methylglutaryl coenzyme A reductase: Increased enzyme protein concentration and catalytic efficiency in human leukemia and lymphoma
-
Harwood Jr HJ, Alvarez IM, Noyes WD, Stacpoole PW. In vivo regulation of human leukocyte 3-hydroxy-3-methylglutaryl coenzyme A reductase: increased enzyme protein concentration and catalytic efficiency in human leukemia and lymphoma. J Lipid Res 1991; 32: 1237-1252.
-
(1991)
J Lipid Res
, vol.32
, pp. 1237-1252
-
-
Harwood, Jr.H.J.1
Alvarez, I.M.2
Noyes, W.D.3
Stacpoole, P.W.4
-
8
-
-
0025291799
-
Increase in the active form of 3-hydroxy-3-methylglutaryl coenzyme A reductase in human hepatocellular carcinoma: Possible mechanism for alteration of cholesterol biosynthesis
-
Kawata S, Takaishi K, Nagase T, Ito N, Matsuda Y, Tamura S et al. Increase in the active form of 3-hydroxy-3-methylglutaryl coenzyme A reductase in human hepatocellular carcinoma: Possible mechanism for alteration of cholesterol biosynthesis. Cancer Res 1990; 50: 3270-3273.
-
(1990)
Cancer Res
, vol.50
, pp. 3270-3273
-
-
Kawata, S.1
Takaishi, K.2
Nagase, T.3
Ito, N.4
Matsuda, Y.5
Tamura, S.6
-
9
-
-
4043114237
-
Mevalonate promotes the growth of tumors derived from human cancer cells in vivo and stimulates proliferation in vitro with enhanced cyclindependent kinase-2 activity
-
Duncan RE, El-Sohemy A, Archer MC. Mevalonate promotes the growth of tumors derived from human cancer cells in vivo and stimulates proliferation in vitro with enhanced cyclindependent kinase-2 activity. J Biol Chem 2004; 279: 33079-33084.
-
(2004)
J Biol Chem
, vol.279
, pp. 33079-33084
-
-
Duncan, R.E.1
El-Sohemy, A.2
Archer, M.C.3
-
10
-
-
77950509620
-
A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseases
-
Hirsch HA, Iliopoulos D, Joshi A, Zhang Y, Jaeger SA, Bulyk M et al. A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseases. Cancer Cell 2010; 17: 348-361.
-
(2010)
Cancer Cell
, vol.17
, pp. 348-361
-
-
Hirsch, H.A.1
Iliopoulos, D.2
Joshi, A.3
Zhang, Y.4
Jaeger, S.A.5
Bulyk, M.6
-
12
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144: 646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
14
-
-
79955751752
-
Metabolic regulation by p53
-
Maddocks OD, Vousden KH. Metabolic regulation by p53. J Mol Med 2011; 89: 237-245.
-
(2011)
J Mol Med
, vol.89
, pp. 237-245
-
-
Maddocks, O.D.1
Vousden, K.H.2
-
15
-
-
0029953888
-
HMG-CoA reductase inhibitors: Role in normal and malignant cells
-
Larsson O. HMG-CoA reductase inhibitors: role in normal and malignant cells. Crit Rev Oncol Hematol 1996; 22: 197-212.
-
(1996)
Crit Rev Oncol Hematol
, vol.22
, pp. 197-212
-
-
Larsson, O.1
-
16
-
-
0026607503
-
Cholesterol inhibition, cancer, and chemotherapy
-
Buchwald H. Cholesterol inhibition, cancer, and chemotherapy. Lancet 1992; 339: 1154-1156.
-
(1992)
Lancet
, vol.339
, pp. 1154-1156
-
-
Buchwald, H.1
-
17
-
-
0036258111
-
The IARC TP53 database: New online mutation analysis and recommendations to users
-
Olivier M, Eeles R, Hollstein M, Khan MA, Harris CC, Hainaut P. The IARC TP53 database: new online mutation analysis and recommendations to users. Hum Mutat 2002; 19: 607-614.
-
(2002)
Hum Mutat
, vol.19
, pp. 607-614
-
-
Olivier, M.1
Eeles, R.2
Hollstein, M.3
Khan, M.A.4
Harris, C.C.5
Hainaut, P.6
-
18
-
-
59349086106
-
P53 transcriptional activities: A general overview and some thoughts
-
Millau JF, Bastien N, Drouin R. p53 transcriptional activities: a general overview and some thoughts. Mutat Res 2009; 681: 118-133.
-
(2009)
Mutat Res
, vol.681
, pp. 118-133
-
-
Millau, J.F.1
Bastien, N.2
Drouin, R.3
-
19
-
-
77955418479
-
The C terminus of p53 binds the N-terminal domain of MDM2
-
Poyurovsky MV, Katz C, Laptenko O, Beckerman R, Lokshin M, Ahn J et al. The C terminus of p53 binds the N-terminal domain of MDM2. Nat Struct Mol Biol 2010; 17: 982-989.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 982-989
-
-
Poyurovsky, M.V.1
Katz, C.2
Laptenko, O.3
Beckerman, R.4
Lokshin, M.5
Ahn, J.6
-
20
-
-
0037173059
-
The p53MH algorithm and its application in detecting p53-responsive genes
-
Hoh J, Jin S, Parrado T, Edington J, Levine AJ, Ott J. The p53MH algorithm and its application in detecting p53-responsive genes. Proc Natl Acad Sci USA 2002; 99: 8467-8472.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 8467-8472
-
-
Hoh, J.1
Jin, S.2
Parrado, T.3
Edington, J.4
Levine, A.J.5
Ott, J.6
-
21
-
-
0028971143
-
MatInd and MatInspector: New fast and versatile tools for detection of consensus matches in nucleotide sequence data
-
Quandt K, Frech K, Karas H, Wingender E, Werner T. MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res 1995; 23: 4878-4884.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 4878-4884
-
-
Quandt, K.1
Frech, K.2
Karas, H.3
Wingender, E.4
Werner, T.5
-
22
-
-
84862908644
-
Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway
-
Freed-Pastor WA, Mizuno H, Zhao X, Langerød A, Moon SH, Rodriguez-Barrueco R et al. Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway. Cell 2012; 148: 244-258.
-
(2012)
Cell
, vol.148
, pp. 244-258
-
-
Freed-Pastor, W.A.1
Mizuno, H.2
Zhao, X.3
Langerød, A.4
Moon, S.H.5
Rodriguez-Barrueco, R.6
-
23
-
-
0030027536
-
Lipid metabolism as a target for brain cancer therapy: Synergistic activity of lovastatin and sodium phenylacetate against human glioma cells
-
Prasanna P, Thibault A, Liu L, Samid D. Lipid metabolism as a target for brain cancer therapy: Synergistic activity of lovastatin and sodium phenylacetate against human glioma cells. J Neurochem 1996; 66: 710-716.
-
(1996)
J Neurochem
, vol.66
, pp. 710-716
-
-
Prasanna, P.1
Thibault, A.2
Liu, L.3
Samid, D.4
-
24
-
-
77956989082
-
Dysregulation of the mevalonate pathway promotes transformation
-
Clendening JW, Pandyra A, Boutros PC, El Ghamrasni S, Khosravi F, Trentin GA et al. Dysregulation of the mevalonate pathway promotes transformation. Proc Natl Acad Sci USA 2010; 107: 15051-15056.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 15051-15056
-
-
Clendening, J.W.1
Pandyra, A.2
Boutros, P.C.3
El Ghamrasni, S.4
Khosravi, F.5
Trentin, G.A.6
-
25
-
-
26444519176
-
Lipid synthetic transcription factor SREBP-1a activates p21WAF1/CIP1, a universal cyclindependent kinase inhibitor
-
Inoue N, Shimano H, Nakakuki M, Matsuzaka T, Nakagawa Y, Yamamoto T, Sato R et al. Lipid synthetic transcription factor SREBP-1a activates p21WAF1/CIP1, a universal cyclindependent kinase inhibitor. Mol Cell Biol 2005; 25: 8938-8947.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 8938-8947
-
-
Inoue, N.1
Shimano, H.2
Nakakuki, M.3
Matsuzaka, T.4
Nakagawa, Y.5
Yamamoto, T.6
Sato, R.7
-
26
-
-
79960459422
-
Cholesterol metabolism in neurons and astrocytes
-
Pfrieger FW, Ungerer N. Cholesterol metabolism in neurons and astrocytes. Prog Lipid Res 2011; 50: 357-371.
-
(2011)
Prog Lipid Res
, vol.50
, pp. 357-371
-
-
Pfrieger, F.W.1
Ungerer, N.2
-
27
-
-
24744453768
-
Identification of novel p53 target genes in ionizing radiation response
-
Jen KY, Cheung VG. Identification of novel p53 target genes in ionizing radiation response. Cancer Res 2005; 65: 7666-7673.
-
(2005)
Cancer Res
, vol.65
, pp. 7666-7673
-
-
Jen, K.Y.1
Cheung, V.G.2
-
28
-
-
84055190692
-
Distinct p53 genomic binding patterns in normal and cancer-derived human cells
-
Botcheva K, McCorkle SR, McCombie WR, Dunn JJ, Anderson CW. Distinct p53 genomic binding patterns in normal and cancer-derived human cells. Cell Cycle 2011; 10: 4237-4249.
-
(2011)
Cell Cycle
, vol.10
, pp. 4237-4249
-
-
Botcheva, K.1
McCorkle, S.R.2
McCombie, W.R.3
Dunn, J.J.4
Anderson, C.W.5
-
29
-
-
56649117454
-
Wild-type p53 in cancer cells: When a guardian turns into a blackguard
-
Kim E, Giese A, Deppert W. Wild-type p53 in cancer cells: when a guardian turns into a blackguard. Biochem Pharmacol 2009; 77: 11-20.
-
(2009)
Biochem Pharmacol
, vol.77
, pp. 11-20
-
-
Kim, E.1
Giese, A.2
Deppert, W.3
-
30
-
-
34547935761
-
Oren M living with p53, dying of p53
-
Aylon Y. Oren M living with p53, dying of p53. Cell 2007; 130: 597-600.
-
(2007)
Cell
, vol.130
, pp. 597-600
-
-
Aylon, Y.1
-
31
-
-
84878632932
-
Atorvastatin suppresses glioma invasion and migration by reducing microglial MT1-MMP expression
-
Yongjun Y, Shuyun H, Lei C, Xiangrong C, Zhilin Y, Yiquan K. Atorvastatin suppresses glioma invasion and migration by reducing microglial MT1-MMP expression. J Neuroimmunol 2013; 260: 1-8.
-
(2013)
J Neuroimmunol
, vol.260
, pp. 1-8
-
-
Yongjun, Y.1
Shuyun, H.2
Lei, C.3
Xiangrong, C.4
Zhilin, Y.5
Yiquan, K.6
-
32
-
-
84862835220
-
Drug resistance in glioblastoma: A mini review
-
Haar CP, Hebbar P, Wallace 4th GC , Das A, Vandergrift 3rd WA , Smith JA et al. Drug resistance in glioblastoma: a mini review. Neurochem Res 2012; 37: 1192-1200.
-
(2012)
Neurochem Res.
, vol.37
, pp. 1192-1200
-
-
Haar, C.P.1
Hebbar, P.2
Wallace, G.C.3
Das, A.4
Vandergrift, W.A.5
Smith, J.A.6
-
33
-
-
37549042449
-
Differential sensitivity of malignant glioma cells to methylating and chloroethylating anticancer drugs: P53 determines the switch by regulating xpc, ddb2, and DNA double-strand breaks
-
Batista LF, Roos WP, Christmann M, Menck CF, Kaina B. Differential sensitivity of malignant glioma cells to methylating and chloroethylating anticancer drugs: P53 determines the switch by regulating xpc, ddb2, and DNA double-strand breaks. Cancer Res 2007; 67: 11886-11895.
-
(2007)
Cancer Res.
, vol.67
, pp. 11886-11895
-
-
Batista, L.F.1
Roos, W.P.2
Christmann, M.3
Menck, C.F.4
Kaina, B.5
-
34
-
-
33645105856
-
O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells
-
Hermisson M, Klumpp A, Wick W, Wischhusen J, Nagel G, Roos W et al. O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells. J Neurochem 2006; 96: 766-776.
-
(2006)
J Neurochem
, vol.96
, pp. 766-776
-
-
Hermisson, M.1
Klumpp, A.2
Wick, W.3
Wischhusen, J.4
Nagel, G.5
Roos, W.6
-
35
-
-
84876092563
-
Zoledronic acid restores doxorubicin chemosensitivity and immunogenic cell death in multidrug-resistant human cancer cells
-
Riganti C, Castella B, Kopecka J, Campia I, Coscia M et al. Zoledronic acid restores doxorubicin chemosensitivity and immunogenic cell death in multidrug-resistant human cancer cells. PLOS One 2013; 8: e60975.
-
(2013)
PLOS One
, vol.8
, pp. e60975
-
-
Riganti, C.1
Castella, B.2
Kopecka, J.3
Campia, I.4
Coscia, M.5
-
36
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) methods
-
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) methods. Methods 2001; 25: 402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
37
-
-
0025040233
-
Suppression of human colorectal carcinoma cell growth by wild-type p53
-
Baker SJ, Markowitz S, Fearon ER, Willson JK, Vogelstein B. Suppression of human colorectal carcinoma cell growth by wild-type p53. Science 1990; 249: 912-915.
-
(1990)
Science
, vol.249
, pp. 912-915
-
-
Baker, S.J.1
Markowitz, S.2
Fearon, E.R.3
Willson, J.K.4
Vogelstein, B.5
-
38
-
-
0034847978
-
Induction of p53-independent apoptosis by simian virus 40 small t antigen
-
Gjoerup O, Zaveri D, Roberts TM. Induction of p53-independent apoptosis by simian virus 40 small t antigen. J Virol 2001; 75: 9142-9155.
-
(2001)
J Virol
, vol.75
, pp. 9142-9155
-
-
Gjoerup, O.1
Zaveri, D.2
Roberts, T.M.3
-
39
-
-
0029020355
-
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in FRTL-5 cells. II. Downregulation by v-K-ras oncogene
-
Perillo B, Tedesco I, Laezza C, Santillo M, Romano A, Aloj SM et al. Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in FRTL-5 cells. II. Downregulation by v-K-ras oncogene. J Biol Chem 1995; 270: 15237-15241.
-
(1995)
J Biol Chem
, vol.270
, pp. 15237-15241
-
-
Perillo, B.1
Tedesco, I.2
Laezza, C.3
Santillo, M.4
Romano, A.5
Aloj, S.M.6
|