메뉴 건너뛰기




Volumn 21, Issue 4, 2000, Pages 827-831

Inhibition of N-methyl-N-nitrosourea- and 7,12-dimethylbenz[a] anthracene-induced rat mammary tumorigenesis by dietary cholesterol is independent of Ha-ras mutations

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; DIMETHYLBENZ[A]ANTHRACENE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; ISOPRENOID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; METHYLNITROSOUREA; MEVALONIC ACID; RAS PROTEIN;

EID: 0034091677     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/21.4.827     Document Type: Article
Times cited : (38)

References (52)
  • 1
    • 0026583808 scopus 로고
    • Relationship between dietary fat and experimental mammary tumorigenesis: A review and critique
    • Welsch, C.W. (1992) Relationship between dietary fat and experimental mammary tumorigenesis: a review and critique. Cancer Res., 52 (suppl.), 2040s-2048s.
    • (1992) Cancer Res. , vol.52 , Issue.SUPPL.
    • Welsch, C.W.1
  • 2
    • 0030853609 scopus 로고    scopus 로고
    • Effect of different types and amounts of fat on the development of mammary tumors in rodents: A review
    • Fay, M.P., Freedman, L.S., Clifford, C.K. and Midthune, D.N. (1997) Effect of different types and amounts of fat on the development of mammary tumors in rodents: a review. Cancer Res., 57, 3979-3988.
    • (1997) Cancer Res. , vol.57 , pp. 3979-3988
    • Fay, M.P.1    Freedman, L.S.2    Clifford, C.K.3    Midthune, D.N.4
  • 3
    • 0030664310 scopus 로고    scopus 로고
    • Molecular studies on the role of dietary fat and cholesterol in breast cancer induction
    • Archer, M.C., El-Sohemy, A., Stephen, L.L. and Badawi, A.F. (1997) Molecular studies on the role of dietary fat and cholesterol in breast cancer induction. Adv. Exp. Med. Biol., 422, 39-46.
    • (1997) Adv. Exp. Med. Biol. , vol.422 , pp. 39-46
    • Archer, M.C.1    El-Sohemy, A.2    Stephen, L.L.3    Badawi, A.F.4
  • 4
    • 0030007102 scopus 로고    scopus 로고
    • Inhibition of rat mammary tumorigenesis by dietary cholesterol
    • El-Sohemy, A., Bruce, W.R. and Archer, M.C. (1996) Inhibition of rat mammary tumorigenesis by dietary cholesterol. Carcinogenesis, 17, 159-162.
    • (1996) Carcinogenesis , vol.17 , pp. 159-162
    • El-Sohemy, A.1    Bruce, W.R.2    Archer, M.C.3
  • 5
    • 0022549920 scopus 로고
    • A receptor-mediated pathway for cholesterol homeostasis
    • Brown, M.S. and Goldstein, J.L. (1986) A receptor-mediated pathway for cholesterol homeostasis. Science, 232, 34-47.
    • (1986) Science , vol.232 , pp. 34-47
    • Brown, M.S.1    Goldstein, J.L.2
  • 7
    • 0019135838 scopus 로고
    • Multivalent feedback regulation of HMG CoA reductase: A control mechanism coordinating isoprenoid synthesis and cell growth
    • Brown, M.S. and Goldstein, J.L. (1980) Multivalent feedback regulation of HMG CoA reductase: a control mechanism coordinating isoprenoid synthesis and cell growth. J. Lipid Res., 21, 505-517.
    • (1980) J. Lipid Res. , vol.21 , pp. 505-517
    • Brown, M.S.1    Goldstein, J.L.2
  • 8
    • 0031409639 scopus 로고    scopus 로고
    • Anti-carcinogenic activity of simvastatin during the promotion phase of radiation-induced mammary tumorigenesis of rats
    • Inano, H., Suzuki, K., Onoda, M. and Wakabayashi, K. (1997) Anti-carcinogenic activity of simvastatin during the promotion phase of radiation-induced mammary tumorigenesis of rats. Carcinogenesis, 18, 1723-1727.
    • (1997) Carcinogenesis , vol.18 , pp. 1723-1727
    • Inano, H.1    Suzuki, K.2    Onoda, M.3    Wakabayashi, K.4
  • 9
    • 0031784485 scopus 로고    scopus 로고
    • Reduction of mouse mammary tumor formation and metastasis by lovastatin, an inhibitor of the mevalonate pathway of cholesterol synthesis
    • Alonso, D.F., Farina, H.G., Skilton, G., Gabri, M.R., De Lorenzo, M.S. and Gomez, D.E. (1998) Reduction of mouse mammary tumor formation and metastasis by lovastatin, an inhibitor of the mevalonate pathway of cholesterol synthesis. Br. Cancer Res. Treat., 50, 83-93.
    • (1998) Br. Cancer Res. Treat. , vol.50 , pp. 83-93
    • Alonso, D.F.1    Farina, H.G.2    Skilton, G.3    Gabri, M.R.4    De Lorenzo, M.S.5    Gomez, D.E.6
  • 10
    • 0027215178 scopus 로고
    • Isoprenoid regulation of cell growth: Identification of mevalonte-labelled compounds inducing DNA synthesis in human breast cancer cells depleted of serum and mevalonate
    • Wejde, J., Carlberg, M., Hjertman, M. and Larsson, O. (1993) Isoprenoid regulation of cell growth: identification of mevalonte-labelled compounds inducing DNA synthesis in human breast cancer cells depleted of serum and mevalonate. J. Cell. Physiol., 155, 539-548.
    • (1993) J. Cell. Physiol. , vol.155 , pp. 539-548
    • Wejde, J.1    Carlberg, M.2    Hjertman, M.3    Larsson, O.4
  • 11
    • 0028326155 scopus 로고
    • Effects of isoprenoids on growth of normal human mammary epithelial cells and breast cancer cells in vitro
    • Larsson, O. (1994) Effects of isoprenoids on growth of normal human mammary epithelial cells and breast cancer cells in vitro. Anticancer Res., 14, 123-128.
    • (1994) Anticancer Res. , vol.14 , pp. 123-128
    • Larsson, O.1
  • 12
    • 0019305204 scopus 로고
    • Relation of cholesterol and mevalonic acid to the cell cycle in smooth muscle and swiss 3T3 cells stimulated to divide by platelet-derived growth factor
    • Habenicht, A.J.R., Glomset, J. A. and Ross, R. (1980) Relation of cholesterol and mevalonic acid to the cell cycle in smooth muscle and swiss 3T3 cells stimulated to divide by platelet-derived growth factor. J. Biol. Chem., 255, 5134-5140.
    • (1980) J. Biol. Chem. , vol.255 , pp. 5134-5140
    • Habenicht, A.J.R.1    Glomset, J.A.2    Ross, R.3
  • 14
    • 0024376173 scopus 로고
    • Ras oncogenes in human cancer: A review
    • Bos, J.L. (1989) ras oncogenes in human cancer: a review. Cancer Res., 49, 4682-4689.
    • (1989) Cancer Res. , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 16
    • 0030992130 scopus 로고    scopus 로고
    • Protein prenylation, et cetera: Signal transduction in two dimensions
    • Gelb, M.H. (1997) Protein prenylation, et cetera: signal transduction in two dimensions. Science, 275, 1750-1751.
    • (1997) Science , vol.275 , pp. 1750-1751
    • Gelb, M.H.1
  • 17
    • 0025120211 scopus 로고
    • Regulation of the mevalonate pathway
    • Goldstein, J.L. and Brown, M.S. (1990) Regulation of the mevalonate pathway. Nature. 343, 425-430.
    • (1990) Nature , vol.343 , pp. 425-430
    • Goldstein, J.L.1    Brown, M.S.2
  • 19
    • 0027362493 scopus 로고
    • Farnesylamine: An inhibitor of farnesylation and growth of ras-transformed cells
    • Kothapalli, R., Guthrie, N., Chambers, A.F. and Carroll, K.K. (1993) Farnesylamine: an inhibitor of farnesylation and growth of ras-transformed cells. Lipids, 28, 969-973.
    • (1993) Lipids , vol.28 , pp. 969-973
    • Kothapalli, R.1    Guthrie, N.2    Chambers, A.F.3    Carroll, K.K.4
  • 21
    • 0028898579 scopus 로고
    • Ras farnesyltransferase inhibitors suppress the phenotype resulting from an activated ras mutation in Caenorhabditis elegans
    • Hara, M. and Han, M. (1995) Ras farnesyltransferase inhibitors suppress the phenotype resulting from an activated ras mutation in Caenorhabditis elegans. Proc. Natl Acad. Sci. USA, 92, 3333-3337.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 3333-3337
    • Hara, M.1    Han, M.2
  • 22
    • 0001429857 scopus 로고
    • Chemically-induced mammary gland tumors in rats: Modulation by dietary fat
    • Ip, C., Birt, D.F., Rogers, A.E. and Mettlin, M. (eds) Alan R. Liss, New York, NY
    • Rogers, A.E. and Lee, S.Y. (1988) Chemically-induced mammary gland tumors in rats: modulation by dietary fat. In Ip, C., Birt, D.F., Rogers, A.E. and Mettlin, M. (eds) Dietary Fat and Cancer. Alan R. Liss, New York, NY, pp. 255-269.
    • (1988) Dietary Fat and Cancer , pp. 255-269
    • Rogers, A.E.1    Lee, S.Y.2
  • 23
    • 0021871265 scopus 로고
    • Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats
    • Zarbl, H., Sukumar, S., Arthur, A.V., Martin-Zanca, D. and Barbacid, M. (1985) Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats. Nature, 315, 382-385.
    • (1985) Nature , vol.315 , pp. 382-385
    • Zarbl, H.1    Sukumar, S.2    Arthur, A.V.3    Martin-Zanca, D.4    Barbacid, M.5
  • 24
    • 0021074016 scopus 로고
    • Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1-locus by single point mutations
    • Sukumar, S., Notario, V., Martin-Zanca, D. and Barbacid, M. (1983) Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1-locus by single point mutations. Nature. 3116, 658-661.
    • (1983) Nature , vol.3116 , pp. 658-661
    • Sukumar, S.1    Notario, V.2    Martin-Zanca, D.3    Barbacid, M.4
  • 26
    • 0026619185 scopus 로고
    • The ras/cholesterol connection: Implications for ras oncogenicity
    • Cox, A.D. and Der, C.J. (1992) The ras/cholesterol connection: implications for ras oncogenicity. Crit. Rev. Oncog., 3, 365-400.
    • (1992) Crit. Rev. Oncog. , vol.3 , pp. 365-400
    • Cox, A.D.1    Der, C.J.2
  • 27
    • 0027487229 scopus 로고
    • AIN-93G purified diets for laboratory rodents: Final report of the American Institute of Nutrition ad Hoc Writing Committee on the reformulation of the AIN-76A rodent diet
    • Reeves, P.G., Nielsen, F.H. and Fahey, G.C.J. (1993) AIN-93G purified diets for laboratory rodents: final report of the American Institute of Nutrition ad Hoc Writing Committee on the Reformulation of the AIN-76A Rodent Diet. J. Nutr. 123, 1939-1951.
    • (1993) J. Nutr. , vol.123 , pp. 1939-1951
    • Reeves, P.G.1    Nielsen, F.H.2    Fahey, G.C.J.3
  • 28
    • 0026770144 scopus 로고
    • Effect of carcinogen dose and age at administration on induction of mammary carcinogenesis by 1-methyl-1-nitrosourea
    • Thompson, H.J., Adlakha, H. and Singh, M. (1992) Effect of carcinogen dose and age at administration on induction of mammary carcinogenesis by 1-methyl-1-nitrosourea. Carcinogenesis, 13, 1535-1539.
    • (1992) Carcinogenesis , vol.13 , pp. 1535-1539
    • Thompson, H.J.1    Adlakha, H.2    Singh, M.3
  • 29
    • 0032744826 scopus 로고    scopus 로고
    • Regulation of mevalonate synthesis in LDL receptor knockout mice fed n-3 or n-6 polyunsaturated fatty acids
    • El-Sohemy, A. and Archer, M.C. (1999) Regulation of mevalonate synthesis in LDL receptor knockout mice fed n-3 or n-6 polyunsaturated fatty acids. Lipids, 34, 1037-1043.
    • (1999) Lipids , vol.34 , pp. 1037-1043
    • El-Sohemy, A.1    Archer, M.C.2
  • 30
    • 0024246142 scopus 로고
    • Oncogene detection at the single cell level
    • Kumar, R. and Barbacid, M. (1988) Oncogene detection at the single cell level. Oncogene, 3, 647-651.
    • (1988) Oncogene , vol.3 , pp. 647-651
    • Kumar, R.1    Barbacid, M.2
  • 33
    • 0026604893 scopus 로고
    • Ha-ras activation in mammary glands of N-methyl-N-nitrosurea-treated rats genetically resistant to mammary adenocarcinogenesis
    • Lu, S.-J. and Archer, M.C. (1992) Ha-ras activation in mammary glands of N-methyl-N-nitrosurea-treated rats genetically resistant to mammary adenocarcinogenesis. Proc. Natl Acad. Sci. USA, 89, 1001-1005.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 1001-1005
    • Lu, S.-J.1    Archer, M.C.2
  • 35
    • 0028229474 scopus 로고
    • Limonene chemoprevention of mammary carcinoma induction following direct in situ transfer of v-Ha-ras
    • Gould, M.N., Moore, C.J., Zhang, R., Wang, B., Kennan, W.S. and Haag, J.D. (1994) Limonene chemoprevention of mammary carcinoma induction following direct in situ transfer of v-Ha-ras. Cancer Res., 54, 3540-3543.
    • (1994) Cancer Res. , vol.54 , pp. 3540-3543
    • Gould, M.N.1    Moore, C.J.2    Zhang, R.3    Wang, B.4    Kennan, W.S.5    Haag, J.D.6
  • 36
    • 0031408652 scopus 로고    scopus 로고
    • Retention of conjugated linoleic acid in the mammary gland is associated with tumor inhibition during the post-initiation phase of carcinogenesis
    • Ip, C., Jiang, C., Thompson, H.J. and Scimeca, J.A. (1997) Retention of conjugated linoleic acid in the mammary gland is associated with tumor inhibition during the post-initiation phase of carcinogenesis. Carcinogenesis, 18, 755-759.
    • (1997) Carcinogenesis , vol.18 , pp. 755-759
    • Ip, C.1    Jiang, C.2    Thompson, H.J.3    Scimeca, J.A.4
  • 37
    • 0025854453 scopus 로고
    • Dietary N-3 fatty acids do not affect induction of Ha-ras mutations in mammary glands of NMU-treated rats
    • Ronai, Z., Lau, Y. and Cohen, L.A. (1991) Dietary N-3 fatty acids do not affect induction of Ha-ras mutations in mammary glands of NMU-treated rats. Mol. Carcinog., 4, 120-128.
    • (1991) Mol. Carcinog. , vol.4 , pp. 120-128
    • Ronai, Z.1    Lau, Y.2    Cohen, L.A.3
  • 38
    • 0025286997 scopus 로고
    • Reduction in the frequency of activated ras oncogenes in rat mammary carcinomas with increasing N-methyl-N-nitrosourea doses or increasing prolactin levels
    • Zhang, R., Haag, J.D. and Gould, M.N. (1990) Reduction in the frequency of activated ras oncogenes in rat mammary carcinomas with increasing N-methyl-N-nitrosourea doses or increasing prolactin levels. Cancer Res., 50, 4286-4290.
    • (1990) Cancer Res. , vol.50 , pp. 4286-4290
    • Zhang, R.1    Haag, J.D.2    Gould, M.N.3
  • 39
    • 0028108019 scopus 로고
    • Effects of excess dietary iron on the promotional stage of 1-methyl-1-nitrosourea-induced mammary carcinogenesis: Pathogenetic characteristics and distribution of iron
    • Singh, M., Lu, J.X., Briggs, S., McGinley, J., Haegele, A. and Thompson, H.J. (1994) Effects of excess dietary iron on the promotional stage of 1-methyl-1-nitrosourea-induced mammary carcinogenesis: pathogenetic characteristics and distribution of iron. Carcinogenesis, 15, 1567-1570.
    • (1994) Carcinogenesis , vol.15 , pp. 1567-1570
    • Singh, M.1    Lu, J.X.2    Briggs, S.3    McGinley, J.4    Haegele, A.5    Thompson, H.J.6
  • 40
    • 0029004911 scopus 로고
    • Ras may mediate mammary cancer promotion by high-fat
    • Lu, J., Jiang, C., Fontaine, S. and Thompson, H.J. (1995) ras may mediate mammary cancer promotion by high-fat. Nutr. Cancer, 23, 283-290.
    • (1995) Nutr. Cancer , vol.23 , pp. 283-290
    • Lu, J.1    Jiang, C.2    Fontaine, S.3    Thompson, H.J.4
  • 42
    • 0023261745 scopus 로고
    • Expression of 3-hydroxy-3-methylglutaryl coenzyme A reductase and LDL-receptor genes in human embryonic tumors and in normal foetal tissues
    • Engstrom, W. and Schofield, P.N. (1987) Expression of 3-hydroxy-3-methylglutaryl coenzyme A reductase and LDL-receptor genes in human embryonic tumors and in normal foetal tissues. Anticancer Res., 7, 337-342.
    • (1987) Anticancer Res. , vol.7 , pp. 337-342
    • Engstrom, W.1    Schofield, P.N.2
  • 43
    • 0000611328 scopus 로고
    • Deletion of cholesterol-negative feedback system in liver tumors
    • Siperstein, M.D. and Fagan, V.M. (1964) Deletion of cholesterol-negative feedback system in liver tumors. Cancer Res., 24, 1108-1115.
    • (1964) Cancer Res. , vol.24 , pp. 1108-1115
    • Siperstein, M.D.1    Fagan, V.M.2
  • 44
    • 0028953585 scopus 로고
    • Cholesterol, cholesterogenesis and cancer
    • Siperstein, M.D. (1995) Cholesterol, cholesterogenesis and cancer. Adv. Exp. Med. Biol., 369, 155-166.
    • (1995) Adv. Exp. Med. Biol. , vol.369 , pp. 155-166
    • Siperstein, M.D.1
  • 45
    • 0027184434 scopus 로고
    • Effect of dietary fat and cholesterol on dimethylbenz[a]anthracene-induced mammary tumorigenesis in Sprague-Dawley rats
    • Nakayama, M., Ju, H.R., Sugano, M. Hirose, N., Ueki, T., Doi, F. and Eynard, A.R. (1993) Effect of dietary fat and cholesterol on dimethylbenz[a]anthracene-induced mammary tumorigenesis in Sprague-Dawley rats. Anticancer Res., 13, 691-698.
    • (1993) Anticancer Res. , vol.13 , pp. 691-698
    • Nakayama, M.1    Ju, H.R.2    Sugano, M.3    Hirose, N.4    Ueki, T.5    Doi, F.6    Eynard, A.R.7
  • 47
    • 0026712866 scopus 로고
    • Koch's Postulates for cholesterol
    • Brown, M.S. and Goldstein, J.L. (1992) Koch's Postulates for cholesterol. Cell, 71, 187-188.
    • (1992) Cell , vol.71 , pp. 187-188
    • Brown, M.S.1    Goldstein, J.L.2
  • 51
    • 0030865838 scopus 로고    scopus 로고
    • Regulation of mevalonate synthesis in rat mammary glands by dietary n-3 and n-6 polyunsaturated fatty acids
    • El-Sohemy, A. and Archer, M.C. (1997) Regulation of mevalonate synthesis in rat mammary glands by dietary n-3 and n-6 polyunsaturated fatty acids. Cancer Res., 57, 3685-3687.
    • (1997) Cancer Res. , vol.57 , pp. 3685-3687
    • El-Sohemy, A.1    Archer, M.C.2
  • 52
    • 0031022228 scopus 로고    scopus 로고
    • Dietary fat and colon cancer: Modulating effect of types and amount of dietary fat on ras-p21 function during promotion and progression stages of colon cancer
    • Singh, J., Hamid, R. and Reddy, B.S. (1997) Dietary fat and colon cancer: modulating effect of types and amount of dietary fat on ras-p21 function during promotion and progression stages of colon cancer. Cancer Res., 57, 253-258.
    • (1997) Cancer Res. , vol.57 , pp. 253-258
    • Singh, J.1    Hamid, R.2    Reddy, B.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.