Altered zinc sensitivity of NMDA receptors harboring clinically-relevant mutations

Neuropharmacology

Volumn 109, Issue , 2016, Pages 196-204

  Serraz, Benjamin ^a   Grand, Teddy ^a   Paoletti, Pierre ^a  

^a PSL RESEARCH UNIVERSITY   (France)

Author keywords

Epilepsy; Glutamate receptor; Mutation; NMDA receptor; Synapse; Zinc

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID RECEPTOR; ZINC; DIZOCILPINE MALEATE; GLUTAMIC ACID; GLYCINE; N-METHYL D-ASPARTATE RECEPTOR SUBTYPE 2A;

ALLOSTERISM; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BENIGN CHILDHOOD EPILEPSY; BRAIN DISEASE; COGNITIVE DEFECT; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG SENSITIVITY; ELECTROPHYSIOLOGY; FEMALE; HUMAN; HUMAN CELL; MISSENSE MUTATION; MOLECULAR BIOLOGY; NONHUMAN; PATCH CLAMP TECHNIQUE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; ROLANDIC EPILEPSY; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; SYNAPTIC TRANSMISSION; ANIMAL; CELL CULTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; GENETICS; HEK293 CELL LINE; METABOLISM; MOUSE; NERVE CELL; PROTEIN SECONDARY STRUCTURE; RAT; XENOPUS LAEVIS;

ANIMALS; CELLS, CULTURED; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GLUTAMIC ACID; GLYCINE; HEK293 CELLS; HUMANS; MICE; MUTATION, MISSENSE; NEURONS; PROTEIN STRUCTURE, SECONDARY; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; XENOPUS LAEVIS; ZINC;

EID: 84975070382     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2016.06.008     Document Type: Article

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