A switch in G protein coupling for type 1 corticotropin-releasing factor receptors promotes excitability in epileptic brains

Science Signaling

Volumn 9, Issue 432, 2016, Pages

  Narla, Chakravarthi ^a,b   Scidmore, Tanner ^a,b   Jeong, Jaymin ^a,b   Everest, Michelle ^a   Chidiac, Peter ^b   Poulter, Michael O ^a,b  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

^b WESTERN UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; GUANINE NUCLEOTIDE BINDING PROTEIN; RGS2 PROTEIN; CORTICOTROPIN RELEASING FACTOR; CORTICOTROPIN RELEASING FACTOR RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; RGS PROTEIN; RGS2 PROTEIN, MOUSE; RGS2 PROTEIN, RAT;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; EPILEPSY; EXCITABILITY; KINDLING; KNOCKOUT MOUSE; MALE; NERVE CELL STIMULATION; NONHUMAN; PRIORITY JOURNAL; PYRIFORM CORTEX; RAT; STRESS; ANIMAL; GENETICS; METABOLISM; MOUSE; PATHOLOGY; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; CORTICOTROPIN-RELEASING HORMONE; EPILEPSY; GTP-BINDING PROTEIN ALPHA SUBUNITS; MALE; MICE; MICE, KNOCKOUT; PIRIFORM CORTEX; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; RGS PROTEINS; SIGNAL TRANSDUCTION;

EID: 84974784749     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.aad8676     Document Type: Article

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