N1-Azinylsulfonyl-1H-indoles: 5-HT6 Receptor Antagonists with Procognitive and Antidepressant-Like Properties

ACS Medicinal Chemistry Letters

Volumn 7, Issue 6, 2016, Pages 618-622

  Zajdel, Paweł ^a   Marciniec, Krzysztof ^b   Satała, Grzegorz ^c   Canale, Vittorio ^a   Kos, Tomasz ^d   Partyka, Anna ^a   Jastrzȩbska Wiȩsek, Magdalena ^a   Wesołowska, Anna ^a   Basińska Ziobroń, Agnieszka ^c   Wójcikowski, Jacek ^c   Daniel, Władysława A ^c   Bojarski, Andrzej J ^c   Popik, Piotr ^a,d  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^b MEDICAL UNIVERSITY OF SILESIA   (Poland)

^c POLISH ACADEMY OF SCIENCES   (Poland)

^d INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

5 HT6 receptor antagonist; Alzheimer's disease; cognitive decline; forced swim test; Isoquinoline quinoline sulfonamides; novel object recognition task; Vogel test

Indexed keywords

4 {[5 METHOXY 3 (1,2,3,6 TETRAHYDROPYRIDIN 4 YL) 1H INDOL 1 YL]SULFONYL]ISOQUINOLINE; ANTIDEPRESSANT AGENT; INDOLE DERIVATIVE; INTEPIRDINE; SEROTONIN 6 ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDEPRESSANT ACTIVITY; ARTICLE; BRAIN-TO-PLASMA RATIO; DRUG SYNTHESIS; FORCED SWIM TEST; IN VIVO STUDY; LOCOMOTION; MEMORY DISORDER; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; VOGEL TEST;

EID: 84974536473     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/acsmedchemlett.6b00056     Document Type: Article

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