메뉴 건너뛰기




Volumn 127, Issue 23, 2016, Pages 2856-2866

MiR-181a negatively regulates NF-κB signaling and affects activated B-cell-like diffuse large B-cell lymphoma pathogenesis

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MICRORNA; MICRORNA 181A; UNCLASSIFIED DRUG; MIRN181 MICRORNA, HUMAN;

EID: 84974518965     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2015-11-680462     Document Type: Article
Times cited : (46)

References (55)
  • 1
    • 33745982067 scopus 로고    scopus 로고
    • Rituximab-CHOP versus CHOP alone or with maintenance rituximab in older patients with diffuse large B-cell lymphoma
    • Habermann TM, Weller EA, Morrison VA, et al. Rituximab-CHOP versus CHOP alone or with maintenance rituximab in older patients with diffuse large B-cell lymphoma. J Clin Oncol. 2006;24(19):3121-3127.
    • (2006) J Clin Oncol. , vol.24 , Issue.19 , pp. 3121-3127
    • Habermann, T.M.1    Weller, E.A.2    Morrison, V.A.3
  • 2
    • 0037165261 scopus 로고    scopus 로고
    • CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma
    • Coiffier B, Lepage E, Briere J, et al. CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma. N Engl J Med. 2002;346(4):235-242.
    • (2002) N Engl J Med. , vol.346 , Issue.4 , pp. 235-242
    • Coiffier, B.1    Lepage, E.2    Briere, J.3
  • 3
    • 0034598746 scopus 로고    scopus 로고
    • Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
    • Alizadeh AA, Eisen MB, Davis RE, et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature. 2000;403(6769):503-511.
    • (2000) Nature , vol.403 , Issue.6769 , pp. 503-511
    • Alizadeh, A.A.1    Eisen, M.B.2    Davis, R.E.3
  • 4
    • 0035905313 scopus 로고    scopus 로고
    • Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells
    • Davis RE, Brown KD, Siebenlist U, Staudt LM. Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells. J Exp Med. 2001;194(12):1861-1874.
    • (2001) J Exp Med. , vol.194 , Issue.12 , pp. 1861-1874
    • Davis, R.E.1    Brown, K.D.2    Siebenlist, U.3    Staudt, L.M.4
  • 5
    • 19944428834 scopus 로고    scopus 로고
    • Small molecule inhibitors of IkappaB kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma defined by gene expression profiling
    • Lam LT, Davis RE, Pierce J, et al. Small molecule inhibitors of IkappaB kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma defined by gene expression profiling. Clin Cancer Res. 2005;11(1):28-40.
    • (2005) Clin Cancer Res. , vol.11 , Issue.1 , pp. 28-40
    • Lam, L.T.1    Davis, R.E.2    Pierce, J.3
  • 7
    • 79551686422 scopus 로고    scopus 로고
    • Oncogenically active MYD88 mutations in human lymphoma
    • Ngo VN, Young RM, Schmitz R, et al. Oncogenically active MYD88 mutations in human lymphoma. Nature. 2011;470(7332):115-119.
    • (2011) Nature , vol.470 , Issue.7332 , pp. 115-119
    • Ngo, V.N.1    Young, R.M.2    Schmitz, R.3
  • 8
    • 41149136296 scopus 로고    scopus 로고
    • Oncogenic CARD11 mutations in human diffuse large B cell lymphoma
    • Lenz G, Davis RE, Ngo VN, et al. Oncogenic CARD11 mutations in human diffuse large B cell lymphoma. Science. 2008;319(5870):1676-1679.
    • (2008) Science , vol.319 , Issue.5870 , pp. 1676-1679
    • Lenz, G.1    Davis, R.E.2    Ngo, V.N.3
  • 9
    • 66649127621 scopus 로고    scopus 로고
    • Mutations of multiple genes cause deregulation of NF-kappaB in diffuse large B-cell lymphoma
    • Compagno M, Lim WK, Grunn A, et al. Mutations of multiple genes cause deregulation of NF-kappaB in diffuse large B-cell lymphoma. Nature. 2009;459(7247):717-721.
    • (2009) Nature , vol.459 , Issue.7247 , pp. 717-721
    • Compagno, M.1    Lim, W.K.2    Grunn, A.3
  • 10
    • 0346727524 scopus 로고    scopus 로고
    • MicroRNAs modulate hematopoietic lineage differentiation
    • Chen CZ, Li L, Lodish HF, Bartel DP. MicroRNAs modulate hematopoietic lineage differentiation. Science. 2004;303(5654):83-86.
    • (2004) Science , vol.303 , Issue.5654 , pp. 83-86
    • Chen, C.Z.1    Li, L.2    Lodish, H.F.3    Bartel, D.P.4
  • 11
    • 75649139134 scopus 로고    scopus 로고
    • Physiological and pathological roles for microRNAs in the immune system
    • O'Connell RM, Rao DS, Chaudhuri AA, Baltimore D. Physiological and pathological roles for microRNAs in the immune system. Nat Rev Immunol. 2010;10(2):111-122.
    • (2010) Nat Rev Immunol. , vol.10 , Issue.2 , pp. 111-122
    • O'Connell, R.M.1    Rao, D.S.2    Chaudhuri, A.A.3    Baltimore, D.4
  • 13
    • 4344677175 scopus 로고    scopus 로고
    • Common logic of transcription factor and microRNA action
    • Hobert O. Common logic of transcription factor and microRNA action. Trends Biochem Sci. 2004;29(9):462-468.
    • (2004) Trends Biochem Sci. , vol.29 , Issue.9 , pp. 462-468
    • Hobert, O.1
  • 14
    • 84942803897 scopus 로고    scopus 로고
    • LymphomiRs: MicroRNAs with regulatory roles in lymphomas
    • Kozloski GA, Lossos IS. LymphomiRs: microRNAs with regulatory roles in lymphomas. Curr Opin Hematol. 2015;22(4):362-368.
    • (2015) Curr Opin Hematol. , vol.22 , Issue.4 , pp. 362-368
    • Kozloski, G.A.1    Lossos, I.S.2
  • 15
    • 34250877841 scopus 로고    scopus 로고
    • A mammalian microRNA expression atlas based on small RNA library sequencing
    • Landgraf P, Rusu M, Sheridan R, et al. A mammalian microRNA expression atlas based on small RNA library sequencing. Cell. 2007;129(7):1401-1414.
    • (2007) Cell. , vol.129 , Issue.7 , pp. 1401-1414
    • Landgraf, P.1    Rusu, M.2    Sheridan, R.3
  • 16
    • 66549101276 scopus 로고    scopus 로고
    • Patterns of microRNA expression characterize stages of human B-cell differentiation
    • Zhang J, Jima DD, Jacobs C, et al. Patterns of microRNA expression characterize stages of human B-cell differentiation. Blood. 2009;113(19):4586-4594.
    • (2009) Blood , vol.113 , Issue.19 , pp. 4586-4594
    • Zhang, J.1    Jima, D.D.2    Jacobs, C.3
  • 17
    • 65549112644 scopus 로고    scopus 로고
    • Differentiation stage-specific expression of microRNAs in B lymphocytes and diffuse large B-cell lymphomas
    • Malumbres R, Sarosiek KA, Cubedo E, et al. Differentiation stage-specific expression of microRNAs in B lymphocytes and diffuse large B-cell lymphomas. Blood. 2009;113(16):3754-3764.
    • (2009) Blood , vol.113 , Issue.16 , pp. 3754-3764
    • Malumbres, R.1    Sarosiek, K.A.2    Cubedo, E.3
  • 18
    • 79959259030 scopus 로고    scopus 로고
    • microRNAs are independent predictors of outcome in diffuse large B-cell lymphoma patients treated with R-CHOP
    • Alencar AJ, Malumbres R, Kozloski GA, et al. microRNAs are independent predictors of outcome in diffuse large B-cell lymphoma patients treated with R-CHOP. Clin Cancer Res. 2011;17(12):4125-4135.
    • (2011) Clin Cancer Res. , vol.17 , Issue.12 , pp. 4125-4135
    • Alencar, A.J.1    Malumbres, R.2    Kozloski, G.A.3
  • 19
    • 84878203252 scopus 로고    scopus 로고
    • The microRNA miR-181 is a critical cellular metabolic rheostat essential for NKT cell ontogenesis and lymphocyte development and homeostasis
    • Henao-Mejia J, Williams A, Goff LA, et al. The microRNA miR-181 is a critical cellular metabolic rheostat essential for NKT cell ontogenesis and lymphocyte development and homeostasis. Immunity. 2013;38(5):984-997.
    • (2013) Immunity , vol.38 , Issue.5 , pp. 984-997
    • Henao-Mejia, J.1    Williams, A.2    Goff, L.A.3
  • 20
    • 84899646555 scopus 로고    scopus 로고
    • miR-181a mediates metabolic shift in colon cancer cells via the PTEN/AKT pathway
    • Wei Z, Cui L, Mei Z, Liu M, Zhang D. miR-181a mediates metabolic shift in colon cancer cells via the PTEN/AKT pathway. FEBS Lett. 2014;588(9):1773-1779.
    • (2014) FEBS Lett. , vol.588 , Issue.9 , pp. 1773-1779
    • Wei, Z.1    Cui, L.2    Mei, Z.3    Liu, M.4    Zhang, D.5
  • 21
    • 84903536770 scopus 로고    scopus 로고
    • LPS induced miR-181a promotes pancreatic cancer cell migration via targeting PTEN and MAP2K4
    • Liu J, Xu D, Wang Q, Zheng D, Jiang X, Xu L. LPS induced miR-181a promotes pancreatic cancer cell migration via targeting PTEN and MAP2K4. Dig Dis Sci. 2014;59(7):1452-1460.
    • (2014) Dig Dis Sci. , vol.59 , Issue.7 , pp. 1452-1460
    • Liu, J.1    Xu, D.2    Wang, Q.3    Zheng, D.4    Jiang, X.5    Xu, L.6
  • 22
    • 79959259030 scopus 로고    scopus 로고
    • MicroRNAs are independent predictors of outcome in diffuse large B-cell lymphoma patients treated with R-CHOP
    • Alencar AJ, Malumbres R, Kozloski GA, et al. MicroRNAs are independent predictors of outcome in diffuse large B-cell lymphoma patients treated with R-CHOP. Clin Cancer Res. 2011;17(12):4125-4135.
    • (2011) Clin Cancer Res. , vol.17 , Issue.12 , pp. 4125-4135
    • Alencar, A.J.1    Malumbres, R.2    Kozloski, G.A.3
  • 23
    • 33947221062 scopus 로고    scopus 로고
    • T-cell protein tyrosine phosphatase, distinctively expressed in activated-B-cell-like diffuse large B-cell lymphomas, is the nuclear phosphatase of STAT6
    • Lu X, Chen J, Sasmono RT, et al. T-cell protein tyrosine phosphatase, distinctively expressed in activated-B-cell-like diffuse large B-cell lymphomas, is the nuclear phosphatase of STAT6. Mol Cell Biol. 2007;27(6):2166-2179.
    • (2007) Mol Cell Biol. , vol.27 , Issue.6 , pp. 2166-2179
    • Lu, X.1    Chen, J.2    Sasmono, R.T.3
  • 24
    • 0037443459 scopus 로고    scopus 로고
    • Potentiation of TRAIL-induced apoptosis in primary effusion lymphoma through azidothymidine-mediated inhibition of NF-kappa B
    • Ghosh SK, Wood C, Boise LH, et al. Potentiation of TRAIL-induced apoptosis in primary effusion lymphoma through azidothymidine-mediated inhibition of NF-kappa B. Blood. 2003;101(6):2321-2327.
    • (2003) Blood , vol.101 , Issue.6 , pp. 2321-2327
    • Ghosh, S.K.1    Wood, C.2    Boise, L.H.3
  • 25
    • 77449155831 scopus 로고    scopus 로고
    • Novel IL-21 signaling pathway up-regulates c-Myc and induces apoptosis of diffuse large B-cell lymphomas
    • Sarosiek KA, Malumbres R, Nechushtan H, Gentles AJ, Avisar E, Lossos IS. Novel IL-21 signaling pathway up-regulates c-Myc and induces apoptosis of diffuse large B-cell lymphomas. Blood. 2010;115(3):570-580.
    • (2010) Blood , vol.115 , Issue.3 , pp. 570-580
    • Sarosiek, K.A.1    Malumbres, R.2    Nechushtan, H.3    Gentles, A.J.4    Avisar, E.5    Lossos, I.S.6
  • 26
    • 84891884307 scopus 로고    scopus 로고
    • Targeted therapy by gene transfer of a monovalent antibody fragment against the Met oncogenic receptor
    • Vigna E, Pacchiana G, Chiriaco C, et al. Targeted therapy by gene transfer of a monovalent antibody fragment against the Met oncogenic receptor. J Mol Med (Berl). 2014;92(1):65-76.
    • (2014) J Mol Med (Berl) , vol.92 , Issue.1 , pp. 65-76
    • Vigna, E.1    Pacchiana, G.2    Chiriaco, C.3
  • 27
    • 84993731486 scopus 로고    scopus 로고
    • The molecular biology of diffuse large B-cell lymphoma
    • Frick M, Dörken B, Lenz G. The molecular biology of diffuse large B-cell lymphoma. Ther Adv Hematol. 2011;2(6):369-379.
    • (2011) Ther Adv Hematol. , vol.2 , Issue.6 , pp. 369-379
    • Frick, M.1    Dörken, B.2    Lenz, G.3
  • 28
    • 10244261528 scopus 로고    scopus 로고
    • Tracking CD40 signaling during germinal center development
    • Basso K, Klein U, Niu H, et al. Tracking CD40 signaling during germinal center development. Blood. 2004;104(13):4088-4096.
    • (2004) Blood , vol.104 , Issue.13 , pp. 4088-4096
    • Basso, K.1    Klein, U.2    Niu, H.3
  • 29
    • 84914093951 scopus 로고    scopus 로고
    • FOXP1 directly represses transcription of proapoptotic genes and cooperates with NF-κB to promote survival of human B cells
    • van Keimpema M, Grüneberg LJ, Mokry M, et al. FOXP1 directly represses transcription of proapoptotic genes and cooperates with NF-κB to promote survival of human B cells. Blood. 2014;124(23):3431-3440.
    • (2014) Blood , vol.124 , Issue.23 , pp. 3431-3440
    • Van Keimpema, M.1    Grüneberg, L.J.2    Mokry, M.3
  • 31
    • 55549103713 scopus 로고    scopus 로고
    • Prognostic significance of, and gene and microRNA expression signatures associated with, CEBPA mutations in cytogenetically normal acute myeloid leukemia with high-risk molecular features: A Cancer and Leukemia Group B Study
    • Marcucci G, Maharry K, Radmacher MD, et al. Prognostic significance of, and gene and microRNA expression signatures associated with, CEBPA mutations in cytogenetically normal acute myeloid leukemia with high-risk molecular features: a Cancer and Leukemia Group B Study. J Clin Oncol. 2008;26(31):5078-5087.
    • (2008) J Clin Oncol. , vol.26 , Issue.31 , pp. 5078-5087
    • Marcucci, G.1    Maharry, K.2    Radmacher, M.D.3
  • 32
    • 79251585678 scopus 로고    scopus 로고
    • Prognostic significance of expression of a single microRNA, miR-181a, in cytogenetically normal acute myeloid leukemia: A Cancer and Leukemia Group B study
    • Schwind S, Maharry K, Radmacher MD, et al. Prognostic significance of expression of a single microRNA, miR-181a, in cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study. J Clin Oncol. 2010;28(36):5257-5264.
    • (2010) J Clin Oncol. , vol.28 , Issue.36 , pp. 5257-5264
    • Schwind, S.1    Maharry, K.2    Radmacher, M.D.3
  • 33
    • 27244434788 scopus 로고    scopus 로고
    • A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia
    • Calin GA, Ferracin M, Cimmino A, et al. A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N Engl J Med. 2005;353(17):1793-1801.
    • (2005) N Engl J Med. , vol.353 , Issue.17 , pp. 1793-1801
    • Calin, G.A.1    Ferracin, M.2    Cimmino, A.3
  • 34
    • 0035137882 scopus 로고    scopus 로고
    • Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB
    • Baldwin AS. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB. J Clin Invest. 2001;107(3):241-246.
    • (2001) J Clin Invest. , vol.107 , Issue.3 , pp. 241-246
    • Baldwin, A.S.1
  • 35
    • 0036707512 scopus 로고    scopus 로고
    • Nuclear factor kappaB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity
    • Hinz M, Lemke P, Anagnostopoulos I, et al. Nuclear factor kappaB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity. J Exp Med. 2002;196(5):605-617.
    • (2002) J Exp Med. , vol.196 , Issue.5 , pp. 605-617
    • Hinz, M.1    Lemke, P.2    Anagnostopoulos, I.3
  • 36
    • 0034644474 scopus 로고    scopus 로고
    • Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
    • Deng L, Wang C, Spencer E, et al. Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Cell. 2000;103(2):351-361.
    • (2000) Cell. , vol.103 , Issue.2 , pp. 351-361
    • Deng, L.1    Wang, C.2    Spencer, E.3
  • 37
    • 84856641109 scopus 로고    scopus 로고
    • NF-κB, the first quarter-century: Remarkable progress and outstanding questions
    • Hayden MS, Ghosh S. NF-κB, the first quarter-century: remarkable progress and outstanding questions. Genes Dev. 2012;26(3):203-234.
    • (2012) Genes Dev. , vol.26 , Issue.3 , pp. 203-234
    • Hayden, M.S.1    Ghosh, S.2
  • 38
    • 0026783210 scopus 로고
    • I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: A mechanism for cytoplasmic retention
    • Beg AA, Ruben SM, Scheinman RI, Haskill S, Rosen CA, Baldwin AS Jr. I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention. Genes Dev. 1992;6(10):1899-1913.
    • (1992) Genes Dev. , vol.6 , Issue.10 , pp. 1899-1913
    • Beg, A.A.1    Ruben, S.M.2    Scheinman, R.I.3    Haskill, S.4    Rosen, C.A.5    Baldwin, A.S.6
  • 39
    • 0027078835 scopus 로고
    • I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding
    • Ganchi PA, Sun SC, Greene WC, Ballard DW. I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding. Mol Biol Cell. 1992;3(12):1339-1352.
    • (1992) Mol Biol Cell. , vol.3 , Issue.12 , pp. 1339-1352
    • Ganchi, P.A.1    Sun, S.C.2    Greene, W.C.3    Ballard, D.W.4
  • 40
    • 0031897457 scopus 로고    scopus 로고
    • The N-terminal domain of IkappaB alpha masks the nuclear localization signal(s) of p50 and c-Rel homodimers
    • Latimer M, Ernst MK, Dunn LL, Drutskaya M, Rice NR. The N-terminal domain of IkappaB alpha masks the nuclear localization signal(s) of p50 and c-Rel homodimers. Mol Cell Biol. 1998;18(5):2640-2649.
    • (1998) Mol Cell Biol. , vol.18 , Issue.5 , pp. 2640-2649
    • Latimer, M.1    Ernst, M.K.2    Dunn, L.L.3    Drutskaya, M.4    Rice, N.R.5
  • 41
    • 77955619456 scopus 로고    scopus 로고
    • miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines
    • Zhu W, Shan X, Wang T, Shu Y, Liu P. miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines. Int J Cancer. 2010;127(11):2520-2529.
    • (2010) Int J Cancer , vol.127 , Issue.11 , pp. 2520-2529
    • Zhu, W.1    Shan, X.2    Wang, T.3    Shu, Y.4    Liu, P.5
  • 42
    • 84863276383 scopus 로고    scopus 로고
    • miR-181a sensitizes a multidrug-resistant leukemia cell line K562/A02 to daunorubicin by targeting BCL-2
    • Li H, Hui L, Xu W. miR-181a sensitizes a multidrug-resistant leukemia cell line K562/A02 to daunorubicin by targeting BCL-2. Acta Biochim Biophys Sin (Shanghai). 2012;44(3):269-277.
    • (2012) Acta Biochim Biophys Sin (Shanghai) , vol.44 , Issue.3 , pp. 269-277
    • Li, H.1    Hui, L.2    Xu, W.3
  • 43
    • 79952124960 scopus 로고    scopus 로고
    • CD137 stimulation enhances the antilymphoma activity of anti-CD20 antibodies
    • Kohrt HE, Houot R, Goldstein MJ, et al. CD137 stimulation enhances the antilymphoma activity of anti-CD20 antibodies. Blood. 2011;117(8):2423-2432.
    • (2011) Blood , vol.117 , Issue.8 , pp. 2423-2432
    • Kohrt, H.E.1    Houot, R.2    Goldstein, M.J.3
  • 44
    • 33645306041 scopus 로고    scopus 로고
    • A loss-of-function RNA interference screen for molecular targets in cancer
    • Ngo VN, Davis RE, Lamy L, et al. A loss-of-function RNA interference screen for molecular targets in cancer. Nature. 2006;441(7089):106-110.
    • (2006) Nature , vol.441 , Issue.7089 , pp. 106-110
    • Ngo, V.N.1    Davis, R.E.2    Lamy, L.3
  • 45
    • 0742304482 scopus 로고    scopus 로고
    • The role of Rel/NF-kappaB transcription factors in B lymphocyte survival
    • Gerondakis S, Strasser A. The role of Rel/NF-kappaB transcription factors in B lymphocyte survival. Semin Immunol. 2003;15(3):159-166.
    • (2003) Semin Immunol. , vol.15 , Issue.3 , pp. 159-166
    • Gerondakis, S.1    Strasser, A.2
  • 46
    • 84858712873 scopus 로고    scopus 로고
    • NF-κB functioninBlymphocytes
    • Kaileh M, Sen R. NF-κB functioninBlymphocytes. Immunol Rev. 2012;246(1):254-271.
    • (2012) Immunol Rev. , vol.246 , Issue.1 , pp. 254-271
    • Kaileh, M.1    Sen, R.2
  • 47
    • 84907212728 scopus 로고    scopus 로고
    • Germinal center B cell maintenance and differentiation are controlled by distinct NF-κB transcription factor subunits
    • Heise N, De Silva NS, Silva K, et al. Germinal center B cell maintenance and differentiation are controlled by distinct NF-κB transcription factor subunits. J Exp Med. 2014;211(10):2103-2118.
    • (2014) J Exp Med. , vol.211 , Issue.10 , pp. 2103-2118
    • Heise, N.1    De Silva, N.S.2    Silva, K.3
  • 48
    • 70350304558 scopus 로고    scopus 로고
    • PI3 kinase signals BCR-dependent mature B cell survival
    • Srinivasan L, Sasaki Y, Calado DP, et al. PI3 kinase signals BCR-dependent mature B cell survival. Cell. 2009;139(3):573-586.
    • (2009) Cell. , vol.139 , Issue.3 , pp. 573-586
    • Srinivasan, L.1    Sasaki, Y.2    Calado, D.P.3
  • 49
    • 84877952103 scopus 로고    scopus 로고
    • MicroRNA-146 inhibits pro-inflammatory cytokine secretion through IL-1 receptor-associated kinase 1 in human gingival fibroblasts
    • Xie YF, Shu R, Jiang SY, Liu DL, Ni J, Zhang XL. MicroRNA-146 inhibits pro-inflammatory cytokine secretion through IL-1 receptor-associated kinase 1 in human gingival fibroblasts. J Inflamm (Lond). 2013;10(1):20.
    • (2013) J Inflamm (Lond) , vol.10 , Issue.1 , pp. 20
    • Xie, Y.F.1    Shu, R.2    Jiang, S.Y.3    Liu, D.L.4    Ni, J.5    Zhang, X.L.6
  • 50
    • 84861825526 scopus 로고    scopus 로고
    • MicroRNA-181b regulates NF-κB-mediated vascular inflammation
    • Sun X, Icli B, Wara AK, et al. MicroRNA-181b regulates NF-κB-mediated vascular inflammation. J Clin Invest. 2012;122(6):1973-1990.
    • (2012) J Clin Invest. , vol.122 , Issue.6 , pp. 1973-1990
    • Sun, X.1    Icli, B.2    Wara, A.K.3
  • 51
    • 56349133372 scopus 로고    scopus 로고
    • Pre-miRNA loop nucleotides control the distinct activities of mir-181a-1 and mir-181c in early T cell development
    • Liu G, Min H, Yue S, Chen CZ. Pre-miRNA loop nucleotides control the distinct activities of mir-181a-1 and mir-181c in early T cell development. PLoS One. 2008;3(10):e3592.
    • (2008) PLoS One , vol.3 , Issue.10 , pp. e3592
    • Liu, G.1    Min, H.2    Yue, S.3    Chen, C.Z.4
  • 52
    • 33947721625 scopus 로고    scopus 로고
    • miR-181a is an intrinsic modulator of T cell sensitivity and selection
    • Li QJ, Chau J, Ebert PJ, et al. miR-181a is an intrinsic modulator of T cell sensitivity and selection. Cell. 2007;129(1):147-161.
    • (2007) Cell. , vol.129 , Issue.1 , pp. 147-161
    • Li, Q.J.1    Chau, J.2    Ebert, P.J.3
  • 53
    • 53349129731 scopus 로고    scopus 로고
    • miR-181b negatively regulates activation-induced cytidine deaminase in B cells
    • de Yébenes VG, Belver L, Pisano DG, et al. miR-181b negatively regulates activation-induced cytidine deaminase in B cells. J Exp Med. 2008;205(10):2199-2206.
    • (2008) J Exp Med. , vol.205 , Issue.10 , pp. 2199-2206
    • De Yébenes, V.G.1    Belver, L.2    Pisano, D.G.3
  • 54
    • 77956901498 scopus 로고    scopus 로고
    • The promise of microRNA replacement therapy
    • Bader AG, Brown D, Winkler M. The promise of microRNA replacement therapy. Cancer Res. 2010;70(18):7027-7030.
    • (2010) Cancer Res. , vol.70 , Issue.18 , pp. 7027-7030
    • Bader, A.G.1    Brown, D.2    Winkler, M.3
  • 55
    • 84869219338 scopus 로고    scopus 로고
    • miR-34 - a microRNA replacement therapy is headed to the clinic
    • Bader AG. miR-34 - a microRNA replacement therapy is headed to the clinic. Front Genet. 2012;3:120.
    • (2012) Front Genet. , vol.3 , pp. 120
    • Bader, A.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.