Transcriptomics in Interferon-α-Treated Patients Identifies Inflammation-, Neuroplasticity- and Oxidative Stress-Related Signatures as Predictors and Correlates of Depression

Neuropsychopharmacology

Volumn 41, Issue 10, 2016, Pages 2502-2511

  Hepgul, Nilay ^a   Cattaneo, Annamaria ^a,b   Agarwal, Kosh ^c   Baraldi, Sara ^a   Borsini, Alessandra ^a   Bufalino, Chiara ^a   Forton, Daniel M ^d   Mondelli, Valeria ^a   Nikkheslat, Naghmeh ^a   Lopizzo, Nicola ^b   Riva, Marco A ^e   Russell, Alice ^a   Hotopf, Matthew ^a   Pariante, Carmine M ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF BRESCIA   (Italy)

^c KING S COLLEGE HOSPITAL   (United Kingdom)

^d ST GEORGE S HOSPITAL   (United Kingdom)

^e UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ALPHA INTERFERON; ANDROGEN; ANTIDEPRESSANT AGENT; CHEMOKINE RECEPTOR CXCR4; EPHRIN; EPHRIN RECEPTOR; FORMYLMETHIONYLLEUCYLPHENYLALANINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTEGRIN; INTERLEUKIN 1; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE 7; NETRIN; PHOSPHOLIPASE C; PROTHROMBIN; REACTIVE OXYGEN METABOLITE; RELAXIN; RHO GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR; RIBAVIRIN; THROMBIN; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1; TUMOR NECROSIS FACTOR ALPHA; ANTIVIRUS AGENT; KERATIN;

ADULT; ANTIVIRAL THERAPY; ARTICLE; CHRONIC HEPATITIS C; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE IDENTIFICATION; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MINI INTERNATIONAL NEUROPSYCHIATRIC INTERVIEW; NERVE CELL PLASTICITY; OXIDATIVE STRESS; PRIORITY JOURNAL; RNA ISOLATION; SIGNAL TRANSDUCTION; TRANSCRIPTOMICS; TREATMENT DURATION; UNEMPLOYMENT; UPREGULATION; ANALYSIS OF VARIANCE; BIOLOGY; BLOOD; CHEMICALLY INDUCED; COHORT ANALYSIS; DEPRESSION; DRUG EFFECTS; GENE EXPRESSION PROFILING; GENETICS; HEPATITIS C; MIDDLE AGED; PSYCHOLOGICAL RATING SCALE; QUESTIONNAIRE;

ADULT; ANALYSIS OF VARIANCE; ANTIVIRAL AGENTS; COHORT STUDIES; COMPUTATIONAL BIOLOGY; DEPRESSION; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HEPATITIS C; HUMANS; INTERFERON-ALPHA; KERATINS; MALE; MIDDLE AGED; OXIDATIVE STRESS; PSYCHIATRIC STATUS RATING SCALES; SIGNAL TRANSDUCTION; SURVEYS AND QUESTIONNAIRES;

EID: 84973904634     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2016.50     Document Type: Article

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