Nanodiagnostics: Leaving the research lab to enter the clinics?

Diagnosis

Volumn 1, Issue 4, 2014, Pages 305-309

  Baptista, Pedro Viana ^a  

^a UNIVERSIDADE NOVA DE LISBOA   (Portugal)

Author keywords

Gold nanoparticles; Molecular diagnostics; Nanodiagnostics; Nanotechnology; Point of care

Indexed keywords

BIOLOGICAL MARKER; GOLD NANOPARTICLE;

ARTICLE; DNA DETERMINATION; DNA RNA HYBRIDIZATION; HOSPITAL; LABORATORY TEST; MEDICAL RESEARCH; MOLECULAR DIAGNOSIS; MOLECULAR DIAGNOSTICS; NANODIAGNOSTICS; NANOTECHNOLOGY; PRIORITY JOURNAL; RNA ANALYSIS; SENSITIVITY ANALYSIS;

EID: 84973885168     PISSN: 21948011     EISSN: 2194802X     Source Type: Journal    
DOI: 10.1515/dx-2014-0055     Document Type: Article

References (23)

1. Thorley AJ, Tetley TD. New perspectives in nanomedicine. Pharmacol Ther 2013;140:176-85.
2. Jain KK. Nanodiagnostics: application of nanotechnology in molecular diagnostics. Exp Rev Mol Diagn 2003;3:153-61.
3. Sarpong K, Datta B. Nucleic-Acid-binding chromophores as efficient indicators of aptamer-target interactions. J Nucl Acids 2012;2012:247280.
4. Qian XM, Nie SM. Single-molecule and single-nanoparticle SERS: from fundamental mechanisms to biomedical applications. Chem Soc Rev 2008;37:912-20.
5. de la Escosura-Muñiz A, Ambrosi A, Alegret S, Merkoçi A. Electrochemical immunosensing using micro and nanoparticles. Methods Mol Biol 2009;504:145-55.
6. Thaxton CS, Georganopoulou DG, Mirkin CA. Gold nanoparticle probes for the detection of nucleic acid targets. Clin Chim Acta 2006;363:120-6.
7. Nam JM, Thaxton CS, Mirkin CA. Nanoparticle-based bio-bar codes for the ultrasensitive detection of proteins. Science 2003;301:1884-6.
8. Baptista PV, Koziol-Montewka M, Paluch-Oles J, Doria G, Franco R. Gold-nanoparticle-probe-based assay for rapid and direct detection of Mycobacterium tuberculosis DNA in clinical samples. Clin Chem 2006;52:1433-4.
9. Shinde SB, Fernandes CB, Patravale VB. Recent trends in in-vitro nanodiagnostics for detection of pathogens. J Control Release 2012;159:164-80.
10. Fernandes AR, Baptista PV. Cancer nanotechnology: prospects for cancer diagnostics and therapy - an update. Curr Cancer Ther Rev 2013;9:164-72.
11. Sperling RA, Parak WJ. Surface modification, functionalization and bioconjugation of colloidal inorganic nanoparticles. Philos Trans A Math Phys Eng Sci 2010;368:1333-83.
12. Cabral RM, Baptista PV. The chemistry and biology of gold nanoparticle-mediated photothermal therapy: promises and challenges. Nano LIFE 2013;3:1330001.
13. Dreaden EC, Alkilany AM, Huang X, Murphy CJ, El-Sayed MA. The golden age: gold nanoparticles for biomedicine. Chem Soc Rev 2012;41:2740-79.
14. Gubala V, Harris LF, Ricco AJ, Tan MX, Williams DE. Point of care diagnostics: status and future. Anal Chem 2012;84:487-515.
15. Rastogi SK, Gibson CM, Branen JR, Aston DE, Branen AL, Hrdlicka PJ. DNA detection on lateral flow test strips: enhanced signal sensitivity using LNA-conjugated gold nanoparticles. Chem Commun (Camb) 2012;48:7714-6.
16. Bernacka-Wojcik I, Lopes P, Vaz AC, Veigas B, Wojcik PJ, Simões P, et al. Bio-microfluidic platform for gold nanoprobe based DNA detection-application to Mycobacterium tuberculosis. Biosens Bioelectron 2013;48:87-93.
17. Veigas B, Jacob JM, Costa MN, Santos DS, Viveiros M, Inácio J, et al. Gold on paper-paper platform for Au-nanoprobe TB detection. Lab Chip 2012;12:4802-8.
18. Mankoff SP, Brander C, Ferrone S, Marincola FM. Lost in translation: obstacles to translational medicine. J Trans Med 2004;2:14.
19. Organisation for Economic Cooperation and Development: OECD guidelines for quality assurance in molecular genetic testing, 2007.
20. International Standardization Organization: ISO/TS 27687:2008 - Executive Summary Nanotechnologies - Terminology and definitions for nano-objects - Nanoparticle, nanofibre and nanoplate, 2008.
21. Storhoff JJ, Marla SS, Bao P, Hagenow S, Mehta H, Lucas A, et al. Gold nanoparticle-based detection of genomic DNA targets on microarrays using a novel optical detection system. Biosens Bioelectron 2004;19:875-83.
22. Obata K, Segawa O, Yakabe M. Development of a novel method for operating magnetic particles, magtration technology, and its use for automating nucleic acid purification. J Biosci Bioeng 2001;91:501-4.
23. Berensmeier S. Magnetic particles for the separation and purification of nucleic acids. Appl Microbiol Biotechnol 2006;73: 495-504.