IL-12 and IL-4 activate a CD39-dependent intrinsic peripheral tolerance mechanism in CD8+ T cells

European Journal of Immunology

Volumn 46, Issue 6, 2016, Pages 1438-1448

  Noble, Alistair ^a   Mehta, Hema ^a   Lovell, Andrew ^a   Papaioannou, Eleftheria ^a   Fairbanks, Lynette ^b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

CD39; CD8+ T cell; Interleukin 12; Interleukin 4; Regulatory T (Treg) cell; Tolerance

Indexed keywords

ADENOSINE A2A RECEPTOR; ADENOSINE A2A RECEPTOR AGONIST; ADENOSINE TRIPHOSPHATE; ALARMIN; ALLERGEN; CD39 ANTIGEN; GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; MITOGEN ACTIVATED PROTEIN KINASE; OVALBUMIN; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR T BET;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXIC T LYMPHOCYTE; FEMALE; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; IN VIVO STUDY; LYMPHOCYTE DIFFERENTIATION; MALE; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR ASSOCIATED LEUKOCYTE; UPREGULATION;

EID: 84973643904     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201545939     Document Type: Article

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