Racial/ethnic disparities in survival among patients with young-onset colorectal cancer

Journal of Clinical Oncology

Volumn 34, Issue 18, 2016, Pages 2148-2156

  Holowatyj, Andreana N ^a,b   Ruterbusch, Julie J ^a   Rozek, Laura S ^c   Cote, Michele L ^a,b   Stoffel, Elena M ^d  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KARMANOS CANCER INSTITUTE   (United States)

^c UNIVERSITY OF MICHIGAN SCHOOL OF PUBLIC HEALTH   (United States)

^d UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BLACK PERSON; CANCER MORTALITY; CANCER PATIENT; CANCER SPECIFIC SURVIVAL; CANCER SURVIVAL; CAUCASIAN; COLORECTAL CANCER; COMPARATIVE STUDY; CONTROLLED STUDY; ETHNIC DIFFERENCE; FEMALE; HISPANIC; HUMAN; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; ONSET AGE; OVERALL SURVIVAL; POVERTY; PRIORITY JOURNAL; RACE DIFFERENCE; YOUNG ADULT; COLORECTAL TUMOR; ETHNOLOGY; HEALTH DISPARITY; MORTALITY; PROPORTIONAL HAZARDS MODEL;

ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; AGE OF ONSET; COLORECTAL NEOPLASMS; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HEALTH STATUS DISPARITIES; HISPANIC AMERICANS; HUMANS; MALE; MIDDLE AGED; PROPORTIONAL HAZARDS MODELS;

EID: 84973622487     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2015.65.0994     Document Type: Article

References (43)

1. American Cancer Society: Colorectal Cancer Facts & Figures 2014-2016. Atlanta, GA, American Cancer Society, 2014.
2. Edwards BK, Ward E, Kohler BA, et al: Annual report to the nation on the status of cancer, 1975-2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates. Cancer 116:544-573, 2010
3. Robbins AS, Siegel RL, Jemal A: Racial disparities in stage-specific colorectal cancer mortality rates from 1985 to 2008. J Clin Oncol 30:401-405, 2012
4. Wallace K, Hill EG, Lewin DN, et al: Racial disparities in advanced-stage colorectal cancer survival. Cancer Causes Control 24:463-471, 2013
5. Soneji S, Iyer SS, Armstrong K, et al: Racial disparities in stage-specific colorectal cancer mortality: 1960-2005. Am J Public Health 100:1912-1916, 2010
6. Rim SH, Seeff L, Ahmed F, et al: Colorectal cancer incidence in the United States, 1999-2004 : An updated analysis of data from the National Program of Cancer Registries and the Surveillance, Epidemiology, and End Results Program. Cancer 115:1967-1976, 2009
7. Jemal A, Siegel R, Ward E, et al: Cancer statistics, 2008. CA Cancer J Clin 58:71-96, 2008
8. Laiyemo AO, Doubeni C, Pinsky PF, et al: Race and colorectal cancer disparities: Health-care utilization vs different cancer susceptibilities. J Natl Cancer Inst 102:538-546, 2010
9. Schroy PC III, Coe A, Chen CA, et al: Prevalence of advanced colorectal neoplasia in white and black patients undergoing screening colonoscopy in a safety-net hospital. Ann Intern Med 159:13-20, 2013
10. Meyer JE, Narang T, Schnoll-Sussman FH, et al: Increasing incidence of rectal cancer in patients aged younger than 40 years: An analysis of the surveillance, epidemiology, and end results database. Cancer 116:4354-4359, 2010
11. Siegel RL, Jemal A, Ward EM: Increase in incidence of colorectal cancer among young men and women in the United States. Cancer Epidemiol Biomarkers Prev 18:1695-1698, 2009
12. Theuer CP, Wagner JL, Taylor TH, et al: Racial and ethnic colorectal cancer patterns affect the cost-effectiveness of colorectal cancer screening in the United States. Gastroenterology 120:848-856, 2001
13. Chang DT, Pai RK, Rybicki LA, et al: Clinicopathologic and molecular features of sporadic early-onset colorectal adenocarcinoma: An adenocarcinoma with frequent signet ring cell differentiation, rectal and sigmoid involvement, and adverse morphologic features. Mod Pathol 25:1128-1139, 2012
14. Bleyer A, Barr R, Hayes-Lattin B, et al: The distinctive biology of cancer in adolescents and young adults. Nat Rev Cancer 8:288-298, 2008
15. Kneuertz PJ, Chang GJ, Hu CY, et al: Overtreatment of young adults with colon cancer: More intense treatments with unmatched survival gains. JAMA Surg 150:402-409, 2015
16. McMillan DC, McArdle CS: The impact of young age on cancer-specific and non-cancer-related survival after surgery for colorectal cancer: 10-year follow-up. Br J Cancer 101:557-560, 2009
17. Abdelsattar ZM, Wong SL, Regenbogen SE, et al: Colorectal cancer outcomes and treatment patterns in patients too young for average-risk screening. Cancer 122:929-934, 2016
18. Howlader N, Krapcho M, Garshell J, et al (eds): SEER Cancer Statistics Review, 1975-2012. Bethesda, MD, National Cancer Institute. http://seer.cancer.gov/csr/1975-2012/
19. National Cancer Institute: Surveillance, Epidemiology, and End Results Program. http://www.seer.cancer.gov
20. Phatak UR, Kao LS, Millas SG, et al: Interaction between age and race alters predicted survival in colorectal cancer. Ann Surg Oncol 20:3363-3369, 2013
21. DeSantis C, Naishadham D, Jemal A: Cancer statistics for African Americans, 2013. CA Cancer J Clin 63:151-166, 2013
22. Sineshaw HM, Robbins AS, Jemal A: Disparities in survival improvement for metastatic colorectal cancer by race/ethnicity and age in the United States. Cancer Causes Control 25:419-423, 2014
23. DeLancey JO, Thun MJ, Jemal A, et al: Recent trends in black-white disparities in cancer mortality. Cancer Epidemiol Biomarkers Prev 17:2908-2912, 2008
24. Irby K, Anderson WF, Henson DE, et al: Emerging and widening colorectal carcinoma disparities between blacks and whites in the United States (1975-2002). Cancer Epidemiol Biomarkers Prev 15:792-797, 2006
25. Chu KC, Tarone RE, Chow WH, et al: Temporal patterns in colorectal cancer incidence, survival, and mortality from 1950 through 1990. J Natl Cancer Inst 86:997-1006, 1994
26. Laryea JA, Siegel E, Klimberg S: Racial disparity in colorectal cancer: The role of equal treatment. Dis Colon Rectum 57:295-302, 2014
27. Bach PB, Schrag D, Brawley OW, et al: Survival of blacks and whites after a cancer diagnosis. JAMA 287:2106-2113, 2002
28. Gray R, Barnwell J, McConkey C, et al: Adjuvant chemotherapy versus observation in patients with colorectal cancer: A randomised study. Lancet 370:2020-2029, 2007
29. Yothers G, Sargent DJ, Wolmark N, et al: Outcomes among black patients with stage II and III colon cancer receiving chemotherapy: An analysis of ACCENT adjuvant trials. J Natl Cancer Inst 103:1498-1506, 2011
30. Jessup JM, Stewart A, Greene FL, et al: Adjuvant chemotherapy for stage III colon cancer: Implications of race/ethnicity, age, and differentiation. JAMA 294:2703-2711, 2005
31. Gryfe R, Kim H, Hsieh ET, et al: Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer. N Engl J Med 342:69-77, 2000
32. Phipps AI, Limburg PJ, Baron JA, et al: Association between molecular subtypes of colorectal cancer and patient survival. Gastroenterology148:77-87, 2015
33. Lieberman DA, Williams JL, Holub JL, et al: Race, ethnicity, and sex affect risk for polyps > 9mm in average-risk individuals. Gastroenterology 147:351-8, 2014; quiz e14-5
34. Carethers JM, Murali B, Yang B, et al: Influence of race on microsatellite instability and CD8+ T cell infiltration in colon cancer. PLoS One 9:e100461, 2014 [Erratum: PLoS One 9: e103699, 2014]
35. Sylvester BE, Huo D, Khramtsov A, et al: Molecular analysis of colorectal tumors within a diverse patient cohort at a single institution. Clin Cancer Res 18:350-359, 2012
36. Carethers JM, Koi M, Tseng-Rogenski SS: EMAST is a form of microsatellite instability that is initiated by inflammation and modulates colorectal cancer progression. Genes (Basel) 6:185-205, 2015
37. Schellerer VS, Merkel S, Schumann SC, et al: Despite aggressive histopathology survival is not impaired in young patients with colorectal cancer: CRC in patients under 50 years of age. Int J Colorectal Dis 27:71-79, 2012
38. Yantiss RK, Goodarzi M, Zhou XK, et al: Clinical, pathologic, and molecular features of early-onset colorectal carcinoma. Am J Surg Pathol 33:572-582, 2009
39. Agrawal S, Bhupinderjit A, Bhutani MS, et al: Colorectal cancer in African Americans. Am J Gastroenterol 100:515-523; discussion 514, 2005 [Erratum: Am J Gastroenterol 100:1432, 2005]
40. Carethers JM: Screening for colorectal cancer in African Americans: Determinants and rationale for an earlier age to commence screening. Dig Dis Sci 60:711-721, 2015
41. Rex DK, Johnson DA, Anderson JC, et al: American College of Gastroenterology guidelines for colorectal cancer screening 2009 [corrected]. Am J Gastroenterol 104:739-750, 2009
42. National Comprehensive Care Network: Colon Cancer. http://www.nccn.org/professionals/physician-gls/pdf/colon.pdf
43. Guindalini RS, Win AK, Gulden C, et al: Mutation spectrum and risk of colorectal cancer in African American families with Lynch syndrome. Gastroenterology 149:1446-1453, 2015