메뉴 건너뛰기




Volumn 6, Issue , 2016, Pages

Aerobic Exercise and Pharmacological Treatments Counteract Cachexia by Modulating Autophagy in Colon Cancer

Author keywords

[No Author keywords available]

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE; AICA RIBONUCLEOTIDE; RAPAMYCIN; RIBONUCLEOTIDE;

EID: 84973402052     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep26991     Document Type: Article
Times cited : (139)

References (59)
  • 1
    • 84918815964 scopus 로고    scopus 로고
    • Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012
    • Ferlay, J. et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int. J. Cancer 136, E359-E386 (2015).
    • (2015) Int. J. Cancer , vol.136 , pp. E359-E386
    • Ferlay, J.1
  • 3
    • 50549084365 scopus 로고    scopus 로고
    • Influence of pre- and postdiagnosis physical activity on mortality in breast cancer survivors: The health, eating, activity, and lifestyle study
    • Irwin, M. L. et al. Influence of pre- and postdiagnosis physical activity on mortality in breast cancer survivors: the health, eating, activity, and lifestyle study. J. Clin. Oncol. 26, 3958-3964 (2008).
    • (2008) J. Clin. Oncol. , vol.26 , pp. 3958-3964
    • Irwin, M.L.1
  • 4
    • 33747050415 scopus 로고    scopus 로고
    • Physical activity and survival after colorectal cancer diagnosis
    • Meyerhardt, J. A. et al. Physical activity and survival after colorectal cancer diagnosis. J. Clin. Oncol. 24, 3527-3534 (2006).
    • (2006) J. Clin. Oncol. , vol.24 , pp. 3527-3534
    • Meyerhardt, J.A.1
  • 5
    • 33747058785 scopus 로고    scopus 로고
    • Cancer survival: Time to get moving? Data accumulate suggesting a link between physical activity and cancer survival
    • Mark-Wahnefried, W. Cancer survival: time to get moving? Data accumulate suggesting a link between physical activity and cancer survival. J. Clin. Oncol. 24, 3517-3518 (2006).
    • (2006) J. Clin. Oncol. , vol.24 , pp. 3517-3518
    • Mark-Wahnefried, W.1
  • 6
    • 4444354268 scopus 로고    scopus 로고
    • Physical activity levels among breast cancer survivors
    • Irwin, M. L. et al. Physical activity levels among breast cancer survivors. Med. Sci. Sports Exerc. 36, 1484-1491 (2004).
    • (2004) Med. Sci. Sports Exerc. , vol.36 , pp. 1484-1491
    • Irwin, M.L.1
  • 7
    • 53049107462 scopus 로고    scopus 로고
    • Health-related quality of life in breast cancer patients: A bibliographic review of the literature from 1974 to 2007
    • Montazeri, A. Health-related quality of life in breast cancer patients: a bibliographic review of the literature from 1974 to 2007. J. Exp. Clin. Cancer Res. 27, 32 (2008).
    • (2008) J. Exp. Clin. Cancer Res. , vol.27 , pp. 32
    • Montazeri, A.1
  • 8
    • 55749085001 scopus 로고    scopus 로고
    • Cachexia: A new definition
    • Evans, W. J. et al. Cachexia: a new definition. Clin. Nutr. 27, 793-799 (2008).
    • (2008) Clin. Nutr. , vol.27 , pp. 793-799
    • Evans, W.J.1
  • 9
    • 79955399340 scopus 로고    scopus 로고
    • Definition and classification of cancer cachexia: An international consensus
    • Fearon, K. et al. Definition and classification of cancer cachexia: an international consensus. Lancet Oncol. 12, 489-495 (2011).
    • (2011) Lancet Oncol. , vol.12 , pp. 489-495
    • Fearon, K.1
  • 10
    • 34447628323 scopus 로고    scopus 로고
    • Loss of skeletal muscle mass in aging: Examining the relationship of starvation, sarcopenia and cachexia
    • Thomas, D. R. Loss of skeletal muscle mass in aging: examining the relationship of starvation, sarcopenia and cachexia. Clin. Nutr. 26, 389-399 (2007).
    • (2007) Clin. Nutr. , vol.26 , pp. 389-399
    • Thomas, D.R.1
  • 11
    • 84887493598 scopus 로고    scopus 로고
    • NF-kappaB-mediated Pax7 dysregulation in the muscle microenvironment promotes cancer cachexia
    • He, W. A. et al. NF-kappaB-mediated Pax7 dysregulation in the muscle microenvironment promotes cancer cachexia. J. Clin. Invest 123, 4821-4835 (2013).
    • (2013) J. Clin. Invest , vol.123 , pp. 4821-4835
    • He, W.A.1
  • 12
    • 79951882924 scopus 로고    scopus 로고
    • Cancer cachexia: Traditional therapies and novel molecular mechanism-based approaches to treatment
    • Kumar, N. B. et al. Cancer cachexia: traditional therapies and novel molecular mechanism-based approaches to treatment. Curr. Treat. Options. Oncol. 11, 107-117 (2010).
    • (2010) Curr. Treat. Options. Oncol. , vol.11 , pp. 107-117
    • Kumar, N.B.1
  • 13
    • 0035238403 scopus 로고    scopus 로고
    • Resistance exercise training attenuates wasting of the extensor digitorum longus muscle in mice bearing the colon-26 adenocarcinoma
    • al-Majid, S. & McCarthy, D. O. Resistance exercise training attenuates wasting of the extensor digitorum longus muscle in mice bearing the colon-26 adenocarcinoma. Biol. Res. Nurs. 2, 155-166 (2001).
    • (2001) Biol. Res. Nurs. , vol.2 , pp. 155-166
    • Al-Majid, S.1    McCarthy, D.O.2
  • 14
    • 84873378527 scopus 로고    scopus 로고
    • Exercise metabolism and the molecular regulation of skeletal muscle adaptation
    • Egan, B. & Zierath, J. R. Exercise metabolism and the molecular regulation of skeletal muscle adaptation. Cell Metab 17, 162-184 (2013).
    • (2013) Cell Metab , vol.17 , pp. 162-184
    • Egan, B.1    Zierath, J.R.2
  • 15
    • 27644471080 scopus 로고    scopus 로고
    • Dystrophin glycoprotein complex dysfunction: A regulatory link between muscular dystrophy and cancer cachexia
    • Acharyya, S. et al. Dystrophin glycoprotein complex dysfunction: a regulatory link between muscular dystrophy and cancer cachexia. Cancer Cell 8, 421-432 (2005).
    • (2005) Cancer Cell , vol.8 , pp. 421-432
    • Acharyya, S.1
  • 16
    • 65649085174 scopus 로고    scopus 로고
    • Exercise: It's the real thing!
    • Hawley, J. A. & Holloszy, J. O. Exercise: it's the real thing! Nutr. Rev. 67, 172-178 (2009).
    • (2009) Nutr. Rev. , vol.67 , pp. 172-178
    • Hawley, J.A.1    Holloszy, J.O.2
  • 17
    • 48449094498 scopus 로고    scopus 로고
    • AMPK and PPARdelta agonists are exercise mimetics
    • Narkar, V. A. et al. AMPK and PPARdelta agonists are exercise mimetics. Cell 134, 405-415 (2008).
    • (2008) Cell , vol.134 , pp. 405-415
    • Narkar, V.A.1
  • 18
    • 80051711502 scopus 로고    scopus 로고
    • Antagonistic control of muscle cell size by AMPK and mTORC1
    • Mounier, R. et al. Antagonistic control of muscle cell size by AMPK and mTORC1. Cell Cycle 10, 2640-2646 (2011).
    • (2011) Cell Cycle , vol.10 , pp. 2640-2646
    • Mounier, R.1
  • 19
    • 79551598347 scopus 로고    scopus 로고
    • AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
    • Kim, J., Kundu, M., Viollet, B. & Guan, K. L. AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat. Cell Biol. 13, 132-141 (2011).
    • (2011) Nat. Cell Biol. , vol.13 , pp. 132-141
    • Kim, J.1    Kundu, M.2    Viollet, B.3    Guan, K.L.4
  • 20
    • 84855532023 scopus 로고    scopus 로고
    • 3 a and interaction with Ulk1
    • Sanchez, A. M. et al. AMPK promotes skeletal muscle autophagy through activation of forkhead FoxO3 a and interaction with Ulk1. J. Cell Biochem. 113, 695-710 (2012).
    • (2012) J. Cell Biochem. , vol.113 , pp. 695-710
    • Sanchez, A.M.1
  • 21
    • 42949139481 scopus 로고    scopus 로고
    • AMPK phosphorylation of raptor mediates a metabolic checkpoint
    • Gwinn, D. M. et al. AMPK phosphorylation of raptor mediates a metabolic checkpoint. Mol. Cell 30, 214-226 (2008).
    • (2008) Mol. Cell , vol.30 , pp. 214-226
    • Gwinn, D.M.1
  • 22
    • 41449113346 scopus 로고    scopus 로고
    • Coordinate activation of autophagy and the proteasome pathway by FoxO transcription factor
    • Zhao, J., Brault, J. J., Schild, A. & Goldberg, A. L. Coordinate activation of autophagy and the proteasome pathway by FoxO transcription factor. Autophagy. 4, 378-380 (2008).
    • (2008) Autophagy. , vol.4 , pp. 378-380
    • Zhao, J.1    Brault, J.J.2    Schild, A.3    Goldberg, A.L.4
  • 23
    • 54849404282 scopus 로고    scopus 로고
    • Skeletal muscle is a primary target of SOD1G93A-mediated toxicity
    • Dobrowolny, G. et al. Skeletal muscle is a primary target of SOD1G93A-mediated toxicity. Cell Metab 8, 425-436 (2008).
    • (2008) Cell Metab , vol.8 , pp. 425-436
    • Dobrowolny, G.1
  • 24
    • 36448940798 scopus 로고    scopus 로고
    • 3 controls autophagy in skeletal muscle in vivo
    • Mammucari, C. et al. FoxO3 controls autophagy in skeletal muscle in vivo. Cell Metab 6, 458-471 (2007).
    • (2007) Cell Metab , vol.6 , pp. 458-471
    • Mammucari, C.1
  • 25
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine, B. & Kroemer, G. Autophagy in the pathogenesis of disease. Cell 132, 27-42 (2008).
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 26
    • 84904496299 scopus 로고    scopus 로고
    • Autophagy is Impaired in the Tibialis Anterior of Dystrophin Null Mice
    • Spitali, P. et al. Autophagy is Impaired in the Tibialis Anterior of Dystrophin Null Mice. PLoS Curr. 5, (2013).
    • (2013) PLoS Curr. , vol.5
    • Spitali, P.1
  • 27
    • 70449927247 scopus 로고    scopus 로고
    • Autophagy is required to maintain muscle mass
    • Masiero, E. et al. Autophagy is required to maintain muscle mass. Cell Metab 10, 507-515 (2009).
    • (2009) Cell Metab , vol.10 , pp. 507-515
    • Masiero, E.1
  • 28
    • 84877628647 scopus 로고    scopus 로고
    • Autophagy in human health and disease
    • Choi, A. M., Ryter, S. W. & Levine, B. Autophagy in human health and disease. N. Engl. J. Med. 368, 1845-1846 (2013).
    • (2013) N. Engl. J. Med. , vol.368 , pp. 1845-1846
    • Choi, A.M.1    Ryter, S.W.2    Levine, B.3
  • 29
    • 77955388009 scopus 로고    scopus 로고
    • Molecular, cellular and physiological characterization of the cancer cachexia-inducing C26 colon carcinoma in mouse
    • Aulino, P. et al. Molecular, cellular and physiological characterization of the cancer cachexia-inducing C26 colon carcinoma in mouse. BMC. Cancer 10, 363 (2010).
    • (2010) BMC. Cancer , vol.10 , pp. 363
    • Aulino, P.1
  • 30
    • 63849120127 scopus 로고    scopus 로고
    • Effects of environmental enrichment on the amyotrophic lateral sclerosis mouse model
    • Sorrells, A. D. et al. Effects of environmental enrichment on the amyotrophic lateral sclerosis mouse model. Lab Anim 43, 182-190 (2009).
    • (2009) Lab Anim , vol.43 , pp. 182-190
    • Sorrells, A.D.1
  • 31
    • 0037318822 scopus 로고    scopus 로고
    • Signalling pathways that mediate skeletal muscle hypertrophy and atrophy
    • Glass, D. J. Signalling pathways that mediate skeletal muscle hypertrophy and atrophy. Nat. Cell Biol. 5, 87-90 (2003).
    • (2003) Nat. Cell Biol. , vol.5 , pp. 87-90
    • Glass, D.J.1
  • 32
    • 84875192592 scopus 로고    scopus 로고
    • Autophagic degradation contributes to muscle wasting in cancer cachexia
    • Penna, F. et al. Autophagic degradation contributes to muscle wasting in cancer cachexia. Am. J. Pathol. 182, 1367-1378 (2013).
    • (2013) Am. J. Pathol. , vol.182 , pp. 1367-1378
    • Penna, F.1
  • 33
    • 84987673756 scopus 로고    scopus 로고
    • Pompe disease: From pathophysiology to therapy and back again
    • Lim, J. A., Li, L. & Raben, N. Pompe disease: from pathophysiology to therapy and back again. Front Aging Neurosci. 6, 177 (2014).
    • (2014) Front Aging Neurosci. , vol.6 , pp. 177
    • Lim, J.A.1    Li, L.2    Raben, N.3
  • 34
    • 84863393597 scopus 로고    scopus 로고
    • Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis
    • He, C. et al. Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis. Nature 481, 511-515 (2012).
    • (2012) Nature , vol.481 , pp. 511-515
    • He, C.1
  • 35
    • 84864124772 scopus 로고    scopus 로고
    • AMPK activation stimulates autophagy and ameliorates muscular dystrophy in the mdx mouse diaphragm
    • Pauly, M. et al. AMPK activation stimulates autophagy and ameliorates muscular dystrophy in the mdx mouse diaphragm. Am. J. Pathol. 181, 583-592 (2012).
    • (2012) Am. J. Pathol. , vol.181 , pp. 583-592
    • Pauly, M.1
  • 36
    • 78149319082 scopus 로고    scopus 로고
    • Autophagy is defective in collagen VI muscular dystrophies, and its reactivation rescues myofiber degeneration
    • Grumati, P. et al. Autophagy is defective in collagen VI muscular dystrophies, and its reactivation rescues myofiber degeneration. Nat. Med. 16, 1313-1320 (2010).
    • (2010) Nat. Med. , vol.16 , pp. 1313-1320
    • Grumati, P.1
  • 37
    • 8344242220 scopus 로고    scopus 로고
    • Autophagy in health and disease: A double-edged sword
    • Shintani, T. & Klionsky, D. J. Autophagy in health and disease: a double-edged sword. Science 306, 990-995 (2004).
    • (2004) Science , vol.306 , pp. 990-995
    • Shintani, T.1    Klionsky, D.J.2
  • 39
    • 77949272095 scopus 로고    scopus 로고
    • Evolving classification systems for cancer cachexia: Ready for clinical practice?
    • Blum, D. et al. Evolving classification systems for cancer cachexia: ready for clinical practice? Support. Care Cancer 18, 273-279 (2010).
    • (2010) Support. Care Cancer , vol.18 , pp. 273-279
    • Blum, D.1
  • 41
    • 0034163376 scopus 로고    scopus 로고
    • Symptom and quality of life survey of medical oncology patients at a veterans affairs medical center: A role for symptom assessment
    • Chang, V. T., Hwang, S. S., Feuerman, M. & Kasimis, B. S. Symptom and quality of life survey of medical oncology patients at a veterans affairs medical center: a role for symptom assessment. Cancer 88, 1175-1183 (2000).
    • (2000) Cancer , vol.88 , pp. 1175-1183
    • Chang, V.T.1    Hwang, S.S.2    Feuerman, M.3    Kasimis, B.S.4
  • 42
    • 0025263860 scopus 로고
    • Experimental cancer cachexia induced by transplantable colon 26 adenocarcinoma in mice
    • Tanaka, Y. et al. Experimental cancer cachexia induced by transplantable colon 26 adenocarcinoma in mice. Cancer Res. 50, 2290-2295 (1990).
    • (1990) Cancer Res. , vol.50 , pp. 2290-2295
    • Tanaka, Y.1
  • 43
    • 63349100316 scopus 로고    scopus 로고
    • Orally available selective melanocortin-4 receptor antagonists stimulate food intake and reduce cancer-induced cachexia in mice
    • Weyermann, P. et al. Orally available selective melanocortin-4 receptor antagonists stimulate food intake and reduce cancer-induced cachexia in mice. PLoS One 4, e4774 (2009).
    • (2009) PLoS One , vol.4 , pp. e4774
    • Weyermann, P.1
  • 44
    • 84875527893 scopus 로고    scopus 로고
    • Substrains of inbred mice differ in their physical activity as a behavior
    • Coletti, D. et al. Substrains of inbred mice differ in their physical activity as a behavior. Scientific World Journal. 2013, 237260 (2013).
    • (2013) Scientific World Journal. , vol.2013 , pp. 237260
    • Coletti, D.1
  • 45
    • 84954550959 scopus 로고    scopus 로고
    • Spontaneous physical activity downregulates pax7 in cancer cachexia
    • 2016
    • Coletti, D. et al. Spontaneous Physical Activity Downregulates Pax7 in Cancer Cachexia. Stem Cells Int. 2016, 2016:6729268. doi: 10.1155/2016/6729268 (2016).
    • (2016) Stem Cells Int. , vol.2016 , pp. 6729268
    • Coletti, D.1
  • 46
    • 84876414410 scopus 로고    scopus 로고
    • Mechanisms for fiber-type specificity of skeletal muscle atrophy
    • Wang, Y. & Pessin, J. E. Mechanisms for fiber-type specificity of skeletal muscle atrophy. Curr. Opin. Clin. Nutr. Metab Care 16, 243-250 (2013).
    • (2013) Curr. Opin. Clin. Nutr. Metab Care , vol.16 , pp. 243-250
    • Wang, Y.1    Pessin, J.E.2
  • 47
    • 0028783551 scopus 로고
    • Apoptosis, DNA damage and ubiquitin expression in normal and mdx muscle fibers after exercise
    • Sandri, M. et al. Apoptosis, DNA damage and ubiquitin expression in normal and mdx muscle fibers after exercise. FEBS Lett. 373, 291-295 (1995).
    • (1995) FEBS Lett. , vol.373 , pp. 291-295
    • Sandri, M.1
  • 48
    • 0030638154 scopus 로고    scopus 로고
    • Exercise induces myonuclear ubiquitination and apoptosis in dystrophin-deficient muscle of mice
    • Sandri, M. et al. Exercise induces myonuclear ubiquitination and apoptosis in dystrophin-deficient muscle of mice. J. Neuropathol. Exp. Neurol. 56, 45-57 (1997).
    • (1997) J. Neuropathol. Exp. Neurol. , vol.56 , pp. 45-57
    • Sandri, M.1
  • 49
    • 77957686764 scopus 로고    scopus 로고
    • Quantitation of "autophagic flux" in mature skeletal muscle
    • Ju, J. S., Varadhachary, A. S., Miller, S. E. & Weihl, C. C. Quantitation of "autophagic flux" in mature skeletal muscle. Autophagy. 6, 929-935 (2010).
    • (2010) Autophagy. , vol.6 , pp. 929-935
    • Ju, J.S.1    Varadhachary, A.S.2    Miller, S.E.3    Weihl, C.C.4
  • 50
    • 84890283002 scopus 로고    scopus 로고
    • Misregulation of autophagy and protein degradation systems in myopathies and muscular dystrophies
    • Sandri, M., Coletto, L., Grumati, P. & Bonaldo, P. Misregulation of autophagy and protein degradation systems in myopathies and muscular dystrophies. J. Cell Sci. 126, 5325-5333 (2013).
    • (2013) J. Cell Sci. , vol.126 , pp. 5325-5333
    • Sandri, M.1    Coletto, L.2    Grumati, P.3    Bonaldo, P.4
  • 51
    • 77953531909 scopus 로고    scopus 로고
    • Autophagy inhibition induces atrophy and myopathy in adult skeletal muscles
    • Masiero, E. & Sandri, M. Autophagy inhibition induces atrophy and myopathy in adult skeletal muscles. Autophagy. 6, 307-309 (2010).
    • (2010) Autophagy. , vol.6 , pp. 307-309
    • Masiero, E.1    Sandri, M.2
  • 52
    • 24944559356 scopus 로고    scopus 로고
    • Collagen VI related muscle disorders
    • Lampe, A. K. & Bushby, K. M. Collagen VI related muscle disorders. J. Med. Genet. 42, 673-685 (2005).
    • (2005) J. Med. Genet. , vol.42 , pp. 673-685
    • Lampe, A.K.1    Bushby, K.M.2
  • 53
    • 84870479343 scopus 로고    scopus 로고
    • Autophagy as a new therapeutic target in Duchenne muscular dystrophy
    • De, P. C. et al. Autophagy as a new therapeutic target in Duchenne muscular dystrophy. Cell Death. Dis. 3, e418 (2012).
    • (2012) Cell Death. Dis. , vol.3 , pp. e418
    • De, P.C.1
  • 54
    • 79953668113 scopus 로고    scopus 로고
    • Autophagy induction rescues muscular dystrophy
    • Grumati, P., Coletto, L., Sandri, M. & Bonaldo, P. Autophagy induction rescues muscular dystrophy. Autophagy. 7, 426-428 (2011).
    • (2011) Autophagy. , vol.7 , pp. 426-428
    • Grumati, P.1    Coletto, L.2    Sandri, M.3    Bonaldo, P.4
  • 55
    • 84866648580 scopus 로고    scopus 로고
    • Combined effect of AMPK/PPAR agonists and exercise training in mdx mice functional performance
    • Bueno Junior, C. R. et al. Combined effect of AMPK/PPAR agonists and exercise training in mdx mice functional performance. PLoS One 7, e45699 (2012).
    • (2012) PLoS One , vol.7 , pp. e45699
    • Bueno Junior, C.R.1
  • 56
    • 84898758480 scopus 로고    scopus 로고
    • Effects of short-term metformin therapy associated with levothyroxine dose decrement on TSH and thyroid hormone levels in patients with thyroid cancer
    • Mousavi, Z., Dourandish, L., Rokni, H., Sadeghi, R. & Rasoul, Z. S. Effects of short-term metformin therapy associated with levothyroxine dose decrement on TSH and thyroid hormone levels in patients with thyroid cancer. Minerva Endocrinol. 39, 59-65 (2014).
    • (2014) Minerva Endocrinol. , vol.39 , pp. 59-65
    • Mousavi, Z.1    Dourandish, L.2    Rokni, H.3    Sadeghi, R.4    Rasoul, Z.S.5
  • 57
    • 84893764401 scopus 로고    scopus 로고
    • Molecular determinants of outcome with mammalian target of rapamycin inhibition in endometrial cancer
    • Mackay, H. J. et al. Molecular determinants of outcome with mammalian target of rapamycin inhibition in endometrial cancer. Cancer 120, 603-610 (2014).
    • (2014) Cancer , vol.120 , pp. 603-610
    • Mackay, H.J.1
  • 58
    • 84960808676 scopus 로고    scopus 로고
    • Voluntary running suppresses tumor growth through epinephrine- and il-6-dependent nk cell mobilization and redistribution
    • Pedersen, L. et al. Voluntary Running Suppresses Tumor Growth through Epinephrine- and IL-6-Dependent NK Cell Mobilization and Redistribution. Cell Metab 23, 554-562 (2016).
    • (2016) Cell Metab , vol.23 , pp. 554-562
    • Pedersen, L.1
  • 59
    • 77951579326 scopus 로고    scopus 로고
    • Wheel running and environmental enrichment differentially modify exon-specific BDNF expression in the hippocampus of wild-type and pre-motor symptomatic male and female Huntington's disease mice
    • Zajac, M. S. et al. Wheel running and environmental enrichment differentially modify exon-specific BDNF expression in the hippocampus of wild-type and pre-motor symptomatic male and female Huntington's disease mice. Hippocampus 20, 621-636 (2010).
    • (2010) Hippocampus , vol.20 , pp. 621-636
    • Zajac, M.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.